070302-分析化学

质谱成像

2007-09--2012-07   中国科学院上海药物研究所   理学博士
2003-09--2007-07   吉林大学   药学学士

   

2020-04~现在, 中国科学院化学研究所, 副研究员
2015-06~2020-04,中国科学院化学研究所, 助理研究员
2012-09~2015-06,中国科学院化学研究所, 博士后
2007-09~2012-07,中国科学院上海药物研究所, 理学博士
2003-09~2007-07,吉林大学, 药学学士

   

（1） Mass spectrometry imaging reveals the in situ distribution and metabolic effects of Fullerenes, Analytical Chemistry, 2025, 
（2） Rapid analysis and authentication of Chinese propolis using nanoelectrospray ionization mass spectrometry combined with machine learning, FOOD CHEMISTRY, 2024, 第 6 作者  通讯作者
（3） Conjugate Polymer Anchor Enhancing Matrix Vacuum Stability and Improving MALDI MSI via Ion Bond, ADVANCED SCIENCE, 2024, 第 5 作者  通讯作者
（4） Conjugate polymer anchor enhancing matrix vacuum stability and improving MALDI MSI via ion bond, Advanced Science, 2024, 
（5） Rapid analysis and authentication of Chinese propolis using nanoelectrospray ionization mass spectrometry combined with machine learning, Food Chemistry, 2024, 
（6） Specific Spleen-Accumulated NIR-II Fluorescent Probe for Imaging-Guided Splenic Operation, Adv. Healthcare Mater., 2023, 第 5 作者
（7） Revealing the In Situ Behavior of Aggregation-Induced Emission Nanoparticles and Their Biometabolic Effects via Mass Spectrometry Imaging, ACS NANO, 2023, 第 4 作者
（8） Urine and serum metabolic profiling combined with machine learning for autoimmune disease discrimination and classification, CHEMICAL COMMUNICATIONS, 2023, 第 7 作者  通讯作者
（9） Biofluid metabolic profiling for lung cancer screening via reactive matrix-assisted laser desorption ionization mass spectrometry, Analytical Chemistry, 2023, 
（10） Altered prefrontal neurochemistry in the DJ���1 knockout mouse model of Parkinson���s disease: complementary semi���quantitative analyses with in vivo magnetic resonance spectroscopy and MALDI���MSI, Analytical and Bioanalytical Chemistry, 2022, 第 2 作者
（11） Development of an Automatic Ultrasonic Matrix Sprayer for Matrix-Assisted Laser Desorption/lonization Mass Spectrometry Imaging, ANALYTICAL CHEMISTRY, 2022, 第 6 作者  通讯作者
（12） Laser Desorption/Ionization Mass Spectrometry Imaging: A New Tool to See through Nanoscale Particles in Biological Systems, CHEMISTRY-A EUROPEAN JOURNAL, 2022, 第 4 作者  通讯作者
（13） High Speed Mass Measurement of a Single Metal-Organic Framework Nanocrystal in a Paul Trap, ANALYTICAL CHEMISTRY, 2022, 第 2 作者
（14） Rapid screening for genitourinary cancers: mass spectrometry-based metabolic fingerprinting of urine, CHEMICAL COMMUNICATIONS, 2022, 第 6 作者  通讯作者
（15） Pocket-Size "MasSpec Pointer" for Ambient Ionization Mass Spectrometry, ANALYTICAL CHEMISTRY, 2021, 第 5 作者
（16） MALDI-TOF/TOF tandem mass spectrometry imaging reveals non-uniform distribution of disaccharide isomers in plant tissues, FOOD CHEMISTRY, 2021, 第 4 作者
（17） Application of Graphdiyne in Surface-Assisted Laser Desorption Ionization Mass Spectrometry, ACS APPLIED MATERIALS & INTERFACES, 2021, 第 6 作者
（18） Mass Spectrometry Imaging Reveals In Situ Behaviors of Multiple Components in Aerosol Particles, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 4 作者
（19） Mass spectrometry for multi-dimensional characterization of natural and synthetic materials at the nanoscale, CHEMICAL SOCIETY REVIEWS, 2021, 第 2 作者
（20） TiO2/MXene-assisted LDI-MS for urine metabolic profiling in urinary disease, Advanced Functional Materials, 2021, 
（21） Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry (vol 10, pg 10958, 2019), CHEMICAL SCIENCE, 2020, 第 3 作者
（22） Ultrafast Photocatalytic Reaction Screening by Mass Spectrometry, ANALYTICAL CHEMISTRY, 2020, 第 3 作者
（23） Direct identification and metabolomic analysis of Huanglongbing associated with Candidatus Liberibacter spp. in navel orange by MALDI-TOF-MS, ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2020, 第 5 作者
（24） Enhancing surface-assisted laser desorption ionization mass spectrometry performance by integrating plasmonic hot-electron transfer effect through surface modification, CHEMICAL COMMUNICATIONS, 2019, 第 4 作者
（25） Mass, Size, and Density Measurements of Microparticles in a Quadrupole Ion Trap, ANALYTICAL CHEMISTRY, 2019, 第 2 作者
（26） 质谱成像在脑神经科学中的应用进展, Progress of Mass Spectrometry Imaging in Neuroscience, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 第 2 作者
（27） Ti3C2 MXene as a novel substrate provides rapid differentiation and quantitation of glycan isomers with LDI-MS, CHEMICAL COMMUNICATIONS, 2019, 第 4 作者
（28） 质谱成像在脑神经科学中的应用进展, Progress of Mass Spectrometry Imaging in Neuroscience, CHINESE JOURNAL OF ANALYTICAL CHEMISTRY, 2019, 第 2 作者
（29） Function of complement factor H and imaging of small molecules by MALDI-MSI in a methamphetamine behavioral sensitization model, BEHAVIOURAL BRAIN RESEARCH, 2019, 第 5 作者
（30） Laser cleavable probes for in situ multiplexed glycan detection by single cell mass spectrometry, CHEMICAL SCIENCE, 2019, 第 3 作者
（31） Utilizing a Mini-Humidifier To Deposit Matrix for MALDI Imaging, ANALYTICAL CHEMISTRY, 2018, 第 5 作者
（32） Ultratrace and robust visual sensor of Cd2+ ions based on the size-dependent optical properties of Au@g-CNQDs nanoparticles in mice models, BIOSENSORS & BIOELECTRONICS, 2018, 第 3 作者
（33） Ultratrace and robust visual sensor of Cd2+ ions based on the size-dependent optical properties of Au@g-CNQDs nanoparticles in mice models, BIOSENSORS AND BIOELECTRONICS, 2018, 第 3 作者
（34） Laser Cleavable Probes-Based Cell Surface Engineering for in Situ Sialoglycoconjugates Profiling by Laser Desorption/lonization Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 2 作者
（35） N-Phenyl-2-naphthylamine as a Novel MALDI Matrix for Analysis and in Situ Imaging of Small Molecules, ANALYTICAL CHEMISTRY, 2018, 第 1 作者
（36） Mass spectrometry imaging of the in situ drug release from nanocarriers, SCIENCE ADVANCES, 2018, 第 2 作者
（37） The metabolism and distribution of imidazole alkaloids from Lepidium meyenii (Maca) in mouse by matrix-assisted laser desorption/ionization mass spectrometry imaging, INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2018, 第 2 作者
（38） Differentiation and Relative Quantitation of Disaccharide Isomers by MALDI-TOF/TOF Mass Spectrometry, ANALYTICAL CHEMISTRY, 2018, 第 4 作者
（39） Characterization of organic aerosol in Beijing by laser desorption ionization coupled with Fourier Transform Ion Cyclotron Resonance Mass spectrometry, ATMOSPHERIC ENVIRONMENT, 2017, 第 5 作者
（40） (S)-Oxiracetam is the Active Ingredient in Oxiracetam that Alleviates the Cognitive Impairment Induced by Chronic Cerebral Hypoperfusion in Rats, SCIENTIFICREPORTS, 2017, 第 2 作者
（41） Effects of Dl-3-n-butylphthalide on Cerebral Ischemia Infarction in Rat Model by Mass Spectrometry Imaging, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 第 6 作者
（42） Mass Spectrometry Imaging of Kidney Tissue Sections of Rat Subjected to Unilateral Ureteral Obstruction, SCIENTIFIC REPORTS, 2017, 第 1 作者
（43） Hexagonal boron nitride nanosheets as a multifunctional background-free matrix to detect small molecules and complicated samples by MALDI mass spectrometry, CHEMICAL COMMUNICATIONS, 2017, 第 4 作者
（44） Application of flowerlike MgO for highly sensitive determination of lead via matrix-assisted laser desorption/ionization mass spectrometry, RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2016, 第 4 作者
（45） Rapidly Probing Antibacterial Activity of Graphene Oxide by Mass Spectrometry-based Metabolite Fingerprinting., SCIENTIFIC REPORTS, 2016, 第 5 作者
（46） Fluorographene nanosheets: a new carbon-based matrix for the detection of small molecules by MALDI-TOF MS, RSC ADVANCES, 2016, 第 3 作者
（47） The bridge between thin layer chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry: The realization of liquid thin layer chromatography-mass spectrometry, JOURNAL OF CHROMATOGRAPHY A, 2016, 第 7 作者
（48） 小分子物质的MALDI分析及质谱成像研究进展, Review of matrix-assisted laser desorption/ionization mass spectrometry in analysis and imaging of small molecules, 中国科学 : 化学, 2016, 第 5 作者
（49） The bridge between thin layer chromatography-mass spectrometry and high-performance liquid chromatography-mass spectrometry: The realization of liquid thin layer chromatography-mass spectrometry (LTLC-MS), JOURNAL OF CHROMATOGRAPHY A, 2016, 第 7 作者
（50） In Situ Bioconjugation and Ambient Surface Modification Using Reactive Charged Droplets, ANALYTICAL CHEMISTRY, 2015, 第 5 作者
（51） MALDI-TOF MS Imaging of Metabolites with a N-(1-Naphthyl) Ethylenediamine Dihydrochloride Matrix and Its Application to Colorectal Cancer Liver Metastasis, ANALYTICALCHEMISTRY, 2015, 第 5 作者
（52） Mass spectrometry imaging reveals the sub-organ distribution of carbon nanomaterials, Nature Nanotechnology, 2015, 第 3 作者
（53） Folic acid-polydopamine nanofibers show enhanced ordered-stacking via pi-pi interactions, SOFT MATTER, 2015, 第 5 作者
（54） 1,5-Diaminonaphthalene Hydrochloride Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Small Molecules in Tissues Following Focal Cerebral Ischemia, ANALYTICAL CHEMISTRY, 2014, 第 1 作者
（55） Ratiometric Fluorescent Probe Based on Gold Nanoclusters and Alizarin Red-Boronic Acid for Monitoring Glucose in Brain Microdialysate, ANALYTICAL CHEMISTRY, 2014, 第 3 作者
（56） Organic salt NEDC (N-naphthylethylenediamine dihydrochloride) assisted laser desorption ionization mass spectrometry for identification of metal ions in real samples, ANALYST, 2014, 第 4 作者
（57） Carbon Nanodots As a Matrix for the Analysis of Low-Molecular-Weight Molecules in Both Positive- and Negative-Ion Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Quantification of Glucose and Uric Acid in Real Samples, ANALYTICAL CHEMISTRY, 2013, 第 6 作者

   

（ 1 ） MALDI质谱分析用于自身免疫性疾病的快速诊断筛查, 负责人, 国家任务, 2023-01--2026-12