070703-海洋生物学

海岸带逆境生物学；贝类免疫学

2014-09--2017-06   中国科学院大学   博士
2011-09--2014-06   上海海洋大学   硕士
2007-09--2011-06   青岛农业大学   学士

   

2020-10~现在, 中国科学院烟台海岸带研究所, 副研究员
2017-07~2020-10,中国科学院烟台海岸带研究所, 助理研究员
2014-09~2017-06,中国科学院大学, 博士
2011-09~2014-06,上海海洋大学, 硕士
2007-09~2011-06,青岛农业大学, 学士

   

（ 1 ） 一种类似胞外陷阱的微网结构及其体外制备方法和应用, 2021, 第 1 作者, 专利号: CN113855786A

（ 2 ） 一株亚硝酸盐高效降解菌株及其应用, 2021, 第 1 作者, 专利号: CN113234648A

（ 3 ） 一种对虾益生菌及应用, 2021, 第 1 作者, 专利号: CN112980752A

（ 4 ） 一种用于预防细菌性疾病的菌株及应用, 2021, 第 1 作者, 专利号: CN112940998A

（ 5 ） 一种促进贝类幼虫附着变态菌株及应用, 2021, 第 1 作者, 专利号: CN112940997A

（ 6 ） 一种靶向抗菌基因、多肽、重组蛋白及其制备方法和应用, 2020, 第 1 作者, 专利号: CN111019951B

（ 7 ） 一种抗真菌基因、多肽、重组蛋白及其制备方法和应用, 2020, 第 1 作者, 专利号: CN111019952B

（ 8 ） 一株能够高效去除水体中有机质的菌株及其应用, 2020, 第 1 作者, 专利号: CN110643553B

（ 9 ） 一株能够高效去除水体中无机磷的菌株及其应用, 2020, 第 1 作者, 专利号: CN110643554B

（ 10 ） 一株氨氮高效降解菌株及其应用, 2020, 第 1 作者, 专利号: CN110791454A

（ 11 ） 一种贝类血细胞胞外陷阱的诱导方法及其应用, 2019, 第 1 作者, 专利号: CN110484503A

   

（1） Effects of dietary supplementation of Clostridium butyricum H129 on growth performance and intestinal health of turbot, Scophthalmus maximus, Aquaculture Reports, 2023, 
（2） In vitro study of deltamethrin-induced extracellular traps in hemocytes of Ruditapes philippinarum, Ecotoxicology and Environmental Safety, 2023, 
（3） 皱纹盘鲍稚鲍对海水酸化与溴氰菊酯复合胁迫的响应, Response of juvenile abalone of Haliotis discus hannai to the combined stress of ocean acidification and deltamethrin, 水产学报, 2022, 第 2 作者
（4） Effects of the potential probiotic Bacillus subtilis D1-2 on growth, digestion, immunity and intestinal flora in juvenile sea cucumber, Apostichopus japonicus, Fish and Shellfish Immunology, 2022, 
（5） A single-CRD C-type lectin from Haliotis discus hannai acts as pattern recognition receptor enhancing hemocytes opsonization, Fish and Shellfish Immunology, 2022, 
（6） Characteristic and antibacterial effect of a histone H2A and its preliminary roles in extracellular traps in manila clam Ruditapes philippinarum, Fish and Shellfish Immunology, 2022, 
（7） 14-3-3�� and 14-3-3�� are involved in innate immune responses in Pacific abalone (Haliotis discus hannai), Developmental and Comparative Immunology, 2021, 
（8） Antibacterial activity and mechanism of a type-I ubiquitin from the clam Ruditapes philippinarum, JOURNAL OF INVERTEBRATE PATHOLOGY, 2021, 第 3 作者  通讯作者
（9） Hemocyte extracellular traps of Manila clam Ruditapes philippinarum: Production characteristics and antibacterial effects, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 第 5 作者  通讯作者
（10） Mitochondria are essential for antibacterial extracellular trap formation mediated by zymosan in hemocytes of Ruditapes philippinarum, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2021, 第 4 作者  通讯作者
（11） Antimicrobial Defensin and DNA Traps in Manila Clam Ruditapes philippinarum: Implications for Their Roles in Immune Responses, Frontiers in Marine Science, 2021, 
（12） Identification, antibacterial activities and action mode of two macins from manila clam Venerupis philippinarum, Fish and Shellfish Immunology, 2021, 
（13） A fas apoptotic inhibitory molecule from Ruditapes philippinarum: Investigation on molecular characterization and functional analysis, FISH & SHELLFISH IMMUNOLOGY, 2020, 第 6 作者  通讯作者
（14） Molecular characterization, expression and immune functions of two C-type lectin from Venerupis philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2020, 第 12 作者  通讯作者
（15） Antibacterial activities and mechanisms of action of a defensin from manila clam Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2020, 第 3 作者  通讯作者
（16） 对虾生长不同阶段虾塘水体细菌和古菌的动态特征, The dynamics of bacteria and archaea in pond water associated with different growth phases of Penaeus vannamei, 生态学杂志, 2020, 第 4 作者
（17） A sialic acid-binding lectin with bactericidal and opsonic activities from Ruditapes philippinarum, FISH AND SHELLFISH IMMUNOLOGY, 2019, 第 6 作者
（18） Tissue distribution and functional characterization of mytimacin-4 in Mytilus galloprovincialis, JOURNAL OF INVERTEBRATE PATHOLOGY, 2019, 第 3 作者
（19） Two c-type lectins from Venerupis philippinarum: Possible roles in immune recognition and opsonization, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 8 作者  通讯作者
（20） Immune recognition, antimicrobial and opsonic activities mediated by a sialic acid binding lectin from Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 5 作者  通讯作者
（21） Seawater acidification increases copper toxicity: A multi-biomarker approach with a key marine invertebrate, the Pacific Oyster Crassostrea gigas, AQUATIC TOXICOLOGY, 2019, 第 6 作者
（22） A sialic acid-binding lectin with bactericidal and opsonic activities from Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 6 作者  通讯作者
（23） Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 9 作者  通讯作者
（24） A bactericidal permeability-increasing protein (BPI) from manila clam Ruditapes philippinarum: Investigation on the antibacterial activities and antibacterial action mode, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（25） Mannan oligosaccharide increases the growth performance, immunity and resistance capability against Vibro Parahemolyticus in juvenile abalone Haliotis discus hannai Ino, FISH AND SHELLFISH IMMUNOLOGY, 2019, 第 9 作者
（26） Molecular cloning and characterization of FADD from the manila clam Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 3 作者  通讯作者
（27） Two c-type lectins from Venerupis philippinarum: Possible roles in immune recognition and opsonization, FISH AND SHELLFISH IMMUNOLOGY, 2019, 第 8 作者
（28） A peptidoglycan recognition protein involved in immune recognition and immune defenses in Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（29） Scavenger receptor class B type I (SR-BI) in Ruditapes philippinarum: A versatile receptor with multiple functions, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（30） A macin identified from Venerupis philippinarum: Investigation on antibacterial activities and action mode, FISH & SHELLFISH IMMUNOLOGY, 2019, 第 1 作者
（31） The role of GST omega in metabolism and detoxification of arsenic in clam Ruditapes philippinarum, AQUATIC TOXICOLOGY, 2018, 第 7 作者
（32） The impact of ocean acidification and cadmium on the immune responses of Pacific oyster, Crassostrea gigas, FISH & SHELLFISH IMMUNOLOGY, 2018, 第 5 作者
（33） CO2-induced ocean acidification impairs the immune function of the Pacific oyster against Vibrio splendidus challenge: An integrated study from a cellular and proteomic perspective, SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 第 3 作者
（34） Peptidoglycan recognition protein of Solen grandis (SgPGRP-S1) mediates immune recognition and bacteria clearance, FISH & SHELLFISH IMMUNOLOGY, 2018, 第 2 作者
（35） Seawater Acidification Reduced the Resistance of Crassostrea gigas to Vibrio splendidus Challenge: An Energy Metabolism Perspective, FRONTIERS IN PHYSIOLOGY, 2018, 第 4 作者
（36） Seawater acidification aggravated cadmium toxicity in the oyster Crassostrea gigas: Metal bioaccumulation, subcellular distribution and multiple physiological responses, SCIENCE OF THE TOTAL ENVIRONMENT, 2018, 第 5 作者
（37） Integrative Biomarker Assessment of the Influence of Saxitoxin on Marine Bivalves: A Comparative Study of the Two Bivalve Species Oysters, Crassostrea gigas, and Scallops, Chlamys farreri, FRONTIERS IN PHYSIOLOGY, 2018, 第 5 作者
（38） Two macrophage migration inhibitory factors (MIFs) from the clam Ruditapes philippinarum: Molecular characterization, localization and enzymatic activities, FISH & SHELLFISH IMMUNOLOGY, 2018, 第 2 作者
（39） A defensin-like antimicrobial peptide from the manila clam Ruditapes philippinarum: Investigation of the antibacterial activities and mode of action, FISH & SHELLFISH IMMUNOLOGY, 2018, 第 1 作者
（40） Molecular characterization, expression and functional analysis of two Kazal-type serine protease inhibitors from Venerupis philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2017, 第 2 作者
（41） 菲律宾蛤仔免疫效应因子的多样性和免疫功能研究, 2017, 第 1 作者
（42） Molecular characterization, expression and antimicrobial activities of two c-type lysozymes from manila clam Venerupis philippinarum, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2017, 第 1 作者
（43） Individual and Combined Toxicities of Benzoapyrene and 2,2',4,4'-Tetrabromodiphenyl Ether on Early Life Stages of the Pacific Oyster, Crassostrea gigas, BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, 2017, 第 2 作者
（44） Cd2+和Pb2+单一与复合污染对脊尾白虾的急性毒性效应研究, Single and joint acute toxic effects of cadmium and lead onPalaemon carincauda, 海洋科学, 2017, 第 4 作者
（45） Molecular characterization and antibacterial activity of a phage-type lysozyme from the Manila clam, Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2017, 第 1 作者
（46） Corrigendum to "An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas" Mar. Pollut. Bull. 112 (1���2) (15 November 2016) 318���326, MARINE POLLUTION BULLETIN, 2016, 第 6 作者
（47） An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas, MARINE POLLUTION BULLETIN, 2016, 第 6 作者
（48） An integrative biomarker approach to assess the environmental stress in the north coast of Shandong Peninsula using native oysters, Crassostrea gigas (vol 112, pg 318, 2016), MARINE POLLUTION BULLETIN, 2016, 第 6 作者
（49） Molecular diversity and evolution of defensins in the manila clam Ruditapes philippinarum, FISH & SHELLFISH IMMUNOLOGY, 2015, 第 3 作者
（50） A defensin from clam Venerupis philippinarum : Molecular characterization, localization, antibacterial activity, and mechanism of action, DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2015, 第 2 作者
（51） 大竹蛏（Solen grandis）铁蛋白基因的克隆及其在转录水平上对微生物多糖的应答, 海洋与湖沼, 2013, 第 1 作者

   

（ 1 ） 西沙群岛中光层珊瑚共生总体组成与遗传多样性, 负责人, 国家任务, 2022-12--2026-12
（ 2 ） 菲律宾蛤仔mTOR分子对胞外陷阱发生的调控作用及机制研究, 负责人, 国家任务, 2022-01--2025-12
（ 3 ） 中国科学院青年创新促进会人才项目, 负责人, 中国科学院计划, 2022-01--2025-12
（ 4 ） 高效渔业投入品关键技术研究, 负责人, 境内委托项目, 2020-08--2025-08