基本信息
豆晓阳 女 中国科学院分子细胞科学卓越创新中心
电子邮件: xiaoyang.dou@sibcb.ac.cn
通信地址: 上海市岳阳路320号生化大楼
邮政编码:
电子邮件: xiaoyang.dou@sibcb.ac.cn
通信地址: 上海市岳阳路320号生化大楼
邮政编码:
招生信息
招生专业
071010-生物化学与分子生物学
招生方向
RNA修饰与染色质调控
教育背景
2011-09--2018-06 中国科学院大学 博士2007-09--2011-07 河北经贸大学 学士
工作经历
工作简历
2018-12~2024-06,芝加哥大学, 博士后2011-09~2018-06,中国科学院大学, 博士2007-09~2011-07,河北经贸大学, 学士
出版信息
发表论文
(1) Chemical manipulation of m1A mediates its detection in human tRNA, RNA, 2024, 第 3 作者(2) Zebrafish Mbd5 binds to RNA m5C and regulates histone deubiquitylation and gene expression in development metabolism and behavior, Nucleic Acids Research, 2024, 第 3 作者(3) KARR-seq reveals cellular higher-order RNA structures and RNA���RNA interactions, Nature Biotechnology, 2024, 第 9 作者(4) Profiling of RNA-binding protein binding sites by in situ reverse transcription-based sequencing, Nature Methods, 2024, 第 5 作者(5) METTL14 is a chromatin regulator independent of its RNA N6-methyladenosine methyltransferase activity, Protein Cell, 2023, 第 1 作者(6) RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation, Nature Cell Biology, 2023, 第 1 作者(7) Globally reduced N6-methyladenosine (m6A) in C9ORF72-ALS/FTD dysregulates RNA metabolism and contributes to neurodegeneration, Nature neuroscience, 2023, 第 2 作者(8) Epitranscriptional regulation of TGF-�� pseudoreceptor BAMBI by m6A/YTHDF2 drives extrinsic radioresistance, Journal of Clinical Investigation, 2023, 第 5 作者(9) YTHDF2 inhibition potentiates radiotherapy antitumor efficacy, Cancer Cell, 2023, 第 2 作者(10) Dysregulation of the Epitranscriptomic Mark m1A in Ischemic Stroke, Translational Stroke Research, 2023, 第 3 作者(11) YTHDF2/m6A/NF�����B axis controls anti���tumor immunity by regulating intratumoral Tregs, The EMBO Journal, 2023, 第 2 作者(12) Quantitative sequencing using BID-seq uncovers abundant pseudouridines in mammalian mRNA at base resolution, Nature Biotechnology, 2023, 第 12 作者(13) Exon architecture controls mRNA m6A suppression and gene expression, Science, 2023, 第 3 作者(14) FTO mediates LINE1 m6A demethylation and chromatin regulation in mESCs and mouse development, Science, 2022, 第 7 作者(15) Nuclear m6A reader YTHDC1 regulates the scaffold function of LINE1 RNA in mouse ESCs and early embryos, Protein Cell, 2021, 第 7 作者(16) N6-deoxyadenosine methylation in mammalian mitochondrial DNA, Molecular cell, 2020, 第 6 作者(17) DNA 5-methylcytosine-specific amplification and sequencing, Journal of the American Chemical Society, 2020, 第 7 作者(18) N6-methyladenosine of chromosome-associated regulatory RNA regulates chromatin state and transcription, Science, 2020, 第 2 作者(19) The strand-biased mitochondrial DNA methylome and its regulation by DNMT3A, Genome Research, 2019, 第 1 作者(20) Impact of dietary interventions on noncoding RNA networks and mRNAs encoding chromatin-related factors, Cell reports, 2017, 第 3 作者(21) Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate, Nature communications, 2015, 第 2 作者(22) Integrating genomic, epigenomic, and transcriptomic features reveals modular signatures underlying poor prognosis in ovarian cancer, Cell reports, 2013, 第 6 作者
科研活动
科研项目
( 1 ) 启动经费, 负责人, 中国科学院计划, 2024-07--2030-07