基本信息
田野 女 硕导 中国科学院理化技术研究所
电子邮件: tiany@mail.ipc.ac.cn
通信地址: 北京市海淀区中关村东路29号
邮政编码:
电子邮件: tiany@mail.ipc.ac.cn
通信地址: 北京市海淀区中关村东路29号
邮政编码:
招生信息
招生专业
070305-高分子化学与物理0703J1-纳米科学与技术
招生方向
生物医用材料高分子自组装生物纳米材料
教育背景
2006-09--2011-07 中国科学院化学研究所 博士学位2002-09--2006-07 北京化工大学 学士学位
工作经历
工作简历
2017-08~现在, 中国科学院理化技术研究所, 副研究员2012-11~2017-08,中国科学院理化技术研究所, 助理研究员2011-09~2012-09,加拿大曼尼托巴大学, 博士后2006-09~2011-07,中国科学院化学研究所, 博士学位2002-09~2006-07,北京化工大学, 学士学位
专利与奖励
专利成果
( 1 ) 一种抗菌多肽修饰的蛋白衍生物及其制备方法和应用, 2022, 第 3 作者, 专利号: CN115232193A( 2 ) 烟草花叶病毒在刺激巨噬细胞极化为M1型巨噬细胞中应用, 2022, 第 3 作者, 专利号: CN114480280A( 3 ) 多糖多肽偶联物在治疗感染性角膜炎中的用途, 2022, 第 5 作者, 专利号: CN113577302B( 4 ) 一种壳聚糖-抗菌性多肽接枝聚合物及其制备方法和应用, 2021, 第 3 作者, 专利号: CN111484568B( 5 ) 一种蛋白质组装体及其制备方法, 2020, 第 3 作者, 专利号: CN108640980B( 6 ) 一种噬菌体及其在制备灭活细菌的光动力制剂中的应用, 2019, 第 2 作者, 专利号: CN110151994A( 7 ) 一种纳米粒子及其在制备灭活细菌的光动力制剂中的应用, 2019, 第 3 作者, 专利号: CN110075089A( 8 ) 用于水中除砷的纤维素基/Fe 3 O 4 复合吸附材料及其制备方法, 2012, 第 3 作者, 专利号: CN102476043A( 9 ) 用于去除水中重金属阳离子的纤维素基吸附材料及其制法, 2012, 第 3 作者, 专利号: CN102476044A( 10 ) 用于去除水中砷和氟离子的纤维素基吸附材料及其制备方法, 2011, 第 4 作者, 专利号: CN102139202A
出版信息
发表论文
(1) Histatin 5-Inspired Short-Chain Peptides Selectively Combating Pathogenic Fungi with Multifaceted Mechanisms, ADVANCED HEALTHCARE MATERIALS, 2024, 第 9 作者(2) Programming of Macrophage Polarization in Different Stages for Accelerating Wound Healing, CHEMICAL ENGINEERING JOURNAL, 2024, 第 4 作者(3) In Situ Formed Antibacterial Hydrogel with Collagenase-Responsive Activity for Prevention of MRSA-Induced Osteomyelitis, CHEMICAL ENGINEERING JOURNAL, 2024, 第 10 作者 通讯作者(4) One-Dimensional Rod-like Tobacco Mosaic Virus Promotes Macrophage Polarization for a Tumor-Suppressive Microenvironment, NANO LETTERS, 2023, 第 11 作者 通讯作者(5) Guanidinylated/PEGylated chitosan in the bioink promotes the formation of multi-layered keratinocytes in a human skin equivalent, Carbohydrate Polymers, 2023, 第 5 作者(6) Overcoming the Stromal Barrier ofthe Cornea with a Peptide Conjugate Nano-Assembly to Combat Fungal Keratitis, ADVANCED HEALTHCARE MATERIALS, 2023, 第 4 作者(7) Surface decoration with leucine tetrapeptide: An antibacterial strategy against Gram-negative bacteria, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2023, 第 11 作者 通讯作者(8) 水溶性壳聚糖水凝胶对糖尿病小鼠感染全层皮肤缺损创面的作用及其机制, Effects and mechanism of water-soluble chitosan hydrogel on infected full-thickness skin defect wounds in diabetic mice, 中华烧伤与创面修复杂志, 2022, 第 8 作者(9) Conjugating Peptides onto 1D Rodlike Bionanoparticles for Enhanced Activity against Gram-Negative Bacteria, NANO LETTERS, 2021, 第 8 作者 通讯作者(10) A biomimetic orthogonal-bilayer tubular scaffold for the co-culture of endothelial cells and smooth muscle cells, RSC ADVANCES, 2021, 第 5 作者(11) Conjugating Peptides onto 1D Rodlike Bionanoparticles for Enhanced Activity against Gram-Negative Bacteria, NANOLETTERS, 2021, 第 8 作者 通讯作者(12) Single-wavelength Excited Ratiometric Fluorescence pH Probe to Image Intracellular Trafficking of Tobacco Mosaic Virus, Single-wavelength Excited Ratiometric Fluorescence pH Probe to Image Intracellular Trafficking of Tobacco Mosaic Virus, CHINESE JOURNAL OF POLYMER SCIENCE, 2020, 第 8 作者 通讯作者(13) Combating Pseudomonas aeruginosa Biofilms by a Chitosan-PEG-Peptide Conjugate via Changes in Assembled Structure, ACS APPLIED MATERIALS & INTERFACES, 2020, 第 12 作者 通讯作者(14) 3D-printable supramolecular hydrogels with shear-thinning property: fabricating strength tunable bioink via dual crosslinking, 3D-printable supramolecular hydrogels with shear-thinning property: fabricating strength tunable bioink via dual crosslinking, BIOACTIVE MATERIALS, 2020, 第 5 作者(15) Phenotype Regulation of Smooth Muscle Cells Through Facial Crystallization of Poly(epsilon-Caprolactone), JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2019, 第 5 作者 通讯作者(16) Membrane intercalation-enhanced photodynamic inactivation of bacteria by a metallacycle and TAT-decorated virus coat protein, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019, 第 7 作者 通讯作者(17) Fluorous interaction induced self-assembly of tobacco mosaic virus coat protein for cisplatin delivery, NANOSCALE, 2018, 第 6 作者 通讯作者(18) Balancing antimicrobial activity with biological safety: bifunctional chitosan derivative for the repair of wounds with Gram-positive bacterial infections, JOURNAL OF MATERIALS CHEMISTRY B, 2018, 第 4 作者(19) Integration of Cell-Penetrating Peptides with Rod-like Bionanoparticles: Virus-Inspired Gene-Silencing Technology, NANO LETTERS, 2018, 第 1 作者(20) Filamentous Virus Oriented Pyrene Excimer Emission and Its Efficient Energy Transfer, JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2018, 第 3 作者(21) Luminescent supramolecular polymer nanoparticles for ratiometric hypoxia sensing, imaging and therapy, MATERIALS CHEMISTRY FRONTIERS, 2018, 第 2 作者(22) Programming Self-Assembly of Tobacco Mosaic Virus Coat Proteins at Pickering Emulsion Interfaces for Nanorod-Constructed Capsules, ACS APPLIED MATERIALS & INTERFACES, 2017, 第 4 作者 通讯作者(23) Mussel-Inspired Polydopamine Coating on Tobacco Mosaic Virus: One-Dimensional Hybrid Nanofibers for Gold Nanoparticle Growth, LANGMUIR, 2017, 第 3 作者 通讯作者(24) One-Pot Green Synthesis of Nitrogen-Doped Carbon Quantum Dots for Cell Nucleus Labeling and Copper(II) Detection, CHEMISTRY-AN ASIAN JOURNAL, 2017, 第 2 作者(25) 烟草花叶病毒的特定位点改性及应用, Site-specific Modification of Tobacco Mosaic Virus and Its Applications, 影像科学与光化学, 2017, 第 1 作者(26) Glyco-decorated tobacco mosaic virus as a vector for cisplatin delivery, JOURNAL OF MATERIALS CHEMISTRY B, 2017, 第 5 作者 通讯作者(27) Rod-like plant virus: Functionalization, self-assembly, and bioapplications, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2016, 第 2 作者(28) Tobacco Mosaic Virus-Based 1D Nanorod-Drug Carrier via the Integrin-Mediated Endocytosis Pathway, ACS APPLIED MATERIALS & INTERFACES, 2016, 第 1 作者(29) Conjugated oligomer-based nanocarrier for chemotherapy agents delivery, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2016, 第 2 作者(30) Size Dependent Cellular Uptake of Rod-like Bionanoparticles with Different Aspect Ratios, SCIENTIFIC REPORTS, 2016, 第 3 作者(31) Hierarchical Self-Assembly of Responsive Organoplatinum(II) Metallacycle-TMV Complexes with Turn-On Fluorescence, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2016, 第 1 作者(32) Multifunctional self-assembled polymeric nanoprobes for FRET-based ratiometric detection of mitochondrial H2O2 in living cells, CHEMICAL COMMUNICATIONS, 2015, 第 3 作者(33) Light- and pH-activated intracellular drug release from polymeric mesoporous silica nanoparticles, COLLOIDS AND SURFACES B-BIOINTERFACES, 2015, 第 1 作者(34) Probing the Endocytic Pathways of the Filamentous Bacteriophage in Live Cells Using Ratiometric pH Fluorescent Indicator, ADVANCED HEALTHCARE MATERIALS, 2015, 第 1 作者(35) Confined chromophores in tobacco mosaic virus to mimic green fluorescent protein, CHEMICAL COMMUNICATIONS, 2015, 第 4 作者(36) Preparation of Polyethylene Polyamine-modified Cellulose and Its Adsorbability for As, F and Cr Anions, ACTA POLYMERICA SINICA, 2014, 第 4 作者(37) 多乙烯多胺改性纤维素及其对水中砷、氟、铬吸附性能研究, Preparation of Polyethylene Polyamine-modified Cellulose and Its Adsorbability for As,F and Cr Anions, ACTA POLYMERICA SINICA, 2014, 第 4 作者(38) Electrospun Tubular Scaffold with Circumferentially Aligned Nanofibers for Regulating Smooth Muscle Cell Growth, ACS APPLIED MATERIALS & INTERFACES, 2014, 第 4 作者(39) Bioactive Nanoparticle-Gelatin Composite Scaffold with Mechanical Performance Comparable to Cancellous Bones, ACS APPLIED MATERIALS & INTERFACES, 2014, 第 3 作者(40) Polymeric Supra-amphiphiles Based on Terminal Group Electrostatic Interactions: Fabrication of Micelles with Modifiable Surfaces, LANGMUIR, 2014, 第 3 作者(41) Hetero-epitaxy of anisotropic polycaprolactone films for the guidance of smooth muscle cell growth, CHEMICAL COMMUNICATIONS, 2013, 第 7 作者(42) Edge-modified amphiphilic Laponite nano-discs for stabilizing Pickering emulsions, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2013, 第 5 作者(43) Polymeric mesoporous silica nanoparticles as a pH-responsive switch to control doxorubicin intracellular delivery, JOURNAL OF MATERIALS CHEMISTRY B, 2013, 第 1 作者(44) 纤维素基吸附剂——绿色、经济的水处理材料, CELLULOSE BASED ADSORBENTS ������GREEN AND LOW-COST MATERIALS FOR WATER TREATMENT, 环境化学, 2011, 第 1 作者(45) Modified native cellulose fibers���A novel efficient adsorbent for both fluoride and arsenic, JOURNAL OF HAZARDOUS MATERIALS, 2011, 第 1 作者(46) 纳米磁种材料表面改性及其水吸附性能, Surface Modification of Nano Magnetic Seeds and the Aqueous Absorbing Properties, 科技导报, 2011, 第 2 作者(47) Improving the blood clearance time of I-125 labeled Dex-g-PMAGGCONHTyr by copolymerization, POLYMER CHEMISTRY, 2011, 第 6 作者(48) Synthesis of magnetic wheat straw for arsenic adsorption, JOURNAL OF HAZARDOUS MATERIALS, 2011, 第 1 作者(49) Anisotropic oxygen plasma etching of colloidal particles in electrospun fibers, CHEMICAL COMMUNICATIONS, 2011, 第 2 作者(50) 纳米磁种材料表面改性及其水吸附性能, Surface Modification of Nano Magnetic Seeds and the Aqueous Absorbing Properties, 科技导报, 2011, 第 2 作者(51) Controllable Aggregation and Reversible pH Sensitivity of AuNPs Regulated by Carboxymethyl Cellulose, LANGMUIR, 2010, 第 5 作者(52) 天然纤维素纤维改性及其对水中砷的吸附, Modification of Natural Cellulose Fibers for Arsenic Adsorption from Water, 科技导报, 2010, 第 1 作者(53) Tailoring nanowire network morphology and charge carrier mobility of poly(3-hexylthiophene)/c-60 films, JOURNAL OF PHYSICAL CHEMISTRY C, 2009, 第 8 作者
科研活动
科研项目
( 1 ) 基于棒状植物病毒的多糖结合疫苗用于预防细菌/真菌感染研究, 负责人, 国家任务, 2023-01--2026-12( 2 ) 针对细菌/真菌感染的植物病毒基疫苗, 负责人, 研究所自主部署, 2022-05--2025-04( 3 ) 基于多功能化生物纳米粒子/血小板复合体的RNA干扰系统用于纤维化抑制研究, 负责人, 国家任务, 2020-01--2023-12( 4 ) 氟尾/细胞穿膜肽双修饰蛋白的自组装及构建仿病毒基因载体, 负责人, 地方任务, 2018-01--2020-12( 5 ) 基于生物材料构建的微环境诱导多种损伤组织同步修复再生的基础科学问题与关键技术研究, 参与, 国家任务, 2017-07--2020-12( 6 ) 中国科学院青年创新促进会, 负责人, 其他国际合作项目, 2017-01--2020-12( 7 ) 基于规整蛋白组装体的靶向抗肿瘤药物载体的研究, 负责人, 国家任务, 2014-01--2016-12( 8 ) 基于棒状或盘状蛋白组装体的化疗药物载体, 负责人, 研究所自主部署, 2013-07--2015-06
参与会议
(1)烟草花叶病毒衣壳蛋白的程序式自组装构建稳定的皮克林乳液 中国科协第316次青年科学家论坛 2017-09-14(2)一维棒状病毒的自组装 第一届能源化学与材料国际青年论坛暨中科院青促会化材分会2017学术年会 2017-05-02(3)Self-assembly of 1D Rod-like Virus with TPE-based Discrete Organoplatinum(II) Metallacycles “glue” via Electrostatic Interactions 第十二届国际高分子物理学术讨论会 2016-06-10