1007J6-再生医学
100101-人体解剖与组织胚胎学
100203-老年医学

干细胞
代谢组学
再生医学

2009-09--2013-11   哈佛大学 Harvard University   Ph.D.
2005-08--2008-05   普林斯顿大学 Princeton University   B.A.

现代组织胚胎学及其技术应用 Current Histology and Embryology and Technologies
Stem Cells & Regenerative Medicine

   

（1） HHMI International Research Scholar, 特等奖, 其他, 2018

[1] 黄仕强. 质谱技术在鉴定肌肉生物标志物的用途. 2023100721659, 2023-01-13.
[2] 黄仕强. D族维生素及其代谢物用于真核动物细胞核糖体激动剂的用途. CN2023100071595, 2023-01-04.
[3] 黄仕强. 棕榈酰肉碱的制药用途. CN2022113736643, 2022-11-03.
[4] 黄仕强. 皮质激素的制药用途. CN2022113707903, 2022-11-03.
[5] 黄仕强. 年轻化骨骼肌肉细胞及其制备方法和应用. CN2021111992617, 2021-11-11.
[6] 黄仕强. 年轻化骨骼肌肉细胞及其制备方法和应用. 2021111992617, 2021-11-01.
[7] 黄仕强. 非多能性细胞及其制备方法和应用. 2021111992458, 2021-11-01.
[8] 黄仕强. 维生素代谢物用于真核动物细胞核糖体激动剂的用途. 2021100090017, 2021-10-01.
[9] 黄仕强. Methods and compositions for tissue regeneration. PCT/CN2020/115635, 2020-01-01.
[10] 黄仕强. 用于对抗代谢疾病的组合物及其用途. PCT/CN2020/112143, 2020-01-01.
[11] 黄仕强. Compositions and use of engineered myogenic cells. PCT/CN2020/092615, 2020-01-01.
[12] 黄仕强. Methods and compositions for muscle regeneration. PCT/CN2019/105890, 2019-01-01.
[13] 黄仕强. Methods and compositions for the metabolic syndrome. PCT/CN2019/103677, 2019-01-01.
[14] 黄仕强. Compositions and use of engineered myogenic cells. PCT/CN2019/088977, 2019-01-01.
[15] 黄仕强. Methods and compositions for efficient differentiation of skeletal muscle progenitor cells into myofibers during muscle regeneration. PCT/SG10201501387X, 2015-01-01.
[16] 黄仕强. Mix of inhibitors of Glycine metabolism that eliminate human pluripotent stem cells. PCT/SG10201404767Q, 2014-01-01.

   

[1] 黄仕强. Spatial metabolomics reveals skeletal myofiber subtypes. Sci Adv[J]. 2023, 第 1 作者
[2] 黄仕强. Adult progenitor rejuvenation with embryonic factor. Cell Prolif[J]. 2023, 第 1 作者
[3] 黄仕强. Muscle Injuries Induce a Prostacyclin-PPARγ/PGC1a-FAO Spike That Boosts Regeneration. Adv Sci (Weinh)[J]. 2023, 第 1 作者
[4] 黄仕强. XAI-enabled neural network analysis of metabolite spatial distributions. Anal Bioanal Chem[J]. 2023, 第 1 作者
[5] Fan, Tingting, Wang, Shuo, Jiang, Zongmin, Ji, Shen, Cao, Wenhua, Liu, Wenli, Ji, Yun, Li, Yujing, ShyhChang, Ng, Gu, Qi. Controllable assembly of skeletal muscle-like bundles through 3D bioprinting. BIOFABRICATION[J]. 2022, 第 9 作者  通讯作者  14(1): 
[6] Zongmin Jiang, Liping Zhang, Ziyue Yao, Wenhua Cao, Shilin Ma, Yu Chen, Lu Guang, Zipeng Zheng, Chunwei Li, Kang Yu, Ng ShyhChang. Machine learning‐based phenotypic screening for postmitotic growth inducers uncover vitamin D3 metabolites as small molecule ribosome agonists. CELL PROLIFERATION[J]. 2022, 第 11 作者  通讯作者  55(5): 
[7] Ma, Shilin, ShyhChang, Ng. The Metabaging Cycle. CELL PROLIFERATION. 2022, 第 2 作者  通讯作者  55(3): http://dx.doi.org/10.1111/cpr.13197.
[8] Zunpeng Liu, Wei Li, Lingling Geng, Liang Sun, Qiaoran Wang, Yang Yu, Pengze Yan, Chuqian Liang, Jie Ren, Moshi Song, Qian Zhao, Jinghui Lei, Yusheng Cai, Jiaming Li, Kaowen Yan, Zeming Wu, Qun Chu, Jingyi Li, Si Wang, Chunyi Li, JingDong J Han, Reyna HernandezBenitez, Ng ShyhChang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, GuangHui Liu. Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor. CELL DISCOVERY[J]. 2022, 第 23 作者8: 
[9] Wang, Renying, Zhang, Peijing, Wang, Jingjing, Ma, Lifeng, Weigao, E, Suo, Shengbao, Jiang, Mengmeng, Li, Jiaqi, Chen, Haide, Sun, Huiyu, Fei, Lijiang, Zhou, Ziming, Zhou, Yincong, Chen, Yao, Zhang, Weiqi, Wang, Xinru, Mei, Yuqing, Sun, Zhongyi, Yu, Chengxuan, Shao, Jikai, Fu, Yuting, Xiao, Yanyu, Ye, Fang, Fang, Xing, Wu, Hanyu, Guo, Qile, Fang, Xiunan, Li, Xia, Gao, Xianzhi, Wang, Dan, Xu, PengFei, Zeng, Rui, Xu, Gang, Zhu, Lijun, Wang, Lie, Qu, Jing, Zhang, Dan, Ouyang, Hongwei, Huang, He, Chen, Ming, Ng, ShyhChang, Liu, GuangHui, Yuan, GuoCheng, Guo, Guoji, Han, Xiaoping. Construction of a cross-species cell landscape at single-cell level. NUCLEIC ACIDS RESEARCH. 2022, 第 41 作者  通讯作者  51(2): 501-516, http://dx.doi.org/10.1093/nar/gkac633.
[10] Song, Dan, ShyhChang, Ng. An RNA methylation code to regulate protein translation and cell fate. CELL PROLIFERATION[J]. 2022, 第 2 作者  通讯作者  55(5): http://dx.doi.org/10.1111/cpr.13224.
[11] Chunwei Li, Kang Yu, Ng ShyhChang, Zongmin Jiang, Taoyan Liu, Shilin Ma, Lanfang Luo, Lu Guang, Kun Liang, Wenwu Ma, Hefan Miao, Wenhua Cao, Ruirui Liu, Lingjuan Jiang, Songlin Yu, Chao Li, Huijun Liu, Longyu Xu, Rongji Liu, Xinyuan Zhang, Gaoshan Liu. Pathogenesis of sarcopenia and the relationship with fat mass: descriptive review. JOURNAL OF CACHEXIA, SARCOPENIA AND MUSCLE[J]. 2022, 第 3 作者  通讯作者  13(2): 781-794, 
[12] Liang, Lingmin, Tian, Yao, Feng, Lin, Wang, Chaoqun, Feng, Guihai, Stacey, Glyn Nigel, ShyhChang, Ng, Wu, Jun, Hu, Baoyang, Li, Wei, Hao, Jie, Wang, Liu, Wang, Yukai. Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs. STEM CELL RESEARCH & THERAPY[J]. 2022, 第 7 作者13(1): http://dx.doi.org/10.1186/s13287-022-03104-7.
[13] Cao, Jiani, Stacey, Glyn, ShyhChang, Ng, Zhao, Tongbiao. Developing standards to support cell technology applications. CELL PROLIFERATION. 2022, 第 3 作者55(4): http://dx.doi.org/10.1111/cpr.13210.
[14] Chew, Elaine G Y, Lim, Tze Chiun, Leong, Meng Fatt, Liu, Xingliang, Sia, Yee Yen, Leong, See Ting, YanJiang, Benjamin C, Stoecklin, Celine, Borhan, Rosa, HeilmannHeimbach, Stefanie, Nothen, Markus M, Viasnoff, Virgile, ShyhChang, Ng, Wan, Andrew C A, Philpott, Michael P, Hillmer, Axel M. Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia. EXPERIMENTAL DERMATOLOGY[J]. 2022, 第 13 作者31(6): 906-917, http://dx.doi.org/10.1111/exd.14536.
[15] Li, ChunWei, Yu, Kang, ShyhChang, Ng, Li, GuoXun, Yu, SongLin, Liu, HuiJun, Yang, Bo, Li, ZiYao, Zhao, YongJie, Xu, LongYu, Xu, Jing, Jiang, LingJuan, Liu, RongJi, Zhang, XinYuan, Li, ShaoFei, Zhang, XiaoWei, Xie, HaiYan, Li, Kang, Zhan, YiXiang, Cui, Min, Tao, HangBo, Li, Yao, Liu, GaoShan, Ni, KeMin, Li, DongJing. Sterol metabolism and protein metabolism are differentially correlated with sarcopenia in Asian Chinese men and women. CELL PROLIFERATION[J]. 2021, 第 3 作者  通讯作者  54(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8016649/.
[16] ShyhChang, Ng, Li, Lei. Stabilizing Formative Pluripotent States with Germ Cell Competency. CELL STEM CELL[J]. 2021, 第 1 作者  通讯作者  28(3): 361-363, http://dx.doi.org/10.1016/j.stem.2021.02.021.
[17] Wang, Xiaoxiao, Xiang, Yunlong, Yu, Yang, Wang, Ran, Zhang, Yu, Xu, Qianhua, Sun, Hao, Zhao, ZhenAo, Jiang, Xiangxiang, Wang, Xiaoqing, Lu, Xukun, Qin, Dandan, Quan, Yujun, Zhang, Jiaqi, ShyhChang, Ng, Wang, Hongmei, Jing, Naihe, Xie, Wei, Li, Lei. Formative pluripotent stem cells show features of epiblast cells poised for gastrulation. CELL RESEARCH[J]. 2021, 第 15 作者31(5): 526-541, https://www.webofscience.com/wos/woscc/full-record/WOS:000619730300001.
[18] Liu, Tong Ming, Yildirim, Ege Deniz, Li, Pin, Fang, Hai Tong, Denslin, Vinitha, Kumar, Vibhor, Loh, Yuin Han, Lee, Eng Hin, Cool, Simon M, Teh, Bin Tean, Hui, James H, Lim, Bing, ShyhChang, Ng. Ascorbate and Iron Are Required for the Specification and Long-Term Self-Renewal of Human Skeletal Mesenchymal Stromal Cells. STEM CELL REPORTS[J]. 2020, 第 13 作者  通讯作者  14(2): 210-225, https://doaj.org/article/4d9d3e38c78343fd95dc58634ee62cac.
[19] Yao, Ziyue, Chen, Yu, Cao, Wenhua, ShyhChang, Ng. Chromatin-modifying drugs and metabolites in cell fate control. CELL PROLIFERATION. 2020, 第 4 作者  通讯作者  53(11): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7653270/.
[20] Xu, YaJie, Liu, PeiPei, Ng, ShyhChang, Teng, ZhaoQian, Liu, ChangMei. Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2020, 第 3 作者12(5): 327-336, http://lib.cqvip.com/Qikan/Article/Detail?id=7102219895.
[21] Wu, Jun, Song, Dingyun, Li, Zhongwen, Guo, Baojie, Xiao, Yani, Liu, Wenjing, Liang, Lingmin, Feng, Chunjing, Gao, Tingting, Chen, Yanxia, Li, Ying, Wang, Zai, Wen, Jianyan, Yang, Shengnan, Liu, Peipei, Wang, Lei, Wang, Yukai, Peng, Liang, Stacey, Glyn Nigel, Hu, Zheng, Feng, Guihai, Li, Wei, Huo, Yan, Jin, Ronghua, ShyhChang, Ng, Zhou, Qi, Wang, Liu, Hu, Baoyang, Dai, Huaping, Hao, Jie. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis. CELL RESEARCH[J]. 2020, 第 25 作者30(9): 794-809, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=6805741&detailType=1.
[22] ShyhChang Ng, Luo Liaofu. DNA Torsion-based Model of Cell Fate Phase Transitions. 2020, 第 1 作者http://arxiv.org/abs/2002.05942.
[23] Xu, Chang, Ooi, Wen Fong, Qamra, Aditi, Tan, Jing, Chua, Benjamin YanJiang, Ho, Shamaine Wei Ting, Das, Kakoli, Isa, Zul Fazreen Adam, Li, Zhimei, Yao, Xiaosai, Yan, Tingdong, Xing, Manjie, Huang, Kie Kyon, Lin, Joyce Suling, Nandi, Tannistha, Tay, Su Ting, Lee, Ming Hui, Tan, Angie Lay Keng, Ong, Xuewen, Ashktorab, Hassan, Smoot, Duane, Li, Shang, Ng, ShyhChang, Teh, Bin Tean, Tan, Patrick. HNF4 alpha pathway mapping identifies wild-type IDH1 as a targetable metabolic node in gastric cancer. GUT[J]. 2020, 第 23 作者69(2): 231-242, https://www.webofscience.com/wos/woscc/full-record/WOS:000508194700007.
[24] Liu, Taoyan, Ng ShyhChang. Oncofetal SALL4-Driven Tumorigenesis Is Highly Dependent on Oxidative Phosphorylation, Revealing Therapeutic Opportunities. GASTROENTEROLOGY. 2019, 第 2 作者  通讯作者  157(6): 1475-1477, http://dx.doi.org/10.1053/j.gastro.2019.09.044.
[25] Li, Chunwei, Yu, Kang, ShyhChang, Ng, Li, Guoxun, Jiang, Lingjuan, Yu, Songlin, Xu, Longyu, Liu, Rongji, Guo, Zijian, Xie, Haiyan, Li, Rongrong, Ying, Jie, Li, Kang, Li, Dongjing. Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention. JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE[J]. 2019, 第 3 作者  通讯作者  10(3): 586-600, https://www.webofscience.com/wos/woscc/full-record/WOS:000473093800010.
[26] Jiang, Zongmin, Guang, Lu, Li, Lei, Ng ShyhChang. Putting Stem Cells on a Low-Fat Diet Switches Their Pluripotent State. CELL STEM CELL. 2019, 第 4 作者  通讯作者  25(1): 3-5, 
[27] Chua, MinWen Jason, Yildirim, Ege Deniz, Tan, JunHao Elwin, Chua, YanJiang Benjamin, Low, SuetMei Crystal, Ding, Suet Lee Shirley, Li, Chunwei, Jiang, Zongmin, Teh, Bin Tean, Yu, Kang, ShyhChang, Ng. Assessment of different strategies for scalable production and proliferation of human myoblasts. CELL PROLIFERATION[J]. 2019, 第 11 作者  通讯作者  52(3): http://dx.doi.org/10.1111/cpr.12602.
[28] Zhang, Xing, Liu, Zunpeng, Liu, Xiaoqian, Wang, Si, Zhang, Yiyuan, He, Xiaojuan, Sun, Shuhui, Ma, Shuai, Ng ShyhChang, Liu, Feng, Wang, Qiang, Wang, Xiaoqun, Liu, Lin, Zhang, Weiqi, Song, Moshi, Liu, GuangHui, Qu, Jing. Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. Protein & Cell[J]. 2019, 第 9 作者10(9): 649-667, http://lib.cqvip.com/Qikan/Article/Detail?id=7002965332.
[29] Waqas Muhammad Usman, Tin Chanh Pham, Yuk Yan Kwok, Luyen Tien Vu, Victor Ma, Boya Peng, Yuen San Chan, Likun Wei, Siew Mei Chin, Ajijur Azad, Alex BaiLiang He, Anskar Y H Leung, Mengsu Yang, Ng ShyhChang, William C Cho, Jiahai Shi, Minh T N Le. Efficient RNA drug delivery using red blood cell extracellular vesicles. NATURE COMMUNICATIONS[J]. 2018, 第 14 作者9(1): https://doaj.org/article/2c042d1a154e4b878236c706ed430fe0.
[30] Lee, HoJoon, Jedrychowski, Mark P, Vinayagam, Arunachalam, Wu, Ning, ShyhChang, Ng, Hu, Yanhui, MinWen, Chua, Moore, Jodene K, Asara, John M, Lyssiotis, Costas A, Perrimon, Norbert, Gygi, Steven P, Cantley, Lewis C, Kirschner, Marc W. Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation. CELL REPORTS[J]. 2017, 第 5 作者20(3): 721-736, http://dx.doi.org/10.1016/j.celrep.2017.06.074.
[31] Andriani, Yosephine, Chua, Jason MinWen, Chua, Benjamin YanJiang, Phang, In Yee, ShyhChang, Ng, Tan, Wui Siew. Polyurethane acrylates as effective substrates for sustained in vitro culture of human myotubes. ACTA BIOMATERIALIA[J]. 2017, 第 5 作者  通讯作者  57: 115-126, http://dx.doi.org/10.1016/j.actbio.2017.04.022.
[32] Liu, Tong Ming, ShyhChang, Ng. SIRT2 and glycolytic enzyme acetylation in pluripotent stem cells. NATURE CELL BIOLOGY. 2017, 第 2 作者  通讯作者  19(5): 412-414, https://www.webofscience.com/wos/woscc/full-record/WOS:000400376100003.
[33] MinWen, Jason Chua, YanJiang, Benjamin Chua, Mishra, Srishti, Dai, Xiaoyun, Magae, Junji, ShyhChang, Ng, Kumar, Alan Prem, Sethi, Gautam, Donev, R. Molecular Targets of Ascochlorin and Its Derivatives for Cancer Therapy. STRESS AND INFLAMMATION IN DISORDERS. 2017, 第 11 作者108: 199-225, https://www.webofscience.com/wos/woscc/full-record/WOS:000405126100009.
[34] ShyhChang, Ng, Song, E, Hu, H. Metabolic Changes During Cancer Cachexia Pathogenesis. TRANSLATIONAL RESEARCH IN BREAST CANCER: BIOMARKER DIAGNOSIS, TARGETED THERAPIES AND APPROACHES TO PRECISION MEDICINE[J]. 2017, 第 1 作者1026: 233-249, https://www.webofscience.com/wos/woscc/full-record/WOS:000435991400012.
[35] ShyhChang, Ng, Ng, HuckHui. The metabolic programming of stem cells. GENES & DEVELOPMENT. 2017, 第 1 作者  通讯作者  31(4): 336-346, https://www.webofscience.com/wos/woscc/full-record/WOS:000396744700002.
[36] JunHao Elwin Tan, ShyhChang Ng, MinWen Jason Chua. Stem cell mitochondria during aging. SEMINARS IN CELL AND DEVELOPMENTAL BIOLOGY. 2016, 第 2 作者52: 110-118, http://dx.doi.org/10.1016/j.semcdb.2016.02.005.
[37] Zhang, Jin, Ratanasirintrawoot, Sutheera, Chandrasekaran, Sriram, Wu, Zhaoting, Ficarro, Scott B, Yu, Chunxiao, Ross, Christian A, Cacchiarelli, Davide, Xia, Qing, Seligson, Marc, Shinoda, Gen, Xie, Wen, Cahan, Patrick, Wang, Longfei, Ng, ShyhChang, Tintara, Supisara, Trapnell, Cole, Onder, Tamer, Loh, YuinHan, Mikkelsen, Tarjei, Sliz, Piotr, Teitell, Michael A, Asara, John M, Marto, Jarrod A, Li, Hu, Collins, James J, Daley, George Q. LIN28 Regulates Stem Cell Metabolism and Conversion to Primed Pluripotency. CELLSTEMCELL[J]. 2016, 第 15 作者19(1): 66-80, http://dx.doi.org/10.1016/j.stem.2016.05.009.
[38] Tan, Justin L, Fogley, Rachel D, Flynn, Ryan A, Ablain, Julien, Yang, Song, SaintAndre, Violaine, Fan, Zi Peng, Do, Brian T, Laga, Alvaro C, Fujinaga, Koh, Santoriello, Cristina, Greer, Celeste B, Kim, Yoon Jung, Clohessy, John G, Bothmer, Anne, Pandell, Nicole, Avagyan, Serine, Brogie, John E, van Rooijen, Ellen, Hagedorn, Elliott J, ShyhChang, Ng, White, Richard M, Price, David H, Pandolfi, Pier Paolo, Peterlin, B Matija, Zhou, Yi, Kim, Tae Hoon, Asara, John M, Chang, Howard Y, Young, Richard A, Zon, Leonard I. Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma. MOLECULAR CELL[J]. 2016, 第 21 作者62(1): 34-46, http://dx.doi.org/10.1016/j.molcel.2016.03.013.
[39] Elwin Tan Jun-Hao, Renuka Ravi Gupta, Ng Shyh-Chang. Lin28 and let-7 in the Metabolic Physiology of Aging. TRENDS IN ENDOCRINOLOGY & METABOLISM. 2016, 第 3 作者27(3): 132-141, http://dx.doi.org/10.1016/j.tem.2015.12.006.
[40] Fukawa, Tomoya, YanJiang, Benjamin Chua, MinWen, Jason Chua, JunHao, Elwin Tan, Huang, Dan, Qian, ChaoNan, Ong, Pauline, Li, Zhimei, Chen, Shuwen, Mak, Shi Ya, Lim, Wan Jun, Kanayama, Hiroomi, Mohan, Rosmin Elsa, Wang, Ruiqi Rachel, Lai, Jiunn Herng, Chua, Clarinda, Ong, Hock Soo, Tan, KerKan, Ho, Ying Swan, Tan, Iain Beehuat, Teh, Bin Tean, ShyhChang, Ng. Excessive fatty acid oxidation induces muscle atrophy in cancer cachexia. NATURE MEDICINE[J]. 2016, 第 22 作者  通讯作者  22(6): 666-+, https://www.webofscience.com/wos/woscc/full-record/WOS:000377476000024.
[41] MinWen, Jason Chua, JunHao, Elwin Tan, ShyhChang, Ng. Stem cell mitochondria during aging. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. 2016, 第 3 作者  通讯作者  52: 110-118, http://dx.doi.org/10.1016/j.semcdb.2016.02.005.
[42] Zhang, Wen Cai, Chin, Tan Min, Yang, Henry, Nga, Min En, Lunny, Declan Patrick, Lim, Edwin Kok Hao, Sun, Li Li, Pang, Yin Huei, Leow, Yi Ning, Malusay, Shanneen Rossellini Y, Lim, Priscilla Xin Hui, Lee, Jeravan Zili, Tan, Benedict Jian Wei, Ng ShyhChang, Lim, Elaine Hsuen, Lim, Wan Teck, Tan, Daniel Shao Weng, Tan, Eng Huat, Tai, Bee Choo, Soo, Ross Andrew, Tam, Wai Leong, Lim, Bing. Tumour-initiating cell-specific miR-1246 and miR-1290 expression converge to promote non-small cell lung cancer progression. NATURE COMMUNICATIONS[J]. 2016, 第 14 作者7(1): https://doaj.org/article/a77285cd13d847d6a9987229f6e39d6d.
[43] 黄仕强. Balancing Stem Cell Self-Renewal and Differentiation with PLZF.. STEMCELLS. 2016, 第 1 作者  通讯作者  
[44] Loh, Kyle M, Chen, Angela, Koh, Pang Wei, Deng, Tianda Z, Sinha, Rahul, Tsai, Jonathan M, Barkal, Amira A, Shen, Kimberle Y, Jain, Rajan, Morganti, Rachel M, ShyhChang, Ng, Fernhoff, Nathaniel B, George, Benson M, Wernig, Gerlinde, Salomon, Rachel E A, Chen, Zhenghao, Vogel, Hannes, Epstein, Jonathan A, Kundaje, Anshul, Talbot, William S, Beachy, Philip A, Ang, Lay Teng, Weissman, Irving L. Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types. CELL[J]. 2016, 第 11 作者166(2): 451-467, http://dx.doi.org/10.1016/j.cell.2016.06.011.
[45] Liu, Tong Ming, Lee, Eng Hin, Lim, Bing, ShyhChang, Ng. Concise Review: Balancing Stem Cell Self-Renewal and Differentiation with PLZF. STEM CELLS. 2016, 第 4 作者  通讯作者  34(2): 277-287, http://dx.doi.org/10.1002/stem.2270.
[46] ShyhChang, Ng, Daley, George Q. Metabolic Switches Linked to Pluripotency and Embryonic Stem Cell Differentiation. CELL METABOLISM. 2015, 第 1 作者21(3): 349-350, http://dx.doi.org/10.1016/j.cmet.2015.02.011.
[47] Wu, Linwei, Nguyen, Liem H, Zhou, Kejin, de Soysa, T Yvanka, Li, Lin, Miller, Jason B, Tian, Jianmin, Locker, Joseph, Zhang, Shuyuan, Shinoda, Gen, Seligson, Marc T, Zeitels, Lauren R, Acharya, Asha, Wang, Sam C, Mendell, Joshua T, He, Xiaoshun, Nishino, Jinsuke, Morrison, Sean J, Siegwart, Daniel J, Daley, Gerorge Q, ShyhChang, Ng, Zhu, Hao. Precise let-7 expression levels balance organ regeneration against tumor suppression. ELIFE[J]. 2015, 第 21 作者4: https://doaj.org/article/59dfff35532043c7a4356bb1fec531e8.
[48] Khaw, SweaLing, MinWen, Chua, Koh, ChengGee, Lim, Bing, ShyhChang, Ng. Oocyte Factors Suppress Mitochondrial Polynucleotide Phosphorylase to Remodel the Metabolome and Enhance Reprogramming. CELL REPORTS[J]. 2015, 第 5 作者12(7): 1080-1088, https://doaj.org/article/5218075313814fb4a989f1e631d6b1f9.
[49] ShyhChang, Ng, Zhu, Hao, de Soysa, T Yvanka, Shinoda, Gen, Seligson, Marc T, Tsanov, Kaloyan M, Liem Nguyen, Asara, John M, Cantley, Lewis C, Daley, George Q. Lin28 Enhances Tissue Repair by Reprogramming Cellular Metabolism. CELL[J]. 2013, 第 1 作者155(4): 778-792, http://dx.doi.org/10.1016/j.cell.2013.09.059.
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[51] ShyhChang, Ng, Daley, George Q. Lin28: Primal Regulator of Growth and Metabolism in Stem Cells. CELL STEM CELL. 2013, 第 1 作者12(4): 395-406, http://dx.doi.org/10.1016/j.stem.2013.03.005.
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[64] Lingmin Liang, Yao Tian, Lin Feng, Chaoqun Wang, Guihai Feng, Glyn Nigel Stacey, Ng Shyh-Chang, Jun Wu, Baoyang Hu, Wei Li, Jie Hao, Liu Wang, Yukai Wang. Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs. STEM CELL RESEARCH & THERAPY. 第 7 作者13(1): http://dx.doi.org/10.1186/s13287-022-03104-7.
[65] Zhang WCbrShyhChang NbrYang HbrRai AbrUmashankar SbrMa SMbrSoh BSbrSun LLbrTai BCbrNga MEbrBhakoo KKbrJayapal SRbrNichane MbrYu QbrAhmed DAbrTan CbrSing WPbrTam JbrThirugananam AbrNoghabi MSbrPang YHbrAng HSbrRobson PbrKaldis PbrSoo RAbrSwarup SbrLim EHbrLim B. Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis. CELL. 

   

（ 1 ） 自主布局课题, 主持, 市地级, 2017-01--2019-12
（ 2 ） ****启动经费, 主持, 国家级, 2017-12--2020-12
（ 3 ） 基于肌肉干细胞模型的肌肉衰减综合征研究, 主持, 部委级, 2017-01--2019-12
（ 4 ） HHMI-Gates International Research Scholar: Stem Cell Metabolism, 主持, 研究所（学校）, 2017-10--2022-12