071008-发育生物学

胚胎干细胞，多能性

2003-09--2006-07   北京大学   博士

   

干细胞生物学
胚胎工程

   

[1] Jiang, Liyuan, Wang, Xin, Wang, Leyun, Ma, Sinan, Ding, Yali, Liu, Chao, Wang, Siqi, Shao, Xuan, Zhang, Ying, Li, Zhikun, Li, Wei, Feng, Guihai, Zhou, Qi. Deciphering the placental abnormalities associated with somatic cell nuclear transfer at single-nucleus resolution. PROTEIN & CELL[J]. 2023, pwad030: http://dx.doi.org/10.1093/procel/pwad030.
[2] Sunyang Ying, Pengcheng Li, Jiaqiang Wang, Kaiqiong Chen, Yu Zou, Moyu Dai, Kai Xu, Guihai Feng, Changjian Zhang, Haiping Jiang, Wei Li, Ying Zhang, Qi Zhou. tRF-Gln-CTG-026 ameliorates liver injury by alleviating global protein synthesis. SIGNAL TRANSDUCTION AND TARGETED THERAPY[J]. 2023, 8(1): 144-, http://dx.doi.org/10.1038/s41392-023-01351-5.
[3] Sun, Hao, Zhang, Zhuo, Li, Tianda, Li, Ting, Chen, Weicai, Pan, Tianshi, Fang, Sen, Liu, Chao, Zhang, Ying, Wang, Leyun, Feng, Guihai, Li, Wei, Zhou, Qi, Zhao, Yuzheng. Live-cell imaging reveals redox metabolic reprogramming during zygotic genome activation. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2023, 238(9): 2039-2049, http://dx.doi.org/10.1002/jcp.31054.
[4] Wang, Xinge, Chen, Yangcan, Cheng, Xuejia, Wang, SiQi, Hu, Yanping, Feng, Yingmei, Jin, Ronghua, Zhou, Kangping, Liu, Ti, Wang, Jianxing, Pan, Kai, Liu, Bing, Xiang, Jie, Wang, Yanping, Zhou, Qi, Zhang, Ying, Pan, Weiye, Li, Wei. CDetection.v2: One-pot assay for the detection of SARS-CoV-2. FRONTIERS IN MICROBIOLOGY[J]. 2023, 14:1158163: http://dx.doi.org/10.3389/fmicb.2023.1158163.
[5] Wan, Haifeng, Fu, Rui, Tong, Man, Wang, Yukai, Wang, Libin, Wang, Siqi, Zhang, Ying, Li, Wei, Wang, XiuJie, Feng, Guihai. Influence of feeder cells on transcriptomic analysis of pluripotent stem cells. CELL PROLIFERATION[J]. 2022, 55(2): http://dx.doi.org/10.1111/cpr.13189.
[6] Ren, Jilong, Yu, Dawei, Wang, Jing, Xu, Kai, Xu, Yanan, Sun, Renren, An, Peipei, Li, Chongyang, Feng, Guihai, Zhang, Ying, Dai, Xiangpeng, Zhao, Hongye, Wang, Zhengzhu, Han, Zhiqiang, Zhu, Haibo, Ding, Yuchun, You, Xiaoyan, Liu, Xueqin, Wu, Meng, Luo, Lin, Li, Ziyi, Yang, YongGuang, Hu, Zheng, Wei, HongJiang, Ge, Liangpeng, Hai, Tang, Li, Wei. Generation of immunodeficient pig with hereditary tyrosinemia type 1 and their preliminary application for humanized liver. CELL AND BIOSCIENCE[J]. 2022, 12(1): http://dx.doi.org/10.1186/s13578-022-00760-3.
[7] Jiabao Han, Liyu Zhu, Jingwen Zhang, Lu Guo, Xuehan Sun, Cheng Huang, Kai Xu, Ying Zhang, Wei Li, Qi Zhou. Rational engineering of adeno-associated virus capsid enhances human hepatocyte tropism and reduces immunogenicity. Cell Proliferation[J]. 2022, 55(12): e13339-0, [8] ZhengQuan He, XueWei Yuan, ZongBao Lu, YuHuan Li, YuFei Li, Xin Liu, Liu Wang, Ying Zhang, Qi Zhou, Wei Li. Pharmacological regulation of tissue fibrosis by targeting the mechanical contraction of myofibroblasts. FUNDAMENTAL RESEARCH[J]. 2022, 2(1): 37-47, [9] He, ZhengQuan, Li, YuHuan, Feng, GuHai, Yuan, XueWei, Lu, ZongBao, Dai, Min, Hu, YanPing, Zhang, Ying, Zhou, Qi, Li, Wei. Pharmacological Perturbation of Mechanical Contractility Enables Robust Transdifferentiation of Human Fibroblasts into Neurons. ADVANCED SCIENCE[J]. 2022, 9(13): http://dx.doi.org/10.1002/advs.202104682.
[10] Zhu, Haibo, Sun, Hao, Yu, Dawei, Li, Tianda, Hai, Tang, Liu, Chao, Zhang, Ying, Chen, Yurong, Dai, Xiangpeng, Li, Ziyi, Li, Wei, Liu, Ruizhi, Feng, Guihai, Zhou, Qi. Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY[J]. 2021, 9: 0-0, [11] Mao, Yihuan, Wang, Libin, Zhong, Bei, Yang, Ning, Li, Zhikun, Cui, Tongtong, Feng, Guihai, Li, Wei, Zhang, Ying, Zhou, Qi. Continuous expression of reprogramming factors induces and maintains mouse pluripotency without specific growth factors and signaling inhibitors. CELL PROLIFERATION[J]. 2021, 54(8): http://dx.doi.org/10.1111/cpr.13090.
[12] Guanyi Jiao, Chenxin Wang, Yangcan Chen, Moyu Dai, Ying Zhang, Wei Li. Enhancing targeted transgene knock-in by donor recruitment. CELL PROLIFERATION[J]. 2021, 55(1): 0-0, [13] Fu, Rui, Yu, Dawei, Ren, Jilong, Li, Chongyang, Wang, Jing, Feng, Guihai, Wang, Xuepeng, Wan, Haifeng, Li, Tianda, Wang, Libin, Zhang, Ying, Hai, Tang, Li, Wei, Zhou, Qi. Domesticated cynomolgus monkey embryonic stem cells allow the generation of neonatal interspecies chimeric pigs. PROTEIN & CELL[J]. 2020, 11(2): 97-107, http://lib.cqvip.com/Qikan/Article/Detail?id=7101576097.
[14] Li, Yuhuan, Guo, Lu, Ying, Sunyang, Feng, GuiHai, Zhang, Ying. Transcriptional repression of p21 by EIF1AX promotes the proliferation of breast cancer cells. CELL PROLIFERATION[J]. 2020, 53(10): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7574879/.
[15] Ren, Jilong, Yu, Dawei, Fu, Rui, An, Peipei, Sun, Renren, Wang, Zhengzhu, Guo, Runfa, Li, Haoyun, Zhang, Ying, Li, Ziyi, Yang, YongGuang, Li, Wei, Hai, Tang, Hu, Zheng. IL2RG-deficient minipigs generated via CRISPR/Cas9 technology support the growth of human melanoma-derived tumours. CELL PROLIFERATION[J]. 2020, 53(10): http://dx.doi.org/10.1111/cpr.12863.
[16] Qu, Bin, Wu, Shijing, Jiao, Guanyi, Zou, Xuan, Li, Zhikun, Guo, Lu, Sun, Xuehan, Huang, Cheng, Sun, Zixi, Zhang, Ying, Li, Hui, Zhou, Qi, Sui, Ruifang, Li, Wei. Treating Bietti crystalline dystrophy in a high-fat diet-exacerbated murine model using gene therapy. GENE THERAPY[J]. 2020, 27(7-8): 370-382, http://dx.doi.org/10.1038/s41434-020-0159-3.
[17] Mao, Junjie, Xu, Kai, Han, Jiabao, Feng, Guihai, Zhang, Ying, Li, Wei. Rapid construction of a whole-genome mutant library by combining haploid stem cells and inducible self-inactivating PiggyBac transposon. PROTEIN & CELL[J]. 2020, 11(6): 452-457, http://lib.cqvip.com/Qikan/Article/Detail?id=7102355335.
[18] Li, Jing, Wang, Chenxin, Feng, Guihai, Zhang, Linlin, Chen, Guilai, Sun, Hao, Wang, Jiaqiang, Zhang, Ying, Zhou, Qi, Li, Wei. Rbm14 maintains the integrity of genomic DNA during early mouse embryogenesis via mediating alternative splicing. CELL PROLIFERATION[J]. 2020, 53(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000500078600001.
[19] Wang, Lei, Wu, Wei, Gu, Qi, Liu, Zengping, Li, Qiyou, Li, Zhongwen, Fang, Jinhui, Liu, Wenjing, Wu, Jun, Zhang, Ying, Wang, Liu, Xu, Haiwei, Li, Wei, Hu, Baoyang, Zhou, Qi, Yin, Zhengqin, Hao, Jie. The effect of clinical-grade retinal pigment epithelium derived from human embryonic stem cells using different transplantation strategies. PROTEIN & CELL[J]. 2019, 10(6): 455-460, http://lib.cqvip.com/Qikan/Article/Detail?id=7002265647.
[20] Malbec, Lionel, Zhang, Ting, Chen, YuSheng, Zhang, Ying, Sun, BaoFa, Shi, BoYang, Zhao, YongLiang, Yang, Ying, Yang, YunGui. Dynamic methylome of internal mRNA N-7-methylguanosine and its regulatory role in translation. CELL RESEARCH[J]. 2019, 29(11): 927-941, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889513/.
[21] Li, Zhongwen, Wu, Jun, Wang, Lei, Han, Weifang, Yu, Juan, Liu, Xin, Wang, Yukai, Zhang, Ying, Feng, Guihai, Li, Wei, Stacey, Glyn Niger, Gu, Qi, Hu, Baoyang, Wang, Liu, Zhou, Qi, Hao, Jie. Generation of qualified clinical-grade functional hepatocytes from human embryonic stem cells in chemically defined conditions. CELLDEATHDISEASE[J]. 2019, 10(10): http://dx.doi.org/10.1038/s41419-019-1967-5.
[22] Li, Yufei, Wang, Leyun, Zhang, Linlin, He, Zhengquan, Feng, Guihai, Sun, Hao, Wang, Jiaqiang, Li, Zhikun, Liu, Chao, Han, Jiabao, Mao, Junjie, Li, Pengcheng, Yuan, Xuewei, Jiang, Liyuan, Zhang, Ying, Zhou, Qi, Li, Wei. Cyclin B3 is required for metaphase to anaphase transition in oocyte meiosis I. JOURNAL OF CELL BIOLOGY[J]. 2019, 218(5): 1553-1563, https://www.webofscience.com/wos/woscc/full-record/WOS:000466980400014.
[23] Zhong, Xiuying, Cui, Peng, Cai, Yongping, Wang, Lihua, He, Xiaoping, Long, Peipei, Lu, Kangyang, Yan, Ronghui, Zhang, Ying, Pan, Xin, Zhao, Xiaoyang, Li, Wei, Zhang, Huafeng, Zhou, Qi, Gao, Ping. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. CELL METABOLISM[J]. 2019, 29(4): 979-+, http://dx.doi.org/10.1016/j.cmet.2018.11.007.
[24] Yuan, Xuewei, He, Zhengquan, Mao, Junjie, Hu, Yanping, Liu, Xin, Guo, Jia, Liu, Zhonghua, Zhang, Ying, Li, Wei, Zhou, Qi. Reprogramming of fibroblasts to uterine glandular epithelium by a chemical cocktail induction. CELL DISCOVERY[J]. 2019, 5(1): http://dx.doi.org/10.1038/s41421-019-0096-8.
[25] Zhang, Wei, Feng, Guihai, Wang, Libin, Teng, Fei, Wang, Liu, Li, Wei, Zhang, Ying, Zhou, Qi. MeCP2 deficiency promotes cell reprogramming by stimulating IGF1/AKT/mTOR signaling and activating ribosomal protein-mediated cell cycle gene translation. JOURNALOFMOLECULARCELLBIOLOGY[J]. 2018, 10(6): 515-526, https://www.webofscience.com/wos/woscc/full-record/WOS:000455316500004.
[26] Chen, Guilai, Zhang, Da, Zhang, Linlin, Feng, Guihai, Zhang, Boya, Wu, Yihui, Li, Wei, Zhang, Ying, Hu, Baoyang. RBM14 is indispensable for pluripotency maintenance and mesoderm development of mouse embryonic stem cells. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS[J]. 2018, 501(1): 259-265, http://dx.doi.org/10.1016/j.bbrc.2018.04.231.
[27] Zhang, Ying, Guo, Lu, Li, Yuhuan, Feng, GuiHai, Teng, Fei, Li, Wei, Zhou, Qi. MicroRNA-494 promotes cancer progression and targets adenomatous polyposis coli in colorectal cancer. MOLECULAR CANCER[J]. 2018, 17(1): https://doaj.org/article/f9ae56d34daf40d7918e42f9a6ba1416.
[28] Li, Xia, Ma, Ruoyu, Gu, Qi, Liang, Lingmin, Wang, Lei, Zhang, Ying, Wang, Xianning, Liu, Xin, Li, Zhongwen, Fang, Jinhui, Wu, Jun, Wang, Yukai, Li, Wei, Hu, Baoyang, Wang, Liu, Zhou, Qi, Hao, Jie. A fully defined static suspension culture system for large-scale human embryonic stem cell production. CELL DEATH & DISEASE[J]. 2018, 9: https://doaj.org/article/517fbb632f3142c385073e2f1824afd8.
[29] Li, ZhiKun, Wang, LeYun, Wang, LiBin, Feng, GuiHai, Yuan, XueWei, Liu, Chao, Xu, Kai, Li, YuHuan, Wan, HaiFeng, Zhang, Ying, Li, YuFei, Li, Xin, Li, Wei, Zhou, Qi, Hu, BaoYang. Generation of Bimaternal and Bipaternal Mice from Hypomethylated Haploid ESCs with Imprinting Region Deletions. CELL STEM CELL[J]. 2018, 23(5): 665-+, http://dx.doi.org/10.1016/j.stem.2018.09.004.
[30] Tan, Yuanqing, Han, Pengcheng, Gu, Qi, Chen, Gang, Wang, Lei, Ma, Ruoyu, Wu, Jun, Feng, Chunjing, Zhang, Ying, Wang, Liu, Hu, Baoyang, Li, Wei, Hao, Jie, Zhou, Qi. Generation of clinical-grade functional cardiomyocytes from human embryonic stem cells in chemically defined conditions. JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE[J]. 2018, 12(1): 153-163, https://www.webofscience.com/wos/woscc/full-record/WOS:000423431200070.
[31] Zhang Ying, Cui Peng, Li Yuhuan, Feng Guihai, Tong Man, Guo Lu, Li Tianda, Liu Lei, Li Wei, Zhou Qi. Mitochondrially produced ATP affects stem cell pluripotency via ActI6a-mediated histone acetylation. FASEB JOURNAL[J]. 2018, 32(4): 1891-1902, https://www.webofscience.com/wos/woscc/full-record/WOS:000429051400013.
[32] Zhang, Ying, Zhou, Qi. A single-cell snapshot of cell-fate decisions. JOURNAL OF BIOLOGICAL CHEMISTRY. 2017, 292(23): 9855-+, http://dx.doi.org/10.1074/jbc.H117.780585.
[33] He, ZhengQuan, Xia, BaoLong, Wang, YuKai, Li, Jing, Feng, GuiHai, Zhang, LinLin, Li, YuHuan, Wan, HaiFeng, Li, TianDa, Xu, Kai, Yuan, XueWei, Li, YuFei, Zhang, XinXin, Zhang, Ying, Wang, Liu, Li, Wei, Zhou, Qi. Generation of Mouse Haploid Somatic Cells by Small Molecules for Genome-wide Genetic Screening. CELL REPORTS[J]. 2017, 20(9): 2227-2237, http://dx.doi.org/10.1016/j.celrep.2017.07.081.
[34] 张映, 周琪. 单倍体胚胎干细胞的获得与应用前景. 生命科学[J]. 2017, 29(10): 977-982, http://lib.cqvip.com/Qikan/Article/Detail?id=674160594.
[35] Zhang, Ying, Wang, Shuling, Li, Lingsong. EF Hand Protein IBA2 Promotes Cell Proliferation in Breast Cancers via Transcriptional Control of Cyclin D1. CANCER RESEARCH[J]. 2016, 76(15): 4535-4545, [36] 曲彬, 张映, 周琪, 李伟. 人类胚胎基因编辑——科学与伦理. 科学与社会[J]. 2016, 6(3): 22-31, http://lib.cqvip.com/Qikan/Article/Detail?id=670264002.
[37] Feng, GuiHai, Tong, Man, Xia, BaoLong, Luo, GuanZheng, Wang, Meng, Xie, DongFang, Wan, HaiFeng, Zhang, Ying, Zhou, Qi, Wang, XiuJie. Ubiquitously expressed genes participate in cell-specific functions via alternative promoter usage. EMBO REPORTS[J]. 2016, 17(9): 1304-1313, https://www.webofscience.com/wos/woscc/full-record/WOS:000383630900013.
[38] Chen, Tong, Hao, YaJuan, Zhang, Ying, Li, MiaoMiao, Wang, Meng, Han, Weifang, Wu, Yongsheng, Lv, Ying, Hao, Jie, Wang, Libin, Li, Ang, Yang, Ying, Jin, KangXuan, Zhao, Xu, Li, Yuhuan, Ping, XiaoLi, Lai, WeiYi, Wu, LiGang, Jiang, Guibin, Wang, HaiLin, Sang, Lisi, Wang, XiuJie, Yang, YunGui, Zhou, Qi. m(6)A RNA methylation is regulated by microRNAs and promotes reprogramming to pluripotency. CELL STEM CELL[J]. 2015, 16(3): 289-301, https://www.webofscience.com/wos/woscc/full-record/WOS:000350747700015.
[39] Zhang, Ying, Teng, Fei, Luo, GuanZheng, Wang, Meng, Tong, Man, Zhao, XiaoYang, Wang, Liu, Wang, XiuJie, Zhou, Qi. MicroRNA-323-3p regulates the activity of polycomb repressive complex 2 (PRC2) via targeting the mRNA of embryonic ectoderm development (Eed) gene in mouse embryonic stem cells. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 288(33): 23659-23665, http://dx.doi.org/10.1074/jbc.M113.475608.
[40] Liu, Xin, Zhang, Ying, Tong, Man, Liu, XiuYing, Luo, GuanZheng, Xie, DongFang, Ren, ShaoFang, Bai, DongHui, Wang, Liu, Zhou, Qi, Wang, XiuJie. Identification of a small molecule 1,4-bis-4-(3-phenoxy-propoxy)-but-2-ynyl-piperazine as a novel inhibitor of the transcription factor p53. ACTA PHARMACOLOGICA SINICA[J]. 2013, 34(6): 805-810, https://www.webofscience.com/wos/woscc/full-record/WOS:000319915000012.
[41] Li, Wei, Zhao, Xiaoyang, Wan, Haifeng, Zhang, Ying, Liu, Lei, Lv, Zhuo, Wang, XiuJie, Wang, Liu, Zhou, Qi. iPS cells generated without c-Myc have active Dlk1-Dio3 region and are capable of producing full-term mice through tetraploid complementation. CELL RESEARCH. 2011, 21(3): 550-553, http://lib.cqvip.com/Qikan/Article/Detail?id=37538326.