基本信息

蔡潭溪 男 中国科学院生物物理研究所
电子邮件: txcai@moon.ibp.ac.cn
通信地址: 北京市朝阳区大屯路15号8115室
邮政编码: 100101
电子邮件: txcai@moon.ibp.ac.cn
通信地址: 北京市朝阳区大屯路15号8115室
邮政编码: 100101
招生信息
招生专业
071010-生物化学与分子生物学
招生方向
蛋白质组学、脂质组学
教育背景
2011-09--2015-01 中国科学院大学 博士学位1999-09--2006-06 南京农业大学 学士,硕士学位
工作经历
工作简历
2015-01~现在, 中国科学院生物物理研究所, 副研究员2011-09~2015-01,中国科学院大学, 博士学位2006-07~2014-12,中国科学生物物理研究所, 助理研究员1999-09~2006-06,南京农业大学, 学士,硕士学位
教授课程
分析生物化学及样品制备生物技术药物生命科学研究中的色谱、质谱和组学技术ABSP lab exercise生物样品分离与质谱鉴定技术
专利与奖励
奖励信息
(1) 中国科学院宝洁优秀研究生奖学金, 一等奖, 院级, 2015(2) 第12届全国脂质与脂蛋白学术会议“阳普”优秀论文奖, 二等奖, 专项, 2014(3) 生物物理研究所2014年度所长论文奖, 一等奖, 研究所(学校), 2014(4) 中国科学院三好学生, 一等奖, 院级, 2013(5) 中国分析测试协会科学技术奖, 一等奖, 专项, 2011
专利成果
( 1 ) 一种用于富集内源性低分子量蛋白和多肽的试剂盒及方法, 2020, 第 3 作者, 专利号: 202010519120.8( 2 ) 一种基于稳定同位素标记的磷脂分类检测和定量方法, 2019, 第 1 作者, 专利号: 201510446558.7( 3 ) 一种基于化学衍生的磷脂分类检测和定量方法, 2017, 第 1 作者, 专利号: 201510446589.2( 4 ) 一种逆流色谱仪及其专用逆流色谱柱, 2012, 第 2 作者, 专利号: 201120031345.5
出版信息
发表论文
(1) Deeply Mining a Universe of Peptides Encoded by Long Noncoding RNAs., Mol Cell Proteomics ., 2021, 第 1 作者(2) LncRNA-encoded microproteins: A new form of cargo in cell culture-derived and circulating extracellular vesicles, Journal of Extracellular Vecicles, 2021, 第 1 作者(3) Proteomics reveals the function reverse of MPSSS‐treated prostate cancer‐associated fibroblasts to suppress PC‐3 cell viability via the FoxO pathway, Cancer medicine, 2021, 第 5 作者(4) Sequential Precipitation and Delipidation Enables Efficient Enrichment of Low-Molecular Weight Proteins and Peptides from Human Plasma, J. Proteome Res., 2020, 通讯作者(5) Separation and characterization of extracellular vesicles from human plasma by asymmetrical flow field-flow fractionation, Anal Chim Acta ., 2020, 第 8 作者(6) Phospholipid and Phospholipidomics in Health and Diseases, Phospholipid and Phospholipidomics in Health and Diseases, 2018, 第 1 作者(7) MicroRNA-202 maintains spermatogonial stem cells by inhibiting cell cycle regulators and RNA binding proteins., Nucleic Acids Res., 2017, 第 1 作者(8) Strategies for Characterization of Low-Abundant Intact or Truncated Low-Molecular-Weight Proteins From Human Plasma., Enzymes, 2017, 第 1 作者(9) CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development., Proc Natl Acad Sci U S A, 2017, 第 4 作者(10) SmProt: a database of small proteins encoded by annotated coding and non-coding RNA loci., Brief Bioinform., 2017, 第 4 作者(11) Pore architecture of TRIC channels and insights into their gating mechanism., Nature, 2016, 第 5 作者(12) Characterization and relative quantification of phospholipids based on methylation and stable isotopic labeling, Journal of Lipid Research, 2016, 第 1 作者(13) Profiling and relative quantitation of phosphoinositides by multiple precursor ion scanning based on phosphate methylation and isotopic labeling., Analytical Chemistry, 2015, 第 1 作者(14) Proteomic Comparison and MRM-Based Comparative Analysis of Metabolites Reveal Metabolic Shift in Human Prostate Cancer Cell Lines, Jouranl of Proteome Research, 2015, 第 1 作者(15) Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins, Mol Cell Proteomics, 2015, 第 1 作者(16) Integrative proteomic and transcriptomic analyses reveal multiple post-transcriptional regulatory mechanisms of mouse spermatogenesis, Mol Cell Proteomics, 2013, 第 1 作者(17)
科研活动
科研项目
( 1 ) 高密度脂蛋白主要组成成分及其修饰的动态变化与糖尿病和冠心病之间的关联性研究, 负责人, 国家任务, 2017-01--2020-12( 2 ) 基于中药复方抗糖尿病新靶标的发现, 参与, 中国科学院计划, 2016-01--2018-12( 3 ) Study on the pathogenesis of obesity and type 2 diabetes mellitus (T2DM) using comparative lipoproteomics approach, 参与, 中国科学院计划, 2016-01--2016-12
参与会议
(1)Characterization and relative quantification of phospholipids based on methylation and stable isotopic labeling 2016-06-05(2)Lysine malonylation is elevated in type 2 diabetic mouse models and enriched in metabolic associated proteins. 2015-07-06(3)Comparative proteomics-based in silico analyzes further our understanding of mouse spermatogenesis and fertility 2014-06-04