Swine amino acid nutrition, development and regulation of conceptus in Chinese local pig breeds, development and regulation of gut microorganism in pig, development of Chinese herbal feed additives.

        B.A.    1996.9-2000.7    Henan Agricultural University (Veterinary Medicine)
        M.S.    2000.9-2003.7    Nanjing Agricultural University (Clinical Veterinary Medicine)
        Ph.D.    2003.9-2006.7    Nanjing Agricultural University (Clinical Veterinary Medicine)

   

       7/2006-10/2007    Assistant Professor    Institute of Subtropical Agriculture, Chinese Academy of Sciences 
       9/2007-12/2009    Post doctor    Nanchang University (Swine nutrition and dietary additive) 
      10/2007-8/2012    Associate Professor    Institute of Subtropical Agriculture, Chinese Academy of Sciences 
      2/2008-2/2009    Visiting scholar    Department of Animal Science, Texas A&M University (Nutritional biochemistry of amino acids) 
      2012.8-2013.2    Visiting scholar    UMR914 National Institute for Agronomic Research (INRA)-AgroParisTech, France (Colon microorganism metabolism and gut health) 
     8/2012- present    Professor    Institute of Subtropical Agriculture, Chinese Academy of Sciences 

   

[1]  XF Kong, YL Hu, R Rui, et al. Effects of Chinese herbal medicinal ingredients on peripheral lymphocyte proliferation and serum antibody titer after vaccination in Chicken. Int Immunopharmacol, 2004, (4): 975-982.
[2]  XF Kong, YL Hu, YL Yin, et al. Chinese herbal ingredients are effective immune stimulators for Chickens infected with the Newcastle disease virus. Poult Sci, 2006, 85(12): 2169- 2175.
[3]  XF Kong, GY Wu, YP Liao, et al. Effects of Chinese herbal ultra-fine powder as a dietary additive on growth performance, serum metabolites and intestinal health in early-weaned piglets. Livest Sci, 2007, 108: 272-275.
[4]  XF Kong, GY Wu, YP Liao, et al. Dietary supplementation with Chinese herbal ultra-fine powder enhances cellular and humoral immunity in early-weaned piglets. Livest Sci, 2007, 108: 94-98.
[5]  XF Kong, YL Yin, GY Wu, et al. Dietary supplementation with Acantho- panax senticosus extract modulates cellular and humoral immunities in weaned piglets. Asian-Aust J Anim Sci, 2007, 20(9): 1453-1461.
[6]  XF Kong, YL Yin, QH He, et al. Dietary supplementation with Chinese herbal powder enhances ileal digestibilities and serum concentrations of amino acids in young pigs. Amino Acids, 2009, 37: 573-582.
[7]  XF Kong, FG Yin, QH He, et al. Acanthopanax senticosus extracts as a dietary additive enhances the apparent ileal digestibility of amino acids in weaned piglets. Livest Sci, 2009, 123(2-3):261-267.
[8]  XF Kong, YZ Zhang, YL Yin, et al. Chinese Yam polysaccharide enhances growth performance and cellular immune response in weanling rats. J Sci Food & Agric, 2009, 89: 2039-2044.
[9]  XF Kong, YZ Zhang, X Wu, et al. Fermentation characterization of the Chinese Yam polysaccharide and its effects on the gut microbiota of rats. Int J Microb, 2009, doi:10.1155/ 2009/598152.
[10]  XF Kong, GY Wu, YL Yin. Roles of phytochemicals in amino acid nutrition. Front Biosci, 2011, S3: 372-384.
[11]  XF Kong, BE Tan, YL Yin, et al. Arginine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. J Nutr Biochem, 2012, 23: 1178-1183.
[12]  ZM Feng, JP Guo, XF Kong*, et al. Molecular cloning and expression profiling of G protein coupled receptor 120 in Landrace pig and different Chinese indigenous pig breeds. J Food Agric & Environ, 2012, 10: 809-814.
[13]  ZM Feng, JP Guo, XF Kong*, et al. Which housekeeping gene can be well used in gene expression analysis in Chinese local pig breeds. J Food Agric & Environ, 2012, 10: 825-833.
[14]  HS Yang, DZ Fu, H Shao, XF Kong*, et al. Impacts of birth weight on plasma, liver and skeletal muscle neutral amino acid profiles and intestinal amino acid transporters in suckling Huanjiang mini- piglets. Plos ONE, 2012, 7(12): e50921.
[15]  ZM Feng, XL Zhou, H Shao, XF Kong*, et al. Genotyping of five Chinese local pig breeds focused on meat quality by using PCR-RFLP based on halothane and Mx1. J Food Agric & Environ, 2012, 10: 840-845.
[16]  DZ Fu, HS Yang, XF Kong*, et al. Molecular cloning and expression profiling of excitatory amino acid carrier 1 in Huanjiang mini-piglets with different body weight. Mol Biol Rep, 2013, 40(4): 3341-3350.
[17]  WC Wang, F Blachier, DZ Fu, J Pan, HS Yang, JP Guo, WY Chu, XF Kong*, et al. Ontogenic expression of the amino acid transporter b0,+ AT in suckling Huanjiang mini-piglets with different body weight. Br J Nutr, 2013, 110: 823-830.
[18]  Kong XF, XQ Wang, YL Yin, et al. Putrescine stimulates the mTOR signaling pathway and protein synthesis in porcine trophectoderm cells. Biol Reprod, 2014, 91(5): 106, 1-10.
[19]  XF Kong, XL Zhou, GQ Lian, et al. Dietary supplementation with chitooligosaccharides alters gut microbiota and modifies intestinal luminal metabolites in weaned Huanjiang mini-piglets. Livest Sci, 2014, 160: 97-101.
[20]  XL Zhou, XF Kong*, GQ Lian, et al. Dietary supplementation with soybean oligosaccharides increases short-chain fatty acids but decreases protein-derived catabolites in the intestinal luminal content of weaned Huanjiang mini-piglets. Nutr Res, 2014, 34: 780-788.
[21]  XF Kong*, XL Zhou, ZM Feng, et al. Dietary supplementation with monosodium L-glutamate modifies lipid composition and gene expression related to lipid metabolism in growing pigs fed a normal- or high-fat diet. Livest Sci, 2015, http://dx.doi.org/10.1016/j.livsci.2015.06.023.
[22]  YY Liu, FN Li, LY He, BE Tan, JP Deng, XF Kong*, et al. Dietary protein intake affects expression of genes for lipid metabolism in porcine skeletal muscle in a genotype-dependent manner. Brit J Nutr, 2015, 113: 1069-1077.
[23]  YY Liu, XF Kong (Co-first author), GL Jiang, et al. Effects of dietary protein to energy ratios on growth performance, carcass characteristics, meat quality, and plasma biochemical parameters in growing-finishing pigs with different genotypes. J Anim Sci & Biotechnol, 2015, DOI: 10.1186/s40104-015-0036-x
[24]  YY Liu, XF Kong (Co-first author), FN Li, et al. Co-dependence of the genotype and the dietary protein intake on the gene expression of amino acid/peptide transporters in porcine skeletal muscle. Amino Acids, 2015, DOI 10.1007/s00726-015-2066-2. 
[25]  DY Wang, YL Hu, JL Sun, XF Kong, et al. Comparative study on adjuvanticity of compound Chinese herbal medicinal ingredients. Vaccine, 2005, 23: 3704-3708.
[26]  Y Qiu, YL Hu, BA Cui, HY Zhang, XF Kong, et al. Immunopotentiating effects of four Chinese herbal polysaccharides administered at vaccination in chickens. Poult Sci, 2007, 86(12): 2530-2535.
[27]  FG Yin, YL Yin, XF Kong, et al. Dietary supplementation with Acanthopanax senticosus extract modulates gut microflora in weaned piglets. Asian-Aust J Anim Sci, 2008, 21(9): 1330-1338.
[28]  YL Yin, TJ Li, RL Huang, ZQ Liu, XF Kong, et al. Evaluating standardized ileal digestibility of amino acids in growing pigs. Anim Feed Sci & Tech, 2008, 140: 385-401.
[29]  Y Lu, YL Hu, XF Kong, et al. Selection of component drug in activating blood flow and removing blood stasis of Chinese herbal medicinal formula for dairy cow mastitis by hemorheological method. J Ethnopharmac, 2008, 116: 313-317.
[30]  J Fang, FY Yan, XF Kong, et al. Dietary supplementation of Acanthopanax senticosus extract enhances gut health in weanling piglets. Livest Sci, 2009, 123(2-3): 268-275.
[31]  QH He, XF Kong, GY Wu, et al. Metabolomic analysis of the response of growing pigs to dietary L-arginine supplementation. Amino Acids, 2009, 37: 199-208.
[32]  BE Tan, XG Li, XF Kong, et al. Dietary L-arginine supplementation enhances the immune status of early-weaned piglets. Amino Acids, 2009, 37(2): 323-331.
[33]  W Du, YJ Li, GY Zhao, YL Yin, XF Kong. Effect of dietary energy level on nutrient utilization, insulin-like growth factor-I and insulin-like growth factor binding protein-3 in plasma, liver and longissimus dorsi muscle in growing- finishing pigs using soybean oil as an energy source. Asian-Aust I Anim Sci, 2009, 22(8): 1180-1185.
[34]  BE Tan, YL Yin, XF Kong, et al. L-Arginine stimulates proliferation and prevents endotoxin-induced death of intestinal cells. Amino Acids, 2010, 38: 1227-1235.
[35]  JY Yang, YF Zhang, AM Liang, XF Kong, et al. Toxic effects of T-2 toxin on reproductive system in male mice. Toxicol & Indust Health, 2010, 26(1): 25-31.
[36]  MM Geng, TJ Li, XF Kong, et al. Reduced expression of intestinal N-acetylglutamate synthase in suckling piglets: a novel molecular mechanism for arginine as a nutritionally essential amino acid for neonates. Amino Acids, 2011, 40: 1513-1522.
[37]  QH He, PP Ren, XF Kong, et al. Intrauterine growth restriction alters the metabonome of the serum and jejunum in piglets. Mol BioSys, 2011, 7: 2147-2155.
[38]  QH He, HR Tang, PP Ren, XF Kong, et al. Dietary supplementation with L-arginine partially counteracts serum metabonome induced by weaning stress in piglets. J Proteome Res, 2011, (10): 5214-5221.
[39]  QH He, YL Yin, F Zhao, XF Kong, et al. Metabonomics and its role in amino acid nutrition research. Front Biosci, 2011, 16: 2451-2460.
[40]  FN Li, YL Yin, BE Tan, XF Kong, et al. Leucine nutrition in animals and humans: mTOR signaling and beyond. Amino Acids, 2011, 41(5): 1185-1193.
[41]  BE Tan, YL Yin, ZQ Liu, WJ Tang, HJ Xu, XF Kong, et al. Dietary L-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle. J Nutr Biochem, 2011, 22: 441-445.
[42]  XL Zhou, XF Kong, XJ Yang, et al. Soybean oligosaccharides alter short-chain fatty acid production and microbial population of colon in vitro. Journal of Animal Science, 2012, 90: 37-39.
[43]  QH He, PP Ren, XF Kong, et al. Comparison of serum metabolite compositions between obese and lean growing pigs using an NMR-based metabonomic approach. J Nutr Biochem, 2012, 23: 133-139.
[44]  HS Yang, FN Li, XF Kong, et al. Molecular cloning, tissue distribution and ontogenetic expression of Xiang pig Chemerin and its involvement in regulating energy metabolism through Akt and ERK1/2 signaling pathways. Mol Biol Rep, 2012, 39: 1887-1894.
[45]  HS Yang, FN Li, XF Kong, et al. Chemerin regulates proliferation and differentiation of myoblast cells via ERK1/2 and mTOR signaling pathways. Cytokine, 2012, 60(3): 646-652.
[46]  BE Tan, XG Li, GY Wu, XF Kong, et al. Dynamic changes in blood flow and oxygen consumption in the portal-drained viscera of growing pigs receiving acute administration of L-arginine. Amino Acids, 2012, 43: 2481-2489.
[47]  XS Tang, H Shao, TJ Li, ZR Tang, RL Huang, SP Wang, XF Kong, et al. Dietary supplementation with bovine Lactoferrampin-lactoferricin produced by Pichia pastoris fed-batch fermentation affects intestinal microflora in weaned piglets. Applied Biochem & Biotech, 2012, 168: 887-898.
[48]  HS Yang, DZ Fu, XF Kong, et al. Dietary supplementation with N-carbamyglutamate increases the expression of intestinal amino acid transporters in weaned Huanjiang mini-piglets. J Anim Sci, 2013, 91(6): 2740-2748.
[49]  HS Yang, FN Li, X Xiong, XF Kong, et al. Soy isoflavones modulate adipokines and myokines to regulate lipid metabolism in adipose tissue, skeletal muscle and liver of male Huanjiang mini-pigs. Mol Cell Endocrinol, 2013, 365(1): 44-51.
[50]  YH Li, FN Li, BB Lin, XF Kong, et al. Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes. Mol Biol Rep, 2014, 41:7543-7553.
[51]  ZM Feng, XL Zhou, F Wu, K Yao, XF Kong, et al. Both dietary supplementation with monosodium L-glutamate and fat modify circulating and tissue amino acid pools in growing pigs, but with little interactive effect. PLoS One, 2014; 9(1): e84533.
[52]  FN Li, YH Li, YL Tang, BB Lin, XF Kong, et al. Protective effect of myokine IL-15 against H2O2-mediated oxidative stress in skeletal muscle cells. Mol Biol Rep, 2014, 41: 7715-7722.
[53]  YL Tang, FN Li, BE Tan, G Liu, XF Kong, et al. Enterotoxigenic Escherichia coli infection induces intestinal epithelial cell autophagy. Vet Microbiol, 2014, 171(1-2): 160-164.
[54]  WK Ren, G Liu, J Yin, S Chen, TJ Li, XF Kong, et al. Draft genome sequence of enterotoxigenic Escherichia coli strain W25K. Genome Announc, 2014, 2(3): e00593-14.
[55]  A Lan, F Blachier, R Benamouzig, M Beaumont, C Barrat, D Coelho, A Lancha Jr, XF Kong, et al. Mucosal healing in inflammatory bowel diseases: is there a place for nutritional supplementation? Inflamm Bowel Dis, 2015, 21(1):198-207.
[56]  YL Tang, BE Tan, X Xiong, FN Li, WK Ren, XF Kong, et al. Methionine deficiency reduces autophagy and accelerates death in intestinal epithelial cells infected with enterotoxigenic Escherichia coli. Amino Acids, 2015, DOI 10.1007/s00726-014-1781-4.
[57]  YH Duan, FN Li, KR Tan, HN Liu, YH Li, YY Liu, XF Kong, et al. Key mediators of intracellular amino acids signaling to mTORC1 activation. Amino Acids, 2015, 47:857-867.
[58]  M Andriamihaja, A Lan, M Beaumont, M Audebert, X Wong, K Yamada, YL Yin, D Tomé, C Carrasco-Pozo, M Gotteland, XF Kong, et al. The deleterious metabolic and genotoxic effects of the bacterial metabolite p-cresol on colonic epithelial cells. Free Rad Biol Med, 2015, 85: 219-227.

已指导学生

祝倩  硕士研究生  090502-动物营养与饲料科学  

张旺宏  硕士研究生  090502-动物营养与饲料科学  

马翠  硕士研究生  090502-动物营养与饲料科学  

唐武  硕士研究生  090502-动物营养与饲料科学  

刘雅婷  硕士研究生  090502-动物营养与饲料科学  

祝倩  博士研究生  071300-生态学  

现指导学生

程雅婷  硕士研究生  090500-畜牧学  

李锐煊  硕士研究生  085700-资源与环境