071010-生物化学与分子生物学
0710Z2-计算生物学

精神神经疾病的发生发展规律
神经精神疾病生物标志物的鉴定

2004-09--2009-06   北京大学   博士
1999-09--2004-06   山西医科大学   学士

   

2016-03~现在, 中国科学院心理研究所, 副研究员
2009-07~2016-02,中国科学院心理研究所, 助理研究员
2004-09~2009-06,北京大学, 博士
1999-09~2004-06,山西医科大学, 学士

   

（ 1 ） 自身免疫类神经疾病的诊断, 2021, 第 2 作者, 专利号: CN112285363A

（ 2 ） 一种人类大脑基因时空表达模式在线分析系统及其方法, 2019, 第 2 作者, 专利号: CN110428867A

（ 3 ） 一种人类大脑基因表达时空常模的建立方法, 2019, 第 2 作者, 专利号: CN110349625A

   

（1） Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia, Frontiers in Immunology, 2024, 第 1 作者
（2） 采用脑脊液宏基因组二代测序联合拷贝数变异分析技术辅助诊断脑膜癌病, Detection of meningeal carcinomatosis by metagenomic next-generation sequencing and copy number variation analysis of cerebrospinal fluid, 中华神经科杂志, 2023, 第 5 作者
（3） Preservation Analysis on Spatiotemporal Specific Co-expression Networks Suggests the Immunopathogenesis of Alzheimer's Disease, FRONTIERS IN AGING NEUROSCIENCE, 2021, 第 1 作者  通讯作者
（4） Prevalence and Correlates of Anxiety and Depressive Symptoms in Patients With and Without Multi-Drug Resistant Pulmonary Tuberculosis in China, FRONTIERS IN PSYCHIATRY, 2021, 第 5 作者  通讯作者
（5） Autoantibody against the Rab6A/Rab6B in primary autoimmune cerebellar ataxia associated with Sjogren's syndrome: A case report, JOURNAL OF NEUROIMMUNOLOGY, 2021, 第 1 作者
（6） A Systematic Analysis Revealed the Potential Gene Regulatory Processes of ATRA-Triggered Neuroblastoma Differentiation and Identified a Novel RA Response Sequence in the NTRK2 Gene, BIOMED RESEARCH INTERNATIONAL, 2020, 第 1 作者
（7） Identification of a missense ARSA mutation in metachromatic leukodystrophy and its potential pathogenic mechanism, MOLECULAR GENETICS & GENOMIC MEDICINE, 2020, 第 1 作者
（8） Identification of key genes and pathways for Alzheimer's disease via combined analysis of genome-wide expression profiling in the hippocampus, Biophysics Reports, 2019, 第 5 作者
（9） BEST: a web server for brain expression Spatio-temporal pattern analysis, BMC BIOINFORMATICS, 2019, 第 1 作者
（10） Identification of key genes and pathways for Alzheimer's disease via combined analysis of genome-wide expression profiling in the hippocampus, Identification of key genes and pathways for Alzheimer���s disease via combined analysis of genome-wide expression profiling in the hippocampus, 生物物理学报:英文版, 2019, 第 5 作者
（11） RSNPBase 3.0: an updated database of SNP-related regulatory elements, element-gene pairs and SNP-based gene regulatory networks, NUCLEIC ACIDS RESEARCH, 2018, 第 1 作者
（12） Common variants near IKZF1 are associated with primary Sjogren's syndrome in Han Chinese, PLOS ONE, 2017, 第 4 作者
（13） A combined analysis of genome-wide expression profiling of bipolar disorder in human prefrontal cortex, JOURNAL OF PSYCHIATRIC RESEARCH, 2016, 第 4 作者
（14） rVarBase: an updated database for regulatory features of human variants, NUCLEIC ACIDS RESEARCH, 2016, 第 1 作者
（15） I-GSEA4GWAS v2: a web server for functional analysis of SNPs in trait-associated pathways identified from genome-wide association study, PROTEIN & CELL, 2015, 第 3 作者
（16） Network analysis reveals a stress-affected common gene module among seven stress-related diseases/systems which provides potential targets for mechanism research, SCIENTIFIC REPORTS, 2015, 第 1 作者
（17） Applying Differentially Expressed Genes From Rodent Models of Chronic Stress to Research of Stress-Related Disease: An Online Database, PSYCHOSOMATIC MEDICINE, 2014, 第 1 作者
（18） Applying differentially expressed genes from rodent models of chronic stress to researches of stress-related disease: an online database, Psychosomatic Medicine., 2014, 第 1 作者
（19） rSNPBase: a database for curated regulatory SNPs, NUCLEIC ACIDS RESEARCH, 2014, 第 1 作者
（20） The neural correlates of reward-related processing in major depressive disorder: A meta-analysis of functional magnetic resonance imaging studies, JOURNAL OF AFFECTIVE DISORDERS, 2013, 第 3 作者
（21） MK4MDD: A Multi-Level Knowledge Base and Analysis Platform for Major Depressive Disorder, PLOS ONE, 2012, 第 1 作者
（22） ICSNPathway: identify candidate causal SNPs and pathways from genome-wide association study by one analytical framework, NUCLEIC ACIDS RESEARCH, 2011, 第 4 作者
（23） Mechanisms involved in phosphatidylinositol 3-kinase pathway mediated up-regulation of the mu opioid receptor in lymphocytes, BIOCHEMICAL PHARMACOLOGY, 2010, 第 3 作者
（24） The mechanism involved in the repression of the mu opioid receptor gene expression in CEM x 174 cells infected by simian immunodeficiency virus, JOURNAL OF LEUKOCYTE BIOLOGY, 2009, 第 3 作者
（25） Involvement of STAT5a signaling in morphine-induced up-regulation of the cyclin D1, BIOCHEMICAL PHARMACOLOGY, 2009, 第 1 作者

   

（ 1 ） 人脑视知觉认知数据计算与组织, 参与, 国家任务, 2015-01--2019-08
（ 2 ） 慢性温和应激环境下BALB/c小鼠全脑基因表达调控网络构建与分析, 负责人, 国家任务, 2013-01--2015-12