基本信息
高福平  女  硕导  中国科学院高能物理研究所
电子邮件: gaofp@ihep.ac.cn
通信地址: 石景山区玉泉路19号乙
邮政编码: 100049

招生信息

   
招生专业
0703Z2-生物无机化学
招生方向
纳米生物医学

教育背景

2005-09--2008-07   北京协和医学院清华大学医学部   获得博士研究生学位

工作经历

   
工作简历
2013-06~2014-06,中国科学院高能物理研究所, 助理研究员/副研究员
2010-08~2012-08,中国科学院理化技术研究所, 助理研究员
2008-07~2010-07,清华大学, 博士后
2005-09~2008-07,北京协和医学院清华大学医学部, 获得博士研究生学位

出版信息

   
发表论文
(1) The therapeutic effect of gold clusters in an EAE model of multiple sclerosis by regulating T cell differentiation, NANO TODAY, 2024, 第 11 作者  通讯作者
(2) Application of nanomaterials in the treatment of rheumatoid arthritis, RSC ADVANCES, 2021, 第 10 作者  通讯作者
(3) Peptide and protein modified metal clusters for cancer diagnostics, CHEMICAL SCIENCE, 2020, 第 3 作者
(4) Iodine-124 Labeled Gold Nanoclusters for Positron Emission Tomography Imaging in Lung Cancer Model, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2020, 第 3 作者
(5) Is GSH Chelated Pt Molecule Inactive in Anti-Cancer Treatment? A Case Study of Pt(6)GS(4), SMALL, 2020, 第 10 作者
(6) Inherently PET/CT Dual Modality Imaging Lipid Nanocapsules for Early Detection of Orthotopic Lung Tumors, ACS APPLIED BIO MATERIALS, 2020, 第 12 作者  通讯作者
(7) An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging, SCIENCE ADVANCES, 2020, 第 6 作者
(8) A chlorin-lipid nanovesicle nucleus drug for amplified therapeutic effects of lung cancer by internal radiotherapy combined with the Cerenkov radiation-induced photodynamic therapy, BIOMATERIALS SCIENCE, 2020, 第 9 作者  通讯作者
(9) Comparative study of core- and surface-radiolabeling strategies for the assembly of iron oxide nanoparticle-based theranostic nanocomposites, NANOSCALE, 2019, 第 8 作者
(10) Glutathione-Coated Au-29(SG)(27): Structural Determination Based on Different Combination Styles Confirmed by Experiments, JOURNAL OF PHYSICAL CHEMISTRY C, 2019, 第 3 作者
(11) Comparison of the Therapeutic Effects of Gold Nanoclusters and Gold Nanoparticles on Rheumatoid Arthritis, JOURNAL OF BIOMEDICAL NANOTECHNOLOGY, 2019, 第 8 作者  通讯作者
(12) Gold Clusters Prevent Inflammation-Induced Bone Erosion through Inhibiting the Activation of NF-kappa B Pathway, THERANOSTICS, 2019, 第 2 作者
(13) Dose-Dependent Efficacy of Gold Clusters on RheumatoidArthritis Therapy, ACS OMEGA, 2019, 第 5 作者  通讯作者
(14) Au clusters treat rheumatoid arthritis with uniquely reversing cartilage/bone destruction, ADVANCED SCIENCE, 2019, 第 1 作者
(15) Assembled Vitamin B2 Nanocrystals with Optical Waveguiding and Photosensitizing Properties for Potential Biomedical Application, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 3 作者
(16) Surface-Functionalized Modified Copper Sulfide Nanoparticles Enhance Checkpoint Blockade Tumor Immunotherapy by Photothermal Therapy and Antigen Capturing, ACS APPLIED MATERIALS & INTERFACES, 2019, 第 9 作者  通讯作者
(17) Exposure to Alumina Nanoparticles in Female Mice During Pregnancy Induces Neurodevelopmental Toxicity in the Offspring, FRONTIERS IN PHARMACOLOGY, 2018, 第 5 作者
(18) The Precise Diagnosis of Cancer Invasion/Metastasis via 2D Laser Ablation Mass Mapping of Metalloproteinase in Primary Cancer Tissue, ACS NANO, 2018, 第 4 作者
(19) Turning On/Off the Anti-Tumor Effect of the Au Cluster via Atomically Controlling Its Molecular Size, ACS NANO, 2018, 第 5 作者
(20) Au nanoclusters suppress chronic lymphocytic leukaemia cells by inhibiting thioredoxin reductase 1 to induce intracellular oxidative stress and apoptosis, SCIENCE BULLETIN, 2017, 第 11 作者
(21) Biomimetic construction of protein-conjugated gold clusters for detecting Hg2+, COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2017, 第 3 作者
(22) Ultrasmall superparamagnetic iron oxide nanoparticle for t-2-weighted magnetic resonance imaging, ACS APPLIED MATERIALS & INTERFACES, 2017, 
(23) Au Nanoclusters and Photosensitizer Dual Loaded Spatiotemporal Controllable Liposomal Nanocomposites Enhance Tumor Photodynamic Therapy Effect by Inhibiting Thioredoxin Reductase, ADVANCED HEALTHCARE MATERIALS, 2017, 第 1 作者  通讯作者
(24) Peptide-Au Cluster Probe: Precisely Detecting Epidermal Growth Factor Receptor of Three Tumor Cell Lines at a Single-Cell Level, ACS OMEGA, 2017, 第 4 作者
(25) Peptide protected gold clusters: chemical synthesis and biomedical applications, NANOSCALE, 2016, 第 5 作者
(26) Folic acid-conjugated superparamagnetic iron oxide nanoparticles for tumor-targeting MR imaging, DRUG DELIVERY, 2016, 第 8 作者  通讯作者
(27) One-pot synthesis of PEGylated plasmonic MoO3-x hollow nanospheres for photoacoustic imaging guided chemo-photothermal combinational therapy of cancer, BIOMATERIALS, 2016, 第 8 作者
(28) Folate-Conjugated Magnetic Nanoparticles for Tumor Hyperthermia Therapy: In Vitro and In Vivo Studies, JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 2016, 第 3 作者  通讯作者
(29) Peptide-Conjugated Gold Nanoprobe: Intrinsic Nanozyme-Linked Immunosorbent Assay of Integrin Expression Level on Cell Membrane., ACS NANO, 2015, 第 7 作者
(30) Ultrasmall [64Cu]Cu Nanoclusters for Targeting Orthotopic Lung Tumors Using Accurate Positron Emission Tomography Imaging, ACS Nano, 2015, 
(31) Ultrasmall Cu-64 Cu Nanoclusters for Targeting Orthotopic Lung Tumors Using Accurate Positron Emission Tomography Imaging, ACSNANO, 2015, 第 1 作者
(32) Peptide-conjugated gold nanoprobe: intrinsic nanozyme-linked immunsorbant assay of integrin expression level on cell membrane, ACS NANO, 2015, 第 7 作者
(33) Bio-inspired peptide-Au cluster applied for mercury (II) ions detection, SCIENCE CHINA-CHEMISTRY, 2015, 第 4 作者
(34) Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles, BIOMATERIALS, 2014, 第 1 作者
(35) In vivo tomographic imaging of lung colonization of tumour in mouse with simultaneous fluorescence and X-ray CT, JOURNAL OF BIOPHOTONICS, 2014, 第 2 作者
(36) Plasmon-Mediated Generation of Reactive Oxygen Species from Near-Infrared Light Excited Gold Nanocages for Photodynamic Therapy in Vitro, ACS NANO, 2014, 第 3 作者
(37) Detection of pH Change in Cytoplasm of Live Myocardial Ischemia Cells via the ssDNA-SWCNTs Nanoprobes, ANALYTICAL CHEMISTRY, 2014, 第 6 作者
(38) Supramolecular adducts of squaraine and protein for noninvasive tumor imaging and photothermal therapy invivo, BIOMATERIALS, 2014, 第 1 作者
(39) LHRH-PE40 Fusion Protein Tethered Silica Nanorattles for Imaging-Guided Tumor-Specifi c Drug Delivery and Bimodal Therapy, Advanced materials, 2013, 第 1 作者
(40) 纳米氧化铝致ICR小鼠脑氧化应激水平的改变, 中华劳动卫生职业病, 2011, 第 4 作者
(41) 纳米氧化铝致ICR小鼠脑氧化应激水平的改变, Changes of brain oxidative stress induced by nano-alumina in ICR mice, 中华劳动卫生职业病杂志, 2011, 第 3 作者
发表著作
( 1 ) 肿瘤热疗生物学, Tumor Hyperthermia Biology, 人民卫生出版社, 2010-06, 第 2 作者
( 2 ) 临床肿瘤学概论, Introduction to clinical oncology, 清华大学出版社, 2011-04, 第 5 作者
( 3 ) 磁性医药材料, Magnetic Medical Materials, 清华大学出版社出版, 2012-10, 第 4 作者

科研活动

   
科研项目
( 1 ) 金纳米团簇和光敏剂双负载的时空可控型脂质纳米复合体增强肿瘤光动力学治疗效应和机制研究, 负责人, 国家任务, 2017-01--2020-12
( 2 ) LHRH-PE40融合蛋白锚定的纳米复合体用于成像引导的肿瘤综合治疗研究, 负责人, 国家任务, 2015-01--2018-12
( 3 ) 多效一体的纳米“鸡尾酒”用于可视化肺癌靶向双模式治疗研究, 负责人, 地方任务, 2015-01--2017-12
( 4 ) 新型磁纳米药物偶联体用于肿瘤多模式联合治疗及核磁共振成像研究, 负责人, 国家任务, 2011-01--2014-12