基本信息
龙勇 男 硕导 中国科学院水生生物研究所
电子邮件： longyong@ihb.ac.cn
通信地址： 湖北省武汉市武昌区东湖南路7号
邮政编码： 430072
电子邮件： longyong@ihb.ac.cn
通信地址： 湖北省武汉市武昌区东湖南路7号
邮政编码： 430072
招生信息
招生专业
071007-遗传学
招生方向
鱼类环境基因组学
教育背景
2007-09--2010-12 中国科学院水生生物研究所 博士
2002-09--2005-06 西南农业大学 硕士
1998-09--2002-06 西南农业大学 学士
2002-09--2005-06 西南农业大学 硕士
1998-09--2002-06 西南农业大学 学士
工作经历
工作简历
2015-12~2016-12,University of California, San Francisco, 访问学者
2013-12~现在, 中国科学院水生生物研究所, 副研究员
2011-01~2013-12,中国科学院水生生物研究所, 助理研究员
2005-07~2007-08,信阳农业高等专科学校, 助教
2013-12~现在, 中国科学院水生生物研究所, 副研究员
2011-01~2013-12,中国科学院水生生物研究所, 助理研究员
2005-07~2007-08,信阳农业高等专科学校, 助教
专利与奖励
专利成果
[1] 龙勇, 刘冉, 宋桂丽, 李青, 崔宗斌. 一株吉富罗非鱼脑神经细胞系、转染方法、培养方法及其应用. CN: [[[CN111690613A]]], [[["2020-09-22"]]].
[2] 宋桂丽, 龙勇. 一种罗非鱼受精卵的人工孵化装置. CN: CN214801686U, 2021-11-23.
[3] 崔宗斌, 周同, 周波兰, 龙勇, 宋桂丽, 李青, 朱作言. 一种鱼类皮肤粘液腺生物反应器的制备方法及其应用. CN: CN110628818A, 2019-12-31.
[4] 宋桂丽, 刘春艳, 龙勇, 李青, 崔宗斌. 斑马鱼神经组织特异性增强子及其克隆和应用. CN: CN105087578A, 2015-11-25.
[2] 宋桂丽, 龙勇. 一种罗非鱼受精卵的人工孵化装置. CN: CN214801686U, 2021-11-23.
[3] 崔宗斌, 周同, 周波兰, 龙勇, 宋桂丽, 李青, 朱作言. 一种鱼类皮肤粘液腺生物反应器的制备方法及其应用. CN: CN110628818A, 2019-12-31.
[4] 宋桂丽, 刘春艳, 龙勇, 李青, 崔宗斌. 斑马鱼神经组织特异性增强子及其克隆和应用. CN: CN105087578A, 2015-11-25.
出版信息
发表论文
[1] Science of The Total Environment. 2024, 通讯作者
[2] Aquaculture. 2024, 通讯作者
[3] Zhicheng Xv, Shaoxiong Chen, Guili Song, Han Hu, Shimei Lin, Yong Long. Biochemical, histological and transcriptomic analyses for the immunological organs provide insights into heat stress-induced disease susceptibility in Largemouth Bass. SCIENCE OF THE TOTAL ENVIRONMENT. 2024, 第 6 作者 通讯作者 912: http://dx.doi.org/10.1016/j.scitotenv.2023.168758.
[4] Hu, Han, Long, Yong, Song, Guili, Chen, Shaoxiong, Xu, Zhicheng, Li, Qing, Wu, Zhengli. Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 第 2 作者 通讯作者 24(4): http://dx.doi.org/10.3390/ijms24043849.
[5] Juhong Xie, Long, Yong. Identification of male-specific DNA markers and generation of genetically all-female offspring using natural pseudomales in Amur catfish (Silurus asotus). Aquaculture[J]. 2023, 第 2 作者 通讯作者
[6] 崔宗斌, 任静, 龙勇. 鱼类低温应激和损伤的信号通路与调控机制. 河南师范大学学报:自然科学版. 2023, 第 3 作者51(3): 11-21+171, http://lib.cqvip.com/Qikan/Article/Detail?id=7109653608.
[7] Liu, Ran, Liu, Renyan, Song, Guili, Li, Qing, Cui, Zongbin, Long, Yong. Mitochondria Dysfunction and Cell Apoptosis Limit Resistance of Nile Tilapia (Oreochromis niloticus) to Lethal Cold Stress. ANIMALS[J]. 2022, 第 6 作者 通讯作者 12(18): http://dx.doi.org/10.3390/ani12182382.
[8] Liu, Renyan, Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Yan, Huawei, Cui, Zongbin. Understanding the Function and Mechanism of Zebrafish Tmem39b in Regulating Cold Resistance. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 第 2 作者 通讯作者 23(19): http://dx.doi.org/10.3390/ijms231911442.
[9] Ge, Guodong, Long, Yong, Song, Guili, Li, Qing, Cui, Zongbin, Yan, Huawei. Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 第 2 作者23(14):
[10] Li, Fengyang, Long, Yong, Xie, Juhong, Ren, Jing, Zhou, Tong, Song, Guili, Li, Qing, Cui, Zongbin. Generation of GCaMP6s-Expressing Zebrafish to Monitor Spatiotemporal Dynamics of Calcium Signaling Elicited by Heat Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者 通讯作者 22(11): http://dx.doi.org/10.3390/ijms22115551.
[11] Ren, Jing, Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Cui, Zongbin. Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者 通讯作者 22(6): https://doaj.org/article/229b1caf6ef942778fd1d6c0a6028ffa.
[12] Lu, Xing, Long, Yong, Li, Xixi, Zhang, Lang, Li, Qing, Wen, Hua, Zhong, Shan, Cui, Zongbin. Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者22(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923114/.
[13] Zhou, Tong, Zhou, Bolan, Zhao, Yasong, Li, Qing, Song, Guili, Zhu, Zuoyan, Long, Yong, Cui, Zongbin. Development of a Mucus Gland Bioreactor in Loach Paramisgurnus dabryanus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 7 作者 通讯作者 22(2): http://dx.doi.org/10.3390/ijms22020687.
[14] 龙勇, 葛国栋, 李西西, 崔宗斌. 鱼类低温应激反应的调控机制. 水生生物学报[J]. 2021, 第 1 作者45(6): 1405-1414, http://lib.cqvip.com/Qikan/Article/Detail?id=7106233785.
[15] Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Cui, Zongbin. Establishment and characterization of a cold-sensitive neural cell line from the brain of tilapia (Oreochromis niloticus). JOURNAL OF FISH BIOLOGY[J]. 2021, 第 1 作者 通讯作者 98(3): 842-854, http://dx.doi.org/10.1111/jfb.14637.
[16] Long, Yong, Li, Xixi, Li, Fengyang, Ge, Guodong, Liu, Ran, Song, Guili, Li, Qing, Qiao, Zhigang, Cui, Zongbin. Transcriptional Programs Underlying Cold Acclimation of Common Carp (Cyprinus carpioL.). FRONTIERS IN GENETICS[J]. 2020, 第 1 作者11: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538616/.
[17] Yan, Junjun, Long, Yong, Zhou, Tong, Ren, Jing, Li, Qing, Song, Guili, Cui, Zongbin. Dynamic Phosphoproteome Profiling of Zebrafish Embryonic Fibroblasts during Cold Acclimation. PROTEOMICS[J]. 2020, 第 2 作者20(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000506064600001.
[18] Shen, Fangfang, Long, Yong, Li, Fengyang, Ge, Guodong, Song, Guili, Li, Qing, Qiao, Zhigang, Cui, Zongbin. De novo transcriptome assembly and sex-biased gene expression in the gonads of Amur catfish (Silurus asotus). GENOMICS[J]. 2020, 第 2 作者112(3): 2603-2614, http://dx.doi.org/10.1016/j.ygeno.2020.01.026.
[19] Ge, Guodong, Long, Yong, Shi, Lianyu, Ren, Jing, Yan, Junjun, Li, Chitao, Li, Qing, Cui, Zongbin. Transcriptomic profiling revealed key signaling pathways for cold tolerance and acclimation of two carp species. BMC GENOMICS[J]. 2020, 第 2 作者 通讯作者 21(1): http://dx.doi.org/10.1186/s12864-020-06946-8.
[20] Vozdek, Roman, Long, Yong, Ma, Dengke K. The receptor tyrosine kinase HIR-1 coordinates HIF-independent responses to hypoxia and extracellular matrix injury. SCIENCE SIGNALING[J]. 2018, 第 2 作者11(550): http://dx.doi.org/10.1126/scisignal.aat0138.
[21] Wei Jiang. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans. ELIFE SCIENCES PUBLICATIONS, LTD. 2018, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201910289023843ZK.
[22] Jiang, Wei, Wei, Yuehua, Long, Yong, Owen, Arthur, Wang, Bingying, Wu, Xuebing, Luo, Shuo, Dang, Yongjun, Ma, Dengke K. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C-elegans. ELIFE[J]. 2018, 第 3 作者7: https://doaj.org/article/d57a8eae22bf44a185594635bba730c7.
[23] Yan, Junjun, Gao, Qiang, Cui, Zongbin, Yang, Guoliang, Long, Yong. Molecular characterization of the giant freshwater prawn (Macrobrachium rosenbergii) beta-actin gene promoter. PEERJ[J]. 2018, 第 5 作者 通讯作者 6: http://202.127.146.157/handle/2RYDP1HH/5852.
[24] Wu, DongMei, Ma, LiangPeng, Song, GuiLi, Long, Yong, Liu, HanXiao, Liu, Yang, Ping, Jie. Steroidogenic factor-1 hypermethylation in maternal rat blood could serve as a biomarker for intrauterine growth retardation. ONCOTARGET[J]. 2017, 第 4 作者8(56): 96139-96153, https://www.webofscience.com/wos/woscc/full-record/WOS:000414937900086.
[25] Li, Zhouquan, Long, Yong, Zhong, Liqiao, Song, Guili, Zhang, Xiaohua, Yuan, Li, Cui, Zongbin, Dai, Heping. RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate. JOURNAL OF APPLIED TOXICOLOGY[J]. 2016, 第 2 作者36(1): 94-104, http://dx.doi.org/10.1002/jat.3147.
[26] Zhou, Bolan, Long, Yong, Song, Guili, Li, Qing, Cui, Zongbin. Molecular characterization of the lgals1 gene in large scale loach Paramisgurnus dabryanus. GENE[J]. 2016, 第 2 作者 通讯作者 577(1): 65-74, http://dx.doi.org/10.1016/j.gene.2015.11.025.
[27] Long, Yong, Yan, Junjun, Song, Guili, Li, Xiaohui, Li, Xixi, Li, Qing, Cui, Zongbin. Transcriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvae. BMC GENOMICS[J]. 2015, 第 1 作者16(1): http://www.irgrid.ac.cn/handle/1471x/978676.
[28] Feng, Guohui, Long, Yong, Peng, Jinrong, Li, Qing, Cui, Zongbin. Transcriptomic characterization of the dorsal lobes after hepatectomy of the ventral lobe in zebrafish. BMC GENOMICS[J]. 2015, 第 2 作者16(1): http://www.irgrid.ac.cn/handle/1471x/1012143.
[29] Liu, Chunyan, Song, Guili, Mao, Lin, Long, Yong, Li, Qing, Cui, Zongbin. Generation of an Enhancer-Trapping Vector for Insertional Mutagenesis in Zebrafish. PLOS ONE[J]. 2015, 第 4 作者10(10): http://www.irgrid.ac.cn/handle/1471x/991727.
[30] Lu, Xing, Long, Yong, Sun, Rongze, Zhou, Bolan, Lin, Li, Zhong, Shan, Cui, Zongbin. Zebrafish Abcb4 is a potential efflux transporter of microcystin-LR. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2015, 第 2 作者167: 35-42, http://dx.doi.org/10.1016/j.cbpc.2014.08.005.
[31] Zhong, Liqiao, Yuan, Li, Rao, Yu, Li, Zhouquan, Gu, Qilin, Long, Yong, Zhang, Xiaohua, Cui, Zongbin, Xu, Ying, Dai, Heping. Investigation of effect of 17 alpha-ethinylestradiol on vigilin expression using an isolated recombinant antibody. AQUATIC TOXICOLOGY[J]. 2014, 第 6 作者156: 1-9, http://www.irgrid.ac.cn/handle/1471x/929264.
[32] Liqiao Zhong, Li Yuan, Yu Rao, Zhouquan Li, Qilin Gu, Yong Long, Xiaohua Zhang, Zongbin Cui, Ying Xu, Heping Dai. Investigation of effect of 17α-ethinylestradiol on vigilin expression using an isolated recombinant antibody. AQUATIC TOXICOLOGY. 2014, 第 6 作者156: 1-9, http://dx.doi.org/10.1016/j.aquatox.2014.07.016.
[33] 杨玲, 严军军, 龙勇, 崔宗斌, 鲍传和. 斑马鱼nr1d4a和nr1d4b基因的表达及其对不同环境刺激的响应. 水生生物学报[J]. 2014, 第 3 作者38(1): 100-107, http://lib.cqvip.com/Qikan/Article/Detail?id=48542919.
[34] Lu, Xing, Long, Yong, Lin, Li, Sun, Rongze, Zhong, Shan, Cui, Zongbin. Characterization of Zebrafish Abcc4 as an Efflux Transporter of Organochlorine Pesticides. PLOS ONE[J]. 2014, 第 2 作者9(12): http://dx.doi.org/10.1371/journal.pone.0111664.
[35] He, Xiaozhen, Li, Jie, Long, Yong, Song, Guili, Zhou, Peiyong, Liu, Qiuxiang, Zhu, Zuoyan, Cui, Zongbin. Gene transfer and mutagenesis mediated by Sleeping Beauty transposon in Nile tilapia (Oreochromis niloticus). TRANSGENIC RESEARCH[J]. 2013, 第 3 作者22(5): 913-924, http://dx.doi.org/10.1007/s11248-013-9693-8.
[36] Long, Yong, Li, Qing, Zhou, Bolan, Song, Guili, Li, Tao, Cui, Zongbin. De Novo Assembly of Mud Loach (Misgurnus anguillicaudatus) Skin Transcriptome to Identify Putative Genes Involved in Immunity and Epidermal Mucus Secretion. PLOS ONE[J]. 2013, 第 1 作者8(2): http://www.irgrid.ac.cn/handle/1471x/733514.
[37] Long, Yong, Song, Guili, Yan, Junjun, He, Xiaozhen, Li, Qing, Cui, Zongbin. Transcriptomic characterization of cold acclimation in larval zebrafish. BMC GENOMICS[J]. 2013, 第 1 作者14(1): 612-612, http://www.irgrid.ac.cn/handle/1471x/779919.
[38] Song, Guili, Li, Qing, Long, Yong, Gu, Qilin, Hackett, Perry B, Cui, Zongbin. Effective Gene Trapping Mediated by Sleeping Beauty Transposon. PLOS ONE[J]. 2012, 第 3 作者7(8): http://www.irgrid.ac.cn/handle/1471x/533469.
[39] 李林春, 李青, 龙勇, 崔宗斌. 温度刺激对斑马鱼仔鱼基因转录表达的影响. 水生生物学报[J]. 2012, 第 3 作者36(5): 882-891, http://lib.cqvip.com/Qikan/Article/Detail?id=43590027.
[40] Long, Yong, Li, Linchun, Li, Qing, He, Xiaozhen, Cui, Zongbin. Transcriptomic Characterization of Temperature Stress Responses in Larval Zebrafish. PLOS ONE[J]. 2012, 第 1 作者 通讯作者 7(5): https://doaj.org/article/d76f6c13310d4c2a827a45ac07714891.
[41] Song, Guili, Li, Qing, Long, Yong, Hackett, Perry B, Cui, Zongbin. Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon. JOURNAL OF GENETICS AND GENOMICS[J]. 2012, 第 3 作者39(9): 503-520, http://lib.cqvip.com/Qikan/Article/Detail?id=43433735.
[42] Li, Yuanyuan, Li, Qing, Long, Yong, Cui, Zongbin. Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear beta-Catenin in Zebrafish. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2011, 第 3 作者286(52): 45116-45130, http://www.irgrid.ac.cn/handle/1471x/1759727.
[43] Long, Yong, Li, Qing, Zhong, Shan, Wang, Youhui, Cui, Zongbin. Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2011, 第 1 作者153(4): 381-391, http://dx.doi.org/10.1016/j.cbpc.2011.01.002.
[44] Yong Long, Qing Li, Jie Li, Zongbin Cui. Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART B. 2011, 第 1 作者158(1): 46-55, http://dx.doi.org/10.1016/j.cbpb.2010.09.005.
[45] Yong Long, Qing Li, Youhui Wang, Zongbin Cui. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART C. 2011, 第 1 作者153(3): 310-317, http://dx.doi.org/10.1016/j.cbpc.2010.12.001.
[46] Long, Yong, Li, Qing, Cui, Zongbin. Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish. MOLECULAR BIOLOGY REPORTS[J]. 2011, 第 1 作者38(3): 1703-1711, https://www.webofscience.com/wos/woscc/full-record/WOS:000286941400033.
[47] Long, Yong, Li, Qing, Wang, Youhui, Cui, Zongbin. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2011, 第 1 作者153(3): 310-317, http://dx.doi.org/10.1016/j.cbpc.2010.12.001.
[48] Yong Long, Qing Li, Shan Zhong, Youhui Wang, Zongbin Cui. Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART C. 2011, 第 1 作者153(4): 381-391, http://dx.doi.org/10.1016/j.cbpc.2011.01.002.
[49] Yuanyuan Li, Qing Li, Yong Long, Zongbin Cui. Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish*. JOURNAL OF BIOLOGICAL CHEMISTRY. 2011, 第 3 作者286(52): 45116-45130, http://dx.doi.org/10.1074/jbc.M111.267328.
[50] Long, Yong, Li, Qing, Li, Jie, Cui, Zongbin. Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2011, 第 1 作者158(1): 46-55, http://dx.doi.org/10.1016/j.cbpb.2010.09.005.
[51] 龙勇. 斑马鱼多药耐药相关蛋白基因的克隆、表达和功能研究. 2010, 第 1 作者129, http://ir.ihb.ac.cn/handle/342005/11915.
[52] Pei, DeSheng, Sun, YongHua, Long, Yong, Zhu, ZuoYan. Inhibition of no tail (ntl) gene expression in zebrafish by external guide sequence (EGS) technique. MOLECULAR BIOLOGY REPORTS[J]. 2008, 第 3 作者35(2): 139-143, http://ir.ihb.ac.cn/handle/152342/8114.
[2] Aquaculture. 2024, 通讯作者
[3] Zhicheng Xv, Shaoxiong Chen, Guili Song, Han Hu, Shimei Lin, Yong Long. Biochemical, histological and transcriptomic analyses for the immunological organs provide insights into heat stress-induced disease susceptibility in Largemouth Bass. SCIENCE OF THE TOTAL ENVIRONMENT. 2024, 第 6 作者 通讯作者 912: http://dx.doi.org/10.1016/j.scitotenv.2023.168758.
[4] Hu, Han, Long, Yong, Song, Guili, Chen, Shaoxiong, Xu, Zhicheng, Li, Qing, Wu, Zhengli. Dysfunction of Prkcaa Links Social Behavior Defects with Disturbed Circadian Rhythm in Zebrafish. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2023, 第 2 作者 通讯作者 24(4): http://dx.doi.org/10.3390/ijms24043849.
[5] Juhong Xie, Long, Yong. Identification of male-specific DNA markers and generation of genetically all-female offspring using natural pseudomales in Amur catfish (Silurus asotus). Aquaculture[J]. 2023, 第 2 作者 通讯作者
[6] 崔宗斌, 任静, 龙勇. 鱼类低温应激和损伤的信号通路与调控机制. 河南师范大学学报:自然科学版. 2023, 第 3 作者51(3): 11-21+171, http://lib.cqvip.com/Qikan/Article/Detail?id=7109653608.
[7] Liu, Ran, Liu, Renyan, Song, Guili, Li, Qing, Cui, Zongbin, Long, Yong. Mitochondria Dysfunction and Cell Apoptosis Limit Resistance of Nile Tilapia (Oreochromis niloticus) to Lethal Cold Stress. ANIMALS[J]. 2022, 第 6 作者 通讯作者 12(18): http://dx.doi.org/10.3390/ani12182382.
[8] Liu, Renyan, Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Yan, Huawei, Cui, Zongbin. Understanding the Function and Mechanism of Zebrafish Tmem39b in Regulating Cold Resistance. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 第 2 作者 通讯作者 23(19): http://dx.doi.org/10.3390/ijms231911442.
[9] Ge, Guodong, Long, Yong, Song, Guili, Li, Qing, Cui, Zongbin, Yan, Huawei. Transcriptomic Profiling Revealed Signaling Pathways Associated with the Spawning of Female Zebrafish under Cold Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 第 2 作者23(14):
[10] Li, Fengyang, Long, Yong, Xie, Juhong, Ren, Jing, Zhou, Tong, Song, Guili, Li, Qing, Cui, Zongbin. Generation of GCaMP6s-Expressing Zebrafish to Monitor Spatiotemporal Dynamics of Calcium Signaling Elicited by Heat Stress. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者 通讯作者 22(11): http://dx.doi.org/10.3390/ijms22115551.
[11] Ren, Jing, Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Cui, Zongbin. Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者 通讯作者 22(6): https://doaj.org/article/229b1caf6ef942778fd1d6c0a6028ffa.
[12] Lu, Xing, Long, Yong, Li, Xixi, Zhang, Lang, Li, Qing, Wen, Hua, Zhong, Shan, Cui, Zongbin. Generation of Knockout and Transgenic Zebrafish to Characterize Abcc4 Functions in Detoxification and Efflux of Lead. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 2 作者22(4): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7923114/.
[13] Zhou, Tong, Zhou, Bolan, Zhao, Yasong, Li, Qing, Song, Guili, Zhu, Zuoyan, Long, Yong, Cui, Zongbin. Development of a Mucus Gland Bioreactor in Loach Paramisgurnus dabryanus. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2021, 第 7 作者 通讯作者 22(2): http://dx.doi.org/10.3390/ijms22020687.
[14] 龙勇, 葛国栋, 李西西, 崔宗斌. 鱼类低温应激反应的调控机制. 水生生物学报[J]. 2021, 第 1 作者45(6): 1405-1414, http://lib.cqvip.com/Qikan/Article/Detail?id=7106233785.
[15] Long, Yong, Liu, Ran, Song, Guili, Li, Qing, Cui, Zongbin. Establishment and characterization of a cold-sensitive neural cell line from the brain of tilapia (Oreochromis niloticus). JOURNAL OF FISH BIOLOGY[J]. 2021, 第 1 作者 通讯作者 98(3): 842-854, http://dx.doi.org/10.1111/jfb.14637.
[16] Long, Yong, Li, Xixi, Li, Fengyang, Ge, Guodong, Liu, Ran, Song, Guili, Li, Qing, Qiao, Zhigang, Cui, Zongbin. Transcriptional Programs Underlying Cold Acclimation of Common Carp (Cyprinus carpioL.). FRONTIERS IN GENETICS[J]. 2020, 第 1 作者11: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7538616/.
[17] Yan, Junjun, Long, Yong, Zhou, Tong, Ren, Jing, Li, Qing, Song, Guili, Cui, Zongbin. Dynamic Phosphoproteome Profiling of Zebrafish Embryonic Fibroblasts during Cold Acclimation. PROTEOMICS[J]. 2020, 第 2 作者20(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000506064600001.
[18] Shen, Fangfang, Long, Yong, Li, Fengyang, Ge, Guodong, Song, Guili, Li, Qing, Qiao, Zhigang, Cui, Zongbin. De novo transcriptome assembly and sex-biased gene expression in the gonads of Amur catfish (Silurus asotus). GENOMICS[J]. 2020, 第 2 作者112(3): 2603-2614, http://dx.doi.org/10.1016/j.ygeno.2020.01.026.
[19] Ge, Guodong, Long, Yong, Shi, Lianyu, Ren, Jing, Yan, Junjun, Li, Chitao, Li, Qing, Cui, Zongbin. Transcriptomic profiling revealed key signaling pathways for cold tolerance and acclimation of two carp species. BMC GENOMICS[J]. 2020, 第 2 作者 通讯作者 21(1): http://dx.doi.org/10.1186/s12864-020-06946-8.
[20] Vozdek, Roman, Long, Yong, Ma, Dengke K. The receptor tyrosine kinase HIR-1 coordinates HIF-independent responses to hypoxia and extracellular matrix injury. SCIENCE SIGNALING[J]. 2018, 第 2 作者11(550): http://dx.doi.org/10.1126/scisignal.aat0138.
[21] Wei Jiang. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C. elegans. ELIFE SCIENCES PUBLICATIONS, LTD. 2018, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201910289023843ZK.
[22] Jiang, Wei, Wei, Yuehua, Long, Yong, Owen, Arthur, Wang, Bingying, Wu, Xuebing, Luo, Shuo, Dang, Yongjun, Ma, Dengke K. A genetic program mediates cold-warming response and promotes stress-induced phenoptosis in C-elegans. ELIFE[J]. 2018, 第 3 作者7: https://doaj.org/article/d57a8eae22bf44a185594635bba730c7.
[23] Yan, Junjun, Gao, Qiang, Cui, Zongbin, Yang, Guoliang, Long, Yong. Molecular characterization of the giant freshwater prawn (Macrobrachium rosenbergii) beta-actin gene promoter. PEERJ[J]. 2018, 第 5 作者 通讯作者 6: http://202.127.146.157/handle/2RYDP1HH/5852.
[24] Wu, DongMei, Ma, LiangPeng, Song, GuiLi, Long, Yong, Liu, HanXiao, Liu, Yang, Ping, Jie. Steroidogenic factor-1 hypermethylation in maternal rat blood could serve as a biomarker for intrauterine growth retardation. ONCOTARGET[J]. 2017, 第 4 作者8(56): 96139-96153, https://www.webofscience.com/wos/woscc/full-record/WOS:000414937900086.
[25] Li, Zhouquan, Long, Yong, Zhong, Liqiao, Song, Guili, Zhang, Xiaohua, Yuan, Li, Cui, Zongbin, Dai, Heping. RNA sequencing provides insights into the toxicogenomic response of ZF4 cells to methyl methanesulfonate. JOURNAL OF APPLIED TOXICOLOGY[J]. 2016, 第 2 作者36(1): 94-104, http://dx.doi.org/10.1002/jat.3147.
[26] Zhou, Bolan, Long, Yong, Song, Guili, Li, Qing, Cui, Zongbin. Molecular characterization of the lgals1 gene in large scale loach Paramisgurnus dabryanus. GENE[J]. 2016, 第 2 作者 通讯作者 577(1): 65-74, http://dx.doi.org/10.1016/j.gene.2015.11.025.
[27] Long, Yong, Yan, Junjun, Song, Guili, Li, Xiaohui, Li, Xixi, Li, Qing, Cui, Zongbin. Transcriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvae. BMC GENOMICS[J]. 2015, 第 1 作者16(1): http://www.irgrid.ac.cn/handle/1471x/978676.
[28] Feng, Guohui, Long, Yong, Peng, Jinrong, Li, Qing, Cui, Zongbin. Transcriptomic characterization of the dorsal lobes after hepatectomy of the ventral lobe in zebrafish. BMC GENOMICS[J]. 2015, 第 2 作者16(1): http://www.irgrid.ac.cn/handle/1471x/1012143.
[29] Liu, Chunyan, Song, Guili, Mao, Lin, Long, Yong, Li, Qing, Cui, Zongbin. Generation of an Enhancer-Trapping Vector for Insertional Mutagenesis in Zebrafish. PLOS ONE[J]. 2015, 第 4 作者10(10): http://www.irgrid.ac.cn/handle/1471x/991727.
[30] Lu, Xing, Long, Yong, Sun, Rongze, Zhou, Bolan, Lin, Li, Zhong, Shan, Cui, Zongbin. Zebrafish Abcb4 is a potential efflux transporter of microcystin-LR. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2015, 第 2 作者167: 35-42, http://dx.doi.org/10.1016/j.cbpc.2014.08.005.
[31] Zhong, Liqiao, Yuan, Li, Rao, Yu, Li, Zhouquan, Gu, Qilin, Long, Yong, Zhang, Xiaohua, Cui, Zongbin, Xu, Ying, Dai, Heping. Investigation of effect of 17 alpha-ethinylestradiol on vigilin expression using an isolated recombinant antibody. AQUATIC TOXICOLOGY[J]. 2014, 第 6 作者156: 1-9, http://www.irgrid.ac.cn/handle/1471x/929264.
[32] Liqiao Zhong, Li Yuan, Yu Rao, Zhouquan Li, Qilin Gu, Yong Long, Xiaohua Zhang, Zongbin Cui, Ying Xu, Heping Dai. Investigation of effect of 17α-ethinylestradiol on vigilin expression using an isolated recombinant antibody. AQUATIC TOXICOLOGY. 2014, 第 6 作者156: 1-9, http://dx.doi.org/10.1016/j.aquatox.2014.07.016.
[33] 杨玲, 严军军, 龙勇, 崔宗斌, 鲍传和. 斑马鱼nr1d4a和nr1d4b基因的表达及其对不同环境刺激的响应. 水生生物学报[J]. 2014, 第 3 作者38(1): 100-107, http://lib.cqvip.com/Qikan/Article/Detail?id=48542919.
[34] Lu, Xing, Long, Yong, Lin, Li, Sun, Rongze, Zhong, Shan, Cui, Zongbin. Characterization of Zebrafish Abcc4 as an Efflux Transporter of Organochlorine Pesticides. PLOS ONE[J]. 2014, 第 2 作者9(12): http://dx.doi.org/10.1371/journal.pone.0111664.
[35] He, Xiaozhen, Li, Jie, Long, Yong, Song, Guili, Zhou, Peiyong, Liu, Qiuxiang, Zhu, Zuoyan, Cui, Zongbin. Gene transfer and mutagenesis mediated by Sleeping Beauty transposon in Nile tilapia (Oreochromis niloticus). TRANSGENIC RESEARCH[J]. 2013, 第 3 作者22(5): 913-924, http://dx.doi.org/10.1007/s11248-013-9693-8.
[36] Long, Yong, Li, Qing, Zhou, Bolan, Song, Guili, Li, Tao, Cui, Zongbin. De Novo Assembly of Mud Loach (Misgurnus anguillicaudatus) Skin Transcriptome to Identify Putative Genes Involved in Immunity and Epidermal Mucus Secretion. PLOS ONE[J]. 2013, 第 1 作者8(2): http://www.irgrid.ac.cn/handle/1471x/733514.
[37] Long, Yong, Song, Guili, Yan, Junjun, He, Xiaozhen, Li, Qing, Cui, Zongbin. Transcriptomic characterization of cold acclimation in larval zebrafish. BMC GENOMICS[J]. 2013, 第 1 作者14(1): 612-612, http://www.irgrid.ac.cn/handle/1471x/779919.
[38] Song, Guili, Li, Qing, Long, Yong, Gu, Qilin, Hackett, Perry B, Cui, Zongbin. Effective Gene Trapping Mediated by Sleeping Beauty Transposon. PLOS ONE[J]. 2012, 第 3 作者7(8): http://www.irgrid.ac.cn/handle/1471x/533469.
[39] 李林春, 李青, 龙勇, 崔宗斌. 温度刺激对斑马鱼仔鱼基因转录表达的影响. 水生生物学报[J]. 2012, 第 3 作者36(5): 882-891, http://lib.cqvip.com/Qikan/Article/Detail?id=43590027.
[40] Long, Yong, Li, Linchun, Li, Qing, He, Xiaozhen, Cui, Zongbin. Transcriptomic Characterization of Temperature Stress Responses in Larval Zebrafish. PLOS ONE[J]. 2012, 第 1 作者 通讯作者 7(5): https://doaj.org/article/d76f6c13310d4c2a827a45ac07714891.
[41] Song, Guili, Li, Qing, Long, Yong, Hackett, Perry B, Cui, Zongbin. Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon. JOURNAL OF GENETICS AND GENOMICS[J]. 2012, 第 3 作者39(9): 503-520, http://lib.cqvip.com/Qikan/Article/Detail?id=43433735.
[42] Li, Yuanyuan, Li, Qing, Long, Yong, Cui, Zongbin. Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear beta-Catenin in Zebrafish. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2011, 第 3 作者286(52): 45116-45130, http://www.irgrid.ac.cn/handle/1471x/1759727.
[43] Long, Yong, Li, Qing, Zhong, Shan, Wang, Youhui, Cui, Zongbin. Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2011, 第 1 作者153(4): 381-391, http://dx.doi.org/10.1016/j.cbpc.2011.01.002.
[44] Yong Long, Qing Li, Jie Li, Zongbin Cui. Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART B. 2011, 第 1 作者158(1): 46-55, http://dx.doi.org/10.1016/j.cbpb.2010.09.005.
[45] Yong Long, Qing Li, Youhui Wang, Zongbin Cui. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART C. 2011, 第 1 作者153(3): 310-317, http://dx.doi.org/10.1016/j.cbpc.2010.12.001.
[46] Long, Yong, Li, Qing, Cui, Zongbin. Molecular analysis and heavy metal detoxification of ABCC1/MRP1 in zebrafish. MOLECULAR BIOLOGY REPORTS[J]. 2011, 第 1 作者38(3): 1703-1711, https://www.webofscience.com/wos/woscc/full-record/WOS:000286941400033.
[47] Long, Yong, Li, Qing, Wang, Youhui, Cui, Zongbin. MRP proteins as potential mediators of heavy metal resistance in zebrafish cells. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY[J]. 2011, 第 1 作者153(3): 310-317, http://dx.doi.org/10.1016/j.cbpc.2010.12.001.
[48] Yong Long, Qing Li, Shan Zhong, Youhui Wang, Zongbin Cui. Molecular characterization and functions of zebrafish ABCC2 in cellular efflux of heavy metals. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY, PART C. 2011, 第 1 作者153(4): 381-391, http://dx.doi.org/10.1016/j.cbpc.2011.01.002.
[49] Yuanyuan Li, Qing Li, Yong Long, Zongbin Cui. Lzts2 Regulates Embryonic Cell Movements and Dorsoventral Patterning through Interaction with and Export of Nuclear β-Catenin in Zebrafish*. JOURNAL OF BIOLOGICAL CHEMISTRY. 2011, 第 3 作者286(52): 45116-45130, http://dx.doi.org/10.1074/jbc.M111.267328.
[50] Long, Yong, Li, Qing, Li, Jie, Cui, Zongbin. Molecular analysis, developmental function and heavy metal-induced expression of ABCC5 in zebrafish. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY[J]. 2011, 第 1 作者158(1): 46-55, http://dx.doi.org/10.1016/j.cbpb.2010.09.005.
[51] 龙勇. 斑马鱼多药耐药相关蛋白基因的克隆、表达和功能研究. 2010, 第 1 作者129, http://ir.ihb.ac.cn/handle/342005/11915.
[52] Pei, DeSheng, Sun, YongHua, Long, Yong, Zhu, ZuoYan. Inhibition of no tail (ntl) gene expression in zebrafish by external guide sequence (EGS) technique. MOLECULAR BIOLOGY REPORTS[J]. 2008, 第 3 作者35(2): 139-143, http://ir.ihb.ac.cn/handle/152342/8114.
科研活动
科研项目
（ 1 ） 斑马鱼抗寒相关转录因子的基因转移及其作用机制研究, 主持, 国家级, 2012-01--2014-12
（ 2 ） 罗氏沼虾抗病基因工程育种技术研究, 主持, 省级, 2013-01--2015-12
（ 3 ） 即刻早期基因在斑马鱼低温信号传导中的功能与机制研究, 主持, 市地级, 2015-01--2015-12
（ 4 ） 泥鳅皮肤粘液腺生物反应器的技术建立与应用研究, 主持, 市地级, 2012-01--2013-12
（ 5 ） 肝脏发育和再生关键基因的鉴定及遗传调控研究, 主持, 国家级, 2012-01--2016-12
（ 6 ） 从母体外周血中探寻宫内发育迟缓的DNA甲基化生物标志物研究, 主持, 国家级, 2013-01--2016-12
（ 7 ） Fos家族即刻早期基因在斑马鱼低温适应中的功能与机制研究, 主持, 国家级, 2016-01--2019-12
（ 8 ） 钙离子信号系统调控鱼类低温适应的分子机制研究, 主持, 国家级, 2018-01--2021-12
（ 9 ） 罗非鱼抗寒性状的分子基础, 主持, 国家级, 2018-12--2022-12
（ 2 ） 罗氏沼虾抗病基因工程育种技术研究, 主持, 省级, 2013-01--2015-12
（ 3 ） 即刻早期基因在斑马鱼低温信号传导中的功能与机制研究, 主持, 市地级, 2015-01--2015-12
（ 4 ） 泥鳅皮肤粘液腺生物反应器的技术建立与应用研究, 主持, 市地级, 2012-01--2013-12
（ 5 ） 肝脏发育和再生关键基因的鉴定及遗传调控研究, 主持, 国家级, 2012-01--2016-12
（ 6 ） 从母体外周血中探寻宫内发育迟缓的DNA甲基化生物标志物研究, 主持, 国家级, 2013-01--2016-12
（ 7 ） Fos家族即刻早期基因在斑马鱼低温适应中的功能与机制研究, 主持, 国家级, 2016-01--2019-12
（ 8 ） 钙离子信号系统调控鱼类低温适应的分子机制研究, 主持, 国家级, 2018-01--2021-12
（ 9 ） 罗非鱼抗寒性状的分子基础, 主持, 国家级, 2018-12--2022-12
参与会议
（1）斑马鱼抗寒相关信号通路的鉴定和功能研究 第十届水产生物技术专业委员会 2020-12-03
（2）即刻早期基因调控斑马鱼低温适应的作用机制研究 第九届水产生物技术专业委员会 2018-10-15
（3）Genetic programs underlying cold acclimation of zebrafish larvae 第十三届国际斑马鱼大会 2018-06-20
（4）Transcriptional regulation of cold acclimation in zebrafish 第十一届国际斑马鱼发育与遗传学大会 Yong Long and Zongbin Cui 2014-06-24
（2）即刻早期基因调控斑马鱼低温适应的作用机制研究 第九届水产生物技术专业委员会 2018-10-15
（3）Genetic programs underlying cold acclimation of zebrafish larvae 第十三届国际斑马鱼大会 2018-06-20
（4）Transcriptional regulation of cold acclimation in zebrafish 第十一届国际斑马鱼发育与遗传学大会 Yong Long and Zongbin Cui 2014-06-24
指导学生
现指导学生
陈艺元 硕士研究生 085238-生物工程
谢巨洪 硕士研究生 086000-生物与医药