070304-物理化学

电子顺磁共振，自由基

2006-09--2009-07   中国科学院化学研究所   博士研究生
2003-09--2006-07   大连理工大学   硕士研究生
1999-09--2003-07   山东理工大学   学士

   

2014-03~现在, 中国科学院化学研究所, 副研究员
2009-07~2014-02,中国科学院化学研究所, 助理研究员
2006-09~2009-07,中国科学院化学研究所, 博士研究生
2003-09~2006-07,大连理工大学, 硕士研究生
1999-09~2003-07,山东理工大学, 学士

   

（1） Oxygen vacancy in CoO/reduced graphene oxide composite for enhancing long-term effectiveness of photocatalytic CO 2 reduction via mediating exciton, 2D MATERIALS, 2024, 第 2 作者
（2） Extraction and study on the active componebts of xanthium sibiricum patrin, BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2021, 第 3 作者
（3） Exposure to PM2.5 aggravates Parkinson���s disease via inhibition of autophagy and mitophagy pathway, TOXICOLOGY, 2021, 第 11 作者  通讯作者
（4） A dual-functional nanovehicle with fluorescent tracking and its targeted killing effects on hepatocellular carcinoma cells, RSC ADVANCES, 2021, 第 6 作者
（5） Enhanced Neuroprotective Effects of Epicatechin Gallate Encapsulated by Bovine Milk-Derived Exosomes against Parkinson's Disease through Antiapoptosis and Antimitophagy, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021, 第 5 作者  通讯作者
（6） Surface Functionalization of Pegylated Gold Nanoparticles with Antioxidants Suppresses Nanoparticle-Induced Oxidative Stress and Neurotoxicity, CHEMICAL RESEARCH IN TOXICOLOGY, 2020, 第 8 作者  通讯作者
（7） Potential Therapeutic Applications and Developments of Exosomes in Parkinson's Disease, MOLECULAR PHARMACEUTICS, 2020, 第 2 作者
（8） A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery, A reactive oxygen species-responsive dendrimer with low cytotoxicity for efficient and targeted gene delivery, CHINESE CHEMICAL LETTERS, 2020, 第 3 作者  通讯作者
（9） Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation, ACS NANO, 2020, 第 2 作者
（10） Phosphinate-based mitochondria-targeted fluorescent probe for imaging and detection of endogenous superoxide in live cells and in vivo, TALANTA, 2019, 第 8 作者  通讯作者
（11） Sensitive detection and imaging of endogenous peroxynitrite using a benzo d thiazole derived cyanine probe, TALANTA, 2019, 第 5 作者
（12） P-335 - Phosphinate-based mitochondria targeted fluorescent probe for in vitro and in vivo detection of superoxide anion, FREE RADICAL BIOLOGY AND MEDICINE, 2018, 第 4 作者
（13） Nano-oleanolic acid alleviates metabolic dysfunctions in rats with high fat and fructose diet, BIOMEDICINE & PHARMACOTHERAPY, 2018, 第 2 作者
（14） Multi-functionalized chitosan nanoparticles for enhanced chemotherapy in lung cancer, CARBOHYDRATE POLYMERS, 2018, 第 10 作者  通讯作者
（15） tert -Butylhydroperoxide induces apoptosis in RAW264.7 macrophages via a mitochondria-mediated signaling pathway, TOXICOLOGY RESEARCH, 2018, 第 6 作者  通讯作者
（16） Murine exposure to gold nanoparticles during early pregnancy promotes abortion by inhibiting ectodermal differentiation, MOLECULAR MEDICINE, 2018, 第 2 作者
（17） Red fluorescent carbon dots with phenylboronic acid tags for quick detection of Fe(III) in PC12 cells, JOURNAL OF COLLOID AND INTERFACE SCIENCE, 2018, 第 6 作者  通讯作者
（18） A photostable fluorescent probe for long-time imagining of lysosome in cell and nematode, TALANTA, 2018, 第 9 作者  通讯作者
（19） A facile synthesis of biocompatible, glycol chitosan shelled CdSeS/ZnS QDs for live cell imaging, COLLOIDS AND SURFACES B-BIOINTERFACES, 2018, 第 5 作者
（20） P-336 - Enhanced antioxidants activity of antioxidants through surface self-assembly approach, FREE RADICAL BIOLOGY AND MEDICINE, 2018, 第 1 作者
（21） Novel nano antioxidant drug delivery systems for the treatment of neurodegenerative diseases, FREE RADICAL BIOLOGY AND MEDICINE, 2018, 第 2 作者
（22） Sensitive determination of endogenous hydroxyl radical in live cell by a BODIPY based fluorescent probe, TALANTA, 2017, 第 3 作者
（23） An intramolecular charge transfer process based fluorescent probe for monitoring subtle pH fluctuation in living cells, TALANTA, 2017, 第 2 作者
（24） A ratiometric fluorescent probe based on the pi-stacked graphene oxide and cyanine dye for sensitive detection of bisulfiteHuan, SENSORS AND ACTUATORS B-CHEMICAL, 2017, 第 2 作者
（25） A ratiometric fluorescent probe based on the pi-stacked graphene oxide and cyanine dye for sensitive detection of bisulfite, SENSORS & ACTUATORS: B. CHEMICAL, 2017, 第 2 作者
（26） The alternative strategy for designing covalent drugs through kinetic effects of pi-stacking on the self-assembled nanoparticles: a model study with antibiotics, NANOTECHNOLOGY, 2016, 第 1 作者
（27） Reversible Fluorescent Probe for Selective Detection and Cell Imaging of Oxidative Stress Indicator Bisulfite, ANALYTICAL CHEMISTRY, 2016, 第 5 作者
（28） New Tanshinone IIA Delivery System Using Chitosan Nanomicelles of Small Size, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2016, 第 2 作者
（29） 小尺寸低聚壳聚糖/丹参酮ⅡA纳米载药体系, New Tanshinone ���A Delivery System Using Chitosan Nanomicelles of Small Size���, 高等学校化学学报, 2016, 第 2 作者
（30） L-精氨酸和天然抗氧化剂对缺血性脑卒中防治作用的细胞和动物模型研究, Preventive and Therapeutic Effects of L-Arginine and Natural Antioxidants on Ischemic Stroke in Cell and Animal Models, 心脑血管病防治, 2016, 第 3 作者
（31） A New Nano Antioxidant Prevention and Therapy Delivery System, FREE RADICAL BIOLOGY AND MEDICINE, 2016, 第 2 作者
（32） New Tanshinone IIA Delivery System Using Chitosan Nanomicelles of Small Size, CHEMICALJOURNALOFCHINESEUNIVERSITIESCHINESE, 2016, 第 2 作者
（33） Low cytotoxicity fluorescent PAMAM dendrimer as gene carriers for monitoring the delivery of siRNA, JOURNAL OF NANOPARTICLE RESEARCH, 2015, 第 7 作者  通讯作者
（34） Tanshinone II A, a multiple target neuroprotectant, promotes caveolae-dependent neuronal, EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 第 4 作者
（35） New photostable naphthalimide-based fluorescent probe for mitochondrial imaging and tracking, BIOSENSORS & BIOELECTRONICS, 2015, 第 4 作者  通讯作者
（36） Tanshinone II A, a multiple target neuroprotectant, promotes caveolae-dependent neuronal differentiation, EUROPEAN JOURNAL OF PHARMACOLOGY, 2015, 第 4 作者
（37） New photostable naphthalimide-based fluorescent probe for mitochondrial imaging and tracking, BIOSENSORS AND BIOELECTRONICS, 2015, 第 4 作者
（38） The unexpected effect of PEGylated gold nanoparticles on the primary function of erythrocytes, NANOSCALE, 2014, 第 3 作者
（39） The protective effects of Trolox-loaded chitosan nanoparticles against hypoxia-mediated cell apoptosis, NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2014, 第 1 作者  通讯作者
（40） A potential tool for future antioxidant therapy, FREE RADICAL RESEARCH, 2014, 第 1 作者
（41） Synthesis of a Fluorescence Labeled Spin Trap and Its ESR Study, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2014, 第 2 作者
（42） Targeted surface-functionalized gold nanoclusters for mitochondrial imaging, BIOSENSORS & BIOELECTRONICS, 2014, 第 3 作者
（43） 荧光自旋捕获探针的合成及ESR捕获研究, Synthesis of a Fluorescence Labeled Spin Trap and Its ESR Study���, 高等学校化学学报, 2014, 第 2 作者
（44） Arsenite binding-induced zinc loss from PARP-1 is equivalent to zinc deficiency in reducing PARP-1 activity, leading to inhibition of DNA repair, TOXICOLOGY AND APPLIED PHARMACOLOGY, 2014, 第 3 作者
（45） Highly sensitive free radical detection by nitrone-functionalized gold nanoparticles, NANOSCALE, 2014, 第 1 作者
（46） Effects of nanoparticle size and gestational age on maternal biodistribution and toxicity of gold nanoparticles in pregnant mice, TOXICOLOGY LETTERS, 2014, 第 2 作者
（47） 树枝状大分子（PAMAM）的合成与表征及端基分析, Synthesis, Characterization and End-group Analysis of PAMAM Dedeimers, 贵州师范大学学报：自然科学版, 2013, 第 2 作者
（48） Mechanism and Cellular Kinetic Studies of the Enhancement of Antioxidant Activity by Using Surface-Functionalized Gold Nanoparticles, CHEMISTRY-A EUROPEAN JOURNAL, 2013, 第 1 作者
（49） An effective strategy for the synthesis of biocompatible gold nanoparticles using danshensu antioxidant: prevention of cytotoxicity via attenuation of free radical formation, NANOTOXICOLOGY, 2013, 第 1 作者
（50） An effective strategy for the synthesis of biocompatible gold nanoparticles using danshensu antioxidant: prevention of cytotoxicity via attenuation of free radical formation., NANOTOXICOLOY, 2013, 第 1 作者
（51） Hydroxyethylated graphene oxide as potential carriers for methotrexate delivery, JOURNAL OF NANOPARTICLE RESEARCH, 2013, 第 1 作者  通讯作者
（52） Mechanism and Cellular Kinetics Studies of Enhancement of Antioxidant Activity through Surface Functionalized Gold Nanoparticles., CHEMISTRY A EUROPEAN JOURNAL, 2013, 第 1 作者
（53） Polyamidoamine dendrimer conjugated chitosan nanoparticles for the delivery of methotrexate, CARBOHYDRATE POLYMERS, 2013, 第 10 作者
（54） Intrauterine inflammation increase materno-fetal transfer of gold nanoparticles in a size-dependent manner in Murine pregnancy., SMALL, 2013, 第 3 作者
（55） Intrauterine Inflammation Increases Materno-Fetal Transfer of Gold Nanoparticles in a Size-Dependent Manner in Murine Pregnancy, SMALL, 2013, 
（56） Hydroxyethyl-functionalized ultrasmall chitosan nanoparticles as a gene delivery carrier, RSC ADVANCES, 2013, 第 1 作者
（57） Hydroxy-terminated poly(amidoamine) dendrimers as nanocarriers for the delivery of antioxidants, JOURNAL OF NANO RESEARCH, 2013, 第 8 作者
（58） Detection of nitric oxide in macrophage cells for the assessment of the cytotoxicity of gold nanoparticles, TALANTA, 2012, 第 1 作者
（59） Inhibitory effects of trolox-encapsulated chitosan nanoparticles on tert-butylhydroperoxide induced RAW264.7 apoptosis, BIOMATERIALS, 2012, 第 2 作者  通讯作者
（60） Protecting effect of phosphorylation on oxidative damage of D1 protein by down-regulating the production of superoxide anion in photosystem II membranes under high light, PHOTOSYNTHESIS RESEARCH, 2012, 第 4 作者
（61） 电子自旋共振－自由基捕获技术在生物学中的应用, Applications of Electron Spin Resonance in Biology, 生物物理学报, 2012, 第 1 作者
（62） 自组装Trolox-壳聚糖纳米颗粒对CoC12诱导的氧化应激损伤中PC12细胞的保护效果研究, Research on the Protective Effect of Trolox-Chitosan Nanoparticles Against Oxidative Stress Injury of PC12 Induced by COCI2, 生物物理学报, 2012, 第 2 作者
（63） Effect of Phosphorylation on the Production of 7900 and 9300 Fragments of D1 Protein, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2012, 第 2 作者
（64） Effects of gestational age and surface modification on materno-fetal transfer of nanoparticles in murine pregnancy, SCIENTIFIC REPORTS, 2012, 第 6 作者
（65） Novel glutathione-linked nitrones as dual free radical probes, NEW JOURNAL OF CHEMISTRY, 2011, 第 3 作者
（66） 新型Trolox-壳聚糖纳米颗粒的制备及抗氧化效应, Preparation of Novel Trolox-chitosan Nanoparticles and Its Anti-oxidation Activity, 高等学校化学学报, 2011, 第 2 作者
（67） Gold nanoparticles-based catalysis for detection of S-nitrosothiols in blood serum, TALANTA, 2011, 第 6 作者
（68） Release of the Oxygen-Evolving Complex Subunits from Photosystem II Membranes in Phosphorylation Condition under Light Stress, Release of the Oxygen-Evolving Complex Subunits from Photosystem II Membranes in Phosphorylation Condition under Light Stress, 中国化学：英文版, 2011, 第 3 作者
（69） Release of the Oxygen-Evolving Complex Subunits from Photosystem II Membranes in Phosphorylation Condition under Light Stress~?, CHINESE JOURNAL OF CHEMISTRY, 2011, 第 3 作者
（70） Preparation of Novel Trolox-chitosan Nanoparticles and Its Anti-oxidation Activity, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2011, 第 2 作者
（71） Nitric oxide metabolism controlled by formaldehyde dehydrogenase (fdh, homolog of mammalian GSNOR) plays a crucial role in visual pattern memory in Drosophila, NITRIC OXIDE-BIOLOGY AND CHEMISTRY, 2011, 第 11 作者
（72） Effect of 2,5-substituents on the stabilituy of cyclic nitrone superoxide spin adducts:A density functional theory approach, FREE RADICAL RESEARCH, 2010, 第 1 作者
（73） 内源性超氧阴离子自由基介导的莱茵衣藻光系统Ⅱ蛋白组分损伤, Damages to PS��� Component Proteins by Endogenous Superoxide Anion Radicals in Chlamydomonas reinhardtii, 生物物理学报, 2010, 第 2 作者
（74） Protecting Effects of the Selfassembling Troloxchitosan Nanoparticles Against t-BHP-induced Cell Apoptosis, FREE RADICAL BIOLOGY AND MEDICINE, 2010, 第 3 作者
（75） 中国自由基捕获技术发展30年, Spin Trapping in China: An Overview of the Past 30 Years, 波谱学杂志, 2010, 第 2 作者
（76） 链接琥珀酰亚胺的线性硝酮的合成与ESR研究, Succinimide-Linked Nitrone. Synthesis and ESR Studies, 波谱学杂志, 2010, 第 1 作者
（77） Gold Nanoparticles-mediated Releasing of Nitric Oxide from RSNOs, FREE RADICAL BIOLOGY AND MEDICINE, 2010, 第 5 作者
（78） Effect of 2, 5-Substituents on the Stability of Cyclic Nitrone Superoxide Spin Adducts: A Density Functional Theory Approach, FREE RADICAL RESEARCH, 2010, 第 1 作者
（79） 一项可能改变烟草历史的研究成果, 中国科学：生命科学, 2010, 第 2 作者
（80） Autoxidtion and Prooxidation Mechanisms of Danshensu, 物理化学学报, 2010, 第 2 作者
（81） 丹参素自氧化与促氧化机理, Autoxidation and Prooxidation Mechanisms of Danshensu, 物理化学学报, 2010, 第 3 作者
（82） Autoxidation and Prooxidation Mechanisms of Danshensu, ACTA PHYSICO-CHIMICA SINICA, 2010, 第 3 作者
（83） 新型饱和烷基类自由基捕捉剂的合成及ESR研究, Syntheses and Spin Trapping-ESR Studies of Novel Saturated Alkyl Spin-traps, 波谱学杂志, 2009, 第 3 作者
（84） Synthesis and ESR Study of Covalent Connection of EMPO on L-Tyr, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 第 1 作者
（85） EMPO-酪氨酸共价链接物的合成与ESR研究, Synthesis and ESR Study of Covalent Connection of EMPO on L-Tyr, 高等学校化学学报, 2009, 第 2 作者
（86） Studies on Intermolecular Synergistic Antioxidant Activity in Glyceride Tri-ferulate, CHEMICAL JOURNAL OF CHINESE UNIVERSITIES-CHINESE, 2009, 第 2 作者
（87） Potential Oxidative Stress of Gold Nanoparticles by Induced-NO Releasing in Serum, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2009, 第 5 作者
（88） 阿魏酸丙三酯的分子内协同抗氧化作用研究, Studies on Intermolecular Synergistic Antioxidant Activity in Glyceride Tri-ferulate, 高等学校化学学报, 2009, 第 2 作者
（89） Influence of preparation methods on the structures and properties for the blends between polyamide 6co6T and polyamide 6: Melt-mixing and in-situ blending, JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 2008, 第 3 作者
（90） 单细胞光合生物莱茵衣藻光系统Ⅱ产生超氧阴离子自由基的ESR研究, Spin Trapping-ESR Studies on The Superoxide Anion Radical Generated in Photosystem��� of Unicellular Green Alga Chlamydomonas reinhardtii, 生物化学与生物物理进展, 2008, 第 3 作者
（91） Spin trapping-ESR studies on the superoxide anion radical generated in photosystem II of unicellular green alga Chlamydomonas reinhardtii, PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2008, 第 3 作者