基本信息
刘肇祺  男  硕导  中国科学院北京基因组研究所(国家生物信息中心)
电子邮件: liuzq@big.ac.cn
通信地址: 北京市朝阳区北辰西路1号院104号楼
邮政编码:

招生信息

   
招生专业
0710J3-生物信息学
0710Z1-基因组学
招生方向
癌症基因组学

教育背景

2010-09--2015-07   中国科学院数学与系统科学研究院   博士
2006-09--2010-07   中国农业大学   学士

工作经历

   
工作简历
2020-10~现在, 中国科学院北京基因组研究所(国家生物信息中心), 研究员
2018-09~2020-08,Columbia University, Associate Research Scientist
2015-09~2018-08,Columbia University, Postdoctoral Researcher
2010-09~2015-07,中国科学院数学与系统科学研究院, 博士
2006-09~2010-07,中国农业大学, 学士

出版信息

   
发表论文
(1) SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 第 2 作者
(2) SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2022, 第 2 作者
(3) Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy, Nature genetics, 2021, 第 2 作者
(4) Mutant SF3B1 promotes AKT- and NF-kappa B driven mammary tumorigenesis, JOURNAL OF CLINICAL INVESTIGATION, 2021, 第 2 作者
(5) Computing the Role of Alternative Splicing in Cancer, Trends in cancer, 2021, 通讯作者
(6) The UVSSA complex alleviates MYC-driven stress, JOURNAL OF CELL BIOLOGY, 2021, 第 3 作者
(7) The UVSSA complex alleviates MYC-driven transcription stress, Journal of Cell Biology, 2021, 第 1 作者
(8) Mutant SF3B1 promotes AKT and NF-kB driven mammary tumorigenesis, The Journal of Clinical Investigation, 2021, 第 1 作者
(9) Pharmacogenomic landscape of patient-derived tumor cells informs precision oncology therapy, Nature genetics, 2021, 第 2 作者
(10) Mutant SF3B1 promotes AKT- and NF-kappa B driven mammary tumorigenesis, JOURNAL OF CLINICAL INVESTIGATION, 2021, 第 2 作者
(11) Computing the Role of Alternative Splicing in Cancer, Trends in cancer, 2021, 通讯作者
(12) The UVSSA complex alleviates MYC-driven stress, JOURNAL OF CELL BIOLOGY, 2021, 第 3 作者
(13) The UVSSA complex alleviates MYC-driven transcription stress, Journal of Cell Biology, 2021, 第 1 作者
(14) Mutant SF3B1 promotes AKT and NF-kB driven mammary tumorigenesis, The Journal of Clinical Investigation, 2021, 第 1 作者
(15) Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization, CANCER DISCOVERY, 2020, 第 1 作者
(16) Genomic Characterization of HIV-Associated Plasmablastic Lymphoma Identifies Pervasive Mutations in the JAK–STAT Pathway, Blood Cancer Discovery, 2020, 第 1 作者
(17) Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 第 1 作者
(18) A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries, CANCERS, 2020, 第 5 作者
(19) Mutations in the RNA Splicing Factor SF3B1 Promote Tumorigenesis through MYC Stabilization, CANCER DISCOVERY, 2020, 第 1 作者
(20) Genomic Characterization of HIV-Associated Plasmablastic Lymphoma Identifies Pervasive Mutations in the JAK–STAT Pathway, Blood Cancer Discovery, 2020, 第 1 作者
(21) Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 第 1 作者
(22) A Novel JAK1 Mutant Breast Implant-Associated Anaplastic Large Cell Lymphoma Patient-Derived Xenograft Fostering Pre-Clinical Discoveries, CANCERS, 2020, 第 5 作者
(23) Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1, MOLECULAR CELL, 2019, 第 4 作者
(24) Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma, GUT, 2019, 第 2 作者
(25) Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target, EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, 第 4 作者
(26) Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1, MOLECULAR CELL, 2019, 第 4 作者
(27) Comprehensive characterisation of compartment-specific long non-coding RNAs associated with pancreatic ductal adenocarcinoma, GUT, 2019, 第 2 作者
(28) Secretome analysis of patient-derived GBM tumor spheres identifies midkine as a potent therapeutic target, EXPERIMENTAL AND MOLECULAR MEDICINE, 2019, 第 4 作者
(29) Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 其他(合作组作者)
(30) Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2018, 其他(合作组作者)
(31) Clonal Evolution of Glioblastoma under Therapy, NATURE GENETICS, 2016, 第 8 作者
(32) Clonal Evolution of Glioblastoma under Therapy, NATURE GENETICS, 2016, 第 8 作者

科研活动

   
科研项目
( 1 ) 泛癌基因组可变剪切调控关系的深度挖掘, 负责人, 国家任务, 2022-01--2025-12