基本信息
高宏  男  硕导  中国科学院水生生物研究所
电子邮件: gaoh@ihb.ac.cn
通信地址: 中国科学院水生生物研究所
邮政编码: 430072

招生信息

   
招生专业
071007-遗传学
071005-微生物学
招生方向
藻类分子遗传学
微生物生理生化

教育背景

2001-09--2007-05   中国科学院水生生物研究所   理学博士
1993-09--1996-10   武汉大学生科院   理学硕士
1989-09--1993-07   武汉大学生科院   理学学士

工作经历

   
工作简历
2001-09~2007-05,中国科学院水生生物研究所, 理学博士
1996-07~2013-05,中国科学院水生生物研究所, 研究实习员、助理研究员、副研究员
1993-09~1996-10,武汉大学生科院, 理学硕士
1989-09~1993-07,武汉大学生科院, 理学学士

专利与奖励

   
专利成果
( 1 ) 一种链带藻NMX451的获得和遗传转化的方法, 2016, 第 4 作者, 专利号: ZL 2013 1 0407874.4

( 2 ) 产油单针藻LB50的获得及应用, 2015, 第 4 作者, 专利号: ZL 2013 1 0426399.5

( 3 ) 产油单针藻LB59的获得及应用, 2015, 第 4 作者, 专利号: ZL 2013 1 0428561.7

( 4 ) 一种识别对虾白斑杆状病毒的单链抗体A1极其用途, 2004, 第 1 作者, 专利号: ZL 00131231.6

( 5 ) 对虾白斑杆状病毒的诊断试剂盒及其检测方法, 2003, 第 2 作者, 专利号: ZL 00131230.8

出版信息

   
发表论文
(1) 多变鱼腥藻ATCC 29413基因的一步插入失活, ONE-STEP GENE INTERRUPTION IN ANABAENA VARIABILIS ATCC 29413, 水生生物学报, 2021, 第 4 作者
(2) 多变鱼腥藻ATCC 29413基因的一步插入失活, ONE-STEP GENE INTERRUPTION IN ANABAENA VARIABILIS ATCC 29413, 水生生物学报, 2021, 第 4 作者
(3) Early Stage Adaptation of a Mesophilic Green Alga to Antarctica: Systematic Increases in Abundance of Enzymes and LEA Proteins, MOLECULAR BIOLOGY AND EVOLUTION, 2020, 第 3 作者
(4) Early Stage Adaptation of a Mesophilic Green Alga to Antarctica: Systematic Increases in Abundance of Enzymes and LEA Proteins, MOLECULAR BIOLOGY AND EVOLUTION, 2020, 第 3 作者
(5) 集胞藻PCC 6803高产精氨酸藻株的紫外诱变选育, CREATION OF HIGH ARGININE PRODUCING STRAIN OF SYNECHOCYSTIS SP.PCC 6803 BY UV MUTAGENESIS, 水生生物学报, 2018, 第 2 作者
(6) 一株富含a-亚麻酸栅藻的异样培养条件优化, 水生生物学报, 2018, 第 1 作者
(7) Three substrains of the cyanobacterium anabaena sp. strain PCC 7120 display divergence in genomic sequence and hetC fuction, Journal of Bacteriology, 2018, 第 1 作者
(8) 集胞藻PCC 6803高产精氨酸藻株的紫外诱变选育, CREATION OF HIGH ARGININE PRODUCING STRAIN OF SYNECHOCYSTIS SP.PCC 6803 BY UV MUTAGENESIS, 水生生物学报, 2018, 第 2 作者
(9) 一株富含a-亚麻酸栅藻的异样培养条件优化, 水生生物学报, 2018, 第 1 作者
(10) Three substrains of the cyanobacterium anabaena sp. strain PCC 7120 display divergence in genomic sequence and hetC fuction, Journal of Bacteriology, 2018, 第 1 作者
(11) 应用生物膜干涉技术检测鱼腥藻HetR结合靶DNA的亲和力, DETECTION OF THE AFFINITY OF HETR, THE KEY REGULATOR OFHETEROCYST DIFFERENTIATION, WITH ITS TARGET DNA INANABAENA BY BIOLAYER INTERFEROMETRY, 水生生物学报, 2017, 第 3 作者
(12) Arsenic Methyltransferase is Involved in Arsenosugar Biosynthesis by Providing DMA, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 第 6 作者
(13) 应用生物膜干涉技术检测鱼腥藻HetR结合靶DNA的亲和力, DETECTION OF THE AFFINITY OF HETR, THE KEY REGULATOR OFHETEROCYST DIFFERENTIATION, WITH ITS TARGET DNA INANABAENA BY BIOLAYER INTERFEROMETRY, 水生生物学报, 2017, 第 3 作者
(14) Arsenic Methyltransferase is Involved in Arsenosugar Biosynthesis by Providing DMA, ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2017, 第 6 作者
(15) 一株耐NaHCO3高含油绿藻的筛选鉴定, SELECTION AND IDENTIFICATION OF A NaHCO3-TOLERANT HIGH-OIL-CONTENT GREEN ALGAE, 水生生物学报, 2016, 第 4 作者
(16) pH-dependent gas vesicle formation in Microcystis, FEBS LETTERS, 2016, 第 1 作者
(17) 一株耐NaHCO3高含油绿藻的筛选鉴定, SELECTION AND IDENTIFICATION OF A NaHCO3-TOLERANT HIGH-OIL-CONTENT GREEN ALGAE, 水生生物学报, 2016, 第 4 作者
(18) pH-dependent gas vesicle formation in Microcystis, FEBS LETTERS, 2016, 第 1 作者
(19) 适于沙漠地下水培养的耐碳酸氢钠产油微藻, Na2HCO3-TOLERANT OIL-PRODUCING MICROALGAE THAT ARE SUITABLE FOR CULTIVATION WITH DESERT GROUNDWATER, 水生生物学报, 2015, 第 2 作者
(20) The HetR-binding site that activates expression of patA in vegetative cells is required for normal heterocyst patterning in Anabaena sp. PCC 7120, SCIENCE BULLETIN, 2015, 第 4 作者
(21) 适于沙漠地下水培养的耐碳酸氢钠产油微藻, Na2HCO3-TOLERANT OIL-PRODUCING MICROALGAE THAT ARE SUITABLE FOR CULTIVATION WITH DESERT GROUNDWATER, 水生生物学报, 2015, 第 2 作者
(22) The HetR-binding site that activates expression of patA in vegetative cells is required for normal heterocyst patterning in Anabaena sp. PCC 7120, SCIENCE BULLETIN, 2015, 第 4 作者
(23) 蓝细菌病毒A-4L 在鱼腥藻(Anabaena variabilis)藻苔中形成同心圆噬斑的成因, Main reason for concentric rings plaque formation of virus infecting cyanobacteria (A-4L) in lawns of Anabaena variabilis, 微生物学报, 2014, 第 3 作者
(24) 蓝细菌病毒A-4L 在鱼腥藻(Anabaena variabilis)藻苔中形成同心圆噬斑的成因, Main reason for concentric rings plaque formation of virus infecting cyanobacteria (A-4L) in lawns of Anabaena variabilis, 微生物学报, 2014, 第 3 作者
(25) Role of two phosphohexomutase genes in glycogen synthesis in Synechocystis sp. PCC6803, Chinese Science Bulletin, 2013, 
(26) Role of two phosphohexomutase genes in glycogen synthesis in Synechocystis sp. PCC6803, Chinese Science Bulletin, 2013, 
(27) The cyanobacterial NAD kinase gene sll1415 is required for photoheterotrophic growth and cellular redox homeostasis in Synechocystis sp. PCC 6803, Journal of Bacteriology, 2012, 
(28) Identification of a novel thylakoid protein gene involved in cold acclimation in cyanobacteria, MICROBIOLOGY-SGM, 2012, 第 2 作者
(29) The cyanobacterial NAD kinase gene sll1415 is required for photoheterotrophic growth and cellular redox homeostasis in Synechocystis sp. PCC 6803, Journal of Bacteriology, 2012, 
(30) Identification of a novel thylakoid protein gene involved in cold acclimation in cyanobacteria, MICROBIOLOGY-SGM, 2012, 第 2 作者
(31) Identification and characterization of genes encoding two novel LEA proteins in Antarctic and temperate strains of Chlorella vulgaris, GENE, 2011, 第 3 作者
(32) Microalgae as platforms for production of recombinant proteins and valuable compounds: progress and prospects (Review), JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2011, 第 5 作者
(33) Role of Rbp1 in the Acquired Chill-Light Tolerance of Cyanobacteria ▿ †, JOURNAL OF BACTERIOLOGY, 2011, 第 5 作者
(34) Characterization of the tandem-arrayed hiC6 genes in Antarctic and temperate strains of Chlorella vulgaris, FEMS MICROBIOLOGY LETTERS, 2011, 第 3 作者
(35) Microalgae as platforms for production of recombinant proteins and valuable compounds: progress and prospects (Review), JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 2011, 第 5 作者
(36) Identification and characterization of genes encoding two novel LEA proteins in Antarctic and temperate strains of Chlorella vulgaris, GENE, 2011, 第 3 作者
(37) Role of Rbp1 in the Acquired Chill-Light Tolerance of Cyanobacteria ▿ †, JOURNAL OF BACTERIOLOGY, 2011, 第 5 作者
(38) Characterization of the tandem-arrayed hiC6 genes in Antarctic and temperate strains of Chlorella vulgaris, FEMS MICROBIOLOGY LETTERS, 2011, 第 3 作者
(39) Expression of organophosphorus-degradation gene (opd) in aggregating and non-aggregating filamentous nitrogen-fixing cyanobacteria, CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2010, 通讯作者
(40) Expression of organophosphorus-degradation gene (opd) in aggregating and non-aggregating filamentous nitrogen-fixing cyanobacteria, CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY, 2010, 通讯作者
(41) Depletion of Vipp1 in Synechocystis sp PCC 6803 affects photosynthetic activity before the loss of thylakoid membranes, FEMS MICROBIOLOGY LETTERS, 2009, 第 1 作者
(42) Depletion of Vipp1 in Synechocystis sp PCC 6803 affects photosynthetic activity before the loss of thylakoid membranes, FEMS MICROBIOLOGY LETTERS, 2009, 第 1 作者
(43) 集胞藻PCC6803铜离子诱导表达平台的构建, 水生生物学报, 2007, 第 1 作者
(44) The high variability of gvpA-gvpC regions in Microcystis, Progress in Natural Science, 2007, 第 1 作者
(45) A gene cluster that regulates both heterocyst differentiation and pattern formation in Anabaena sp strain PCC 7120, MOLECULAR MICROBIOLOGY, 2007, 第 5 作者
(46) 集胞藻PCC6803铜离子诱导表达平台的构建, 水生生物学报, 2007, 第 1 作者
(47) The high variability of gvpA-gvpC regions in Microcystis, Progress in Natural Science, 2007, 第 1 作者
(48) A gene cluster that regulates both heterocyst differentiation and pattern formation in Anabaena sp strain PCC 7120, MOLECULAR MICROBIOLOGY, 2007, 第 5 作者

科研活动

   
科研项目
( 1 ) 适应沙漠地区的产油藻种选育, 负责人, 国家任务, 2011-01--2013-12
( 2 ) 宁夏等地产油微藻调查, 负责人, 国家任务, 2012-05--2017-04
( 3 ) 适用于CO2减排微藻藻种的选育, 负责人, 国家任务, 2012-05--2017-05
( 4 ) 利用微藻消除石化企业NOx尾气生产高值产品的技术研发与示范, 参与, 中国科学院计划, 2016-01--2017-12
( 5 ) 耐NaHCO3产油微藻的筛选、鉴定, 负责人, 研究所自选, 2015-01--2015-12
( 6 ) 集胞蓝细菌RNA结合蛋白Rbp3的转录后调控功能, 参与, 国家任务, 2015-01--2018-12
( 7 ) hetZ基因调控丝状固氮蓝细菌细胞分化的机理, 参与, 国家任务, 2013-01--2016-12
( 8 ) 氮和温度对湖泊水华藻类群落的多尺度调控机理, 参与, 研究所自选, 2016-01--2020-12
( 9 ) 中线总干渠藻类、贝类异常增殖成因及防控技术研究, 负责人, 国家任务, 2017-04--2020-04
( 10 ) 人工噬藻体的设计、合成与拯救, 参与, 国家任务, 2019-07--2024-06
( 11 ) 发酵法制备岩藻糖基乳糖及唾液酸乳糖, 负责人, 企业委托, 2020-07--2022-07