0707Z1-海洋生态学
086000-生物与医药

生物资源生态学，养殖生态学，海洋生物工程
海洋生物工程

2008-09--2013-06   中国科学院海洋研究所   博士学位
2004-09--2008-06   中国海洋大学   学士学位

   

2022-09~现在, 中国科学院海洋研究所, 研究员
2017-01~2022-09,中国科学院海洋研究所, 副研究员
2013-07~2016-12,中国科学院海洋研究所, 助理研究员

2021-11-27-今,中国新农科水产联盟专家委员会, 委员
2020-01-01-今,山东省青年联合会, 委员

   

（1） 刺参对环境胁迫的特殊行为响应及其调控机制, 二等奖, 省级, 2021
（2） 中国科学院沈阳分院优秀青年科技人才奖, 一等奖, 院级, 2020
（3） 刺参高效配合饲料关键技术与产业化应用, 二等奖, 省级, 2019
（4） 现代海洋牧场构建技术创新与集成应用团队, 一等奖, 部委级, 2017
（5） 刺参良种生态高效增养殖设施和关键技术创新与应用, 二等奖, 部委级, 2014

[1] 一种仿刺参性别鉴定的分子标记及应用. 2024-01-02.
[2] 孙丽娜, 吴千文, 崔玮, 霍达, 张立斌, 江春嬉. 一种海参智能倒池与生长监测、预测一体化装置和方法. CN119737864A, 2025-04-01.
[3] 林承刚, 孙景春, 孙丽娜, 高焕鑫, 刘石林, 张立斌, 杨红生. 一种利用海参、鲍处理工厂化养殖尾水的设施及方法. CN: CN118993359B, 2024-12-20.
[4] 孙丽娜, 崔玮, 刘石林, 苏芳, 杨红生, 许帅, 张立斌, 江春嬉. 基于全基因组关联分析的仿刺参生长性状SNP分子标记组合与应用. CN: CN118562976B, 2024-11-08.
[5] 孙丽娜, 江春嬉, 赵宏远, 刘石林, 崔玮, 许帅, 苏芳, 杨红生. 一种仿刺参性别鉴定的分子标记及应用. CN: CN117004701B, 2024-01-02.
[6] 孙丽娜, 江春嬉, 赵宏远, 刘石林, 崔玮, 许帅, 苏芳, 杨红生. 一种仿刺参性别鉴定的分子标记及应用. CN: CN117004701A, 2023-11-07.
[7] 孙丽娜, 崔玮, 刘石林, 杨红生, 邢丽丽, 林承刚. 一种与刺参生长性状相关的基因分子标记及其应用. CN: CN116497129A, 2023-07-28.
[8] 张立斌, 许帅, 刘石林, 霍达, 林承刚, 孙景春, 孙丽娜, 杨红生. 刺参精子低温保存液及应用和刺参精子的保存方法. CN: CN116034992A, 2023-05-02.
[9] 孙丽娜, 崔玮, 刘石林, 蒋友如, 曹明月, 杨红生, 许帅, 林承刚. 一种仿刺参全基因组30K液相育种芯片及其应用. CN: CN116497124A, 2023-07-28.
[10] 童浩宇, 林承刚, 张立斌, 刘石林, 孙景春, 孙丽娜, 杨红生. 一种实验用海洋生物幼虫感光反应检测装置及方法. CN: CN116762735A, 2023-09-19.
[11] 霍达, 孙丽娜, 林承刚, 杨红生, 张立斌, 刘石林, 崔玮, 苏芳. 一种刺参体液样品外泌体分离的方法. CN: CN114700186A, 2022-07-05.
[12] 邢丽丽, 刘石林, 江春嬉, 杨红生, 孙丽娜, 张立斌. 一种刺参基因编辑体系的构建方法. CN: CN114214364A, 2022-03-22.
[13] 刘石林, 林承刚, 孙景春, 孙丽娜, 邢丽丽, 茹小尚, 张立斌, 杨红生. 一种多刺速生刺参品系的选育方法. CN: CN113424785A, 2021-09-24.
[14] 刘石林, 孙景春, 林承刚, 张永安, 孙丽娜, 邢丽丽, 茹小尚, 许帅, 张立斌, 杨红生. 一种刺参养殖池塘底质改良设施. CN: CN214126584U, 2021-09-07.
[15] 刘石林, 孙景春, 林承刚, 张永安, 孙丽娜, 邢丽丽, 茹小尚, 许帅, 张立斌, 杨红生. 一种刺参养殖池塘底质改良设施及其使用方法. CN: CN112425556A, 2021-03-02.
[16] 林承刚, 孙景春, 孙丽娜, 刘石林, 张立斌, 杨红生, 王旭, 范鑫昊, 高焕鑫. 一种快速批量测定海胆壳径的装备. CN: CN213335988U, 2021-06-01.
[17] 林承刚, 孙景春, 孙丽娜, 刘石林, 张立斌, 杨红生, 王旭, 范鑫昊, 高焕鑫. 一种快速批量测定海胆壳径的装备及其测定方法. CN: CN112240750A, 2021-01-19.
[18] 张立斌, 许帅, 刘石林, 林承刚, 孙景春, 孙丽娜, 杨红生. 一种冷冻保护液及刺参精子超低温冷冻保存方法. CN: CN112075415B, 2021-08-31.
[19] 林承刚, 范鑫昊, 张立斌, 杨红生, 孙景春, 丁奎, 茹小尚, 孙丽娜, 刘石林, 周文礼. 一种浅海海参诱捕器. CN: CN112042608A, 2020-12-08.
[20] 杨红生, 宋肖跃, 林承刚, 周毅, 王先锋, 刘清远, 张涛, 张立斌, 孙丽娜, 刘石林, 孙景春. 适用于海洋牧场底栖环境调查的沉积物采集与分切装置. CN: CN106840776A, 2017-06-13.
[21] 杨红生, 宋肖跃, 林承刚, 周毅, 王先锋, 王金霞, 张涛, 张立斌, 孙丽娜, 刘石林, 孙景春. 一种磁力约束单向流阀负压式潮间带浅水沉积物采集器. CN: CN106950075A, 2017-07-14.
[22] 林承刚, 杨红生, 张立斌, 张涛, 周毅, 许强, 刘石林, 孙丽娜, 孙景春. 一种海洋底栖生物附着力测定装置. CN: CN104542395A, 2015-04-29.
[23] 杨红生, 林承刚, 张立斌, 邱天龙, 张涛, 阚仁涛, 周毅, 许强, 刘石林, 孙丽娜. 一种实验用可调节流速的模拟水流装置. CN: CN103404456A, 2013-11-27.

   

[1] Su, Fang, Dolmatov, Igor Yu, Cui, Wei, Yang, Hongsheng, Sun, Lina. Molecular dynamics and spatial response of proliferation and apoptosis in wound healing and early intestinal regeneration of sea cucumber Apostichopus japonicus. DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY[J]. 2025, 第 5 作者  通讯作者  162: http://dx.doi.org/10.1016/j.dci.2024.105297.
[2] Su, Fang, Huo, Da, Yang, Hongsheng, Sun, Lina. CircRNA8388 functions as the sponge for miR-2392 during intestinal regeneration in sea cucumber Apostichopus japonicus. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES[J]. 2024, 第 4 作者  通讯作者  274(null): http://dx.doi.org/10.1016/j.ijbiomac.2024.133302.
[3] Jiang, Chunxi, Sun, Lina, Yang, Hongsheng. Promoter methylation as a potential cause for the decrease in pyruvate metabolism during environmentally induced aestivation in Apostichopus japonicus. AQUACULTURE[J]. 2024, 第 2 作者579: http://dx.doi.org/10.1016/j.aquaculture.2023.740135.
[4] Chunxi Jiang, Hongsheng Yang, Bohong Liu, Lina Sun. Genome variations in sea cucumbers: Insights from genome survey sequencing and comparative analysis of mitochondrial genomes. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics[J]. 2024, 第 4 作者null(null): 
[5] Molecular Ecology. 2024,   通讯作者  
[6] Huo, Da, Zhang, Libin, Yang, Hongsheng, Sun, Lina. Adaptation to hypoxic stress involves amino acid metabolism: A case in sea cucumber. ENVIRONMENTAL POLLUTION[J]. 2023, 第 4 作者  通讯作者  330: http://dx.doi.org/10.1016/j.envpol.2023.121766.
[7] Huo, Da, Su, Fang, Yang, Hongsheng, Sun, Lina. Exosomal microRNAs regulate the heat stress response in sea cucumber Apostichopus japonicus. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2023, 第 4 作者  通讯作者  249: http://dx.doi.org/10.1016/j.ecoenv.2022.114419.
[8] Xing, Lili, Liu, Shilin, Zhang, Libin, Yang, Hongsheng, Sun, Lina. MITF Contributes to the Body Color Differentiation of Sea Cucumbers Apostichopus japonicus through Expression Differences and Regulation of Downstream Genes. BIOLOGY-BASEL[J]. 2023, 第 5 作者  通讯作者  12(1): 
[9] Su, Fang, Liu, Shilin, Xing, Lili, Huo, Da, Yang, Hongsheng, Sun, Lina. Understanding gene regulation during the development of the sea cucumber Apostichopus japonicus using comparative transcriptomics. FRONTIERS IN MARINE SCIENCE[J]. 2023, 第 6 作者  通讯作者  10: http://dx.doi.org/10.3389/fmars.2023.1087339.
[10] Sun, Lina, Jiang, Chunxi, Su, Fang, Cui, Wei, Yang, Hongsheng. Chromosome-level genome assembly of the sea cucumber Apostichopus japonicus. SCIENTIFIC DATA[J]. 2023, 第 1 作者  通讯作者  10(1): http://dx.doi.org/10.1038/s41597-023-02368-9.
[11] International Journal of Molecular Sciences. 2023,   通讯作者  
[12] Scientific data. 2023, 第 1 作者
[13] Huo, Da, Su, Fang, Cui, Wei, Liu, Shilin, Zhang, Libin, Yang, Hongsheng, Sun, Lina. Heat stress and evisceration caused lipid metabolism and neural transduction changes in sea cucumber: Evidence from metabolomics. MARINE POLLUTION BULLETIN[J]. 2022, 第 7 作者  通讯作者  182: http://dx.doi.org/10.1016/j.marpolbul.2022.113993.
[14] Xing, Lili, Liu, Shilin, Zhang, Libin, Yang, Hongsheng, Sun, Lina. Landscape and dynamics of accessible chromatin during pigmentation process in green, white and purple sea cucumber Apostichopus japonicus. AQUACULTURE REPORTS[J]. 2022, 第 5 作者  通讯作者  23: https://doaj.org/article/23af458bb9624ff2a30bc8b257673a5a.
[15] Cui, Wei, Huo, Da, Liu, Shilin, Xing, Lili, Su, Fang, Yang, Hongsheng, Sun, Lina. Construction of a High-Density Genetic Linkage Map for the Mapping of QTL Associated with Growth-Related Traits in Sea Cucumber (Apostichopus japonicus). BIOLOGY-BASEL[J]. 2022, 第 7 作者  通讯作者  11(1): 
[16] Xu, Shuai, Liu, Shilin, Sun, Jingchun, Zhang, Libin, Lin, Chenggang, Sun, Lina, Xing, Lili, Jiang, Chunxi, Yang, Hongsheng. Optimizing cryopreservation of sea cucumber (Apostichopus japonicus) sperm using a programmable freezer and computer-assisted sperm analysis (vol 9, 917045, 2022). FRONTIERS IN MARINE SCIENCE. 2022, 第 6 作者9: 
[17] Su, Fang, Yang, Hongsheng, Sun, Lina. A Review of Histocytological Events and Molecular Mechanisms Involved in Intestine Regeneration in Holothurians. BIOLOGY-BASEL. 2022, 第 3 作者  通讯作者  11(8): http://dx.doi.org/10.3390/biology11081095.
[18] Xu, Shuai, Liu, Shilin, Sun, Jingchun, Zhang, Libin, Lin, Chenggang, Sun, Lina, Xing, Lili, Jiang, Chunxi, Yang, Hongsheng. Optimizing cryopreservation of sea cucumber (Apostichopus japonicus) sperm using a programmable freezer and computer-assisted sperm analysis. FRONTIERS IN MARINE SCIENCE[J]. 2022, 第 6 作者9: http://dx.doi.org/10.3389/fmars.2022.917045.
[19] Xing, Lili, Sun, Lina, Liu, Shilin, Zhang, Libin, Sun, Jingchun, Yang, Hongsheng. Metabolomic analysis of white, green and purple morphs of sea cucumber Apostichopus japonicus during body color pigmentation process. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS[J]. 2021, 第 2 作者  通讯作者  39: http://dx.doi.org/10.1016/j.cbd.2021.100827.
[20] Mohsen, Mohamed, Zhang, Libin, Sun, Lina, Lin, Chenggang, Wang, Qing, Liu, Shilin, Sun, Jinchun, Yang, Hongsheng. Effect of chronic exposure to microplastic fibre ingestion in the sea cucumber Apostichopus japonicus. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2021, 第 3 作者209: http://dx.doi.org/10.1016/j.ecoenv.2020.111794.
[21] Mohsen, Mohamed, Sun, Lina, Lin, Chenggang, Huo, Da, Yang, Hongsheng. Mechanism underlying the toxicity of the microplastic fibre transfer in the sea cucumber Apostichopus japonicus. JOURNAL OF HAZARDOUS MATERIALS[J]. 2021, 第 2 作者416: http://dx.doi.org/10.1016/j.jhazmat.2021.125858.
[22] 许帅, 孙景春, 刘石林, 林承刚, 张立斌, 孙丽娜, 杨红生. 棘皮动物精子超低温冷冻保存技术研究进展. 渔业科学进展[J]. 2021, 第 6 作者42(3): 26-37, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFDLAST2021&filename=HYSC202103003&v=MjY3ODg3RGgxVDNxVHJXTTFGckNVUjd1ZlllZG1GeTdtVXIzTkxUVFliYkc0SE5ETXJJOUZaNFI4ZVgxTHV4WVM=.
[23] Yang, Yujia, Li, Xiaoni, Sun, Lina. Triterpenoid saponin biosynthesis genes and their expression patterns during the development of sea cucumber Apostichopus japonicus. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2021, 第 3 作者  通讯作者  39(6): 2295-2308, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=7113383&detailType=1.
[24] Huo, Da, Sun, Lina, Sun, Jingchun, Zhang, Libin, Liu, Shilin, Su, Fang, Yang, Hongsheng. Sea cucumbers in a high temperature and low dissolved oxygen world: Roles of miRNAs in the regulation of environmental stresses. ENVIRONMENTAL POLLUTION[J]. 2021, 第 2 作者  通讯作者  268: http://dx.doi.org/10.1016/j.envpol.2020.115509.
[25] Da Huo, Lina Sun, Jingchun Sun, Chenggang Lin, Shilin Liu, Libin Zhang, Hongsheng Yang. Emerging roles of circRNAs in regulating thermal and hypoxic stresses in Apostichopus japonicus (Echinodermata: Holothuroidea). ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY[J]. 2021, 第 2 作者  通讯作者  228: 
[26] Xing, Lili, Sun, Lina, Liu, Shilin, Zhang, Libin, Yang, Hongsheng. Comparative metabolomic analysis of the body wall from four varieties of the sea cucumber Apostichopus japonicus. FOOD CHEMISTRY[J]. 2021, 第 2 作者352: http://dx.doi.org/10.1016/j.foodchem.2021.129339.
[27] Lin Chenggang, Liu Xiaolu, Sun Lina, Liu Shilin, Sun Jingchun, Zhang Libin, Yang Hongsheng. Effects of different flow velocities on behavior and TRPA1 expression in the sea cucumberApostichopus japonicas. JOURNAL OF OCEANOLOGY AND LIMNOLOGY[J]. 2020, 第 3 作者38(4): 1328-1340, http://lib.cqvip.com/Qikan/Article/Detail?id=7102292183.
[28] Liu, Xiaolu, Chenggang, Lin, Sun, Lina, Liu, Shilin, Sun, Jingchun, Yang, Hongsheng. Behavioural response of different epithelial tissues of sea cucumber (Apostichopus japonicus) to light and differential expression of the light-related genePax6. MARINE AND FRESHWATER BEHAVIOUR AND PHYSIOLOGY[J]. 2020, 第 3 作者53(2): 73-85, https://www.webofscience.com/wos/woscc/full-record/WOS:000567656800003.
[29] 杨红生, 孙景春, 茹小尚, 张灿影, 邢丽丽, 孙丽娜, 林承刚, 刘石林, 张立斌. 我国刺参种业态势分析与技术创新展望. 海洋科学[J]. 2020, 第 6 作者44(7): 2-9, http://qdhys.ijournal.cn/hykx/ch/reader/view_abstract.aspx?file_no=20200702&flag=1.
[30] Mohsen, Mohamed, Zhang, Libin, Sun, Lina, Lin, Chenggang, Wang, Qing, Yang, Hongsheng. Microplastic fibers transfer from the water to the internal fluid of the sea cucumber Apostichopus japonicus. ENVIRONMENTAL POLLUTION[J]. 2020, 第 3 作者257: http://dx.doi.org/10.1016/j.envpol.2019.113606.
[31] Xiaolu Liu, Chenggang Lin, Lina Sun, Shilin Liu, Jingchun Sun, Libin Zhang, Hongsheng Yang. Transcriptome analysis of phototransduction-related genes in tentacles of the sea cucumber Apostichopus japonicus. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY - PART D: GENOMICS AND PROTEOMICS. 2020, 第 3 作者34: http://dx.doi.org/10.1016/j.cbd.2020.100675.
[32] Zhang, Hongxia, Wang, Qing, Zhao, Jianmin, Liu, Shilin, Zhang, Libin, Zhao, Ye, Yang, Hongsheng, Sun, Lina. Quantitative microbiome profiling links microbial community variation to the intestine regeneration rate of the sea cucumber Apostichopus japonicus. GENOMICS[J]. 2020, 第 8 作者  通讯作者  112(6): 5012-5020, http://dx.doi.org/10.1016/j.ygeno.2020.09.017.
[33] Wang, Tianming, Cao, Zheng, Shen, Zhangfei, Yang, Jingwen, Chen, Xu, Yang, Zhen, Xu, Ke, Xiang, Xiaowei, Yu, Qiuhan, Song, Yimin, Wang, Weiwei, Tian, Yanan, Sun, Lina, Zhang, Libin, Guo, Su, Zhou, Naiming. Existence and functions of a kisspeptin neuropeptide signaling system in a non-chordate deuterostome species. ELIFE[J]. 2020, 第 13 作者9: https://doaj.org/article/dbed66ebd48648e886835c50c880eeff.
[34] Huo, Da, Sun, Lina, Storey, Kenneth B, Zhang, Libin, Liu, Shilin, Sun, Jingchun, Yang, Hongsheng. The regulation mechanism of lncRNAs and mRNAs in sea cucumbers under global climate changes: Defense against thermal and hypoxic stresses. SCIENCE OF THE TOTAL ENVIRONMENT[J]. 2020, 第 2 作者  通讯作者  709: http://dx.doi.org/10.1016/j.scitotenv.2019.136045.
[35] Liu, Xiaolu, Lin, Chenggang, Sun, Lina, Liu, Shilin, Sun, Jingchun, Zhang, Libin, Yang, Hongsheng. Transcriptome analysis of phototransduction-related genes in tentacles of the sea cucumber Apostichopus japonicus. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS[J]. 2020, 第 3 作者34: http://dx.doi.org/10.1016/j.cbd.2020.100675.
[36] Yang, Yujia, Zheng, Yingqiu, Sun, Lina, Chen, Muyan. Genome-Wide DNA Methylation Signatures of Sea CucumberApostichopus japonicusduring Environmental Induced Aestivation. GENES[J]. 2020, 第 3 作者  通讯作者  11(9): http://dx.doi.org/10.3390/genes11091020.
[37] Mohsen, Mohamed, Zhang, Libin, Sun, Lina, Lin, Chenggang, Liu, Shilin, Wang, Qing, Yang, Hongsheng. A deposit-feeder sea cucumber also ingests suspended particles through the mouth. JOURNAL OF EXPERIMENTAL BIOLOGY[J]. 2020, 第 3 作者223(24): https://www.webofscience.com/wos/woscc/full-record/WOS:000605472600010.
[38] Huo, Da, Sun, Lina, Zhang, Libin, Ru, Xiaoshang, Liu, Shilin, Yang, Hongsheng. Metabolome responses of the sea cucumber Apostichopus japonicus to multiple environmental stresses: Heat and hypoxia. MARINE POLLUTION BULLETIN[J]. 2019, 第 2 作者  通讯作者  138: 407-420, http://dx.doi.org/10.1016/j.marpolbul.2018.11.063.
[39] Ding, Kui, Zhang, Libin, Sun, Lina, Lin, Chenggang, Feng, Qiming, Zhang, Shuangyan, Yang, Hongsheng, Brinkman, Richard, Lin, Gang, Huang, Zhen. Transcriptome analysis provides insights into the molecular mechanisms responsible for evisceration behavior in the sea cucumber Apostichopus japonicus. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS[J]. 2019, 第 3 作者30: 143-157, http://dx.doi.org/10.1016/j.cbd.2019.02.008.
[40] Mohsen, Mohamed, Wang, Qing, Zhang, Libin, Sun, Lina, Lin, Chenggang, Yang, Hongsheng. Microplastic ingestion by the farmed sea cucumber Apostichopus japonicus in China. ENVIRONMENTAL POLLUTION[J]. 2019, 第 4 作者245: 1071-1078, http://dx.doi.org/10.1016/j.envpol.2018.11.083.
[41] Yang, MeiJie, Song, Hao, Sun, LiNa, Yu, ZhengLin, Hu, Zhi, Wang, XiaoLong, Zhu, JiaYi, Zhang, Tao. Effect of temperature on the microflora community composition in the digestive tract of the veined rapa whelk (Rapana venosa) revealed by 16S rRNA gene sequencing. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS[J]. 2019, 第 3 作者29: 145-153, http://ir.qdio.ac.cn/handle/337002/155292.
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（ 1 ） 刺参再生的基因组特征解析与关键调控基因分析, 负责人, 国家任务, 2018-01--2021-12
（ 2 ） 仿刺参生长与品质性状的遗传调控机制研究, 负责人, 国家任务, 2018-12--2022-12
（ 3 ） 青年创新促进会, 负责人, 中国科学院计划, 2019-01--2022-12
（ 4 ） 基于单细胞RNA-Seq技术分析刺参肠道再生原 基细胞的演化命运, 负责人, 国家任务, 2021-01--2024-12
（ 5 ） 中国科学院海洋研究所汇泉青年学者人才项目, 负责人, 研究所自选, 2019-11--2022-11
（ 6 ） 棘皮动物可变结缔组织可塑性的遗传基础与调控机制, 负责人, 国家任务, 2023-01--2026-12

已指导学生

崔玮  硕士研究生  085238-生物工程  

现指导学生

李金琪  硕士研究生  085700-资源与环境