基本信息
降雨强 男 博导 中国科学院遗传与发育生物学研究所
电子邮件: yqjiang@genetics.ac.cn
通信地址: 北辰西路1号院2号遗传发育所
邮政编码: 100101
电子邮件: yqjiang@genetics.ac.cn
通信地址: 北辰西路1号院2号遗传发育所
邮政编码: 100101
招生信息
招生专业
071011-生物物理学
071011-生物物理学
071011-生物物理学
招生方向
光镊技术及其生物学应用
微纳光学及生物影像技术开发与应用
纳米功能材料及生物学效应
微纳光学及生物影像技术开发与应用
纳米功能材料及生物学效应
教育背景
2001-09--2004-07 山西大学 博士
1998-09--2001-07 山西大学 硕士
1985-09--1989-07 北京师范大学 学士
1998-09--2001-07 山西大学 硕士
1985-09--1989-07 北京师范大学 学士
工作经历
工作简历
2012-05~现在, 遗传与发育生物学研究所, 研究员
2011-01~2012-05,华南师范大学, 教授
2007-05~2010-05,日本国立自然科学研究机构分子科学研究所, 博士后
2004-11~2007-03,大阪大学, 博士后
2001-09~2004-07,山西大学, 博士
1998-09~2001-07,山西大学, 硕士
1989-07~2004-11,山西大同大学, 助教,讲师,副教授
1985-09~1989-07,北京师范大学, 学士
2011-01~2012-05,华南师范大学, 教授
2007-05~2010-05,日本国立自然科学研究机构分子科学研究所, 博士后
2004-11~2007-03,大阪大学, 博士后
2001-09~2004-07,山西大学, 博士
1998-09~2001-07,山西大学, 硕士
1989-07~2004-11,山西大同大学, 助教,讲师,副教授
1985-09~1989-07,北京师范大学, 学士
出版信息
发表论文
(1) Highly luminescent gold nanoparticles prepared via a facile photochemical method for bioimaging applications, Advanced Composites and Hybrid Materials, 2024, 第 14 作者 通讯作者
(2) Calculation and measurement of trap stiffness in femtosecond optical tweezers, Optics Express, 2024, 第 6 作者 通讯作者
(3) Deep Learning Insights into the Dynamic Effects of Photodynamic Therapy on Cancer Cells, PHARMACEUTICS, 2024, 第 7 作者 通讯作者
(4) Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1, DEVELOPMENTAL CELL, 2023, 第 10 作者
(5) A Strategy for the Acquisition and Analysis of Image-Based Phenome in Rice during the Whole Growth Period, PLANT PHENOMICS, 2023, 第 9 作者
(6) Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters for efficient treatment of deep hypoxic solid tumors combined with enhanced antitumor immune response, THERANOSTICS, 2023, 第 11 作者 通讯作者
(7) Generation of Optical Vortices by Diffraction from Circular Apertures, ACS PHOTONICS, 2023, 第 7 作者 通讯作者
(8) Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis, Science Bulletin, 2022, 第 12 作者
(9) 小胶质细胞在双环己酮草酰二腙诱导的急性脱髓鞘小鼠模型中的动态变化及意义, The changes and significance of microglia in acute demyelination mice model mediated by cuprizone, 中国神经免疫学和神经病学杂志, 2021, 第 10 作者
(10) Nonlinearity-induced nanoparticle circumgyration at sub-diffraction scale, NATURE COMMUNICATIONS, 2021, 第 11 作者 通讯作者
(11) Spheroidal trap shell beyond diffraction limit induced by nonlinear effects in femtosecond laser trapping, NANOPHOTONICS, 2020, 第 7 作者 通讯作者
(12) Postsynaptic cAMP signalling regulates the antagonistic balance of Drosophila glutamate receptor subtypes, DEVELOPMENT, 2020, 第 7 作者
(13) Super-efficient in Vivo Two-Photon Photodynamic Therapy with a Gold Nanocluster as a Type I Photosensitizer, ACS NANO, 2020, 第 11 作者 通讯作者
(14) Fine features of optical potential well induced by nonlinearity, OPTICS LETTERS, 2020, 第 4 作者
(15) Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms, METABOLIC BRAIN DISEASE, 2019, 第 10 作者 通讯作者
(16) Nonlinearity-Induced Multiplexed Optical Trapping and Manipulation with Femtosecond Vector Beams, NANO LETTERS, 2018, 第 5 作者
(17) Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer's Disease-Related Changes Through the Regulation of the Peripheral Immune System, FRONTIERS IN AGING NEUROSCIENCE, 2018, 第 14 作者 通讯作者
(18) dTBC1D7 regulates systemic growth independently of TSC through insulin signaling, JOURNAL OF CELL BIOLOGY, 2018, 第 3 作者
(19) 法舒地尔通过促进APP/PS1双转基因小鼠神经再生改善认知功能, Rho kinase inhibitor fasudil improves cognitive function by promoting nerve regeneration in APP/PS1 double transgenic mice, 中国病理生理杂志, 2018, 第 12 作者
(20) CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells, JOURNAL OF GENETICS AND GENOMICS, 2017, 第 3 作者
(21) 法舒地尔通过抑制脑内小胶质细胞活化并促进其M2极化而改善APP/PS1双转基因小鼠认知功能, Fasudil improves cognition of APP/PS1 transgenic mice via inhibiting the activation of microglia and shifting microglia phenotypes from M1 to M2, 细胞与分子免疫学杂志, 2017, 第 12 作者
(22) PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila, CELL DEATH & DISEASE, 2016,
(23) Nanoprobes for two-photon excitation time-resolved imaging of living animals: In situ analysis of tumor-targeting dynamics of nanocarriers, BIOMATERIALS, 2016, 第 11 作者
(24) Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging, SCIENTIFIC REPORTS, 2015, 第 7 作者 通讯作者
(25) Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength, SCIENTIFIC REPORTS, 2015, 第 8 作者
(26) Two-Photon Luminescence and Second Harmonic Generation from Gold Micro-Plates, SENSORS (BASEL, SWITZERLAND), 2014, 第 7 作者
(27) Two-Photon Luminescence and Second Harmonic Generation from Gold Micro-Plates, SENSORS, 2014, 第 7 作者 通讯作者
(28) En face optical coherence tomography of transient light response at photoreceptor outer segments in living frog eyecup, OPTICS LETTERS, 2013, 第 4 作者
(29) Recent Advances in Super-Resolution Fluorescence Imaging and Its Applications in Biology, JOURNAL OF GENETICS AND GENOMICS, 2013, 第 4 作者 通讯作者
(30) Proposal of a wavelength filter with a cut corner based on Equilateral-Triangle-Resonator, OPTICS EXPRESS, 2013, 第 4 作者
(31) Nonlinear optical effects in trapping nanoparticles with femtosecond pulses, NATURE PHYSICS, 2010, 第 1 作者
(32) SECONDARY CONVERGENCE IN FEMTOSECOND LASER TRAPPING, MODERN PHYSICS LETTERS B, 2010, 第 1 作者 通讯作者
(33) Bioimaging with Two-Photon-Induced Luminescence from Triangular Nanoplates and Nanoparticle Aggregates of Gold, ADVANCED MATERIALS, 2009, 第 1 作者
(34) Spatial light modulating and multi-trapping with a DMD, MODERN PHYSICS LETTERS B, 2007, 第 1 作者 通讯作者
(35) Trapping and manipulation of a single micro-object in solution with femtosecond laser-induced mechanical force, APPLIED PHYSICS LETTERS, 2007, 第 1 作者 通讯作者
(36) Influence of illumination conditions on the measurement of optical tweezers system, INTERNATIONAL JOURNAL OF MODERN PHYSICS B, 2006,
(37) 单光子探测用于光子统计测量的研究, 科学通报, 2004, 第 5 作者
(38) He-Ne激光照射对兔血液携氧能力影响的实验研究, The Experimental Investigation to the Influence of He-Ne Laser Irradiation on the Rabbit Blood Carrying Oxygen, 中国医学物理学杂志, 2004, 第 1 作者
(39) 单光子探测用于光子统计测量的研究, 中国养蜂, 2004, 第 2 作者
(40) He—Ne激光照射对血液及其组分荧光光谱影响的实验研究, The experimental investigation of the fluorescent spectra of human blood and its components, 生物物理学报, 2003, 第 1 作者
(41) He—Ne激光照射对正常与HBsAg阳性血液荧光光谱的影响, 中国激光医学杂志, 2002, 第 1 作者
(42) 低强度激光血管内照射治疗的机理初探, 激光生物学报, 2001, 第 5 作者
(43) 人血液及其组分的荧光光谱研究, 激光与光电子学进展, 2001, 第 5 作者
(2) Calculation and measurement of trap stiffness in femtosecond optical tweezers, Optics Express, 2024, 第 6 作者 通讯作者
(3) Deep Learning Insights into the Dynamic Effects of Photodynamic Therapy on Cancer Cells, PHARMACEUTICS, 2024, 第 7 作者 通讯作者
(4) Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1, DEVELOPMENTAL CELL, 2023, 第 10 作者
(5) A Strategy for the Acquisition and Analysis of Image-Based Phenome in Rice during the Whole Growth Period, PLANT PHENOMICS, 2023, 第 9 作者
(6) Low-dose X-ray radiodynamic therapy solely based on gold nanoclusters for efficient treatment of deep hypoxic solid tumors combined with enhanced antitumor immune response, THERANOSTICS, 2023, 第 11 作者 通讯作者
(7) Generation of Optical Vortices by Diffraction from Circular Apertures, ACS PHOTONICS, 2023, 第 7 作者 通讯作者
(8) Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis, Science Bulletin, 2022, 第 12 作者
(9) 小胶质细胞在双环己酮草酰二腙诱导的急性脱髓鞘小鼠模型中的动态变化及意义, The changes and significance of microglia in acute demyelination mice model mediated by cuprizone, 中国神经免疫学和神经病学杂志, 2021, 第 10 作者
(10) Nonlinearity-induced nanoparticle circumgyration at sub-diffraction scale, NATURE COMMUNICATIONS, 2021, 第 11 作者 通讯作者
(11) Spheroidal trap shell beyond diffraction limit induced by nonlinear effects in femtosecond laser trapping, NANOPHOTONICS, 2020, 第 7 作者 通讯作者
(12) Postsynaptic cAMP signalling regulates the antagonistic balance of Drosophila glutamate receptor subtypes, DEVELOPMENT, 2020, 第 7 作者
(13) Super-efficient in Vivo Two-Photon Photodynamic Therapy with a Gold Nanocluster as a Type I Photosensitizer, ACS NANO, 2020, 第 11 作者 通讯作者
(14) Fine features of optical potential well induced by nonlinearity, OPTICS LETTERS, 2020, 第 4 作者
(15) Therapeutic potentials of the Rho kinase inhibitor Fasudil in experimental autoimmune encephalomyelitis and the related mechanisms, METABOLIC BRAIN DISEASE, 2019, 第 10 作者 通讯作者
(16) Nonlinearity-Induced Multiplexed Optical Trapping and Manipulation with Femtosecond Vector Beams, NANO LETTERS, 2018, 第 5 作者
(17) Fasudil in Combination With Bone Marrow Stromal Cells (BMSCs) Attenuates Alzheimer's Disease-Related Changes Through the Regulation of the Peripheral Immune System, FRONTIERS IN AGING NEUROSCIENCE, 2018, 第 14 作者 通讯作者
(18) dTBC1D7 regulates systemic growth independently of TSC through insulin signaling, JOURNAL OF CELL BIOLOGY, 2018, 第 3 作者
(19) 法舒地尔通过促进APP/PS1双转基因小鼠神经再生改善认知功能, Rho kinase inhibitor fasudil improves cognitive function by promoting nerve regeneration in APP/PS1 double transgenic mice, 中国病理生理杂志, 2018, 第 12 作者
(20) CAMSAP3-dependent microtubule dynamics regulates Golgi assembly in epithelial cells, JOURNAL OF GENETICS AND GENOMICS, 2017, 第 3 作者
(21) 法舒地尔通过抑制脑内小胶质细胞活化并促进其M2极化而改善APP/PS1双转基因小鼠认知功能, Fasudil improves cognition of APP/PS1 transgenic mice via inhibiting the activation of microglia and shifting microglia phenotypes from M1 to M2, 细胞与分子免疫学杂志, 2017, 第 12 作者
(22) PINK1 and Parkin cooperatively protect neurons against constitutively active TRP channel-induced retinal degeneration in Drosophila, CELL DEATH & DISEASE, 2016,
(23) Nanoprobes for two-photon excitation time-resolved imaging of living animals: In situ analysis of tumor-targeting dynamics of nanocarriers, BIOMATERIALS, 2016, 第 11 作者
(24) Extremely High Brightness from Polymer-Encapsulated Quantum Dots for Two-photon Cellular and Deep-tissue Imaging, SCIENTIFIC REPORTS, 2015, 第 7 作者 通讯作者
(25) Intracellular Temperature Sensing: An Ultra-bright Luminescent Nanothermometer with Non-sensitivity to pH and Ionic Strength, SCIENTIFIC REPORTS, 2015, 第 8 作者
(26) Two-Photon Luminescence and Second Harmonic Generation from Gold Micro-Plates, SENSORS (BASEL, SWITZERLAND), 2014, 第 7 作者
(27) Two-Photon Luminescence and Second Harmonic Generation from Gold Micro-Plates, SENSORS, 2014, 第 7 作者 通讯作者
(28) En face optical coherence tomography of transient light response at photoreceptor outer segments in living frog eyecup, OPTICS LETTERS, 2013, 第 4 作者
(29) Recent Advances in Super-Resolution Fluorescence Imaging and Its Applications in Biology, JOURNAL OF GENETICS AND GENOMICS, 2013, 第 4 作者 通讯作者
(30) Proposal of a wavelength filter with a cut corner based on Equilateral-Triangle-Resonator, OPTICS EXPRESS, 2013, 第 4 作者
(31) Nonlinear optical effects in trapping nanoparticles with femtosecond pulses, NATURE PHYSICS, 2010, 第 1 作者
(32) SECONDARY CONVERGENCE IN FEMTOSECOND LASER TRAPPING, MODERN PHYSICS LETTERS B, 2010, 第 1 作者 通讯作者
(33) Bioimaging with Two-Photon-Induced Luminescence from Triangular Nanoplates and Nanoparticle Aggregates of Gold, ADVANCED MATERIALS, 2009, 第 1 作者
(34) Spatial light modulating and multi-trapping with a DMD, MODERN PHYSICS LETTERS B, 2007, 第 1 作者 通讯作者
(35) Trapping and manipulation of a single micro-object in solution with femtosecond laser-induced mechanical force, APPLIED PHYSICS LETTERS, 2007, 第 1 作者 通讯作者
(36) Influence of illumination conditions on the measurement of optical tweezers system, INTERNATIONAL JOURNAL OF MODERN PHYSICS B, 2006,
(37) 单光子探测用于光子统计测量的研究, 科学通报, 2004, 第 5 作者
(38) He-Ne激光照射对兔血液携氧能力影响的实验研究, The Experimental Investigation to the Influence of He-Ne Laser Irradiation on the Rabbit Blood Carrying Oxygen, 中国医学物理学杂志, 2004, 第 1 作者
(39) 单光子探测用于光子统计测量的研究, 中国养蜂, 2004, 第 2 作者
(40) He—Ne激光照射对血液及其组分荧光光谱影响的实验研究, The experimental investigation of the fluorescent spectra of human blood and its components, 生物物理学报, 2003, 第 1 作者
(41) He—Ne激光照射对正常与HBsAg阳性血液荧光光谱的影响, 中国激光医学杂志, 2002, 第 1 作者
(42) 低强度激光血管内照射治疗的机理初探, 激光生物学报, 2001, 第 5 作者
(43) 人血液及其组分的荧光光谱研究, 激光与光电子学进展, 2001, 第 5 作者
科研活动
科研项目
( 1 ) 精子的自动优选技术及相关设备的研发, 负责人, 地方任务, 2018-01--2020-12
( 2 ) 精子的自动优选技术及相关设备的研发, 负责人, 境内委托项目, 2017-05--2019-05
( 3 ) 飞秒激光捕获中势阱劈裂的三维分布, 负责人, 国家任务, 2017-01--2020-12
( 4 ) 光电力融合生物微操纵与检测综合实验平台, 负责人, 中国科学院计划, 2012-11--2014-10
( 5 ) 飞秒激光捕获和操纵金属纳米颗粒过程中的非线性效应及其应用的研究, (11174089), 负责人, 国家任务, 2012-01--2015-12
( 6 ) 轴对称偏振光束基础研究及其应用,(61138003), 负责人, 国家任务, 2012-01--2016-12
( 7 ) 用于生物双光子荧光精确示踪与成像的金纳米材料, 负责人, 地方任务, 2011-11--2014-10
( 8 ) 基于非线性极化作用的光学微操纵技术及其应用的研究, 负责人, 地方任务, 2011-10--2014-09
( 2 ) 精子的自动优选技术及相关设备的研发, 负责人, 境内委托项目, 2017-05--2019-05
( 3 ) 飞秒激光捕获中势阱劈裂的三维分布, 负责人, 国家任务, 2017-01--2020-12
( 4 ) 光电力融合生物微操纵与检测综合实验平台, 负责人, 中国科学院计划, 2012-11--2014-10
( 5 ) 飞秒激光捕获和操纵金属纳米颗粒过程中的非线性效应及其应用的研究, (11174089), 负责人, 国家任务, 2012-01--2015-12
( 6 ) 轴对称偏振光束基础研究及其应用,(61138003), 负责人, 国家任务, 2012-01--2016-12
( 7 ) 用于生物双光子荧光精确示踪与成像的金纳米材料, 负责人, 地方任务, 2011-11--2014-10
( 8 ) 基于非线性极化作用的光学微操纵技术及其应用的研究, 负责人, 地方任务, 2011-10--2014-09
参与会议
(1)Nonlinear Optical Effects in Optical Trapping with Femtosecond Laser Yuqiang Jiang; Hao Shi; Lianghui Cheng 2013-04-14