基本信息
吴婉莹 女 博导 中国科学院上海药物研究所
电子邮件: wanyingwu@simm.ac.cn
通信地址: 上海浦东新区海科路501号
邮政编码: 201203
电子邮件: wanyingwu@simm.ac.cn
通信地址: 上海浦东新区海科路501号
邮政编码: 201203
招生信息
招生专业
100704-药物分析学
招生方向
出版信息
发表论文
[1] Wu, Jia, Yang, Wenzhi, Pan, Huiqin, Yao, Shuai, Wu, Wanying, Guo, Dean. Geographic impact evaluation of the quality of Alismatis Rhizoma by untargeted metabolomics and quantitative assay. JOURNAL OF SEPARATION SCIENCE[J]. 2018, 41(4): 839-846, https://www.webofscience.com/wos/woscc/full-record/WOS:000425741100004.[2] Yao, Changliang, Pan, Huiqin, Wang, Hui, Yao, Shuai, Yang, Wenzhi, Hou, Jinjun, Jin, Qinghao, Wu, Wanying, Guo, Dean. Global profiling combined with predicted metabolites screening for discovery of natural compounds: Characterization of ginsenosides in the leaves of Panax notoginseng as a case study. JOURNAL OF CHROMATOGRAPHY A[J]. 2018, 1538: 34-44, http://dx.doi.org/10.1016/j.chroma.2018.01.040.[3] Shi Xiaojian, Yang Wenzhi, Qiu Shi, Yao Changliang, Shen Yao, Pan Huiqin, Bi Qirui, Yang Min, Wu Wanying, Guo Dean. An in-source multiple collision-neutral loss filtering based nontargeted metabolomics approach for the comprehensive analysis of malonyl-ginsenosides from Panax ginseng , P. quinquefolius , and P. notoginseng. ANALYTICA CHIMICA ACTA[J]. 2017, [4] Yao, Changliang, Yang, Wenzhi, Zhang, Jingxian, Qiu, Shi, Chen, Ming, Shi, Xiaojian, Pan, Huiqin, Wu, Wanying, Guo, Dean. UHPLC-Q-TOF-MS-based metabolomics approach to compare the saponin compositions of Xueshuantong injection and Xuesaitong injection. JOURNAL OF SEPARATION SCIENCE[J]. 2017, 40(4): 834-841, [5] Shen, Yao, Hou, Jinjun, Deng, Wen, Feng, Zijin, Yang, Min, Cheng, Jinle, Wu, Wanying, Guo, Dean. Comparative Analysis of Ultrafine Granular Powder and Decoction Pieces of Salvia miltiorrhiza by UPLC-UV-MSn Combined with Statistical Analysis. PLANTA MEDICA[J]. 2017, 83(6): 557-564, https://www.webofscience.com/wos/woscc/full-record/WOS:000399325400008.[6] Yang, Wenzhi, Zhang, Yibei, Pan, Huiqin, Yao, Changliang, Hou, Jinjun, Yao, Shuai, Cai, Luying, Feng, Ruihong, Wu, Wanying, Guo, Dean. Supercritical fluid chromatography for separation and preparation of tautomeric 7-epimeric spiro oxindole alkaloids from Uncaria macrophylla. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2017, 134: 352-360, http://dx.doi.org/10.1016/j.jpba.2016.10.021.[7] Qiu Shi, Yang WenZhi, Yao ChangLiang, Shi XiaoJian, Li JingYa, Lou Yang, Duan YaNan, Wu WanYing, Guo DeAn. Malonylginsenosides with Potential Antidiabetic Activities from the Flower Buds of Panax ginseng. JOURNAL OF NATURAL PRODUCTS[J]. 2017, [8] Yao, Changliang, Yang, Wenzhi, Si, Wei, Shen, Yao, Zhang, Naixia, Chen, Huali, Pan, Huiqin, Yang, Min, Wu, Wanying, Guo, Dean. An enhanced targeted identification strategy for the selective identification of flavonoid O-glycosides from Carthamus tinctorius by integrating offline two-dimensional liquid chromatography/linear ion-trap-Orbitrap mass spectrometry, high-resolution diagnostic product ions/neutral loss filtering and liquid chromatography-solid phase extraction-nuclear magnetic resonance. JOURNAL OF CHROMATOGRAPHY A[J]. 2017, 1491: 87-97, http://dx.doi.org/10.1016/j.chroma.2017.02.041.[9] Wang Jianwei, Qi Peng, Hou Jinjun, Shen Yao, Yang Min, Bi Qirui, Deng Yanping, Shi Xiaojian, Feng Ruihong, Feng Zijin, Wu Wanying, Guo Dean. The profiling of the metabolites of hirsutine in rat by ultra-high performance liquid chromatography coupled with linear ion trap Orbitrap mass spectrometry: An improved strategy for the systematic screening and identification of metabolites in multi-samples in vivo. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2017, [10] Wan-ying Wu. New monoterpenoid oxindole alkaloid derivatives from the stems of Uncaria hirsuta Hvail. and their cytotoxicity and tandem mass spectrometric fragmentation,. Fitoterapia.. 2017, [11] Zhang, JingXian, Li, ShangRong, Yao, Shuai, Bi, QiRui, Hou, JinJun, Cai, LuYing, Han, SuMei, Wu, WanYing, Guo, DeAn. Anticonvulsant and sedative-hypnotic activity screening of pearl and nacre (mother of pearl). JOURNAL OF ETHNOPHARMACOLOGY[J]. 2016, 181: 229-235, http://dx.doi.org/10.1016/j.jep.2016.01.039.[12] Yang, Wenzhi, Si, Wei, Zhang, Jingxian, Yang, Min, Pan, Huiqin, Wu, Jia, Qiu, Shi, Yao, Changliang, Hou, Jinjun, Wu, Wanying, Guo, Dean. Selective and comprehensive characterization of the quinochalcone C-glycoside homologs in Carthamus tinctorius L. by offline comprehensive two-dimensional liquid chromatography/LTQ-Orbitrap MS coupled with versatile data mining strategies. RSC ADVANCES[J]. 2016, 6(1): 495-506, https://www.webofscience.com/wos/woscc/full-record/WOS:000367250900060.[13] Long HuaLi, Zhang JingXian, Guo JiLing, Sui GuoQi, Hou JinJun, Yang WenZhi, Han SuMei, Wu WanYing, Guo DeAn. Development of specific and quantitative methods for the quality control of the polysaccharides from sea-tangle and sargassum. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2016, 14(12): 954-960, http://dx.doi.org/10.1016/S1875-5364(17)30022-5.[14] Wan-ying Wu. A strategy combining higher energy C-trap dissociation with neutral loss- and product ion- based MSn acquisition for global profiling and structure annotation of fatty acids conjugates. J. Am Soc Mass Spectr.. 2016, [15] Yao, Changliang, Yang, Wenzhi, Si, Wei, Pan, Huiqin, Qiu, Shi, Wu, Jia, Shi, Xiaojian, Feng, Ruihong, Wu, Wanying, Guo, Dean. A strategy for establishment of practical identification methods for Chinese patent medicine from systematic multi-component characterization to selective ion monitoring of chemical markers: Shuxiong tablet as a case study. RSC ADVANCES[J]. 2016, 6(69): 65055-65066, http://www.corc.org.cn/handle/1471x/2374743.[16] Bi Qirui, Hou Jinjun, Qi Peng, Ma Chunhua, Shen Yao, Feng Ruihong, Yan Bingpeng, Wang Jianwei, Shi Xiaojian, Zheng Yuanyuan, Wu Wanying, Guo Dean. Venenum Bufonis induces rat neuroinflammation by activiating NF-κB pathway and attenuation of BDNF. JOURNAL OF ETHNOPHARMACOLOGY[J]. 2016, [17] Wan-ying Wu. TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats. Sci Rep.. 2016, [18] Zhang, Jingxian, Yang, Wenzhi, Li, Shangrong, Yao, Shuai, Qi, Peng, Yang, Zhou, Feng, Zijin, Hou, Jinjun, Cai, Luying, Yang, Min, Wu, Wanying, Guo, Dean. An intelligentized strategy for endogenous small molecules characterization and quality evaluation of earthworm from two geographic origins by ultra-high performance HILIC/QTOF MSE and Progenesis QI. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2016, 408(14): 3881-3890, https://www.webofscience.com/wos/woscc/full-record/WOS:000375057400021.[19] Wang, Jianwei, Qi, Peng, Hou, Jinjun, Shen, Yao, Yan, Bingpeng, Bi, Qirui, Feng, RuiHong, Shi, Xiaojian, Yang, Min, Wu, Wanying, Guo, Dean. Profiling and identification of metabolites of isorhynchophylline in rats by ultra high performance liquid chromatography and linear ion trap Orbitrap mass spectrometry. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES[J]. 2016, 1033: 147-156, http://dx.doi.org/10.1016/j.jchromb.2016.08.013.[20] Zhang DongMei, Feng LiXing, Li Lu, Liu Miao, Jiang BaoHong, Yang Min, Li GuoQiang, Wu WanYing, Guo DeAn, Liu Xuan. Nano-LC-ESI MS/MS analysis of proteins in dried sea dragon Solenognathus hardwickii and bioinformatic analysis of its protein expression profiling. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2016, 14(9): 709-713, http://dx.doi.org/10.1016/S1875-5364(16)30084-X.[21] Qiu, Shi, Yang, Wenzhi, Yao, Changliang, Qiu, Zhidong, Shi, Xiaojian, Zhang, Jingxian, Hou, Jinjun, Wang, Qiurong, Wu, Wanying, Guo, Dean. Nontargeted metabolomic analysis and "commercial-homophyletic" comparison-induced biomarkers verification for the systematic chemical differentiation of five different parts of Panax ginseng. JOURNAL OF CHROMATOGRAPHY A[J]. 2016, 1453: 78-87, http://dx.doi.org/10.1016/j.chroma.2016.05.051.[22] Yang, Wenzhi, Zhang, Jingxian, Yao, Changliang, Qiu, Shi, Chen, Ming, Pan, Huiqin, Shi, Xiaojian, Wu, Wanying, Guo, Dean. Method development and application of offline two-dimensional liquid chromatography/quadrupole time-of-flight mass spectrometry-fast data directed analysis for comprehensive characterization of the saponins from Xueshuantong Injection. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2016, 128: 322-332, http://dx.doi.org/10.1016/j.jpba.2016.05.035.[23] Yao, Shuai, Zhang, Jingxian, Wang, Dandan, Hou, Jinjun, Yang, Wenzhi, Da, Juan, Cai, Luying, Yang, Min, Jiang, Baohong, Liu, Xuan, Guo, Dean, Wu, Wanying. Discriminatory Components Retracing Strategy for Monitoring the Preparation Procedure of Chinese Patent Medicines by Fingerprint and Chemometric Analysis. PLOS ONE[J]. 2015, 10(3): https://doaj.org/article/b58e9cce93cc4df8b43cae03943dfffc.[24] Da, Juan, Cheng, ChunRu, Yao, Shuai, Long, HuaLi, Wang, YanHong, Khan, Ikhlas A, Li, YiFeng, Wang, QiuRong, Cai, LuYing, Jiang, BaoHong, Liu, Xuan, Wu, WanYing, Guo, DeAn. A reproducible analytical system based on the multi-component analysis of triterpene acids in Ganoderma lucidum. PHYTOCHEMISTRY[J]. 2015, 114: 146-154, http://dx.doi.org/10.1016/j.phytochem.2014.08.007.[25] Rui-Hong Feng, Jin-Jun Hou, Yi-Bei Zhang, Hui-Qin Pan, Peng Qi, Shuai Yao, Lu-Ying Cai, Min Yang, Baohong Jiang, Xuan Liu, Wan-Ying Wu, De-An Guo. AN EFFICIENT AND TARGET-ORIENTED SAMPLE ENRICHMENT METHOD FOR PREPARATIVE SEPARATION OF MINOR ALKALOIDS BY PH-ZONE-REFINING COUNTER-CURRENT CHROMATOGRAPHY. 世界中医药杂志英文版[J]. 2015, 104-105, http://lib.cqvip.com/Qikan/Article/Detail?id=87748467504849534852494953.[26] Pan, Huiqin, Yang, Wenzhi, Zhang, Yibei, Yang, Min, Feng, Ruihong, Wu, Wanying, Guo, Dean. An integrated strategy for the systematic characterization and discovery of new indole alkaloids from Uncaria rhynchophylla by UHPLC/DAD/LTQ-Orbitrap-MS. ANALYTICAL AND BIOANALYTICAL CHEMISTRY[J]. 2015, 407(20): 6057-6070, https://www.webofscience.com/wos/woscc/full-record/WOS:000358371200019.[27] Yao, Changliang, Yang, Wenzhi, Wu, Wanying, Da, Juan, Hou, Jinjun, Zhang, Jingxian, Zhang, Yanhai, Jin, Yan, Yang, Min, Jiang, Baohong, Liu, Xuan, Guo, Dean. Simultaneous quantitation of five Panax notoginseng saponins by multi heart-cutting two-dimensional liquid chromatography: Method development and application to the quality control of eight Notoginseng containing Chinese patent medicines. JOURNAL OF CHROMATOGRAPHY A[J]. 2015, 1402: 71-81, http://dx.doi.org/10.1016/j.chroma.2015.05.015.[28] 李尚蓉, 张静娴, 姚帅, 果德安, 吴婉莹. 珍珠和珍珠母的微量元素测定及其比较分析. 世界中医药[J]. 2015, 1594-1597, http://lib.cqvip.com/Qikan/Article/Detail?id=666725758.[29] Qiu, Shi, Yang, Wenzhi, Shi, Xiaojian, Yao, Changliang, Yang, Min, Liu, Xuan, Jiang, Baohong, Wu, Wanying, Guo, Dean. A green protocol for efficient discovery of novel natural compounds: Characterization of new ginsenosides from the stems and leaves of Panax ginseng as a case study. ANALYTICA CHIMICA ACTA[J]. 2015, 893: 65-76, http://dx.doi.org/10.1016/j.aca.2015.08.048.[30] Zhang, Jingxian, Li, Shangrong, Yao, Shuai, Si, Wei, Cai, Luying, Pan, Huiqin, Hou, Jinjun, Yang, Wenzhi, Da, Juan, Jiang, Baohong, Liu, Xuan, Wu, Wanying, Guo, Dean. Ultra-performance liquid chromatography of amino acids for the quality assessment of pearl powder. JOURNAL OF SEPARATION SCIENCE[J]. 2015, 38(9): 1552-1560, https://www.webofscience.com/wos/woscc/full-record/WOS:000354371500015.[31] Yan, Bingpeng, Deng, Yanping, Hou, Jinjun, Bi, Qirui, Yang, Min, Jiang, Baohong, Liu, Xuan, Wu, Wanying, Guo, Dean. UHPLC-LTQ-Orbitrap MS combined with spike-in method for plasma metabonomics analysis of acute myocardial ischemia rats and pretreatment effect of Danqi Tongmai tablet. MOLECULAR BIOSYSTEMS[J]. 2015, 11(2): 486-496, https://www.webofscience.com/wos/woscc/full-record/WOS:000348211900016.[32] Yang, W Z, Wu, W Y, Yang, M, Guo, D A. Elucidation of the fragmentation pathways of a complex 3, 7-O-glycosyl flavonol by CID, HCD and PQD on an LTQ-Orbitrap Velos Pro hybrid mass spectrometer. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2015, 13(11): 867-872, http://dx.doi.org/10.1016/S1875-5364(15)30091-1.[33] 司玮, 阿如娜, 李尚蓉, 张静娴, 吴婉莹, 崔亚君. 7种海洋矿物药的比较分析研究. 中国中药杂志[J]. 2014, 39(17): 3321-, http://lib.cqvip.com/Qikan/Article/Detail?id=662334260.[34] Zhang, Yibei, Yang, Wenzhi, Yao, Changliang, Feng, Ruihong, Yang, Min, Guo, Dean, Wu, Wanying. New triterpenic acids from Uncaria rhynchophylla: Chemistry, NO-inhibitory activity, and tandem mass spectrometric analysis. FITOTERAPIA[J]. 2014, 96: 39-47, http://dx.doi.org/10.1016/j.fitote.2014.04.004.[35] Hou, JinJun, Wu, WanYing, Liang, Jian, Yang, Zhou, Long, HuaLi, Cai, LuYing, Fang, Lin, Wang, DanDan, Yao, Shuai, Liu, Xuan, Jiang, BaoHong, Guo, DeAn. A single, multi-faceted, enhanced strategy to quantify the chromatographically diverse constituents in the roots of Euphorbia kansui. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2014, 88: 321-330, http://dx.doi.org/10.1016/j.jpba.2013.08.049.[36] Wv WanYing, Hou JinJun, Long HuaLi, Yang WenZhi, Mang Jian, Guo DeAn. TCM-based new drug discovery and development in China. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2014, 12(4): 241-250, http://dx.doi.org/10.1016/S1875-5364(14)60050-9.[37] 吴婉莹, 果德安. 中药整体质量控制标准体系构建的思路与方法. 中国中药杂志[J]. 2014, 39(3): 351-, https://kns.cnki.net/KCMS/detail/detail.aspx?dbcode=CJFQ&dbname=CJFD2014&filename=ZGZY201403001&v=MTMwMjU3RzRIOVhNckk5RlpZUjhlWDFMdXhZUzdEaDFUM3FUcldNMUZyQ1VSN3FmYitabUZ5dm1WYnpJUHlyUmQ=.[38] Wang, Dandan, Liang, Jian, Yang, Wenzhi, Hou, Jinjun, Yang, Min, Da, Juan, Wang, Ying, Jiang, Baohong, Liu, Xuan, Wu, Wanying, Guo, DeAn. HPLC/qTOF-MS-oriented characteristic components data set and chemometric analysis for the holistic quality control of complex TCM preparations: Niuhuang Shangqing pill as an example. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS[J]. 2014, 89: 130-141, http://dx.doi.org/10.1016/j.jpba.2013.10.042.[39] Liang, Jian, Wu, Wanying, Sun, Guoxiang, Wang, Dandan, Hou, Jinjun, Yang, Wenzhi, Jiang, Baohong, Liu, Xuan, Guo, Dean. A dynamic multiple reaction monitoring method for the multiple components quantification of complex traditional Chinese medicine preparations: Niuhuang Shangqing pill as an example. JOURNAL OF CHROMATOGRAPHY A[J]. 2013, 1294: 58-69, http://dx.doi.org/10.1016/j.chroma.2013.04.016.[40] Da, Juan, Wu, WanYing, Hou, JinJun, Long, HuaLi, Yao, Shuai, Yang, Zhou, Cai, LuYing, Yang, Min, Jiang, BaoHong, Liu, Xuan, Cheng, ChunRu, Li, YiFeng, Guo, DeAn. Comparison of two officinal Chinese pharmacopoeia species of Ganoderma based on chemical research with multiple technologies and chemometrics analysis. JOURNAL OF CHROMATOGRAPHY A[J]. 2012, 1222: 59-70, http://dx.doi.org/10.1016/j.chroma.2011.12.017.[41] Wang, WenBo, Feng, LiXing, Yue, QingXi, Wu, WanYing, Guan, ShuHong, Jiang, BaoHong, Yang, Min, Liu, Xuan, Guo, DeAn. Paraptosis accompanied by autophagy and apoptosis was induced by celastrol, a natural compound with influence on proteasome, ER stress and Hsp90. JOURNAL OF CELLULAR PHYSIOLOGY[J]. 2012, 227(5): 2196-2206, https://www.webofscience.com/wos/woscc/full-record/WOS:000299373900046.[42] Liu, Xuan, Wang, Yingchun, Ma, Chao, Zhang, Lin, Wu, Wanying, Guan, Shuhong, Yang, Min, Wang, Junchen, Jiang, Baohong, Guo, DeAn. Proteomic Assessment of Tanshinone II A Sodium Sulfonate on Doxorubicin Induced Nephropathy. AMERICAN JOURNAL OF CHINESE MEDICINE[J]. 2011, 39(2): 395-409, https://www.webofscience.com/wos/woscc/full-record/WOS:000289154800015.[43] Hou, JinJun, Wu, WanYing, Da, Juan, Yao, Shuai, Long, HuaLi, Yang, Zhou, Cai, LuYing, Yang, Min, Liu, Xuan, Jiang, BaoHong, Guo, DeAn. Ruggedness and robustness of conversion factors in method of simultaneous determination of multi-components with single reference standard. JOURNAL OF CHROMATOGRAPHY A[J]. 2011, 1218(33): 5618-5627, http://dx.doi.org/10.1016/j.chroma.2011.06.058.[44] Wan-ying Wu. Research and development of Qingnao capsule of TCM using the SFE technique. Mode Tradit Chin Med Mater Med. 2010, [45] Wan-ying Wu. Tanshinone IIA increase mRNA expression of efflux transporters in cultured human intestinal cell. Am J Chin Med. 2010, [46] Wan-ying Wu. Proteomic analysis of differential protein expression in rat platelets treated with notoginsengnosides. Phytomedicine. Planta Med. 2009, [47] Jiang, Baohong, Zhang, Lin, Wang, Yingchun, Li, Ming, Wu, Wanying, Guan, Shuhong, Liu, Xuan, Yang, Min, Wang, Junchen, Guo, Dean. Tanshinone IIA sodium sulfonate protects against cardiotoxicity induced by doxorubicin in vitro and in vivo. FOOD AND CHEMICAL TOXICOLOGY[J]. 2009, 47(7): 1538-1544, http://dx.doi.org/10.1016/j.fct.2009.03.038.[48] Ma, Chao, Yue, QingXi, Guan, ShuHong, Wu, WanYing, Yang, Min, Jiang, BaoHong, Liu, Xuan, Guo, DeAn. Proteomic analysis of possible target-related proteins of cyclophosphamide in mice thymus. FOOD AND CHEMICAL TOXICOLOGY[J]. 2009, 47(8): 1841-1847, http://dx.doi.org/10.1016/j.fct.2009.04.041.[49] Yao, Yan, Liu, AiHua, Wu, WanYing, Guan, ShuHong, Jiang, BaoHong, Yang, Min, Bi, KaiShun, Liu, Xuan, Guo, DeAn. Possible target-related proteins of salvianolic acids in rat platelets. PHYTOCHEMISTRY LETTERS[J]. 2008, 1(3): 135-138, http://dx.doi.org/10.1016/j.phytol.2008.07.003.[50] 吴婉莹, 杨洲, 侯晋军, 果德安. 总丹参酮不同纯化工艺的比较. 中草药[J]. 2008, 39(12): 1815-, http://lib.cqvip.com/Qikan/Article/Detail?id=28975220.[51] 吴婉莹, 果德安. 丹参中总酚酸的大孔吸附树脂分离纯化与富集. 中草药[J]. 2008, 39(6): 862-864, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=3357846&detailType=1.[52] Yao, Yan, Wu, WanYing, Liu, AiHua, Deng, ShaoSheng, Bi, KaiShun, Liu, Xuan, Guo, DeAn. Interaction of salvianolic acids and notoginsengnosides in inhibition of ADP-induced platelet aggregation. AMERICAN JOURNAL OF CHINESE MEDICINE[J]. 2008, 36(2): 313-328, http://ir.simm.ac.cn/handle/153631/1395.[53] Jiang, Baohong, Zhang, Lin, Li, Ming, Wu, Wanying, Yang, Min, Wang, Junchen, Guo, Dean. Salvianolic acids prevent acute doxorubicin cardiotoxicity in mice through suppression of oxidative stress. FOOD AND CHEMICAL TOXICOLOGY[J]. 2008, 46(5): 1510-1515, http://dx.doi.org/10.1016/j.fct.2007.12.020.[54] Yao, Yan, Wu, WanYing, Guan, ShuHong, Jiang, BaoHong, Yang, Min, Chen, XiaoHui, Bi, KaiShun, Liu, Xuan, Guo, DeAn. Proteomic analysis of differential protein expression in rat platelets treated with notoginsengnosides. PHYTOMEDICINE[J]. 2008, 15(10): 800-807, http://dx.doi.org/10.1016/j.phymed.2008.06.013.[55] Xu, Man, Fu, Gang, Qiao, Xue, Wu, WanYing, Guo, Hui, Liu, AiHua, Sun, JiangHao, Guo, DeAn. HPLC method for comparative in rat after oral administration study on tissue distribution of salvianolic acid B and phenolic acids from Salvia miltiorrhiza. BIOMEDICAL CHROMATOGRAPHY[J]. 2007, 21(10): 1052-1063, https://www.webofscience.com/wos/woscc/full-record/WOS:000249846400008.[56] Wan-ying Wu. Induction of apoptosis and G2/Mcell cycle arrest by oridoninin human gastric cancer BGC-823 cells. Journal of Chinese Pharmaceutical Sciences. 2007, [57] Wu, WanYing, Guo, HongZhu, Qu, GuiQin, Han, Jian, Guo, DeAn. Mechanisms of pseudolaric acid B-induced apoptosis in Bel-7402 cell lines. AMERICAN JOURNAL OF CHINESE MEDICINE[J]. 2006, 34(5): 887-899, https://www.webofscience.com/wos/woscc/full-record/WOS:000241972000014.[58] Zhang, W, Ye, M, Qu, GQ, Wu, WY, Chen, YJ, Guo, DA. Microbial hydroxylation of cinobufagin by Mucor spinosus. 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