基本信息
赵同标  男  博导  中国科学院动物研究所
电子邮件: tbzhao@ioz.ac.cn
通信地址: 北京市朝阳区北辰西路1号院5号
邮政编码: 100101

研究领域

研究组围绕干细胞基础与临床转化研究中的免疫学问题,重点聚焦于以下研究方向:

(1)干细胞临床转化的免疫学基础

(2)干细胞命运决定的物质能量代谢基础

(3)多能干细胞的定向分化


招生信息

   
招生专业
071008-发育生物学
071009-细胞生物学
071010-生物化学与分子生物学
招生方向
干细胞, 再生医学
免疫学
定向分化

教育背景

2000-09--2004-07   中国科学院西北高原生物研究所   博士

工作经历

   
工作简历
2012-02~现在, 中国科学院动物研究所, 研究员
2010-12~2012-01,加州大学圣地亚哥分校, Assistant Specialist III
2007-09~2010-11,加州大学圣地亚哥分校, 博士后
2006-11~2007-08,美国威斯康星血液中心血液研究所, 博士后
2006-09~2006-10,中国科学院生物物理研究所, 副研究员
2004-09~2006-08,中国科学院生物物理研究所, 博后
社会兼职
2017-11-01-今,科学通报, 编委
2017-08-01-今,国际标准化组织/生物技术标准化委员会(ISO/TC276), 委员
2017-07-01-今,Animal Models and Experimental Medicine, 编委
2017-01-01-今,中国细胞生物学会干细胞分会标准工作小组, 组长
2016-09-01-今,中国细胞生物学学会干细胞生物学分会, 委员
2015-01-01-今,中华医学会组织修复与再生分会青年委员会, 理事
2013-12-01-今,发育医学电子杂志, 编委

教授课程

生殖免疫学
组织工程学
医学免疫学
干细胞生物学
干细胞研究进展系列讲座
生殖生物学

专利与奖励

   
奖励信息
(1) 斯丹赛社会公益奖, 其他, 2017
(2) 青年科学之星银奖, 院级, 2013
(3) 中国科学院院长优秀奖, , 部委级, 2003

出版信息

   
发表论文
[1] Yu, Miao, Lei, Wei, Cao, Jiani, Wang, Lei, Ma, Aijin, Zhao, ZhenAo, Yang, HuangTian, Shen, Zhenya, Lan, Feng, Cao, Feng, Liang, Ping, Pei, Xuetao, Xiang, Andy Peng, Yu, Junying, Zhang, Yu, Zhang, Yong, Li, Qiyuan, Zhou, Jiaxi, Wei, Jun, Peng, Yaojin, Zhu, Huanxin, Liang, Lingmin, Cao, Nan, Fu, Boqiang, Hao, Jie, Zhao, Tongbiao, Hu, Shijun. Requirements for human cardiomyocytes. CELL PROLIFERATION[J]. 2022, 55(4): http://dx.doi.org/10.1111/cpr.13150.
[2] Kun Liu, Qian Zhao, Hongyan Sun, Lei Liu, Chaoqun Wang, Zheng Li, Youqing Xu, Liang Wang, Lin Zhang, Honghai Zhang, Quan Chen, Tongbiao Zhao. BNIP3 (BCL2 interacting protein 3) regulates pluripotency by modulating mitochondrial homeostasis via mitophagy. Cell Death and Disease[J]. 2022, 13(4): 1-8, https://doaj.org/article/40886576fb1843fca6a4a31e9bdfd344.
[3] Chen, Xiaoyong, Huang, Jing, Wu, Jun, Hao, Jie, Fu, Boqiang, Wang, Ying, Zhou, Bo, Na, Tao, Wei, Jun, Zhang, Yong, Li, Qiyuan, Hu, Shijun, Zhou, Jiaxi, Yu, Junying, Wu, Zhaohui, Zhu, Huanxin, Cao, Jiani, Wang, Lei, Peng, Yaojin, Liang, Lingmin, Ma, Aijin, Zhang, Yu, Zhao, Tongbiao, Xiang, Andy Peng. Human mesenchymal stem cells. CELL PROLIFERATION[J]. 2022, 55(4): http://dx.doi.org/10.1111/cpr.13141.
[4] Kun Liu, Xing Li, Zheng Li, Jiani Cao, Xiaoyan Li, Youqing Xu, Lei Liu, Tongbiao Zhao. Evaluating mitophagy in embryonic stem cells by using fluorescence-based imaging. Frontiers in Cell and Developmental Biology[J]. 2022, 10: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520453/.
[5] Wang, Lei, Cao, Jiani, Peng, Yaojin, Fu, Boqiang, Jin, Zibing, Hu, Yuntao, Wu, Wei, Xiang, Andy Peng, Hu, Shijun, Yu, Junying, Zhang, Yu, Wei, Jun, Zhang, Yong, Li, Qiyuan, Zhou, Jiaxi, Zhai, Peijun, Zhu, Huanxin, Liang, Lingmin, Ma, Aijin, Stacey, Glyn, Zhao, Tongbiao, Hao, Jie. Human retinal pigment epithelial cells. CELL PROLIFERATION[J]. 2022, 55(4): http://dx.doi.org/10.1111/cpr.13153.
[6] Peng, Zhaoliang, Wu, Jiaying, Hu, Shijun, Ma, Aijin, Wang, Lei, Cao, Nan, Zhang, Yu, Li, Qiyuan, Yu, Junying, Meng, Shufang, Na, Tao, Shi, Xiaolei, Li, Mei, Liu, Huadong, Qian, Linguang, Tian, E, Lin, Feng, Cao, Jiani, Peng, Yaojin, Zhu, Huanxin, Liang, Lingmin, Hao, Jie, Zhao, Tongbiao, Cheng, Xin, Pan, Guoyu. Requirments for primary human hepatocyte. CELL PROLIFERATION[J]. 2022, 55(4): http://dx.doi.org/10.1111/cpr.13147.
[7] Cao, Jiani, Stacey, Glyn, ShyhChang, Ng, Zhao, Tongbiao. Developing standards to support cell technology applications. CELL PROLIFERATIONnull. 2022, 55(4): http://dx.doi.org/10.1111/cpr.13210.
[8] ZHAOTong-Biao. BNIP3-dependent mitophagy safeguards ESC genomic integrity via preventing oxidative stress-induced DNA damage and protecting homologous recombination. Cell Death and Disease[J]. 2022, [9] Jin, Liyuan, Cao, Lei, Zhu, Yingjie, Cao, Jiani, Li, Xiaoyan, Zhou, Jianxia, Liu, Bing, Zhao, Tongbiao. Enhance anti-lung tumor efficacy of chimeric antigen receptor-T cells by ectopic expression of C?C motif chemokine receptor 6. SCIENCE BULLETIN[J]. 2021, 66(8): 803-812, http://dx.doi.org/10.1016/j.scib.2020.12.027.
[10] Wang, Chaoqun, Liu, Kun, Cao, Jiani, Wang, Liang, Zhao, Qian, Li, Zheng, Zhang, Honghai, Chen, Quan, Zhao, Tongbiao. PINK1-mediated mitophagy maintains pluripotency through optineurin. CELL PROLIFERATION[J]. 2021, 54(5): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8088463/.
[11] Nan, Xue, Zhang, Bowen, Hao, Jie, Yue, Wen, Fu, Boqiang, Qu, Mingyi, Zhang, Yu, Wang, Haiyang, Fang, Fang, Wei, Jun, Li, Qiyuan, Hu, Shijun, Yu, Junying, Gao, Yingdai, Liu, Qifa, Cao, Jiani, Wang, Lei, Peng, Yaojin, Zhu, Huanxin, Liang, Lingmin, Ma, Aijin, Zhou, Jiaxi, Zhao, Tongbiao, Pei, Xuetao. Requirements for human haematopoietic stem/progenitor cells. CELL PROLIFERATION. 2021, [12] Cao, Jiani, Hao, Jie, Wang, Lei, Tan, Yuanqing, Tian, Yuchang, Li, Shiyu, Ma, Aijin, Fu, Boqiang, Dai, Jianwu, Zhai, Peijun, Xiang, Peng, Zhang, Yong, Cheng, Tao, Peng, Yaojin, Zhou, Qi, Zhao, Tongbiao. Developing standards to support the clinical translation of stem cells. STEM CELLS TRANSLATIONAL MEDICINE[J]. 2021, 10(Suppl 2): S85-S95, http://dx.doi.org/10.1002/sct3.13035.
[13] Hao, Jie, Cao, Jiani, Wang, Lei, Ma, Aijin, Chen, Si, Ding, Jinfeng, Wang, Liu, Fu, Boqiang, Zhang, Yu, Pei, Xuetao, Xiang, Peng, Li, Qiyuan, Zhang, Yong, Zhou, Jiaxi, Hu, Shijun, Yu, Junying, Wei, Jun, Zhu, Huanxin, Stacey, Glyn, Zhao, Tongbiao, Zhou, Qi. Requirements for human embryonic stem cells. CELL PROLIFERATION[J]. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705896/.
[14] Hao, Jie, Ma, Aijin, Wang, Lei, Cao, Jiani, Chen, Si, Wang, Liu, Fu, Boqiang, Zhou, Jiaxi, Pei, Xuetao, Zhang, Yu, Xiang, Peng, Hu, Shijun, Li, Qiyuan, Zhang, Yong, Xia, Yingjie, Zhu, Huanxin, Stacey, Glyn, Zhou, Qi, Zhao, Tongbiao. General requirements for stem cells. CELL PROLIFERATION[J]. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705904/.
[15] Kun Liu, Jiani Cao, Xingxing Shi, Liang Wang, Tongbiao Zhao. Cellular metabolism and homeostasis in pluripotency regulation. Protein & Cell[J]. 2020, 11(9): 630-640, VIP_JournalArticle.
[16] 王亮, 叶雄俊, 赵同标. The physiological roles of autophagy in the mammalian life cycle. Biological Reviews[J]. 2019, 94(2): 503-516, https://www.webofscience.com/wos/woscc/full-record/WOS:000461070800008.
[17] 田宇昌, 李世煜, 赵同标. 细胞氧气感知与适应机制. 科学通报[J]. 2019, 64(36): 1-7, http://lib.cqvip.com/Qikan/Article/Detail?id=7101004939.
[18] Haifeng Gu, Xingxing Shi, Chao Liu, Chaoqun Wang, Ning Sui, Yu Zhao, Jiaqi Gong, Fuping Wang, Hong Zhang, Wei Li, Tongbiao Zhao. USP8 maintains embryonic stem cell stemness via deubiquitination of EPG5. Nature Communications[J]. 2019, 10(1): 1-9, https://doaj.org/article/c74f5c2d2f504fb9a202f4f7c7b79dfe.
[19] Liu, Kun, Wang, Liang, Zhao, Tongbiao, Qin, ZH. Autophagy in Normal Stem Cells and Specialized Cells. AUTOPHAGY: BIOLOGY AND DISEASES: BASIC SCIENCE[J]. 2019, 1206: 489-508, [20] Zhou, Jianxia, Jin, Liyuan, Wang, Fuping, Zhang, Yuan, Liu, Bing, Zhao, Tongbiao. Chimeric antigen receptor T (CAR-T) cells expanded with IL-7/IL-15 mediate superior antitumor effects. PROTEIN & CELL[J]. 2019, 10(10): 764-769, http://lib.cqvip.com/Qikan/Article/Detail?id=7100271928.
[21] 姚玉琛, 朱少华, 曹佳妮, 张琳, 杨月伟, 赵同标. 强力霉素诱导型Cas9基因编辑小鼠胚胎干细胞系的构建. 发育医学电子杂志[J]. 2018, 6(3): 160-165, http://lib.cqvip.com/Qikan/Article/Detail?id=675956596.
[22] Gong, Jiaqi, Gu, Haifeng, Zhao, Lin, Wang, Liang, Liu, Pinglei, Wang, Fuping, Xu, Haoyu, Zhao, Tongbiao. Phosphorylation of ULK1 by AMPK is essential for mouse embryonic stem cell self-renewal and pluripotency. CELL DEATH & DISEASE[J]. 2018, 9(2): https://doaj.org/article/a833906f9f8e4e76b512b5adf9abeb72.
[23] Yu, Yang, Wang, Xiaoxiao, Zhang, Xiaoxin, Zhai, Yanhua, Lu, Xukun, Ma, Haixia, Zhu, Kai, Zhao, Tongbiao, Jiao, Jianwei, Zhao, ZhenAo, Li, Lei. ERK inhibition promotes neuroectodermal precursor commitment by blocking self-renewal and primitive streak formation of the epiblast. STEM CELL RESEARCH & THERAPY[J]. 2018, 9(1): https://doaj.org/article/764aa9c206ec4311b97d8dcf2be4e4de.
[24] 王福平, 张锋, 赵同标. 人尿源干细胞的分离与鉴定. 生物技术通报[J]. 2018, 34(8): 190-198, http://lib.cqvip.com/Qikan/Article/Detail?id=676479060.
[25] 王亮, 赵同标. “克隆猴”的前世今生. 科学通报[J]. 2018, 63(18): 1758-1763, http://lib.cqvip.com/Qikan/Article/Detail?id=675632893.
[26] Liang Wang, Xiongjun Ye, Tongbiao Zhao. The physiological roles of autophagy in the mammalian life cycle. Biological Reviews of the Cambridge Philosophical Society. 2018, 94(2): 503-516, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7379196/.
[27] Sun, Hongyan, Cao, Jiani, Zhao, Lin, Zhu, Shaohua, Chen, Shenghui, Li, Yaqiong, Zhao, Bin, Zhao, Tongbiao. PIM2 regulates stemness through phosphorylation of 4E-BP1. SCIENCE BULLETIN[J]. 2017, 62(10): 679-685, http://dx.doi.org/10.1016/j.scib.2017.04.018.
[28] 张娟, 陈双全, DongMing Zhang, 史子啸, 李红, 赵同标, 胡宝洋, 周琪, 焦建伟. TET3介导的DNA去甲基化诱导成纤维细胞转分化为功能神经元. 科学新闻[J]. 2017, 164-164, http://lib.cqvip.com/Qikan/Article/Detail?id=672078148.
[29] 王亮, 赵同标. CRISPR/Cas9的原理及其在疾病治疗中的研究进展. 发育医学电子杂志[J]. 2017, 5(1): 35-44, http://lib.cqvip.com/Qikan/Article/Detail?id=672989358.
[30] Liu, Pinglei, Liu, Kun, Gu, Haifeng, Wang, Weixu, Gong, Jiaqi, Zhu, Yingjie, Zhao, Qian, Cao, Jiani, Han, Chunseng, Gao, Fei, Chen, Quan, Li, Wei, Jiao, Jianwei, Hu, Baoyang, Zhou, Qi, Zhao, Tongbiao. High autophagic flux guards ESC identity through coordinating autophagy machinery gene program by FOXO1. CELL DEATH AND DIFFERENTIATION[J]. 2017, 24(10): 1672-1680, https://www.webofscience.com/wos/woscc/full-record/WOS:000410166300002.
[31] Zhu, Shaohua, Cao, Jiani, Sun, Hongyan, Liu, Kun, Li, Yaqiong, Zhao, Tongbiao. p18 inhibits reprogramming through inactivation of Cdk4/6. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000380650500001.
[32] Cao, Jiani, Zhao, Tongbiao. Single-cell sequencing delivers hematopoietic stem cell specification. SCIENCE BULLETIN. 2016, 61(18): 1419-1421, http://dx.doi.org/10.1007/s11434-016-1163-2.
[33] Zhang, Chao, Cao, Jiani, Li, Xiaoyan, Xu, Haoyu, Wang, Weixu, Wang, Libin, Zhao, Xiaoyang, Li, Wei, Jiao, Jianwei, Hu, Baoyang, Zhou, Qi, Zhao, Tongbiao. Treatment of multiple sclerosis by transplantation of neural stem cells derived from induced pluripotent stem cells. SCIENCE CHINA-LIFE SCIENCES[J]. 2016, 59(9): 950-957, https://www.webofscience.com/wos/woscc/full-record/WOS:000382944400010.
[34] Zhang, H, Cheng, H, Wang, Y, Zheng, Y, Liu, Y, Liu, K, Xu, J, Hao, S, Yuan, W, Zhao, T, Cheng, T. Reprogramming of Notch1-induced acute lymphoblastic leukemia cells into pluripotent stem cells in mice. BLOOD CANCER JOURNAL. 2016, 6(7): e444-, https://www.webofscience.com/wos/woscc/full-record/WOS:000380851900005.
[35] Zhang, Juan, Chen, Shuangquan, Zhang, Dongming, Shi, Zixiao, Li, Hong, Zhao, Tongbiao, Hu, Baoyang, Zhou, Qi, Jiao, Jianwei. Tet3-Mediated DNA Demethylation Contributes to the Direct Conversion of Fibroblast to Functional Neuron. CELL REPORTS[J]. 2016, 17(9): 2326-2339, http://dx.doi.org/10.1016/j.celrep.2016.10.081.
[36] Liu, Kun, Zhao, Qian, Liu, Pinglei, Cao, Jiani, Gong, Jiaqi, Wang, Chaoqun, Wang, Weixu, Li, Xiaoyan, Sun, Hongyan, Zhang, Chao, Li, Yufei, Jiang, Minggui, Zhu, Shaohua, Sun, Qingyuan, Jiao, Jianwei, Hu, Baoyang, Zhao, Xiaoyang, Li, Wei, Chen, Quan, Zhou, Qi, Zhao, Tongbiao. ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance. AUTOPHAGY[J]. 2016, 12(11): 2000-2008, https://www.webofscience.com/wos/woscc/full-record/WOS:000387665000004.
[37] Deng, Zhili, Lei, Xiaohua, Zhang, Xudong, Zhang, Huishan, Liu, Shuang, Chen, Qi, Hu, Huimin, Wang, Xinyue, Ning, Lina, Cao, Yujing, Zhao, Tongbiao, Zhou, Jiaxi, Chen, Ting, Duan, Enkui. mTOR signaling promotes stem cell activation via counterbalancing BMP-mediated suppression during hair regeneration. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2015, 7(1): 62-72, https://www.webofscience.com/wos/woscc/full-record/WOS:000350228600007.
[38] Zhao, Tongbiao, Zhang, Zhenning, Westenskow, Peter D, Todorova, Dilyana, Hu, Zheng, Lin, Tongxiang, Rong, Zhili, Kim, Jinchul, He, Jingjin, Wang, Meiyan, Clegg, Dennis O, Yang, Yongguang, Zhang, Kun, Friedlander, Martin, Xu, Yang. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. CELL STEM CELL[J]. 2015, 17(3): 353-359, http://dx.doi.org/10.1016/j.stem.2015.07.021.
[39] Wang, Libin, Cao, Jiani, Wang, Yukai, Lan, Tianshu, Liu, Lei, Wang, Weixu, Jin, Ning, Gong, Jiaqi, Zhang, Chao, Teng, Fei, Yan, Guoliang, Li, Chun, Li, Jiali, Wan, Haifeng, Hu, Baoyang, Li, Wei, Zhao, Xiaoyang, Qi, Zhongquan, Zhao, Tongbiao, Zhou, Qi. Immunogenicity and functional evaluation of iPSC-derived organs for transplantation. CELL DISCOVERY[J]. 2015, 1: 15015-, https://www.webofscience.com/wos/woscc/full-record/WOS:000414776800015.
[40] 李晓燕, 胡正, 赵同标. 人源化小鼠在人造血免疫系统研究中的应用. 发育医学电子杂志[J]. 2014, http://lib.cqvip.com/Qikan/Article/Detail?id=1005328497.
[41] Liu, K, Song, Y, Yu, H, Zhao, T. Understanding the roadmaps to induced pluripotency. CELL DEATH & DISEASE[J]. 2014, 5: https://www.webofscience.com/wos/woscc/full-record/WOS:000337229300032.
[42] 李嘉宁, 刘鹏霞. 家畜诱导性多能干细胞研究进展. 生物技术通报[J]. 2014, 28-33, [43] 宋卫华, 刘坤, 赵同标. 诱导多能干细胞研究进展. 生物技术通报[J]. 2014, 1-7, [44] Cao, Jiani, Li, Xiaoyan, Lu, Xiao, Zhang, Chao, Yu, Honghao, Zhao, Tongbiao. Cells derived from iPSC can be immunogenic - Yes or No?. PROTEIN & CELL. 2014, 5(1): 1-3, https://www.webofscience.com/wos/woscc/full-record/WOS:000332461300001.
[45] Xiao Lu, Zhao Tongbiao. Clinical Therapy Using iPSCs: Hopes and Challenges. Genomics, Proteomics & Bioinformatics[J]. 2013, 11(5): 294-298, http://lib.cqvip.com/Qikan/Article/Detail?id=47712343.
[46] Xiao Lu Tongbiao Zhao. Clinical Therapy Using iPSCs: Hopes and Challenges. 基因组蛋白质组与生物信息学报:英文版[J]. 2013, 11(5): 294-298, http://lib.cqvip.com/Qikan/Article/Detail?id=47712343.
[47] Zhao, Tongbiao, Zhang, ZhenNing, Rong, Zhili, Xu, Yang. Immunogenicity of induced pluripotent stem cells. NATURE[J]. 2011, 474(7350): 212-U251, https://www.webofscience.com/wos/woscc/full-record/WOS:000291397800050.
[48] Zhao, Tongbiao, Xu, Yang. p53 and stem cells: new developments and new concerns. TRENDS IN CELL BIOLOGYnull. 2010, 20(3): 170-175, http://dx.doi.org/10.1016/j.tcb.2009.12.004.
[49] MorettoZita, Matteo, Jin, Hua, Shen, Zhouxin, Zhao, Tongbiao, Briggs, Steven P, Xu, Yang. Phosphorylation stabilizes Nanog by promoting its interaction with Pin1. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2010, 107(30): 13312-13317, https://www.webofscience.com/wos/woscc/full-record/WOS:000280602800025.
[50] Guo, Yuming, Chen, Jun, Zhao, Tongbiao, Fan, Zusen. Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity. MOLECULAR IMMUNOLOGY[J]. 2008, 45(8): 2225-2235, http://dx.doi.org/10.1016/j.molimm.2007.11.020.
[51] Zhao, T, Zhang, H, Guo, Y, Zhang, Q, Hua, G, Lu, H, Hou, Q, Liu, H, Fan, Z. Granzyme K cleaves the nucleosome assembly protein SET to induce single-stranded DNA nicks of target cells. CELL DEATH AND DIFFERENTIATION[J]. 2007, 14(3): 489-499, https://www.webofscience.com/wos/woscc/full-record/WOS:000244275400012.
[52] 赵同标. Granzyme K directly processes Bid to release of cytochrome c and endonuclease G leading to mitochondrial - dependent cell death. J Biol Chem. 2007, [53] 赵同标. Granzyme H induces rapid apoptosis of target cells characterized by DNA fragmentation and Bid dependent mitochondrial damage. Mol Immunol. 2007, [54] 赵同标. Granzyme M directly cleaves ICAD to unleash caspase-activated DNase leading to DNA fragmentation. J Immunol. 2006, [55] 赵同标. Tissue Specific Expression of Plateau Pikas(Ochotona curzoniae)HIF-1αmRNA Under Normal Oxygen. Zoological Research. 2004, [56] 赵同标. Cloning of Hypoxia-Inducible Factor 1α (HIF-1α) cDNA from high hypoxia tolerance animal - Plateau Pika. 2004, [57] 赵同标. Rapid Cloning Homologous cDNA from Different Species. Biotechnology Information. 2003, [58] 赵同标. A Preliminary Study of Plateau Pika (Ochotona curzoniae) Hypoxia-Induced Factor-1α (HIF-1α). Acta Theriologica sinica. 2003, [59] Zhao, TB, Chang, ZJ, Zhao, XQ. A new oxygen-binding globin: Neuroglobin. PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS[J]. 2003, 30(6): 844-846, http://210.75.249.4/handle/363003/6943.

科研活动

   
科研项目
( 1 ) 多能干细胞临床应用的免疫学基础, 主持, 部委级, 2013-01--2015-12
( 2 ) 诱导多能干细胞免疫原性产生的机制研究, 主持, 国家级, 2013-03--2016-12
( 3 ) 青年****, 主持, 研究所(学校), 2013-01--2015-12
( 4 ) 免疫反应在神经系统自身免疫疾病及其神经干细胞治疗中的作用机制, 主持, 国家级, 2016-01--2019-12
( 5 ) 异种,异源细胞和器官的灵长类动物移植探索及其免疫学基础, 参与, 国家级, 2014-01--2016-12
( 6 ) 干细胞与再生医学, 参与, 国家级, 2017-01--2022-12
( 7 ) 临床级细胞资源与获得, 参与, 部委级, 2017-01--2018-12
( 8 ) 深入研究小鼠各种多能干细胞分化过程中免疫原性变化规律及其分子机制, 主持, 国家级, 2013-01--2017-12
( 9 ) 人多能干细胞向功能T细胞定向分化的机制研究, 主持, 国家级, 2018-01--2022-12
( 10 ) 人/猪造血系统胚胎嵌合体的建立, 主持, 部委级, 2017-12--2022-11
参与会议
(1)Metabolic regulation of pluripotency   第八届中国医药生物技术论坛   2018-10-18
(2)Autophagy regulation of pluripotency   第一届 中国自噬大会   2018-09-03
(3)干细胞代谢调控   第六届长白山论坛   2018-07-28
(4)Mitophagy regulation of pluripotency   中国细胞生物学学会2018年全国学术大会   2018-04-13
(5)干细胞标准化与产业发展   2018中国整合生物样本学大会暨BBCMBA十周年庆典   2018-03-29
(6)Autophagy regulation of pluripotency   第九届“秦鹏春教育基金”生命科学论坛   2017-12-08
(7)General requirements for sterility tests of animal cells   国际标准化组织/生物技术标准化技术委员会(ISO/TC276)工作组会议   2017-11-30
(8)干细胞通用要求   《干细胞通用要求》新闻发布会   2017-11-22
(9)干细胞与免疫学   中国干细胞第七届年会   2017-07-06
(10)ATG3-dependent autophagy mediates mitochondrial homeostasis in pluripotency acquirement and maintenance   2016-04-18
(11)Immunogenicity of iPSCs   中国免疫学会第十届全国免疫学学术大会   2015-12-08
(12)Immunogenicity of cells derived from human Induced Pluripotent Stem cells   中国干细胞第五届年会   2015-11-13
(13)iPS细胞生成的神经干细胞移植对多发性硬化症的治疗   第八届北京干细胞论坛   2015-07-13
(14)多能干细胞临床开发的免疫学挑战   第七届北京干细胞论坛   赵同标   2014-05-10
(15)Immunogenicity of induced pluripotent stem cells   2012-04-19

指导学生

已指导学生

王伟绪  硕士研究生  071008-发育生物学  

张超  博士研究生  071008-发育生物学  

宫佳琦  硕士研究生  071008-发育生物学  

刘平磊  博士研究生  071008-发育生物学  

孙红艳  博士研究生  071008-发育生物学  

刘坤  博士研究生  071008-发育生物学  

徐昊宇  硕士研究生  071008-发育生物学  

现指导学生

靳利远  博士研究生  071008-发育生物学  

周建霞  博士研究生  071008-发育生物学  

张媛  硕士研究生  0710J6-再生医学  

朱颖婕  硕士研究生  071008-发育生物学  

王亮  博士研究生  0710J6-再生医学  

赵瑜  硕士研究生  0710J6-再生医学  

徐昊宇  博士研究生  0710J6-再生医学  

李兴  博士研究生  0710J6-再生医学