基本信息
曲广波  男  博导  中国科学院生态环境研究中心
电子邮件: gbqu@rcees.ac.cn
通信地址: 北京市海淀区双清路18号
邮政编码: 100085

招生信息

   
招生专业
0703J1-纳米科学与技术
0703Z1-化学生物学
100102-免疫学
招生方向
环境污染与健康
新型污染物分析
污染物与生物效应

教育背景

2008-09--2011-06   中国科学院生态环境研究中心   理学博士
2000-09--2004-07   黑龙江大学生命科学学院   理学学士

工作经历

   
工作简历
2015-03~2015-05,美国迈阿密大学米勒医学院, 访问学者,博士后
2015-01~现在, 中国科学院生态环境研究中心, 副研究员
2014-01~2015-02,美国印第安纳大学医学院, 访问学者,博士后
2011-07~2014-12,中国科学院生态环境研究中心, 助理研究院
2010-07~2011-02,香港科技大学化学系, 研究助理
2005-09~2008-07,山东大学药学院, 医学硕士

教授课程

纳米毒理学

出版信息

   
发表论文
(1) High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly- and per-fluoroalkyl substances (PFASs) in environmental and human samples, Trends in Analytical Chemistry, 2019-02, 通讯作者
(2) Improved Biocompatibility of Black Phosphorus Nanosheets by Chemical Modification, Angewandte Chemie International Edition, 2017, 第 1 作者
(3) Determining the Cytotoxicity of Rare Earth Element Nanoparticles in Macrophages and the Involvement of Membrane Damage, Environmental Scicence & Technology, 2017, 通讯作者
(4) Structure-Dependent Hematological Effects of Per- and Polyfluoroalkyl Substances on Activation of Plasma Kallikrein-Kinin System Cascade, Environmental Science & Technology, 2017, 第 3 作者
(5) Distinct toxicological characteristics and mechanisms of Hg(2+) and MeHg in Tetrahymena under low concentration exposure, Aquatic Toxicology, 2017, 第 2 作者
(6) Identification of Emerging Brominated Chemicals as the Transformation Products of Tetrabromobisphenol A (TBBPA) Derivatives in Soil, Environmental Science & Technology, 2017, 通讯作者
(7) Sensitive immunoassay for simultaneous determination of tetrabromobisphenol A bis(2-hydroxyethyl) ether and tetrabromobisphenol A mono(hydroxyethyl) ether: An effective and reliable strategy to estimate the typical tetrabromobisphenol A derivative and byproduct in aquatic environments, Environmental Pollution, 2017, 通讯作者
(8) A crucial role of heme-regulated eIF2 alpha kinase in maintaining cytoskeletal meshwork under an oxygen deficient condition, Science Bulletin, 2017, 第 1 作者
(9) Recent advances in the analysis of TBBPA/TBBPS, TBBPA/TBBPS derivatives and their transformation products, Trends in Analytical Chemistry, 2016, 第 1 作者
(10) Graphene enhances cellular proliferation through activating EGFR, Journal of Agricultural and Food Chemistry, 2016, 第 6 作者
(11) The potential neurotoxicity of emerging tetrabromobisphenol A derivatives based on rat pheochromocytoma cells, Chemosphere, 2016, 第 5 作者
(12) Carbon nanotubes stimulate synovial inflammation through inducing systemic pro-inflammatory cytokines, Nanoscale, 2016, 第 3 作者
(13) Tetrabromobisphenol-A/S and Nine Novel Analogs in Biological Samples from the Chinese Bohai Sea: Implications for Trophic Transfer, Environmental science & technology, 2016, 第 2 作者
(14) Exposure, Tissue Biodistribution, and Biotransformation of Nanosilver, NanoImpact, 2016, 第 3 作者
(15) Silver ion post-column derivatization electrospray ionization mass spectrometry for determination of tetrabromobisphenol A derivatives in water samples, RSC Advances, 2015, 第 3 作者
(16) Identification of two novel brominated contaminants in water samples by ultra-high performance liquid chromatography-Orbitrap Fusion Tribrid mass spectrometer, Journal of Chromatography A, 2015, 第 2 作者
(17) Reactive extractive electrospray ionization tandem mass spectrometry for sensitive detection of tetrabromobisphenol A derivatives, Analytica chimica acta, 2014, 第 4 作者
(18) Graphene Oxide Induces Toll-like Receptor 4 (TLR4)-Dependent Necrosis in Macrophages, ACS Nano, 2013, 第 1 作者
(19) Identification of Tetrabromobisphenol A Allyl Ether and Tetrabromobisphenol A 2,3-Dibromopropyl Ether in the Ambient Environment near a Manufacturing Site and in Mollusks at a Coastal Region, Environmental Science & Technology, 2013, 第 1 作者
(20) Evaluation of the biological fate and the transport through biological barriers of nanosilver in mice, Current pharmaceutical design, 2013, 第 2 作者
(21) The capability of quantum dots in crossing the placental barrier and the potential influence on erythrocytes, Journal of nanoscience and nanotechnology, 2013, 第 3 作者
(22) Quantum dots (QDs) restrain human cervical carcinoma HeLa cell proliferation through inhibition of the ROCK-c-Myc signaling, Integrative Biology, 2013, 第 1 作者
(23) Downregulation of ubiquitin E3 ligase TNF receptor-associated factor 7 leads to stabilization of p53 in breast cancer, Oncology reports, 2013, 第 4 作者
(24) Characterization of the interaction between cadmium and chlorpyrifos with integrative techniques in incurring synergistic hepatoxicity, PloS one, 2013, 第 2 作者
(25) Simultaneous determination of five estrogens and four androgens in water samples by online solid-phase extraction coupled with high-performance liquid chromatography–tandem mass spectrometry, Journal of chromatography A, 2013, 第 3 作者
(26) A protective role of heme-regulated eIF2α kinase in cadmium-induced toxicity in erythroid cells, Food and chemical toxicology, 2013, 第 4 作者
(27) Influence of e-waste dismantling and its regulations: temporal trend, spatial distribution of heavy metals in rice grains, and its potential health risk, Environmental science & technology, 2013, 第 4 作者
(28) The ex vivo and in vivo biological performances of graphene oxide and the impact of surfactant on graphene oxide's biocompatibility, Journal of Environmental Sciences, 2013, 第 1 作者
(29) Cytotoxicity of quantum dots and graphene oxide to erythroid cells and macrophages, Nanoscale research letters, 2013, 第 1 作者
(30) Silver nanoparticles induced RNA polymerase-silver binding and RNA transcription inhibition in erythroid progenitor cells, ACS nano, 2013, 第 4 作者
(31) Quantum dots impair macrophagic morphology and the ability of phagocytosis by inhibiting the Rho-associated kinase signaling, Nanoscale, 2012, 第 1 作者
(32) Sample preparation method for the speciation of polybrominated diphenyl ethers and their methoxylated and hydroxylated analogues in diverse environmental matrices, Talanta, 2012, 第 4 作者
(33) Temporal trends (2005–2009) of PCDD/Fs, PCBs, PBDEs in rice hulls from an e-waste dismantling area after stricter environmental regulations, Chemosphere, 2012, 第 4 作者
(34) Identification of Tetrabromobisphenol A Diallyl Ether as an Emerging Neurotoxicant in Environmental Samples by Bioassay-Directed Fractionation and HPLC-APCI-MS/MS, Environmental Science & Technology, 2011, 第 1 作者
(35) Detection of tris-(2, 3-dibromopropyl) isocyanurate as a neuronal toxicant in environmental samples using neuronal toxicity-directed analysis, Science China Chemistry, 2011, 第 1 作者
(36) The effect of multiwalled carbon nanotube agglomeration on their accumulation in and damage to organs in mice, Carbon, 2009, 第 1 作者

科研活动

   
科研项目
( 1 ) 稀土氧化物纳米材料对DNA甲基化和羟 甲基化的调控机理及其毒性研究, 主持, 国家级, 2016-01--2019-12
( 2 ) 纳米银对巨噬细胞毒性的机理研究, 主持, 国家级, 2013-01--2015-12
( 3 ) 典型污染物的环境暴露与健康危害机制, 参与, 部委级, 2014-07--2019-07
( 4 ) 典型人工纳米材料的水环境过程、生物效应及其调控研究, 参与, 国家级, 2014-01--2019-12
( 5 ) 化学环境污染与健康, 主持, 国家级, 2018-01--2020-12
参与会议
(1)Neural toxicity assay-directed analysis: application in novel pollutant identification   2012-09-23

指导学生

现指导学生

李平  硕士研究生  071300-生态学  

王易  硕士研究生  085229-环境工程