基本信息
赵凯 男 博导 中国科学院西北高原生物研究所
电子邮件: zhaokai@nwipb.cas.cn
通信地址: 青海省西宁市新宁路23号
邮政编码: 810008
电子邮件: zhaokai@nwipb.cas.cn
通信地址: 青海省西宁市新宁路23号
邮政编码: 810008
招生信息
招生专业
071002-动物学071300-生态学090501-动物遗传育种与繁殖
招生方向
适应基因组学分子生态和进化基因组学动物遗传育种
教育背景
2002-09--2005-07 西北农林科技大学、中国科学院水生生物研究所 博士1996-09--1999-07 西北农业大学 硕士1986-09--1990-07 青海畜牧兽医学院读大学 学士
工作经历
工作简历
2010-01~现在, 中国科学院西北高原生物研究所, 研究员2007-01~2009-12,中国科学院西北高原生物研究所, 博士后2005-08~2007-12,青海大学, 教授2002-09~2005-07,西北农林科技大学、中国科学院水生生物研究所, 博士1999-08~2002-08,青海大学, 副教授1996-09~1999-07,西北农业大学, 硕士1994-04~1996-07,青海畜牧兽医学院, 讲师1990-07~1994-04,青海省畜牧学校, 助教1986-09~1990-07,青海畜牧兽医学院读大学, 学士
社会兼职
2024-04-01-2027-07-31,中国渔业学会原生水生物及水域生态专业委员会, 理事
2024-01-01-2027-12-31,中国动物学会鱼类学分会, 鱼类学会理事
2018-12-31-2023-12-30,青海省动物学会, 副理事长
2024-01-01-2027-12-31,中国动物学会鱼类学分会, 鱼类学会理事
2018-12-31-2023-12-30,青海省动物学会, 副理事长
专利与奖励
奖励信息
(1) 中国科学院兰州分院优秀导师, 一等奖, 院级, 2018
专利成果
( 1 ) 一种呼伦贝尔羊SNP数据库的构建方法, 2022, 第 10 作者, 专利号: CN114023391A( 2 ) 一种用于选育羊多胎品系的试剂盒和方法, 2022, 第 2 作者, 专利号: CN113913540A( 3 ) 一种检测斑马鱼Acsl1a基因突变的方法, 2021, 第 6 作者, 专利号: CN113416787A( 4 ) 地理信息数据处理方法、系统、装置及计算机可读介质, 2021, 第 5 作者, 专利号: CN112650758A( 5 ) 一种青海湖裸鲤胚胎培养液及其制备方法, 2021, 第 6 作者, 专利号: CN112410287A( 6 ) 一种用于实验室养鱼的鱼缸, 2020, 第 4 作者, 专利号: CN211832445U( 7 ) 一种由Crispr/Cas9诱导的鳞片缺失斑马鱼模式及建立方法, 2015, 第 2 作者, 专利号: CN104928321A
出版信息
发表论文
(1) Spatially explicit estimation of freshwater fish stock biomass with limited data: A case study of an endangered endemic fish on the Tibetan Plateau, China, SCIENCE OF THE TOTAL ENVIRONMENT, 2024, 第 15 作者 通讯作者(2) Multiomics Analyses Provide New Insight into Genetic Variation of Reproductive Adaptability in Tibetan Sheep, Molecular Biology and Evolution, 2024, 第 8 作者 通讯作者(3) 青海湖裸鲤FXYD基因家族鉴定、分子进化及表达, Genome-Wide Identification,Molecular Evolution,and Expression of FXYD Gene Family in Tibetan Naked Carp Gymnocypris przewalskii ssp.przewalskii, 水产科学, 2023, 第 7 作者(4) 青海湖裸鲤实时荧光定量PCR内参基因筛选与验证, Selection and Validation of Reference Genes in Gymnocypris przewalskii by Quantitative Real-Time PCR, 水产科学, 2023, 第 6 作者(5) Genetic Polymorphisms of IGF1 and IGF1R Genes and Their Effects on Growth Traits in Hulun Buir Sheep, GENES, 2022, 第 9 作者 通讯作者(6) Physiological, morphological and transcriptomic responses of Tibetan naked carps (Gymnocypris przewalskii) to salinity variations, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS, 2022, 第 6 作者(7) Genome-wide characterization of the Elovl gene family in Gymnocypris przewalskii and their potential roles in adaptation to cold temperature, COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY, 2022, 第 5 作者 通讯作者(8) Identification of Somatostatin Receptor Subtype 1 (SSTR1) Gene Polymorphism and Their Association with Growth Traits in Hulun Buir Sheep, GENES, 2022, 第 9 作者 通讯作者(9) Genome-wide characterization and expression of PPARs gene family in Tibetan highland fish Gymnocypris przewalskii, Fish physiology and biochemistry, 2022, 第 6 作者(10) Phylogenetic relationship and taxonomic status of Gymnocypris eckloni (Schizothoracinae) based on specific locus amplified fragments sequencing, FRONTIERS IN ECOLOGY AND EVOLUTION, 2022, 第 11 作者(11) 澳洲白羊与小尾寒羊杂交F1代背最长肌肉品质与皮下脂肪组织膻味物质分析, Analysis of the Longissimus Dorsi Meat Quality and the Content of Mutton Flavor Substances of F1 Hybrid Sheep between Australian White Sheep and Native Small-Tail Han Sheep, 食品工业科技, 2021, 第 6 作者(12) 青海祁连山区鱼类资源调查, 2021, 第 1 作者 通讯作者(13) Genomic Signature of Shifts in Selection and Alkaline Adaptation in Highland Fish, GENOME BIOLOGY AND EVOLUTION, 2021, 第 4 作者 通讯作者(14) Generation of Ectodysplasin A (eda)-targeted Knockout Zebrafish Via the CRISPR/Cas9 System, KAFKAS UNIVERSITESI VETERINER FAKULTESI DERGISI, 2020, 第 5 作者(15) 本土绵羊品种GH 与IGF-1 基因多态性研究, 基因组学与应用生物学, 2020, 第 1 作者 通讯作者(16) 高寒地区草牧业生产技术体系及产业化模式, 青海畜牧兽医杂志, 2020, 第 5 作者(17) Characterization and development of SSR markers of schizothoracine fish (Cypriniformes: Cyprinidae) based on SLAF-seq Technique, JOURNAL OF APPLIED ICHTHYOLOGY, 2020, 第 5 作者 通讯作者(18) Comparative transcriptome of reproductive axis in Chinese indigenous sheep with different FecB genotypes and prolificacies, ANIMAL REPRODUCTION SCIENCE, 2020, 第 6 作者 通讯作者(19) 黄河流域淡水鱼类多样性和保护, Species diversity and conservation of freshwater fishes in the Yellow River basin, 生物多样性, 2020, 第 6 作者(20) Mitochondrial genome and phylogenetic relationship of Gymnocypris eckloni (Schizothoracinae) in Qaidam river basin, GENOMICS, 2020, 第 6 作者 通讯作者(21) Transcriptome-Wide Patterns of the Genetic and Expression Variations in Two Sympatric Schizothoracine Fishes in a Tibetan Plateau Glacier Lake, GENOME BIOLOGY AND EVOLUTION, 2020, 第 10 作者 通讯作者(22) A new species of Triplophysa(Cypriniformes,Nemacheilidae) from Weihe River in Gansu Province, China, A new species of Triplophysa (Cypriniformes, Nemacheilidae) from Weihe River in Gansu Province, China, ZOOLOGICAL RESEARCH, 2020, 第 8 作者 通讯作者(23) 青海湖裸鲤IL-8的原核表达及诱导条件优化, Construction of Prokaryotic Expression System and Optimization of Expression Conditions of IL-8 in Gymnocypris przewalskii przewalskii, 基因组学与应用生物学, 2020, 第 5 作者(24) 几何形态测量法结合Micro CT扫描对两水系花斑裸鲤的形态分析, MORPHOLOGICAL ANALYSIS USED BY GEOMETRIC MORPHOMETRICS COMBINED WITH MICRO CT AMONGGYMNOCYPRIS ECKLONIIN TWO DRAINAGE (TELEOSTEI: CYPRINIDAE), 水生生物学报, 2020, 第 4 作者(25) Genome-wide identification, phylogeny and expression analysis of G6PC gene family in common carp, Cyprinus carpio, TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, 2020, 第 5 作者 通讯作者(26) Characterization and development of SSR markers of schizothoracine fish (Cypriniformes: Cyprinidae) based pm SLAF-seq Technique, Journal of Applied Ichthyology, 2020, 第 1 作者 通讯作者(27) 青海湖裸鲤和黄河裸裂尻鱼感染多子小瓜虫的病理学比较研究, THE DIFFERENT PATHOLOGY OFGYMNOCYPRIS PRZEWALSKII PRZEWALSKIIANDSCHIZOPYGOPSIS PYLZOVIINFECTED WITHICHTHYOPHTHIRIUS MULTIFILIIS, 水生生物学报, 2019, 第 9 作者(28) Multiple convergent events created a nominal widespread species: Triplophysa stoliczkae (Steindachner, 1866) (Cobitoidea: Nemacheilidae), BMC EVOLUTIONARY BIOLOGY, 2019, 第 6 作者 通讯作者(29) SNaPshot技术检测滩羊双羔群体中与多胎性状相关SNP研究, Research on SNP Associated with Multiparous Trait in Double-lamb of Tan Sheep by SNaPshot Assay, 生物技术通报, 2019, 第 5 作者(30) Convergent evolution misled taxonomy in schizothoracine ���shes (Cypriniformes: Cyprinidae), Molecular phylogenetics and evolution, 2019, 第 1 作者 通讯作者(31) Transcriptomic profiling reveals molecular regulation of seasonal reproduction in Tibetan highland fish, Gymnocypris przewalskii, BMC GENOMICS, 2019, 第 5 作者 通讯作者(32) Convergent evolution misled taxonomy in schizothoracine fishes (Cypriniformes: Cyprinidae), MOLECULAR PHYLOGENETICS AND EVOLUTION, 2019, 第 7 作者 通讯作者(33) Molecular systematics of the Triplophysa robusta (Cobitoidea) complex: Extensive gene flow in a depauperate lineage, MOLECULAR PHYLOGENETICS AND EVOLUTION, 2019, 第 9 作者 通讯作者(34) Adaptive Evolution of the Eda Gene and Scales Loss in Schizothoracine Fishes in Response to Uplift of the Tibetan Plateau., INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 第 10 作者 通讯作者(35) 鲤在低温胁迫下肝胰腺转录组测序分析, Transcriptome Sequencing and Analysis of Hepatopancreas from Carps Under Cold Stress, 生物技术通报, 2018, 第 5 作者(36) 论草牧业的理论体系及其实践, The concept of "Grass-based Livestock Husbandry" and its practice in Hulun Buir, Inner Mongolia, 科学通报, 2018, 第 9 作者(37) Characterization of the complete mitochondrial genome of gymnocypris scleracanthus (teleostei: cyprinidae), CONSERVATION GENETICS RESOURCES, 2018, 第 3 作者 通讯作者(38) Porcine enterocyte protein Btnl5 negatively regulates NF-kappa B pathway by interfering p65 nuclear translocation, GENE, 2018, 第 5 作者 通讯作者(39) Integrated mRNA and microRNA transcriptome analyses reveal regulation of thermal acclimation in Gymnocypris przewalskii: A case study in Tibetan Schizothoracine fish, PLOS ONE, 2017, 第 4 作者 通讯作者(40) The complete mitochondrial genomes of two schizothoracine fishes (Teleostei, Cypriniformes): A novel minisatellite in fish mitochondrial genomes., Journal of Applied Ichthyology, 2017, 第 1 作者 通讯作者(41) Gymnocypris chui Tchang, Yueh & Hwang, 1964 and Gymnocypris scleracanthus Tsao, Wu, Chen & Zhu, 1992 from Lake Langcuo, Qinghai-Tibet Plateau, JOURNAL OF APPLIED ICHTHYOLOGY, 2017, (42) 新疆内陆河土著鱼类资源调查, Survey of native fish resources in inland river system in ***, 甘肃农业大学学报, 2017, 第 5 作者(43) 猪Btnl5基因的克隆、表达分析及对NF-κB信号通路的调控作用, 生物技术通报, 2017, 第 2 作者(44) Comprehensive transcriptomic analysis of Tibetan Schizothoracinae fish Gymnocypris przewalskii reveals how it adapts to a high altitude aquatic, BMC EVOLUTIONARY BIOLOGY, 2017, 第 4 作者 通讯作者(45) Elevational diversity gradients of Tibetan loaches: The relative roles of ecological and evolutionary processes, ECOLOGY AND EVOLUTION, 2017, 第 8 作者 通讯作者(46) Phylogeography of Schizopygopsis stoliczkai (Cyprinidae) in Northwest Tibetan Plateau area, ECOLOGY AND EVOLUTION, 2017, 第 8 作者 通讯作者(47) Transcriptomic profiling of Tibetan highland fish (Gymnocypris przewalskii) in response to the infection of parasite ciliate Ichthyophthirius multifiliis, FISH AND SHELLFISH IMMUNOLOGY, 2017, 第 5 作者(48) Integrated mRNA and microRNA transcriptome analyses reveal regulationin Tibetan Schizothoracine fish, PLOS ONE, 2017, 第 1 作者 通讯作者(49) Comprehensive transcriptomic analysis of Tibetan Schizothoracinae fish Gymnocypris przewalskii reveals how it adapts to a high altitude aquatic life, BMC EVOLUTIONARY BIOLOGY, 2017, 第 4 作者(50) Genomic signature of highland adaptation in fish: a case study in Tibetan Schizothoracinae species, BMC GENOMICS, 2017, 第 3 作者 通讯作者(51) The microRNA repertoire of Tibetan naked carp Gymnocypris przewalskii: A case study in Schizothoracinae fish on the Tibetan Plateau, PLOS ONE, 2017, 第 4 作者 通讯作者(52) 青藏高原东北部边缘高原鳅属鱼类的 多样性与分布格局, Biodiversity and distribution patterns of Triplophysa species in the northeastern margin of the Tibetan Plateau, 生物多样性, 2017, 第 8 作者(53) Transcriptomic profiling of Tibetan highland fish (Gymnocypris przewalskii) in response to the infection of parasite ciliate Ichthyophthirius multifiliis, FISH & SHELLFISH IMMUNOLOGY, 2017, 第 5 作者 通讯作者(54) 高原裸裂尻鱼头部轮廓形状及其变异的几何形态测量分析, GEOMETRIC MORPHOMETRICS OF THE CEPHALIC CONTOUR AND ITS MORPHOLOGICAL VARIATIONS AMONGSCHIZOPYGOPSIS STOLICZKAI(TELEOSTEI: CYPRINIDAE), 水生生物学报, 2017, 第 10 作者(55) The complete mitochondrial genome of Gymnocypris przewalskii kelukehuensis (Teleostei: Cyprinidae), CONSERVATION GENETICS RESOURCES, 2017, 第 3 作者 通讯作者(56) Comparative cytogenetics of two sympatric species (Gymnocypris, Schizothoracinae) from the Lake Langcuo, Qinghai-Tibet Plateau, CARYOLOGIA, 2016, 第 5 作者 通讯作者(57) Positive Darwinian selection within interferon regulatory factor genes of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau, FISH AND SHELLFISH IMMUNOLOGY, 2016, 第 7 作者(58) Signature of adaptive evolution and functional divergence of TLR signaling pathway genes in Tibetan naked carp Gymnocypris przewalskii, FISH & SHELLFISH IMMUNOLOGY, 2016, 第 2 作者(59) Mito-nuclear phylogeography of the cyprinid fish Gymnodiptychus dybowskii in the arid Tien Shan region of Central Asia, BIOLOGICAL JOURNAL OF THE LINNEAN SOCIETY, 2016, 第 8 作者 通讯作者(60) Isolation and characterization of ten polymorphic microsatellite loci from Gymnocypris chui and cross-amplification in seven highly specialized Schizothoracinae fishes, JOURNAL OF APPLIED ICHTHYOLOGY, 2016, (61) Mitogenomic perspectives on the origin of Tibetan loaches and their adaptation to high altitude, SCIENTIFIC REPORTS, 2016, 第 4 作者(62) Positive Darwinian selection within interferon regulatory factor genes of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau, FISH & SHELLFISH IMMUNOLOGY, 2016, 第 7 作者 通讯作者(63) Phylogeography of Diptychus maculatus (Cyprinidae) endemic to the northern margin of the QTP and Tien Shan region, BMCEVOLUTIONARYBIOLOGY, 2016, 第 4 作者 通讯作者(64) Taxonomic status of a population of Gymoncypris waddelli Regan, 1905 (Cypriniformes: Schizothoracinae) distributed in Pengqu River, Tibet, China, ZOOTAXA, 2016, 第 5 作者 通讯作者(65) Transcriptome-wide identification, molecular evolution and expression analysis of Toll-like receptor family in a Tibet fish, Gymnocypris przewalskii, FISH & SHELLFISH IMMUNOLOGY, 2015, 第 6 作者 通讯作者(66) Characterization of two paralogous myostatin genes and evidence for positive selection in Tibet fish: Gymnocypris przewalskii, GENE, 2015, 第 9 作者 通讯作者(67) Transcriptome profiling analysis of naked carp (Gymnocypris przewalskii) provides insights into the immune-related genes in highland fish, FISH & SHELLFISH IMMUNOLOGY, 2015, 第 4 作者 通讯作者(68) The biogeography and phylogeny of schizothoracine fishes (Schizopygopsis) in the Qinghai-Tibetan Plateau, ZOOLOGICA SCRIPTA, 2015, 第 8 作者(69) Transcriptome-wide identification, molecular evolution and expression analysis of Toll-like receptor family in a Tibet fish, Gymnocypris przewalskii, FISH AND SHELLFISH IMMUNOLOGY, 2015, 第 6 作者(70) Local adaptation of Gymnocypris przewalskii (Cyprinidae) on the Tibetan Plateau, SCIENTIFIC REPORTS, 2015, 第 8 作者 通讯作者(71) 不同生境下青海湖裸鲤(Gymnocypris przewalskii)两亚种鳃形态差异及其功能适应, 动物学研究, 2013, 第 5 作者(72) 青海湖裸鲤线粒体DNA D-loop区的遗传多样性及其遗传分化研究, Genetic Diversity and Differentiation of Mitochondrial DNA D-loop Region in Gymnocypdsprzewalskii, 中国农学通报, 2013, 第 5 作者(73) Ongoing Speciation in the Tibetan Plateau Gymnocypris Species Complex, PLOS ONE, 2013, 第 8 作者 通讯作者(74) Microsatellite Development for an Endangered Bream Megalobrama pellegrini (Teleostei, Cyprinidae) Using 454 Sequencing, INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 第 3 作者(75) Phylogeography of the endemic Gymnocypris chilianensis (Cyprinidae): Sequential westward colonization followed by allopatric evolution in response to cyclical Pleistocene glaciations on the Tibetan Plateau, MOLECULAR PHYLOGENETICS AND EVOLUTION, 2011, 第 1 作者(76) The youngest split in sympatric schizothoracine fish (Cyprinidae) is shaped by ecological adaptations in a Tibetan Plateau glacier lake, MOLECULAR ECOLOGY, 2009, 第 1 作者(77) Comparative phylogeography of the Yellow River schizothoracine fishes (Cyprinidae): Vicariance, expansion, and recent coalescence in response to the Quaternary environmental upheaval in the Tibetan Plateau, MOLECULAR PHYLOGENETICS AND EVOLUTION, 2009, 第 2 作者(78) Origin of Gymnocypris przewalskii and phylogenetic history of Gymnocypris eckloni (Teleostei : Cyprinidae), PROGRESS IN NATURAL SCIENCE, 2007, 第 1 作者(79) Molecular phylogenetics of Gymnocypris (Teleostei : Cyprinidae) in Lake Qinghai and adjacent drainages, CHINESE SCIENCE BULLETIN, 2005,
科研活动
科研项目
( 1 ) 全基因组藏羊优异性状分子元件解析与育种利用技术研发, 负责人, 地方任务, 2022-01--2024-12( 2 ) 青藏高原冰川湖泊两种高原鳅属鱼类的同域物种分化及其分子生态学 机制, 负责人, 国家任务, 2021-01--2024-12( 3 ) 呼伦贝尔生态草牧业科技示范工程, 负责人, 中国科学院计划, 2017-01--2018-06( 4 ) 农牧交错带生态产业技术与新兴产业培育, 负责人, 国家任务, 2016-07--2020-12( 5 ) 高原极端环境下鱼类的趋同进化研究, 负责人, 国家任务, 2016-01--2019-12( 6 ) 裂腹鱼健康养殖模式与环境协调整装技术集成示范, 参与, 中国科学院计划, 2016-01--2017-12( 7 ) 鲤等耐低氧、低温、高盐的分子模块解析, 参与, 中国科学院计划, 2013-01--2016-12( 8 ) 裂腹鱼类中同域物种形成模式的探索, 负责人, 国家任务, 2012-01--2015-12( 9 ) 鱼类生殖与抗病抗逆的基础研究, 参与, 中国科学院计划, 2011-01--2014-12( 10 ) 裂腹鱼进化基因组学与功能基因研究, 负责人, 中国科学院计划, 2010-01--2013-12
参与会议
(1)逊木错湖裸鲤同域的物种形成 中国鱼类学会2010年学术研讨会 赵凯 2010-08-01