基本信息
韩方普  男  博导  中国科学院遗传与发育生物学研究所
电子邮件: fphan@genetics.ac.cn
通信地址: 中国科学院遗传与发育生物学研究所
邮政编码: 100101

招生信息

   
招生专业
071007-遗传学
071009-细胞生物学
090102-作物遗传育种
招生方向
植物分子遗传学
植物细胞生物学

工作经历

   
工作简历
2004-03~2009-04,美国密苏里大学生物学系, 博士后
2001-01~2004-03,加拿大农业部, Visiting Fellow & Biologist
1998-08~2001-01,以色列 Weizmann 研究所, 博士后
社会兼职
2014-01-10-今,PAG Plant Chromosome Biology workshop, 召集人
2013-01-01-今,作物学报, 编委

教授课程

分子细胞遗传学
遗传学实验
遗传学实验课
遗传发育学系列讲座

专利与奖励

   
奖励信息
(1) 中科院遗传所益海嘉里优秀教师奖, 一等奖, 研究所(学校), 2014
专利成果
( 1 ) 小麦-长穗偃麦草抗赤霉病易位系的选育方法及分子标记, 2018, 第 1 作者, 专利号: 201710462612.6

( 2 ) 一种基因编辑系统及应用其对植物基因组进行编辑的方法, 2018, 第 1 作者, 专利号: 201710599030.2

( 3 ) 一种快速分析和鉴定小麦外源染色体的多色荧光原位杂交方法, 2016, 第 1 作者, 专利号: 20131027485.6

出版信息

   
发表论文
(1) Knl1 participates in spindle assembly checkpoint signaling in maize, PNAS, 2021, 通讯作者
(2) Phosphorylation of histone H3 by Haspin regulates chromosome alignment and segregation during mitosis in maize, J Exp Bot, 2021, 通讯作者
(3) Sequence of the supernumerary B chromosome of maize provides insight into its drive mechanism and evolution, PNAS, 2021, 通讯作者
(4) Genome-wide mapping reveals R-loops associated with centromeric repeats in maize, Genome Research, 2021, 通讯作者
(5) Rapid Birth or Death of Centromeres on Fragmented Chromosomes in Maize, Plant Cell, 2020, 通讯作者
(6) Back-spliced RNA from retrotransposon binds to centromere and regulates centromeric chromatin loops in maize., PLOS Biology, 2020, 通讯作者
(7) The Cohesin Complex Subunit ZmSMC3 Participates in Meiotic Centromere Pairing in Maize., Plant Cell, 2020, 通讯作者
(8) Phosphorylation of histone H3 by Haspin regulates chromosome alignment and segregation in maize mitosis, J Exp Bot, 2020, 通讯作者
(9) Centromere Satellite Repeats Have Undergone Rapid Changes in Polyploid Wheat Subgenomes, Plant Cell, 2019, 通讯作者
(10) The deposition of CENH3 in maize is stringtently regulated, Plant Journal, 2019, 通讯作者
(11) High efficiency genome editing by using dmc1 promoter-controlled CRISPR/Cas9 system in maize, Plant Biotechnology Journal, 2018, 通讯作者
(12) The Behavior of the Maize B Chromosome and Centromere., Genes, 2018, 通讯作者
(13) Barbara McClintock's Unsolved Chromosomal Mysteries: Parallels to Common Rearrangements and Karyotype Evolution., Plant Cell, 2018, 第 2 作者
(14) Meiotic Studies on Combinations of Chromosomes With Different Sized Centromeres in Maize., Front Plant Sci, 2018, 第 1 作者
(15) Site-specific transfer of chromosomal segments and genes in wheat engineered chromosomes., J Genet Genomics., 2017, 通讯作者
(16) Cohesion and centromere activity are required for phosphorylation of histone H3 in maize., Plant Journal, 2017, 通讯作者
(17) Centromere structure and function analysis in wheat-rye translocation lines., Plant Journal, 2017, 通讯作者
(18) De nove centromere formation and centromeric sequence expansion in wheat and its wide hybrids., PLOS Genetics, 2016, 通讯作者
(19) Dynamic chromatin changes associated with de novo centromere formation in maize euchromatin, Plant Journal, 2016, 通讯作者
(20) Sequential de novo centromere formation and inactivation on a chromosomal fragment in maize, Proc Natl Acad Sci U S A , 2015, 通讯作者
(21) Asymmetric epigenetic modification and elimination of rDNA sequences by polyploidization in wheat, Plant Cell, 2014, 通讯作者
(22) Characterization of two CENH3 genes and their roles in wheat evolution, New Phytol, 2014, 通讯作者
(23) Centromere pairing in early meiotic prophase requires active centromeres and precedes installation of the synaptonemal complex in maize, Plant Cell, 2013, 通讯作者
(24) De novo centromere formation on a chromosome fragment in maize, Proc Natl Acad Sci U S A, 2013, 通讯作者
(25)  A functional centromere after loss of centromeric and gain of ectopic sequences, Plant Cell, 2013, 通讯作者
(26) Phosphorylation of H2A is associated with centromere function and maintenance in meiosis, Plant J, 2012, 通讯作者
(27) Epigenetic aspects of centromere function in plants. , Current Opinion in Plant Biology, 2011, 通讯作者
(28) istinct DNA methylation patterns associated with active and inactive centromeres of the maize B chromosome.,  Genome Res. , 2011, 第 2 作者
(29) Inactivation of a centromere during the formation of a translocation in maize.,  Chromosome Research, 2011, 第 4 作者
(30) Centromere inactivation and reactivation reveal both genetic and epigenetic components for centromere specification, The Plant Cell, 2009, 第 1 作者
(31) Maize Centromeres: Structure, Function and Epigenetics, Ann Review of Genetics, 2009, 第 1 作者
(32) Minichromosome analysis of chromosome pairing, disjunction and cohesion in maize,  The Plant Cell, 2007, 第 1 作者

科研活动

   
科研项目
( 1 ) 主要农作物染色体细胞工程育种, 负责人, 国家任务, 2016-07--2020-12
( 2 ) 植物减数分裂染色体配对起始及染色体分离的分子机理, 负责人, 国家任务, 2017-01--2022-12
( 3 ) 异源多倍体小麦核型稳定的遗传机制, 负责人, 国家任务, 2020-01--2024-12
( 4 ) 植物着丝粒失活及新着丝粒形成的表观遗传学研究, 负责人, 国家任务, 2020-01--2024-12