
电子邮件: binwan@rcees.ac.cn
通信地址: 北京海淀区双清路18号环境化学楼B210
邮政编码: 100085
研究领域
主要从事人工纳米材料、环境微纳米塑料和持久性有机污染物的毒理学和生物效应机制研究。近年来主持的项目包括国家973项目子课题“BDE和PFC的毒性效应与分子机制研究”,中国科学院前沿科学重点研究项目课题“PBDEs对斑马鱼的生殖发育毒性及其机制”,和国家自然科学基金“几种碳纳米材料诱导的细胞自噬效应及其毒性作用机制研究” ,“单壁碳纳米管的生物可利用性、生物可降解性及毒性效应”,“单壁碳纳米管的免疫毒理和毒理基因组学分子机制研究”,同时还参与多项国家863计划和自然基金委重大研究计划项目。
招生信息
欢迎具有生物学、毒理/医学、材料学或分析化学相关专业的同学报考。
招生专业
招生方向
教育背景
学历
学位
工作经历
2008-04~现在, 中科院生态环境研究中心, 副研究员
2007-03~现在, 中科院生态环境研究中心, 助理研究员
2004-12~现在, 美国田纳西大学, 博士后
2000-07~现在, 中国预防医学科学院, 实习研究员
工作简历
社会兼职
教授课程
出版信息
1. Oluniyi O. Fadare, Bin Wan*, Keyang Liu, Yu Yang, Lixia Zhao, Liang-Hong Guo*. Eco-corona vs protein corona: effects of humic substances on corona formation and nanoplastic particle toxicity in Daphnia magna. Environmental Science & Technology, 2020, Accepted. (IF=7.149)
2. Oluniyi O. Fadare, Bin Wan*, Lixia Zhao, Liang-Hong Guo*. Microplastics from consumer plastic food containers: Are we consuming it? Chemosphere, 2020, 253,126787. (IF=5.108)
3. KeYang Liu, Bin Wan*. An SDS-PAGE based method for the quantification of carbon black in biological samples. Analyst, 2020, 145, 3370–3375. (IF=4.019)
4. Oluniyi O. Fadare, Bin Wan*, Liang-Hong Guo*, Yan Xin, Weiping Qin, Yu Yang. Humic acid alleviates the toxicity of polystyrene nanoplastic particles to Daphnia magna. Environmental Science-Nano, 2019, 6, 1466-1477. (IF=7.704)
5. Yan Xin, Bin Wan*. A label-free quantification method for measuring graphene oxide in biological samples. Analytica Chimica Acta, 2019, 1079, 103-110. (IF=5.256)
6. Yichun Xie, Bin Wan*, Yu Yang, Xuejing Cui, Yan Xin, Liang-Hong Guo. Cytotoxicity and autophagy induction by graphene quantum dots with different functional groups. Journal of Environmental Science, 2019, 77, 198-209. (IF=3.556)
7. Xuejing Cui, Bin Wan*, Yu Yang, Yan Xin, Yi-Chun Xie, Liang-Hong Guo*, and Lin L. Mantell. Carbon Nanomaterials Stimulate HMGB1 Release From Macrophages and Induce Cell Migration and Invasion. Toxicological Sciences, 2019, 172(2), 398-410. (IF=3.564)
8. Yan Xin, Bin Wan*, Yu Yang, Xue-Jing Cui, Yi-Chun Xie, Liang-Hong Guo*. Perfluoroalkyl acid exposure induces protective mitochondrial and endoplasmic reticulum autophagy in lung cells. Archives of Toxicology, 2018, 92, 3131–3147. (IF=5.741)
9. Xuejing Cui, Bin Wan*, Yu Yang, Xiaomin Ren, Liang-Hong Guo*, Length effects on the dynamic process of cellular uptake and exocytosis of single-walled carbon nanotubes in murine macrophage cells. Scientific Reports, 2017, 7, 1518. (IF=4.011)
10. Xuejing Cui, Bin Wan*, Yu Yang, Xiaomin Ren, Liang-Hong Guo*, and Hui Zhang. Crucial Role of P2X7 Receptor in Regulating Exocytosis of Single-Walled Carbon Nanotubes in Macrophages. Small, 2016, 12, 5998-6011.(Cover Image) (IF=10.856)
11. Xuejing Cui, Bin Wan*, Liang-Hong Guo*, Yu Yang, and Xiaomin Ren. Insight into the Mechanisms of Combined Toxicity of Single-Walled Carbon Nanotubes and Nickel Ions in Macrophages: Role of P2X7 Receptor. Environmental Science & Technology, 2016, 50, 12473-12483. (IF=7.149)
12. Jie Hou, Bin Wan*, Yu Yang, Xiao-Min Ren, Liang-Hong Guo*,and Jing-Fu Liu. Biodegradation of Single-Walled Carbon Nanotubes in Macrophages through Respiratory Burst Modulation. International Journal of Molecular Sciences, 2016, 17, 409-426. (IF=4.183)
13. Qi-Yan Lv, Bin Wan*, Liang-Hong Guo*, Lixia Zhao, Yu Yang. In vitro immune toxicity of polybrominated diphenyl ethers on murine peritoneal macrophages: Apoptosis and immune cell dysfunction. Chemosphere, 2015,120, 621-630. (IF=5.108)
14. Qi-Yan Lv, Bin Wan*, Liang-Hong Guo*, Yu Yang, Xiao-Min Ren, Hui Zhang. In vivo immunotoxicity of perfluorooctane sulfonate in BALB/c mice: Identification of T-cell receptor and calcium-mediated signaling pathway disruption through gene expression profiling of the spleen. Chemico-Biological Interactions, 2015, 240, 84-93. (IF=3.407)
15. Ping-Xuan Dong, Bin Wan*, Zi-Xia Wang, Liang-Hong Guo*, Yu Yang & Lixia Zhao. Exposure of single-walled carbon nanotubes impairs the functions of primarily cultured murine peritoneal macrophages. Nanotoxicology, 2013, 7(5): 1028-1042. (IF=5.955)
16. Bin Wan* , Zi-Xia Wang, Qi-Yan Lv, Ping-Xuan Dong, Li-Xia Zhao, Yu Yang, Liang-Hong Guo*. Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages. Toxicology Letters, 2013, 221, 118-127. (IF=3.499)
17. Ping-Xuan Dong, Bin Wan* and Liang-Hong Guo. In vitro toxicity of acid-functionalized Single-Walled Carbon Nanotubes: Effects on Murine Macrophages and Gene Expression Profiling. Nanotoxicology, 2012, 6(3), 288-303. (IF=5.955)
18. 万斌*,郭良宏. 多溴联苯醚的环境毒理学研究进展.环境化学, 2011, 30, 143-152.
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指导学生
已指导学生
汪子霞 硕士研究生 430130-环境工程
侯杰 硕士研究生 085238-生物工程
现指导学生
谢懿春 硕士研究生 077601-环境科学