070303-有机化学

有机氟化学
有机合成

1998-09--2003-07   中国科学院上海有机化学研究所   博士
1994-09--1998-07   四川大学   学士

   

2020-04~现在, 中国科学院上海有机化学研究所, 实验室主任
2012-01~现在, 中国科学院上海有机化学研究所, 研究员 所聘**
2008-05~2011-12,中国科学院上海有机化学研究所, 副研究员课题组长
2003-08~2008-03,美国伊利诺伊大学香槟分校（UIUC), 博士后研究助理
1998-09~2003-07,中国科学院上海有机化学研究所, 博士
1994-09~1998-07,四川大学, 学士

2023-01-01-2025-12-31,双聘教授, 教授
2019-04-15-2024-04-14,兼职教授, 教授

有机氟化学

   

（1） 中国化学会黄维垣氟化学奖, , 其他, 2021
（2） “万人计划”科技创新领军人才, , 其他, 2018
（3） 科技部中青年科技创新领军人才, 国家级, 2016
（4） 第五届中国化学会—英国皇家化学会青年化学家奖, 其他, 2015
（5） 2015 RSC Fluorine Chemistry Prize, 其他, 2015
（6） 2015年上海市科技系统青年五四奖章, 其他, 2015
（7） Thieme Chemistry Journal Award, 其他, 2014
（8） 中国科学院“优秀研究生指导教师”奖, 院级, 2013
（9） 上海市启明星计划, 其他, 2009

（ 1 ） 合成含二氟亚甲基烷烃类化合物的方法, 2022, 第 1 作者, 专利号: CN114195703A

（ 2 ） 一类含氟化合物及其应用, 2021, 第 1 作者, 专利号: CN113429259A

（ 3 ） 一种氟吡嗪化合物的制备方法, 2021, 第 1 作者, 专利号: CN113072507A

（ 4 ） 一种三氟乙基类化合物的制备方法, 2020, 第 1 作者, 专利号: CN110668913A

（ 5 ） 镍盐催化高效合成具有三氟甲基苄基卤化物结构的化合物及其转化应用, 2020, 第 1 作者, 专利号: CN110668941A

（ 6 ） 一种含氟甲基的化合物及其制备方法, 2019, 第 1 作者, 专利号: CN109694350A

（ 7 ） 一种α-芳基、杂芳基或烯基-α,α-二氟甲基类化合物的制备方法, 2018, 第 1 作者, 专利号: CN108341739A

（ 8 ） 含一氟烷基的化合物、其制备方法及应用, 2017, 第 1 作者, 专利号: CN106278847A

（ 9 ） 含二氟烷基取代的芳基或杂芳基化合物、制备方法和应用, 2016, 第 1 作者, 专利号: CN105669365A

（ 10 ） 含二氟炔丙基的化合物、制备方法及应用, 2016, 第 1 作者, 专利号: CN105272997A

（ 11 ） 含二氟亚甲基的化合物及其制备方法, 2016, 第 1 作者, 专利号: CN105272792A

（ 12 ） 钯催化合成α-芳基、杂芳基或烯基-α,α-二氟烯丙基结构的方法, 2015, 第 1 作者, 专利号: CN104692985A

（ 13 ） 一种氟代苯并杂环-杂芳环结构的合成方法, 2015, 第 1 作者, 专利号: CN104672221A

（ 14 ） 含氟芳烃衍生物的选择性氢化还原方法, 2013, 第 1 作者, 专利号: CN103193568A

（ 15 ） 一种噻吩环/呋喃环-杂芳环结构的合成方法, 2013, 第 1 作者, 专利号: CN103030627A

（ 16 ） 一种多氟芳烃-杂芳环砌块的合成方法, 2012, 第 1 作者, 专利号: CN102503747A

   

（1） Recent advances in the synthesis of fluorinated amino acids and peptides, CHEMICAL COMMUNICATIONS, 2023, 第 11 作者
（2） Copper-Catalyzed Difluorocarbene Transfer Enables Modular Synthesis, Nature Chemistry, 2023, 第 11 作者
（3） Nickel-Catalyzed Multicomponent Carbodifluoroalkylation of Electron-Deficient Alkenes, Acs Catalysis, 2023, 第 11 作者
（4） Reductive Catalytic Difluorocarbene Transfer via Palladium Catalysis, Angew. Chem. Int. Ed., 2023, 
（5） Enantioselective nickel-catalyzed dicarbofunctionalization of 3,3,3-trifluoropropene, NATURE COMMUNICATIONS, 2022, 第 11 作者
（6） Nickel-catalyzed alkyl-arylation of 3,3,3-trifluoropropene, COMMUNICATIONS CHEMISTRY, 2022, 第 11 作者
（7） Coupling of Heteroaryl Halides with Chlorodifluoroacetamides and Chlorodifluoroacetate via Nickel Catalysis, Chemistry - A European Journal, 2022, 第 11 作者
（8） (Fluoro)alkylation of alkenes promoted by photolysis of alkylzirconocenes, CHEMICAL SCIENCE, 2022, 第 11 作者
（9） 3,3-Difluoroallyl Sulfonium Salts: Practical and Bench-Stable Reagents for Highly Regioselective gem-Difluoroallylations, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 11 作者
（10） Highly ���-Selective Arylation and Carbonylative Arylation of 3-Bromo-3,3-difluoropropene via Nickel Catalysis, Angewandte Chemie International Edition, 2021, 第 11 作者
（11） Palladium-Catalyzed Carbonylative Cross-Coupling of Difluoroalkyl Halides with Alkylboranes under 1 atm of CO, ORGANIC LETTERS, 2021, 第 11 作者
（12） Visible-Light-Induced Palladium-Catalyzed Selective Defluoroarylation of Trifluoromethylarenes with Arylboronic Acids, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2021, 第 11 作者
（13） Nickel-Catalyzed Four-Component Carbocarbonylation of Alkenes under 1 atm of CO, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 第 11 作者
（14） 镍催化下3，3，3-三氟丙烯与芳基锌试剂的区域选择性偶联反应, Nickel-Catalyzed Regioselective Coupling Reaction of 3,3,3-Trifluoropropene with Arylzinc Reagents, 有机化学, 2020, 第 11 作者
（15） Stereoselective Functionalization of Racemic Cyclopropylzinc Reagents via Enantiodivergent Relay Coupling, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2020, 第 11 作者
（16） trans-Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides by Nickel Catalysis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 第 11 作者
（17） Decarboxylative and Deaminative Alkylation of Difluoroenoxysilanes via Photoredox Catalysis: A General Method for Site-Selective Synthesis of Difluoroalkylated Alkanes, ORGANIC LETTERS, 2020, 第 11 作者
（18） Palladium Difluorocarbene Involved Catalytic Coupling with Terminal Alkynes, CCS Chem., 2020, 第 11 作者
（19） Nickel-Catalyzed Carbonylation of Secondary Trifluoromethylated, Difluoromethylated, and Nonfluorinated Aliphatic Electrophiles with Arylboronic Acids under 1 atm of CO, ACS CATALYSIS, 2020, 第 11 作者
（20） Copper-Catalyzed Highly Enantioselective Difluoroalkylation of Secondary Propargyl Sulfonates with Difluoroenoxysilanes, CHEM, 2019, 第 11 作者
（21） Palladium-catalyzed cross-coupling of unactivated alkylzinc reagents with 2-bromo-3,3,3-trifluoropropene and its application in the synthesis of fluorinated amino acids, CHEMICAL COMMUNICATIONS, 2019, 第 11 作者
（22） 镍催化下一溴二氟甲烷对（杂）芳基溴代物的二氟甲基化反应, Nickel-Catalyzed Difluoromethylation of (Hetero)aryl Bromides with BrCF2H, 有机化学, 2019, 第 3 作者
（23） Nickel-Catalyzed Carbonylation of Difluoroalkyl Bromides with Arylboronic Acids, ORGANIC LETTERS, 2019, 第 11 作者
（24） Visible light promoted fluoroalkylation of alkenes and alkynes using 2-bromophenol as a catalyst, CHEMICAL COMMUNICATIONS, 2019, 第 11 作者
（25） Ni-Catalyzed Defluorination for the Synthesis of gem-Difluoro-1,3-dienes and Their 4+2 Cycloaddition Reaction, ORGANICLETTERS, 2019, 第 11 作者
（26） Fluoroalkylation-Borylation of Alkynes: An Efficient Method To Obtain (Z)-Tri- and Tetrasubstituted Fluoroalkylated Alkenylboronates, ACS CATALYSIS, 2019, 第 11 作者
（27） 镍催化下一溴二氟甲烷对（杂）芳基溴代物的二氟甲基化反应, Nickel-Catalyzed Difluoromethylation of (Hetero)aryl Bromides with BrCF_2H, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 第 11 作者
（28） Controllable catalytic difluorocarbene transfer enables access to diversified fluoroalkylated arenes, NATURE CHEMISTRY, 2019, 第 11 作者
（29） 镍催化下一溴二氟甲烷对（杂）芳基溴代物的二氟甲基化反应, Nickel-Catalyzed Difluoromethylation of (Hetero)aryl Bromides with BrCF_2H, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2019, 第 11 作者
（30） Iron-Catalyzed Cross-Coupling of Diarylzinc or Aryl Grignard Reagents with Difluoroalkyl Bromides, ACTA CHIMICA SINICA, 2018, 第 11 作者
（31） Catalyst-free and visible light promoted trifluoromethylation and perfluoroalkylation of uracils and cytosines, CHEMICAL COMMUNICATIONS, 2018, 第 11 作者
（32） Copper-Catalyzed Highly Stereospecific Trifluoromethylation and Difluoroalkylation of Secondary Propargyl Sulfonates, Angew. Chem. Int. Ed., 2018, 第 11 作者
（33） Nickel-Catalyzed Difluoroalkylation of (Hetero)aryl Bromides with Unac-tivated 1-Bromo-l,l-difluoroalkanes, Nickel-Catalyzed Difluoroalkylation of (Hetero)aryl Bromides with Unac-tivated 1-Bromo-l,l-difluoroalkanes, 中国化学：英文版, 2018, 第 3 作者
（34） 六氟环氧丙烷齐聚物的合成, Preparation of Hexafluoropropylene Oxide Oligomers, 东华大学学报. 自然科学版, 2018, 第 3 作者
（35） Highly Selective Pd-Catalyzed Direct C-F Bond Arylation of Polyfluoroarenes, ORGANIC LETTERS, 2018, 第 11 作者
（36） Bulky Diamine Ligand Promoted Cross-Coupling with Difluoroalkyl Bromides via Iron Catalysis, Angew. Chem. Int. Ed., 2018, 第 11 作者
（37） Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides, ACCOUNTS OF CHEMICAL RESEARCH, 2018, 第 11 作者
（38） 铁催化下二芳基锌和芳基格氏试剂的二氟烷基化反应, Iron-Catalyzed Cross-Coupling of Diarylzinc or Aryl Grignard Reagents with Difluoroalkyl Bromides, 化学学报, 2018, 第 3 作者
（39） Nickel-Catalyzed Difluoromethylation of Arylboronic Acids with Bromodifluoromethane, Nickel-Catalyzed Difluoromethylation of Arylboronic Acids with Bromodifluoromethane, 中国化学：英文版, 2018, 第 3 作者
（40） Highly Selective Pd-Catalyzed Direct C-F Bond Arylation of Simple Polyfluoroarenes, Org. Lett., 2018, 第 11 作者
（41） Nickel-Catalyzed Difluoromethylation of Arylboronic Acids with Bromodifluoromethane, Nickel-Catalyzed Difluoromethylation of Arylboronic Acids with Bromodifluoromethane, CHINESE JOURNAL OF CHEMISTRY, 2018, 第 11 作者
（42） Catalytic difluoroalkylations through controllable difluorocarbene and radical cross-couplings and their applications in medicinal chemistry, ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2018, 第 1 作者
（43） Difluoromethylation of (hetero)aryl chlorides with chlorodifluoromethane catalyzed by nickel, NATURE COMMUNICATIONS, 2018, 第 11 作者
（44） Nickel-Catalyzed Difluoroalkylation of (Hetero)aryl Bromides with Unactivated 1-Bromo-1,1-difluoroalkanes, CHINESE JOURNAL OF CHEMISTRY, 2018, 第 11 作者
（45） Bromotrifluoromethane: A Useful Reagent for Hydrotrifluoro-methylation of Alkenes and Alkynes, SYNLETT, 2018, 第 11 作者
（46） Access to Difluoromethylene-Skipped 1,4-Diynes with gem-Difluoropropargyl Bromide, ACS CATALYSIS, 2017, 第 11 作者
（47） Visible-Light-Mediated Direct Perfluoroalkylation and Trifluoromethylation of Free Anilines, TETRAHEDRON LETTERS, 2017, 第 11 作者
（48） Visible-Light-Promoted Tandem Difluoroalkylation-Amidation: Access to Difluorooxindoles from Free Anilines, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 11 作者
（49） Highly selective nickel-catalyzed gem-difluoropropargylation of unactivated alkylzinc reagents, NATURE COMMUNICATIONS, 2017, 第 11 作者
（50） Chlorodifluoromethane-triggered formation of difluoromethylated arenes catalysed by palladium, NATURE CHEMISTRY, 2017, 第 11 作者
（51） Palladium-catalyzed Heck-type reaction of secondary trifluoromethylated alkyl bromides, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 11 作者
（52） Visible-Light-Promoted Tandem Difluoroalkylation-Amidation: Access to Difluorooxindoles from Free Anilines, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 11 作者
（53） Pd-catalyzed gem-difluoroallylation of arylboronic acids with gamma,gamma-difluoroallylic acetates, CHEMICAL COMMUNICATIONS, 2016, 第 11 作者
（54） Access to Difluoromethylated Arenes by Pd-Catalyzed Reaction of Arylboronic Acids with Bromodifluoroacetate, ORGANIC LETTERS, 2016, 第 11 作者
（55） Tandem Difluoroalkylation-Arylation of Enamides Catalyzed by Nickel, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 第 11 作者
（56） Palladium-catalyzed phosphonyldifluoromethylation of alkenes with bromodifluoromethylphosphonate, ORGANIC CHEMISTRY FRONTIERS, 2016, 第 11 作者
（57） Copper-Catalyzed Direct Propargylation of Polyfluoroarenes with Secondary Propargyl Phosphates, ORGANIC LETTERS, 2016, 第 11 作者
（58） Bronsted Acid Catalyzed gem-Difluoroallylation of Aldehydes and Ketone with beta-Tosyloxy-y,y-difluroallylboronic Acid Pinacol Ester, CHINESE JOURNAL OF CHEMISTRY, 2016, 第 11 作者
（59） Nickel-Catalyzed Difluoroalkylation of (Hetero)Arylborons with Unactivated 1-Bromo-1,1-difluoroalkanes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 第 11 作者
（60） Carbonylation of Difluoroalkyl Bromides Catalyzed by Palladium, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 第 11 作者
（61） Palladiium-Catalyzed Phosphonyldifluoromethylation of Alkenes with Bromodifluoromethyphosphonate, Org. Chem. Front., 2016, 第 11 作者
（62） Bronsted Acid Catalyzed gem-Difluoroallylation of Aldehydes and Ketone with β-Tosyloxy-γ,γ-difluroallylboronic Acid Pinacol Ester, Bronsted Acid Catalyzed gem-Difluoroallylation of Aldehydes and Ketone with ��-Tosyloxy-��,��-difluroallylboronic Acid Pinacol Ester, 中国化学：英文版, 2016, 第 2 作者
（63） Bronsted Acid Catalyzed gem-Difluoroallylation of Aldehydes and Ketone with j3-Tosyloxy-Y, Y-difluroallylboronic Acid Pinacol Ester, CHINESE JOURNAL OF CHEMISTRY, 2016, 第 2 作者
（64） Nickel-Catalyzed Reductive Cross-Coupling of (Hetero)Aryl Iodides with Fluorinated Secondary Alkyl Bromides, ORGANIC LETTERS, 2015, 第 4 作者
（65） Palladium-Catalyzed Heck-Type Difluoroalkylation of Alkenes with Functionalized Difluoromethyl Bromides, SYNTHESISSTUTTGART, 2015, 第 11 作者
（66） 镍催化的芳基硼酸偕二氟炔丙基化反应, Nickel-Catelyzed Cross-Coupling of gem-Difluorpropargyl Bromide with Aryl Boronic Acids, 化学学报, 2015, 第 3 作者
（67） Nickel-Catalyzed Cross-Coupling of gem-Difluoropropargyl Bromide with Aryl Boronic Acids, ACTA CHIMICA SINICA, 2015, 第 3 作者
（68） Synthesis of diaryldifluoromethanes by Pd-catalyzed difluoroalkylation of arylboronic acids, ORGANIC CHEMISTRY FRONTIERS, 2015, 第 3 作者
（69） Rhodium-Catalyzed ortho-Selective C-F Bond Borylation of Polyfluoroarenes with Bpin-Bpin, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 第 11 作者
（70） A General Synthesis of Fluoroalkylated Alkenes by Palladium-Catalyzed Heck-Type Reaction of Fluoroalkyl Bromides, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 第 11 作者
（71） Palladium-Catalyzed Difluoroalkylation of Isocyanides: Access to Difluoroalkylated Phenanthridine Derivatives, ORGANIC LETTERS, 2015, 第 11 作者
（72） Facile Access to Fluoromethylated Arenes by Nickel-Catalyzed Cross-Coupling between Arylboronic Acids and Fluoromethyl Bromide, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 第 11 作者
（73） Palladium-Catalyzed Direct Thienylation of Monobromide-Substituted Difluorinated Benzothiadiazoles for Organic Photovoltaics, SYNLETT, 2015, 第 4 作者
（74） Nickel-Catalyzed Cross-Coupling of Functionalized Difluoromethyl Bromides and Chlorides with Aryl Boronic Acids: A General Method for Difluoroalkylated Arenes, ANGEW. CHEM.-INT. EDIT., 2014, 第 5 作者
（75） Direct (Het)Arylation of Fluorinated Benzothiadiazoles and Benzotriazole with (Het)Aryl Iodides, JOURNAL OF ORGANIC CHEMISTRY, 2014, 第 11 作者
（76） Highly Selective gem-Difluoroallylation of Organoborons with Bromodifluoromethylated Alkenes Catalyzed by Palladium, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 第 11 作者
（77） Pd-Catalyzed Difluoroalkylation of Arylboronic Acids: A New Method for Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives, Angew. Chem., Int. Ed., 2014, 第 11 作者
（78） Copper-catalyzed cross-coupling of bromozinc-difluoromethylphosphonate with iodo/bromo-aryl triazenes, ORGANIC CHEMISTRY FRONTIERS, 2014, 第 3 作者
（79） Highly Selective gem-Difluoroallylation of Organoborons with Bromodifluoromethylated Alkenes Catalyzed by Palladium, J. AM. CHEM. SOC., 2014, 第 5 作者
（80） Pd-catalyzed cross-coupling of polyfluoroarenes with cyclic vinyl triflates, SCI. CHINA-CHEM., 2014, 第 3 作者
（81） Palladium-Catalyzed Difluoroalkylation of Aryl Boronic Acids: A New Method for the Synthesis of Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 第 11 作者
（82） Direct Olefination of Fluorinated Benzothiadiazoles: A New Entry to Optoelectronic Materials, CHEM.-EUR. J., 2014, 第 4 作者
（83） Selective thienylation of fluorinated benzothiadiazoles and benzotriazoles for organic photovoltaics, CHEM. SCI., 2014, 第 4 作者
（84） Direct Olefination of Fluorinated Benzothiadiazoles: A New Entry to Optoelectronic Materials, CHEMISTRY-A EUROPEAN JOURNAL, 2014, 第 11 作者
（85） Selective thienylation of fluorinated benzothiadiazoles and benzotriazoles for organic photovoltaics, CHEMICAL SCIENCE, 2014, 第 11 作者
（86） Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes, ORG. LETT., 2014, 第 4 作者
（87） Palladium-Catalyzed Difluoroalkylation of Aryl Boronic Acids: A New Method for the Synthesis of Aryldifluoromethylated Phosphonates and Carboxylic Acid Derivatives, ANGEW. CHEM.-INT. EDIT., 2014, 第 5 作者
（88） Nickel-Catalyzed Cross-Coupling of Functionalized Difluoromethyl Bromides and Chlorides with Aryl Boronic Acids: A General Method for Difluoroalkylated Arenes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 第 11 作者
（89） Copper-Catalyzed Aerobic Oxidative Annulation and Carbon-Carbon Bond Cleavage of Arylacetamides: Domino Synthesis of Fused Quinazolinones, ORG. CHEM. FRONT., 2014, 第 3 作者
（90） Pd-catalyzed aerobic direct olefination of polyfluoroarenes, TETRAHEDRON LETTERS, 2014, 第 3 作者
（91） Pd-catalyzed aerobic direct olefination of polyfiuoroarenes, TETRAHEDRON LETTERS, 2014, 第 11 作者
（92） Heteroaryldifluoromethylation of Organoborons Catalyzed by Palladium: Facile Access to Aryl(Heteroaryl)difluoromethanes, ORGANIC LETTERS, 2014, 第 11 作者
（93） Synthesis of alpha,alpha-Difluoromethylene Alkynes by Palladium-Catalyzed gem-Difluoropropargylation of Aryl and Alkenyl Boron Reagents, ANGEW. CHEM.-INT. EDIT., 2014, 第 3 作者
（94） Synthesis of alpha,alpha-Difluoromethylene Alkynes by Palladium-Catalyzed gem-Difluoropropargylation of Aryl and Alkenyl Boron Reagents, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 第 11 作者
（95） Pd-catalyzed cross-coupling of polyfluoroarenes with cyclic vinyl triflates, SCIENCE CHINA-CHEMISTRY, 2014, 第 11 作者
（96） Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes, CHEM. SCI., 2013, 第 5 作者
（97） Nickel-Catalyzed ortho-Selective Hydrodefluorination of N-Containing Heterocycle-Polyfluoroarenes, CHIN. J. CHEM., 2013, 第 4 作者
（98） Construction of Optically Active Quaternary Propargyl Amines by Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of Ketoimines, CHEMISTRY-A EUROPEAN JOURNAL, 2013, 第 11 作者
（99） Thioether-Promoted Direct Olefination of Polyfluoroarenes Catalyzed by Palladium, ORGANIC LETTERS, 2013, 第 11 作者
（100） Thioether-Promoted Direct Olefination of Polyfluoroarenes Catalyzed by Palladium, ORG. LETT., 2013, 第 4 作者
（101） Pd-Catalyzed Direct Arylation of Nitro(pentafluorosulfanyl)benzenes with Aryl Bromides, ORGANIC LETTERS, 2013, 第 11 作者
（102） Palladium-Catalyzed Ortho-Selective C-F Activation of Polyfluoroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics, ANGEW. CHEM.-INT. EDIT., 2013, 第 5 作者
（103） Palladium-Catalyzed ortho-Selective C-F Activation of Polyfluroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics, Angew. Chem. Int. Ed., 2013, 第 11 作者
（104） Pd-catalyzed oxidative cross-coupling between two electron rich heteroarenes, CHEMICAL SCIENCE, 2013, 第 11 作者
（105） Construction of Optically Active Quaternary Propargyl Amines by Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of Ketoimines, CHEM.-EUR. J., 2013, 第 3 作者
（106） Palladium-Catalyzed Ortho-Selective C-F Activation of Polyfluoroarenes with Triethylsilane: A Facile Access to Partially Fluorinated Aromatics, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 第 11 作者
（107） Nickel-Catalyzed ortho-Selective Hydrodefluorination of N-Containing Heterocycle-Polyfluoroarenes, CHINESE JOURNAL OF CHEMISTRY, 2013, 第 11 作者
（108） Pd-Catalyzed Direct Arylation of Nitro(pentafluorosulfanyl)benzenes with Aryl Bromides, ORG. LETT., 2013, 第 4 作者
（109） Palladium-Catalyzed Aerobic Dehydrogenative Cross-Coupling of Polyfluoroarenes with Thiophenes: Facile Access to Polyfluoroarene-Thiophene Structure, ORGANOMETALLICS, 2012, 第 11 作者
（110） Copper- and Phosphine-Ligand-Free Palladium-Catalyzed Direct Allylation of Electron-Deficient Polyfluoroarenes with Allylic Chlorides, CHEMISTRY-A EUROPEAN JOURNAL, 2012, 第 11 作者
（111） Pd-Catalyzed Dehydrogenative Cross-Coupling of Polyfluoroarenes with Heteroatom-Substituted Enones, ORGANIC LETTERS, 2012, 第 11 作者
（112） Pd-Catalyzed Direct Arylation of Polyfluoroarenes on Water under Mild Conditions Using PPh3 Ligand, J. ORG. CHEM., 2012, 第 3 作者
（113） Copper Catalyzed Cross-Coupling of Iodobenzoates with Bromozinc-difluorophosphonate, ORGANIC LETTERS, 2012, 第 11 作者
（114） Pd-Catalyzed Dehydrogenative Cross-Coupling of Polyfluoroarenes with Heteroatom-Substituted Enones, ORG. LETT., 2012, 第 6 作者
（115） Copper-Catalyzed Dehydrogenative Cross-Coupling of Benzothiazoles with Thiazoles and Polyfluoroarene, ORGANIC LETTERS, 2012, 第 11 作者
（116） Pd-Catalyzed Direct Arylation of Polyfluoroarenes on Water under Mild Conditions Using PPh3 Ligand, JOURNAL OF ORGANIC CHEMISTRY, 2012, 第 11 作者
（117） Copper Catalyzed Cross-Coupling of Iodobenzoates with Bromozinc-difluorophosphonate, ORG. LETT., 2012, 第 3 作者
（118） Copper-Catalyzed Oxidative Trifluoromethylthiolation of Aryl Boronic Acids with TMSCF3 and Elemental Sulfur, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 第 5 作者
（119） Highly Diastereoselective Synthesis of Quaternary ?-Trifluoromethyl ?-Amino Acids by Addition of Benzylzinc Reagents to Chiral Imines of Tifluoropyruvate, Tetrahedron Lett, 2011, 第 11 作者
（120） Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids by addition of benzylzinc reagents to chiral imines of trifluoropyruvate, TETRAHEDRON LETTERS, 2011, 第 11 作者
（121） Direct Palladium-Catalyzed Intermolecular Allylation of Highly Electron-Deficient Polyfluoroarenes, ANGEW. CHEM.-INT. EDIT., 2011, 第 3 作者
（122） Pd-catalyzed Highly Regio- and Stereocontrolled Direct Alkenylation of Electron-deficient Polyfluoroarenes, CHEMISTRY LETTERS, 2011, 第 11 作者
（123） Pd-Catalyzed Direct Cross-Coupling of Electron-Deficient Polyfluoroarenes with Heteroaromatic Tosylates, ORGANIC LETTERS, 2011, 第 11 作者
（124） Pd-Catalyzed Direct Cross-Coupling of Electron-Deficient Polyfluoroarenes with Heteroaromatic Tosylates, ORG. LETT., 2011, 第 3 作者
（125） Pd-catalyzed Highly Regio- and Stereocontrolled Direct Alkenylation of Electron-deficient Polyfluoroarenes, CHEM. LETT., 2011, 第 2 作者
（126） Highly enantioselective zinc/BINOL-catalyzed alkynylation of alpha-ketoimine ester: a new entry to optically active quaternary alpha-CF3 alpha-amino acids, CHEMICAL COMMUNICATIONS, 2011, 第 11 作者
（127） 锌（BINOL）催化下炔对a-酮酸酯亚胺的高立体选择性加成反应, Highly enantioselective zinc/BINOL-catalyzed alkynylation of alpha-ketoimine ester: a new entry to optically active quaternary alpha-CF(3) alpha-amino acids, CHEM. COMMUN., 2011, 第 3 作者
（128） Highly Enantioselective Zinc/BINOL-Catalyzed Alkynylation of alfa-Ketoimine Ester: A New Entry to Optically Active Quaternary alfa-CF3 alfa-Amino Acids, 2011, 第 11 作者
（129） Direct Palladium-Catalyzed Intermolecular Allylation of Highly Electron-Deficient Polyfluoroarenes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2011, 第 11 作者
（130） Diastereoselective synthesis of propargylic fluorides and its application in preparation of monofluorinated sugar, TETRAHEDRON, 2010, 第 11 作者
（131） Highly diastereoselective synthesis of quaternary alpha-trifluoromethyl alpha-amino acids from chiral imines of trifluoropyruvate, CHEMICAL COMMUNICATIONS, 2010, 第 11 作者
（132） Direct Pd-catalyzed benzylation of highly electron-deficient perfluoroarenes, CHEMICAL COMMUNICATIONS, 2010, 第 11 作者
（133） Pd(OAc)(2) Catalyzed Olefination of Highly Electron-Deficient Perfluoroarenes, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 第 11 作者
（134） Highly Diastereoselective Synthesis of Quaternary alfa-Trifluoromethyl alfa-Amino Acids from Chiral Imines of Trifluoropyruvate, Chem. Commun., 2010, 第 11 作者
（135） Pd(OAc)(2) Catalyzed Olefination of Highly Electron-Deficient Perfluoroarenes, J. AM. CHEM. SOC., 2010, 第 1 作者
（136） Pd-Catalyzed Oxidative Cross-Coupling of Perfluoroarenes with Aromatic Heterocycles, J. AM. CHEM. SOC., 2010, 第 3 作者
（137） Pd-Catalyzed Oxidative Cross-Coupling of Perfluoroarenes with Aromatic Heterocycles, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2010, 第 11 作者
（138） Direct Pd-catalyzed benzylation of highly electron-deficient perfluoroarenes, CHEM. COMMUN., 2010, 第 3 作者
（139） Stereoselective Reformatskii-Claisen rearrangement: synthesis of 2 ',3 '-dideoxy-6 ',6 '-difluoro-2 '-thionucleosides, CHEMICAL COMMUNICATIONS, 2009, 第 2 作者
（140） Synthesis and biological evaluation of potent glycosidase inhibitors: 4-deoxy-4,4-difluoroisofagomine and analogues, TETRAHEDRON, 2009, 第 4 作者
（141） Synthesis of 2,3,4-Trideoxy-4,4-difluoro-D-ribo-hexopyranose Adenosines, SYNTHESIS-STUTTGART, 2009, 第 2 作者
（142） CuBr-Catalyzed Oxidative Difluoromethylation of Tertiary Amines with Difluoroenol Silyl Ethers, ORGANIC LETTERS, 2009, 第 2 作者
（143） Highly Diastereoselective Zn/SnCl2-Mediated gem-Difluoroallylation of Chiral Hydrazones, ORGANIC LETTERS, 2009, 第 2 作者
（144） Ruthenium-catalyzed 1,3-dipolar cycloaddition of trifluoromethylated propargylic alcohols with azides, TETRAHEDRON LETTERS, 2008, 第 2 作者
（145） L-B-3'-去氧-3'，3'-二氟-4'-硫代核苷的合成, Synthesis of L-��-3'-deoxy-3',3'-difluoro-4'-thionucleosides, ORG. LETT., 2006, 第 4 作者
（146） 基于RCM反应合成含二氟亚甲基的Goniodiols和Goniothalamin过氧化物, Stereocontrolled synthesis of gem-difluoromethylenated goniodiols and goniothalamin epoxides based on ring-closing metathesis metathesis; alpha,beta-unsaturated-delta-tactone, SYNTHESIS, 2006, 第 2 作者
（147） Synthesis of L-beta-3 '-deoxy-3 ',3 '-difluoro-4 '-thionucleosides, ORGANIC LETTERS, 2006, 第 4 作者
（148） 3－脱氧－3，3－二氟－阿拉伯呋喃糖： 首次立体选择性合成和应用于制备含二氟亚甲基的核苷, 3-Deoxy-3,3-difluoro-Daradinofuranose: First stereoseoelective synthesis and application in preparation of gem-difluorinated sugar nucleosides, J. ORG. CHEM., 2003, 第 1 作者
（149） 从α-三氟甲基-α，β-不饱和酯酸合成 L-2'，3'二双去氧-2'-三氟甲基的硫代核苷, Synthesis of novel L-2',3'-dideoxy-2'-trifluoromethyl-4'-thiocytidines from��-trifluoromethyl-��,��-unsaturated ester, J. ORG. CHEM., 2002, 第 1 作者
（150） 从α三氟甲基α，β-不饱和酯出发合成2'，3'-双脱氧-2'-三氟甲基化的核苷, Synthesis of 2',3'-Dideoxy-2'-trifluoromethylnucleosides from ��-Trifluoromethyl-��,��-unsaturated ester, J. ORG. CHEM., 2000, 第 1 作者

   

（ 1 ） 多样性导向的天然药物新分子的创制, 负责人, 国家任务, 2022-01--2026-12
（ 2 ） 功能导向的含氟有机化合物的选择性合成, 负责人, 国家任务, 2020-01--2024-12
（ 3 ） 基于小分子氟烷烃的高效转化研究, 负责人, 国家任务, 2017-01--2020-12
（ 4 ） 高性能有机材料分子的创制, 负责人, 中国科学院计划, 2016-07--2021-06
（ 5 ） 有机氟化学, 负责人, 国家任务, 2015-01--2019-12
（ 6 ） 功能导向的有机氟化学, 参与, 国家任务, 2015-01--2019-12
（ 7 ） 耐极端条件的有机含氟分子的构筑方法及反应规律研究, 参与, 国家任务, 2015-01--2019-08
（ 8 ） 含氟有机功能分子的可控性合成及应用, 负责人, 国家任务, 2014-01--2018-12
（ 9 ） 多氟芳烃反应特性研究及应用, 负责人, 国家任务, 2012-01--2015-12
（ 10 ） 含氟有机化合物的选择性合成和应用研究, 参与, 国家任务, 2012-01--2016-12
（ 11 ） 一些重要含三氟甲基和多氟苯类氨基酸的立体选择性合成及其在化学生物学中的应用, 负责人, 国家任务, 2010-01--2012-12

（1）C-F键的选择性直接官能团化   第十二届全国有机化学会议   张新刚   2022-09-26
（2）Controllable difluorocarbene transfer via metal    第20届欧洲氟化学会议   张新刚   2022-08-14
（3）Facile Access to Difluoroalkylated Molcules by Nickel-Catalyzed Carbodifunctionalization of Alkenes   2019-08-25
（4）Catalytic Difluoroalkylation Reactions by Controlled Radical and Difluorocarbene Cross-Couplings   2018-12-17
（5）Copper-Catalyzed Highly Stereoselective Fluoroalkylation of Propargylic Sulfonates   2018-11-14
（6）Catalytic Difluoroalkylations and Applications in Late-Stage Fluorination of Bioactive Molecules   2018-11-05
（7）Catalytic Difluoroalkylations by Controlled Radical and Difluorocarbene Cross-Couplings   2018-05-23
（8）可控自由基/二氟卡宾途径的催化氟烷基化   中国化学会第十届全国有机化学学术会议   2017-12-21
（9）Recent Advances in Fluoroalkylations from Fluoroalkyl Halides   2016-09-22
（10）Transition-Metal-Catalyzed C-F Bond Borylation   2016-09-08
（11）Pd/Ni-Catalyzed Difluoroarylation of Organoborons with Difluoroalkyl Bromides and Chlorides   张新刚   2015-08-24
（12）Transition-Metal-Catalyzed Difluoroalkylation of Arenes   张新刚   2014-05-29
（13）Transition-Metal-Catalyzed ortho-Selective C-F Bond Activation of Polyfluoroarenes   张新刚   2013-07-21
（14）Pd-Catalyzed Direct C-H Functionalization of Highly Electron-Deficient Perfluoroarenes   Xingang Zhang   2010-09-09
（15）Pd-Catalyzed Direct Olefination and Benzylation of Highly Electron-Deficient Perfluoroarenes   Xingang Zhang   2010-07-19