071007-遗传学

植物分子遗传学

1989-09--1994-05   美国普渡大学   博士
1984-09--1987-09   遗传所   硕士
1980-09--1984-07   四川大学   学士

   

2012-02~现在, 中国科学院遗传与发育生物学研究所, 研究员
2004-08~2012-01,北京生命科学研究所, 高级研究员、资深研究员
1997-09~2004-08,美国堪萨斯州立大学植物病理系, 助教授、副教授
1994-05~1997-09,普渡大学农学系, 博士后
1989-09~1994-05,美国普渡大学, 博士
1984-09~1987-09,遗传所, 硕士
1980-09~1984-07,四川大学, 学士

植物免疫学
重大慢性传染病
病原微生物与免疫学
信号转导
植物与微生物互作

   

（1） 中国科学院杰出科技成就奖, 院级, 2020

   

（1） 14-3-3 proteins facilitate the activation of MAP kinase cascades by upstream immunity-related kinases, The Plant Cell, 2023, 通讯作者
（2） SHOU4/4L link cell wall cellulose synthesis to pattern-triggered immunity, NEW PHYTOLOGIST, 2023, 第 10 作者
（3） CPR5 positively regulates pattern-triggered immunity via a mediator protein, CPR5 positively regulates pattern-triggered immunity via a mediator protein, JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2023, 通讯作者
（4） New insights from a plant immune receptor may help design of disease resistant crops, New insights from a plant immune receptor may help design of disease resistant crops, SCIENCE CHINA-LIFE SCIENCES, 2023, 通讯作者
（5） PIF3 is phosphorylated by MAPK to modulate plant immunity, NEW PHYTOLOGIST, 2023, 第 9 作者
（6） WeiTsing, a pericycle-expressed ion channel, safeguards the stele to confer clubroot resistance, CELL, 2023, 通讯作者
（7） Two plant NLR proteins confer strain-specific resistance conditioned by an effector from Pseudomonas syringae pv. actinidiae, JOURNAL OF GENETICS AND GENOMICS, 2022, 通讯作者
（8） From plant immunity to crop disease resistance, JOURNAL OF GENETICS AND GENOMICS, 2022, 通讯作者
（9） A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases, Cell Host Microbe, 2022, 通讯作者
（10） The cytosolic thiol peroxidase PRXIIB is an intracellular sensor for H2O2 that regulates plant immunity through a redox relay, Nature Plants, 2022, 通讯作者
（11） The origin and evolution of a plant resistosome, PLANT CELL, 2022, 通讯作者
（12） Regulation of Cell Death and Signaling by Pore-Forming Resistosomes, ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 59, 2021, 2021, 通讯作者
（13） The ZAR1 resistosome is a calcium-permeable channel triggering plant immune signaling, CELL, 2021, 通讯作者
（14） An Arabidopsis Secondary Metabolite Directly Targets Expression of the Bacterial Type III Secretion System to Inhibit Bacterial Virulence, CELL HOST & MICROBE, 2020, 通讯作者
（15） Plant Immunity: Danger Perception and Signaling, CELL, 2020, 通讯作者
（16） Bacterial Effectors Induce Oligomerization of Immune Receptor ZAR1 In Vivo, Bacterial Effectors Induce Oligomerization of Immune Receptor ZAR1 In Vivo, MOLECULARPLANT, 2020, 通讯作者
（17） Malate circulation: linking chloroplast metabolism to mitochomdrial ROS, Trends in Plant Science, 2020, 第 1 作者
（18） Regulation of mitochondrial NAD pool via NAD+ transporter 2 is essential for matrix NADH homeostasis and ROS production 8in Arabidopsis, Sci China Life Sci, 2019, 
（19） The secret of fertilization in flowering plants unveiled, SCIENCE BULLETIN, 2018, 通讯作者
（20） Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases, Ligand-triggered de-repression of Arabidopsis heterotrimeric G proteins coupled to immune receptor kinases, CELLRESEARCH, 2018, 通讯作者
（21） Receptor-Like Cytoplasmic Kinases: Central Players in Plant Receptor Kinase-Mediated Signaling, ANNUAL REVIEW OF PLANT BIOLOGY, VOL 69, 2018, 通讯作者
（22） A Regulatory Module Controlling Homeostasis of a Plant Immune Kinase, MOLECULAR CELL, 2018, 通讯作者
（23） Apoplastic ROS signaling in plant immunity, CURRENT OPINION IN PLANT BIOLOGY, 2017, 通讯作者
（24） 厚积薄发：我国植物-微生物互作研究取得突破, China Takes Long Stride in Plant-microbe Interactions Research, 植物学报, 2017, 第 2 作者
（25） MAP Kinase Signaling Pathways: A Hub of Plant-Microbe Interactions, CELL HOST & MICROBE, 2017, 通讯作者
（26） Receptor Kinases in Plant-Pathogen Interactions: More Than Pattern Recognition, PLANT CELL, 2017, 通讯作者
（27） Arabidopsis heterotrimeric G proteins regulate immunity by directly coupling to the FLS2 receptor, ELIFE, 2016, 通讯作者
（28） Activation-Dependent Destruction of a Co-receptor by a Pseudomonas syringae Effector Dampens Plant Immunity, CELL HOST & MICROBE, 2016, 通讯作者
（29） An Arabidopsis Plasma Membrane Proton ATPase Modulates JA Signaling and Is Exploited by the Pseudomonas syringae Effector Protein AvrB for Stomatal Invasion, PLANT CELL, 2015, 通讯作者
（30） The Decoy Substrate of a Pathogen Effector and a Pseudokinase Specify Pathogen-Induced Modified-Self Recognition and Immunity in Plants, CELL HOST & MICROBE, 2015, 第 15 作者
（31） The FLS2-Associated Kinase BIK1 Directly Phosphorylates the NADPH Oxidase RbohD to Control Plant Immunity, CELL HOST & MICROBE, 2014, 通讯作者
（32） Proline Isomerization of the Immune Receptor-Interacting Protein RIN4 by a Cyclophilin Inhibits Effector-Triggered Immunity in Arabidopsis, CELL HOST & MICROBE, 2014, 第 15 作者
（33） BIK1 interacts with PEPRs to mediate ethylene-induced immunity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 第 8 作者
（34） Structural Basis for flg22-Induced Activation of the Arabidopsis FLS2-BAK1 Immune Complex, SCIENCE, 2013, 第 7 作者
（35） Plant–bacterial pathogen interactions mediated by type III effectors, CURRENT OPINION IN PLANT BIOLOGY, 2012, 通讯作者
（36） Chitin-Induced Dimerization Activates a Plant Immune Receptor, SCIENCE, 2012, 第11作者
（37） Phytopathogen Effectors Subverting Host Immunity: Different Foes, Similar Battleground, CELL HOST & MICROBE, 2012, 通讯作者
（38） A Xanthomonas uridine 5 '-monophosphate transferase inhibits plant immune kinases, NATURE, 2012, 通讯作者
（39） The U-Box/ARM E3 Ligase PUB13 Regulates Cell Death, Defense, and Flowering Time in Arabidopsis, PLANT PHYSIOLOGY, 2012, 第11作者
（40） BAK1 Is Not a Target of the Pseudomonas syringae Effector AvrPto, MOLECULAR PLANT-MICROBE INTERACTIONS, 2011, 通讯作者
（41） Role of small RNAs in the interaction between Arabidopsis and Pseudomonas syringae, FRONTIERS IN BIOLOGY, 2011, 第 3 作者
（42） Effector‐triggered innate immunity contributes Arabidopsis resistance to Xanthomonas campestris, MOLECULAR PLANT PATHOLOGY, 2010, 第 3 作者
（43） Pseudomonas syringae Two-Component Response Regulator RhpR Regulates Promoters Carrying an Inverted Repeat Element, MOLECULAR PLANT-MICROBE INTERACTIONS, 2010, 第 5 作者
（44） Plant innate immunity triggered by microbial molecular signatures., Molecular Plant, 2010, 通讯作者
（45） Effector-triggered and PAMP-triggered immunity differentially contribute to basal resistance to Pseudomonas syringae., MPMI, 2010, 通讯作者
（46） Pseudomonas syringae Effector Protein AvrB Perturbs Arabidopsis Hormone Signaling by Activating MAP Kinase 4, CELL HOST & MICROBE, 2010, 通讯作者
（47） Receptor-like Cytoplasmic Kinases Integrate Signaling from Multiple Plant Immune Receptors and Are Targeted by a Pseudomonas syringae Effector, CELL HOST & MICROBE, 2010, 通讯作者
（48） A Pseudomonas syringae ADP-Ribosyltransferase Inhibits Arabidopsis Mitogen-Activated Protein Kinase Kinases, PLANT CELL, 2010, 第 9 作者
（49） ETHYLENE INSENSITIVE3 and ETHYLENE INSENSITIVE3-LIKE1 Repress SALICYLIC ACID INDUCTION DEFICIENT2 Expression to Negatively Regulate Plant Innate Immunity in Arabidopsis, PLANT CELL, 2009, 通讯作者
（50） Plant immunity: a lesson from pathogenic bacterial effector proteins, CELLULAR MICROBIOLOGY, 2009, 通讯作者
（51） 一种基于报告基因体系的拟南芥非寄主抗性突变体的筛选方法, 科学通报, 2008, 第 4 作者

   

（ 1 ） 植物抗病机理研究, 负责人, 国家任务, 2011-01--2013-12
（ 2 ） 植物免疫机制与作物抗病分子设计的重大基础理论, 负责人, 国家任务, 2011-01--2015-12
（ 3 ） 水稻广谱抗病基因的系统筛选和新种质创新, 参与, 国家任务, 2009-01--2011-12
（ 4 ） 植物细胞表面受体的功能和作用机理, 负责人, 国家任务, 2015-01--2019-12
（ 5 ） 植物NLR免疫受体的遗传与生化功能研究, 负责人, 国家任务, 2014-01--2018-12
（ 6 ） 植物活性氧与氧化还原信号, 负责人, 国家任务, 2016-01--2021-12
（ 7 ） 水稻抗病性状形成的分子基础, 参与, 国家任务, 2016-07--2020-12
（ 8 ） 利用病原细菌效应蛋白研究植物胞内免疫信号转导机理, 负责人, 国家任务, 2013-01--2017-12
（ 9 ） 种间信息的识别解码与人工操纵, 负责人, 中国科学院计划, 2014-07--2019-06
（ 10 ） 胞内免疫受体识别解码系统, 负责人, 中国科学院计划, 2014-07--2019-06
（ 11 ） 根系微生物组促进十字花科植物中磷元素的高效利用, 负责人, 国家任务, 2017-12--2020-11
（ 12 ） 植物抗病大分子作用机制和应用, 负责人, 国家任务, 2022-01--2026-12
（ 13 ） 拟南芥抗病小体免疫信号转导机制, 负责人, 国家任务, 2022-01--2026-12