基本信息
李海鹏 男 博导 中国科学院上海营养与健康研究所
电子邮件: lihaipeng@sinh.ac.cn
通信地址: 上海岳阳路320号
邮政编码: 200031
电子邮件: lihaipeng@sinh.ac.cn
通信地址: 上海岳阳路320号
邮政编码: 200031
招生信息
招生专业
0710Z2-计算生物学
招生方向
计算生物学-适应性进化理论及分子机制开发检测算法
教育背景
1996-09--2002-02 中科院昆明动物所 博士1992-09--1996-06 山东大学 学士
工作经历
工作简历
2020-04~现在, 中国科学院上海营养与健康研究所, 研究员2007-09~2020-03,中科院上海生命科学研究院, 研究员2006-09~2007-08,德国科隆大学, 博士后2003-09~2006-08,德国慕尼黑大学, 博士后2002-03~2003-08,美国德克萨斯大学, 博士后1996-09~2002-02,中科院昆明动物所, 博士1992-09~1996-06,山东大学, 学士
社会兼职
2024-01-01-今,Molecular Biology and Evolution 期刊, Associate Editor
2023-12-01-2026-11-30,山东第一医科大学, 访问教授
2023-01-01-今,中国生物信息学会(筹), 常委
2021-01-01-今,Zoological Research 期刊, Editor
2020-01-01-2024-12-31,中国营养学会, 副主任委员
2020-01-01-今,Frontiers in Genetics 期刊, Associate Editor
2020-01-01-今,Frontiers in Ecology and Evolution 期刊, Associate Editor
2023-12-01-2026-11-30,山东第一医科大学, 访问教授
2023-01-01-今,中国生物信息学会(筹), 常委
2021-01-01-今,Zoological Research 期刊, Editor
2020-01-01-2024-12-31,中国营养学会, 副主任委员
2020-01-01-今,Frontiers in Genetics 期刊, Associate Editor
2020-01-01-今,Frontiers in Ecology and Evolution 期刊, Associate Editor
专利与奖励
奖励信息
(1) 中国科学院上海分院2023年度科技创新“十大进展”(基础研究类), 特等奖, 院级, 2024
出版信息
发表论文
(1) Demography as a confounding factor to explain highly diverged loci between cultivated and wild rice, Plant Genetic Resources, 2024, (2) A noncoding A-to-U Kozak site change related to the high transmissibility of Alpha, Delta, and Omicron VOCs, Molecular Biology and Evolution, 2023, (3) Genomic inference of a severe human bottleneck during the Early to Middle Pleistocene transition, Science, 2023, (4) 从进化生物学角度谈为何中国目前需要动态清零而非与新冠病毒共存, 遗传, 2022, (5) Unexpected expression of heat-activated transient receptor potential (TRP) channels in winter torpid bats and cold-activated TRP channels in summer active bats, Zoological Research, 2022, (6) Coronavirus GenBrowser for monitoring the transmission and evolution of SARS-CoV-2, Briefings in Bioinformatics, 2022, (7) Fine human genetic map based on UK10K data set, Human Genetics, 2022, (8) Global cold-chain related SARS-CoV-2 transmission identified by pandemic-scale phylogenomics, Zoological Research, 2022, (9) Genome-wide analysis of pseudogenes reveals HBBP1���s human-specific essentiality in erythropoiesis and implication in ��-thalassemia, Developmental Cell, 2021, 第 12 作者(10) New exon and accelerated evolution of placental gene Nrk occurred in the ancestral lineage of placental mammals, Placenta, 2021, (11) Accelerated evolution of an Lhx2 enhancer shapes mammalian social hierarchies, Cell Research, 2020, (12) Genomic consequences of population decline in critically endangered pangolins and their demographic histories, National Science Review, 2020, (13) Convergent genomic signatures of high-altitude adaptation among domestic mammals, National Science Review, 2020, 第 12 作者(14) Social enhancer PAS1 and Lhx2 determines social hierarchies in amniotes, Chemistry of Life, 2020, (15) eGPS 1.0: comprehensive software for multi-omic and evolutionary analyses, National Science Review, 2019, (16) Population genetics: From classical statistics to supervised learning, Scientia Sinica Vitae, 2019, (17) Evolution of an X-linked miRNA family predominantly expressed in mammalian male germ cells, Mol Biol Evol, 2019, 第 7 作者(18) The origin and population history of the endangered golden snub-nosed monkey (Rhinopithecus roxellana), Mol Biol Evol, 2019, 第 3 作者(19) Selection and environmental adaptation along a path to speciation in the Tibetan frog Nanorana parkeri, Proc Natl Acad Sci U S A, 2018, 第 12 作者(20) Out of southern East Asia of the brown rat revealed by large scale genome sequencing, Mol Biol Evol, 2018, (21) Detecting recent positive selection with a single locus test bi-partitioning the coalescent tree, Genetics, 2018, (22) Genetic variation in glia-neuron signalling modulates ageing rate, Science, 2017, 第 10 作者(23) Rapid evolution of genes involved in learning and energy metabolism for domestication of the laboratory rat, Mol Biol Evol, 2017, 第 10 作者(24) An integrated method for the identification of novel genes related to oral cancer, PLoS One, 2017, (25) A normalization-free and nonparametric method sharpens large-scale transcriptome analysis and reveals common gene alteration patterns in cancers, Theranostics, 2017, 第 12 作者(26) A large number of vertebrates began rapid population decline in the late 19th century, Proc Natl Acad Sci U S A, 2016, 第 1 作者(27) Revisiting the false positive rate in detecting recent positive selection, Quantitative Biology, 2016, (28) Application of the shortest path algorithm for the discovery of breast cancer-related genes, Current Bioinformatics, 2016, (29) The use of gene ontology term and KEGG pathway enrichment for analysis of drug half-life, PloS One, 2016,
科研活动
科研项目
( 1 ) 发展快速极小时间溯祖新方法估计近期和远古群体历史, 负责人, 国家任务, 2023-01--2026-12( 2 ) 病毒基因组未来演化趋势突变预测模型建立与验证, 参与, 国家任务, 2022-11--2025-10
参与会议
(1)Machine learning apporaches in evolutionary genomics 2018-07-08(2)Recent positive selection? Or false positives? 2015-03-24