基本信息

佟卉春 女 硕导 中国科学院微生物研究所
电子邮件: tonghuichun@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号
邮政编码: 100101
电子邮件: tonghuichun@im.ac.cn
通信地址: 北京市朝阳区北辰西路1号院3号
邮政编码: 100101
招生信息
招生专业
071005-微生物学
招生方向
链球菌抗氧胁迫及致病的分子机制
教育背景
2005-03--2005-07 School of Dentistry, University of California, Los angeles 访问学习2000-08--2003-07 北京大学医学部 博士1995-08--1998-07 中国医科大学 硕士1988-08--1993-07 中国医科大学 本科
工作经历
工作简历
2009-03~2010-03,School of Dentistry, University of Florida, 访问学者2007-05~现在, 中国科学院微生物研究所, 副研究员2005-03~2005-07,School of Dentistry, University of California, Los angeles, 访问学习2003-08~2007-05,中国科学院微生物研究所, 助理研究员2000-08~2003-07,北京大学医学部, 博士1995-08~1998-07,中国医科大学, 硕士1988-08~1993-07,中国医科大学, 本科
教授课程
微生物学实验技术
出版信息
发表论文
(1) A 3' UTR-derived small RNA represses pneumolysin synthesis and facilitates pneumococcal brain invasion, COMMUNICATIONS BIOLOGY, 2024, 第 7 作者 通讯作者(2) Pn-AqpC-Mediated Fermentation Pattern Coordination with the Two-Component System 07 Regulates Host N-Glycan Degradation of Streptococcus pneumoniae, MICROBIOLOGY SPECTRUM, 2022, 第 8 作者 通讯作者(3) A Novel Aquaporin Subfamily Imports Oxygen and Contributes to Pneumococcal Virulence by Controlling the Production and Release of Virulence Factors, MBIO, 2021, 第 2 作者 通讯作者(4) RNase Z Oxidative Degradation Impedes tRNA Maturation and is Involved in Streptococcal Translation Regulation in Response to Oxidative Stress, MICROBIOLOGY SPECTRUM, 2021, 第 2 作者 通讯作者(5) Redox-Regulated Adaptation of Streptococcus oligofermentans to Hydrogen Peroxide Stress, MSYSTEMS, 2020, 第 1 作者 通讯作者(6) Redox-Regulated Adaptation of Streptococcus oligofermentans to Hydrogen Peroxide Stress, MSYSTEMS, 2020, 第 1 作者(7) A Streptococcus aquaporin acts as peroxiporin for efflux of cellular hydrogen peroxide and alleviation of oxidative stress, JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 第 1 作者 通讯作者(8) Prokaryotic Aquaporins, CELLS, 2019, 第 1 作者 通讯作者(9) The carbon catabolite repressor CcpA mediates optimal competence development in Streptococcus oligofermentans through post-transcriptional regulation, MOLECULAR MICROBIOLOGY, 2019, 第 7 作者 通讯作者(10) Molecular Insights into Hydrogen Peroxide-sensing Mechanism of the Metalloregulator MntR in Controlling Bacterial Resistance to Oxidative Stresses, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 第 5 作者 通讯作者(11) Streptococcus oligofermentans Inhibits Streptococcus mutans in Biofilms at Both Neutral pH and Cariogenic Conditions, PLOS ONE, 2015, 第 3 作者(12) PerR-Regulated Manganese Ion Uptake Contributes to Oxidative Stress Defense in an Oral Streptococcus, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2014, 第 2 作者 通讯作者(13) Complete Genome Sequence of an Oral Commensal, Streptococcus oligofermentans Strain AS 1.3089, GENOME ANNOUNCEMENTS, 2013, 第 1 作者(14) Function of the Pyruvate Oxidase-Lactate Oxidase Cascade in Interspecies Competition between Streptococcus oligofermentans and Streptococcus mutans, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2012, 第 2 作者 通讯作者(15) Role of Operon aao So -mutT in Antioxidant Defense in Streptococcus oligofermentans, PLOS ONE, 2012, 第 3 作者(16) Role of Operon aao-mutT in Antioxidant Defense in Streptococcus oligofermentans, PLoS One, 2012, 第 1 作者 通讯作者(17) CcpA-Dependent Carbohydrate Catabolite Repression Regulates Galactose Metabolism in Streptococcus oligofermentans, JOURNAL OF BACTERIOLOGY, 2012, 第 2 作者(18) The EIIABman PTS permease regulates carbohydrate catabolite repression in Streptococcus gordonii, Appl Environ Microbiol, 2011, 第 1 作者(19) The EIIAB(Man) Phosphotransferase System Permease Regulates Carbohydrate Catabolite Repression in Streptococcus gordonii, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2011, 第 1 作者(20) A Preliminary Study of Biological Characteristics of Streptococcus oligofermentans in Oral Microecology, CARIES RESEARCH, 2010, (21) Dpr蛋白在寡发酵链球菌抗过氧化氢中的作用, Role of Dpr in hydrogen peroxide tolerance of Streptococcus oligofermentans, 微生物学报, 2009, 第 2 作者(22) SO-LAAO, a Novel l -Amino Acid Oxidase That Enables Streptococcus oligofermentans To Outcompete Streptococcus mutans by Generating H 2 O 2 from Peptone ��� ���, JOURNAL OF BACTERIOLOGY, 2008, 第 1 作者(23) SO-LAAO, a novel L-amino acid oxidase that enables Streptococcus oligofermentans to outcompete Streptococcus mutans by generation H2O2 from peptone, J Bacteriol, 2008, 第 1 作者(24) 寡发酵链球菌分子标识鉴定方法的建立, Development of an identification method for Streptococcus oligofermentans: a new species of oral streptococci with molecular markers, 中华口腔医学杂志, 2007, 第 2 作者(25) Streptococcus oligofermentans inhibits streptococcus mutans through conversion of lactic acid into inhibitory h2o2: a possible counteroffensive strategy for interspecies competition, MOLECULAR MICROBIOLOGY, 2007, 第 1 作者(26) 一株口腔链球菌新种-寡发酵链球菌产过氧化氢特性的研究, Characterization of hydrogen peroxide production by a novel oral streptococci,S. oligofermentans isolated from human oral cavity, 微生物学报, 2006, 第 2 作者(27) Pediococcus ethanolidurans sp nov., isolated from the walls of a distilled-spirit-fermenting cellar, INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 2006, 第 3 作者(28) Establishing a genetic system for ecological studies of Streptococcus oligofermentans, FEMS MICROBIOLOGY LETTERS, 2006, 第 1 作者(29) Molecular Insights into Hydrogen Peroxide-sensing Mechanism of the Metalloregulator MntR in Controlling Bacterial Resistance to Oxidative Stresses *, THE JOURNAL OF BIOLOGICAL CHEMISTRY, 第 5 作者
科研活动
科研项目
( 1 ) 水圈碳氮硫元素循环的功能微生物及其代谢途径和机制, 参与, 国家任务, 2023-01--2024-12( 2 ) 肺炎链球菌水通道蛋白的生理功能及其介导毒力的分子机制, 负责人, 国家任务, 2019-01--2023-12( 3 ) 肺炎链球菌水通道蛋白的生理功能及其介导毒力的分子机制, 负责人, 国家任务, 2019-01--2023-12( 4 ) 副乾酪乳桿菌V0151生理、生化特性及动物毒性的影响, 参与, 境内委托项目, 2014-02--2014-08( 5 ) 寡发酵链球菌抗氧胁迫的分子机制, 负责人, 国家任务, 2014-01--2017-12
参与会议
(1)链球菌抗氧胁迫的分子机制 2019年全国微生物学年会 2019-10-12