基本信息
邓菲  女  博导  中国科学院武汉病毒研究所
电子邮件: df@wh.iov.cn
通信地址: 湖北省武汉市小洪山中区44号
邮政编码: 430071

招生信息

   
招生专业
071005-微生物学
100103-病原生物学
招生方向
病毒学
基础医学

工作经历

   
工作简历
2013-08~现在, 中国科学院武汉病毒研究所, 研究员
2007-09~现在, 中国科学院武汉病毒研究所, 副研究员
2003-07~现在, 中国科学院武汉病毒研究所, 助理研究员

专利与奖励

   
奖励信息
(1) 湖北省自然科学一等奖, 一等奖, 省级, 2011
专利成果
( 1 ) 一种杆状病毒基因组的合成方法及其在重组杆状病毒构建中的应用, 2019, 第 3 作者, 专利号: CN106754896B

( 2 ) 一种抗HSV的糖蛋白gD的单克隆抗体以及产生该抗体的杂交瘤细胞, 2019, 第 6 作者, 专利号: CN105925537B

( 3 ) 一种用于检测地中海贫血突变体的引物组及试剂盒, 2019, 第 5 作者, 专利号: CN109609628A

( 4 ) 一种可进行生物安全操作的冷冻干燥装置, 2018, 第 2 作者, 专利号: CN207659421U

( 5 ) 一种可进行生物安全操作的冷冻干燥装置, 2018, 第 2 作者, 专利号: CN107629943A

( 6 ) 用于杆状病毒滴度测定的重组细胞系及其测定方法, 2014, 第 1 作者, 专利号: CN103571795A

( 7 ) 表达gp64基因的新型基因工程重组病毒的构建方法, 2012, 第 4 作者, 专利号: CN102382803A

( 8 ) 用于提高杆状病毒对哺乳动物细胞转导效率的方法, 2011, 第 5 作者, 专利号: CN102199629A

( 9 ) 用液相芯片检测虫媒或接触传播病原的引物和探针及方法, 2011, 第 3 作者, 专利号: CN102181532A

( 10 ) 用液相芯片检测呼吸道传染病病原的引物和探针及方法, 2011, 第 3 作者, 专利号: CN102181576A

( 11 ) 用于检测乙型肝炎病毒耐药突变位点的引物及方法, 2011, 第 3 作者, 专利号: CN102181575A

( 12 ) 一种抑制乙型肝炎病毒的天然提取物及其主要活性成份, 2007, 第 3 作者, 专利号: CN101028382

( 13 ) 杆状病毒的gp64和p35基因的联合应用, 2005, 第 3 作者, 专利号: CN1654658

出版信息

   
发表论文
(1) Establishment of a Reverse Genetic System of Severe Fever with Thrombocytopenia Syndrome Virus Based on a C4 Strain, VIROLOGICA SINICA, 2021, 第 3 作者
(2) SARS-CoV-2 infection induces sustained humoral immune responses in convalescent patients following symptomatic COVID-19, NATURE COMMUNICATIONS, 2021, 通讯作者
(3) Immune evasion of SARS-CoV-2 from interferon antiviral system, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 第 4 作者
(4) Differential Cell Line Susceptibility to Crimean-Congo Hemorrhagic Fever Virus, FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2021, 通讯作者
(5) Identification, Isolation, and Characterization of an Ectromelia Virus New Strain from an Experimental Mouse, VIROLOGICA SINICA, 2021, 第 10 作者
(6) SARS-CoV-2 interacts with platelets and megakaryocytes via ACE2-independent mechanism, JOURNAL OF HEMATOLOGY & ONCOLOGY, 2021, 通讯作者
(7) Metagenomic Profiling of Viruses Associated with Rhipicephalus microplus Ticks in Yunnan Province, China, VIROLOGICA SINICA, 2021, 通讯作者
(8) SARS-CoV-2 Rapidly Adapts in Aged BALB/c Mice and Induces Typical Pneumonia, JOURNAL OF VIROLOGY, 2021, 第 4 作者
(9) SARS-CoV-2 cell tropism and multiorgan infection, CELL DISCOVERY, 2021, 第 10 作者
(10) Immunological detection of serum antibodies in pediatric medical workers exposed to varying levels of SARS-CoV-2, JOURNAL OF INFECTION, 2021, 通讯作者
(11) Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes, VIROLOGICA SINICA, 2021, 通讯作者
(12) Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice, EBIOMEDICINE, 2021, 第 9 作者
(13) Ozone Water Is an Effective Disinfectant for SARS-CoV-2, VIROLOGICA SINICA, 2021, 
(14) Clinicopathologic Features of COVID-19: A Case Report and Value of Forensic Autopsy in Studying SARS-CoV-2 Infection, AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY, 2021, 第 8 作者
(15) Systematic analysis of nuclear localization of Autographa californica multiple nucleopolyhedrovirus proteins, JOURNAL OF GENERAL VIROLOGY, 2021, 第 4 作者
(16) Fine mapping epitope on Glycoprotein-Gn from Severe Fever with Thrombocytopenia Syndrome Virus, PLOS ONE, 2021, 通讯作者
(17) 古尔图病毒重组截短糖蛋白基因的表达及抗体的制备, Expression and antibody preparation of recombinant truncated glycoprotein of Guertu virus, 中华微生物学和免疫学杂志, 2020, 第 6 作者
(18) SARS-CoV-2 nsp1: Bioinformatics, Potential Structural and Functional Features, and Implications for Drug/Vaccine Designs, FRONTIERS IN MICROBIOLOGY, 2020, 第 4 作者
(19) Meta-Transcriptome Profiling of Novel Invasive Pest Spodoptera frugiperda in Yunnan,China, Meta-Transcriptome Profiling of Novel Invasive Pest Spodoptera frugiperda in Yunnan, China, VIROLOGICA SINICA, 2020, 通讯作者
(20) 一种可能起源于蝙蝠的新型冠状病毒有关的肺炎暴发, A pneumonia outbreak associated with a new coronavirus of probable bat origin, Nature, 2020, 第 20 作者
(21) Structural characterization and antiviral activity of two fucoidans from the brown algae Sargassum henslowianum, CARBOHYDRATE POLYMERS, 2020, 通讯作者
(22) The Nonstructural Protein of Guertu Virus Disrupts Host Defenses by Blocking Antiviral Interferon Induction and Action, ACS INFECTIOUS DISEASES, 2020, 通讯作者
(23) Combinatorial Minigenome Systems for Emerging Banyangviruses Reveal Viral Reassortment Potential and Importance of a Protruding Nucleotide in Genome "Panhandle" for Promoter Activity and Reassortment, FRONTIERS IN MICROBIOLOGY, 2020, 第 3 作者
(24) Dhori病毒核蛋白基因的重组表达及其抗体制备, Recombinant expression of Dhor virus nucleoprotein gene and its antibody preparation, 生物技术, 2020, 第 7 作者
(25) Crimean-Congo Hemorrhagic Fever Virus in Humans and Livestock, Pakistan, 2015–2017, EMERGING INFECTIOUS DISEASES, 2020, 第 18 作者
(26) Guertu virus NSs protein disrupts host defense by blocking antiviral interferon induction and action, ACS infectious diseases, 2020, 第 6 作者
(27) Host AAA plus ATPase TER94 Plays Critical Roles in Building the Baculovirus Viral Replication Factory and Virion Morphogenesis, JOURNAL OF VIROLOGY, 2020, 第 5 作者
(28) Structure of severe fever with thrombocytopenia syndrome virus L protein elucidates the mechanisms of viral transcription initiation, NATURE MICROBIOLOGY, 2020, 通讯作者
(29) Genome Analysis of Dasineura jujubifolia Toursvirus 2, A Novel Ascovirus, VIROLOGICA SINICA, 2020, 第 5 作者
(30) Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly, PLOS PATHOGENS, 2020, 第 3 作者
(31) A cell-based large-scale screening of natural compounds for inhibitors of SARS-CoV-2, A cell-based large-scale screening of natural compounds for inhibitors of SARS-CoV-2, SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2020, 第 6 作者
(32) SARS-CoV-2 N protein antagonizes type I interferon signaling by suppressing phosphorylation and nuclear translocation of STAT1 and STAT2, CELL DISCOVERY, 2020, 第 8 作者
(33) Immunological detection of serum antibodies in pediatric medical workers exposed to varying levels of SARS-CoV-2, Journal of Infection, 2020, 通讯作者
(34) Per Os Infectivity Factor 5 Identified as a Substrate of P33 in the Baculoviral Disulfide Bond Formation Pathway, JOURNAL OF VIROLOGY, 2020, 第 6 作者
(35) Co-infection of SARS-CoV-2 and Influenza virus in Early Stage of the COVID-19 Epidemic in Wuhan, China, JOURNAL OF INFECTION, 2020, 通讯作者
(36) Comparative Antiviral Efficacy of Viral Protease Inhibitors against the Novel SARS-CoV-2 In Vitro, VIROLOGICA SINICA, 2020, 第 21 作者
(37) Serologic Evidence of Severe Fever with Thrombocytopenia Syndrome Virus and Related Viruses in Pakistan, EMERGING INFECTIOUS DISEASES, 2020, 第 24 作者
(38) Genomic and transcriptional analyses of novel parvoviruses identified from dead peafowl, VIROLOGY, 2020, 第 10 作者
(39) Transcriptome analysis of the innate immune system of Hyalomma asiaticum, JOURNAL OF INVERTEBRATE PATHOLOGY, 2020, 第 6 作者
(40) Distribution of Airborne SARS-CoV-2 and possible aerosol transmission in Wuhan hospitals, China, NATIONAL SCIENCE REVIEW, 2020, 第 8 作者
(41) A RIG-I–like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination, JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 通讯作者
(42) Detection and characterization of a novel hepacivirus in long-tailed ground squirrels (Spermophilus undulatus) in China, ARCHIVES OF VIROLOGY, 2019, 通讯作者
(43) Interferon-gamma-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1, FRONTIERS IN IMMUNOLOGY, 2019, 第 9 作者
(44) Host factor heat-shock protein 90 contributes to baculovirus budded virus morphogenesis via facilitating nuclear actin polymerization, VIROLOGY, 2019, 第 7 作者
(45) Functional Characterization of the Group I Alphabaculovirus Specific Gene ac73, Functional Characterization of the Group I Alphabaculovirus Specific Gene ac73, VIROLOGICA SINICA, 2019, 第 5 作者
(46) Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection, JOURNAL OF VIROLOGY, 2019, 第 7 作者
(47) Baculovirus Per Os Infectivity Factor Complex: Components and Assembly, JOURNAL OF VIROLOGY, 2019, 第 13 作者
(48) N-6-methyladenosine modification and METTL3 modulate enterovirus 71 replication, NUCLEIC ACIDS RESEARCH, 2019, 通讯作者
(49) First case of laboratory-confirmed severe fever with thrombocytopenia syndrome disease revealed the risk of SFTSV infection in Xinjiang, China, EMERGING MICROBES & INFECTIONS, 2019, 第11作者
(50) Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1, JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 第 2 作者
(51) Zika virus circumvents host innate immunity by targeting the adaptor proteins MAVS and MITA, FASEB JOURNAL, 2019, 第 9 作者
(52) Fine mapping epitope on glycoprotein Gc from Crimean-Congo hemorrhagic fever virus, COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 2019, 第 9 作者
(53) Single-particle tracking reveals the sequential entry process of the bunyavirus severe fever with thrombocytopenia syndrome virus, SMALL, 2019, 第 5 作者
(54) Mito-docking: A Novel In Vivo Method to Detect Protein-Protein Interactions, SMALL METHODS, 2019, 第 3 作者
(55) Identification and genomic sequence analysis of a new Spodoptera exigua multiple nucleopolyhedrovirus, SeMNPV-QD, isolated from Qingdao, China, JOURNAL OF INVERTEBRATE PATHOLOGY, 2019, 第 5 作者
(56) 微生物与细胞资源的保存与发掘利用, Preservation and Utilization of Microorganism and Cell Resources, 中国科学院院刊, 2019, 第 3 作者
(57) Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1, The Journal of Biological Chemistry, 2019, 第 2 作者
(58) Baculovirus ODV-E66 degrades larval peritrophic membrane to facilitate baculovirus oral infection, VIROLOGY, 2019, 第 10 作者
(59) Genome Analysis of a Novel Clade II.b Alphabaculovirus Obtained from Artaxa digramma, Viruses, 2019, 第 5 作者
(60) Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1, Frontiers in Immunology, 2019, 
(61) A dengue fever predicting model based on Baidu search index data and climate data in South China, PLoS ONE, 2019, 第 5 作者
(62) The cysteine-rich region of a baculovirus VP91 protein contributes to the morphogenesis of occlusion bodies, VIROLOGY, 2019, 第 7 作者
(63) The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes, JOURNAL OF VIROLOGY, 2019, 第 4 作者
(64) Taxonomy of the order Bunyavirales : update 2019, ARCHIVES OF VIROLOGY, 2019, 
(65) Fine epitope mapping of glycoprotein Gn in Guertu virus, PLoS ONE, 2019, 通讯作者
(66) Improving Baculovirus Transduction of Mammalian Cells by Incorporation of Thogotovirus Glycoproteins, VIROLOGICA SINICA, 2019, 第 3 作者
(67) The group i alphabaculovirus-specific protein, ac5, is a novel component of the occlusion body but is not associated with odvs or the pif complex, JOURNAL OF GENERAL VIROLOGY, 2018, 第 5 作者
(68) Fine mapping epitope on glycoprotein-gn from crimean-congo hemorrhagic fever virus, COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 2018, 第 8 作者
(69) The first laboratory-confirmed sfts case from the xinjiang uygur autonomous region importing to hainan international tourism island, ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2018, 其他(合作组作者)
(70) Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice, VIROLOGICA SINICA, 2018, 通讯作者
(71) Isolation,Characterization,and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province,China, Isolation, Characterization, and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province, China, VIROLOGICA SINICA, 2018, 通讯作者
(72) HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability, VIROLOGICA SINICA, 2018, 第 7 作者
(73) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, 中国病毒学:英文版, 2018, 其他(合作组作者)
(74) Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, VIROLOGICA SINICA, 2018, 第 5 作者
(75) Three Conserved Regions in Baculovirus Sulfhydryl Oxidase P33 Are Critical for Enzymatic Activity and Function., Journal of Virology, 2018, 
(76) Establishment of baculovirus-expressed vlps induced syncytial formation assay for flavivirus antiviral screening, VIRUSES-BASEL, 2018, 通讯作者
(77) The Functional Oligomeric State of Tegument Protein GP41 Is Essential for Baculovirus Budded Virion and Occlusion-Derived Virion Assembly, JOURNAL OF VIROLOGY, 2018, 第 4 作者
(78) Tick-Borne Viruses, VIROLOGICA SINICA, 2018, 通讯作者
(79) HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, 中国病毒学:英文版, 2018, 第 7 作者
(80) Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China, Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China, 中国病毒学:英文版, 2018, 第11作者
(81) Mapping of B-cell epitopes on the N-terminal and C-terminal segment of nucleocapsid protein from Crimean-Congo hemorrhagic fever virus, PLOS ONE, 2018, 通讯作者
(82) The functional oligomeric state of tegument protein GP41 is essential for baculovirus BV and ODV assembly., J Virol., 2018, 第 1 作者
(83) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, VIROLOGICA SINICA, 2018, 其他(合作组作者)
(84) A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen, EMERGING MICROBES & INFECTIONS, 2018, 通讯作者
(85) Isolation,Characterization,and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province,China, Isolation,Characterization,and Phylogenetic Analysis of Two New Crimean-Congo Hemorrhagic Fever Virus Strains from the Northern Region of Xinjiang Province,China, 中国病毒学:英文版, 2018, 第 13 作者
(86) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group Ⅰ of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group Ⅰ of Alphabaculovirus, 中国病毒学:英文版, 2018, 其他(合作组作者)
(87) 布尼亚病毒目新分类概述, A review and novel classification of Bunyavirales, 生物多样性, 2018, 第 7 作者
(88) Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, 中国病毒学:英文版, 2018, 第 5 作者
(89) Establishment of Baculovirus-Expressed VLPs Induced Syncytial Formation Assay for Flavivirus Antiviral Screening, Viruses, 2018, 
(90) Genome analysis of a novel Group I alphabaculovirus obtained from Oxyplax ochracea, PLOS ONE, 2018, 第 8 作者
(91) Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China, Prevalence and Phylogenetic Analysis of Crimean-Congo Hemorrhagic Fever Virus in Ticks from Different Ecosystems in Xinjiang,China, VIROLOGICA SINICA, 2018, 通讯作者
(92) Migration, recombination, and reassortment are involved in the evolution of severe fever with thrombocytopenia syndrome bunyavirus., Infect Genet Evol., 2017, 
(93) The roles of ebolavirus glycoproteins in viral pathogenesis, VIROLOGICA SINICA, 2017, 第 2 作者
(94) A cluster of symptomatic and asymptomatic infections of severe fever with thrombocytopenia syndrome caused by person-to-person transmission, AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2017, 其他(合作组作者)
(95) Construction and rescue of a functional synthetic baculovirus, ACS SYNTHETIC BIOLOGY, 2017, 通讯作者
(96) A new strain of Crimean-Congo hemorrhagic fever virus isolated from Xinjiang, China, VIROLOGICA SINICA, 2017, 通讯作者
(97) Migration, recombination, and reassortment are involved in the evolution of severe fever with thrombocytopenia syndrome bunyavirus, INFECTION GENETICS AND EVOLUTION, 2017, 第 9 作者
(98) Antigenicity of severe fever with thrombocytopenia syndrome virus nucleocapsid protein and its potential application in the virus serodiagnosis, VIROLOGICA SINICA, 2017, 通讯作者
(99) Ebola virus mucin-like glycoprotein (Emuc) induces remarkable acute inflammation and tissue injury: evidence for Emuc pathogenicity in vivo., Protein Cell., 2017, 
(100) Extensive evolution analysis of the global chikungunya virus strains revealed the origination of CHIKV epidemics in Pakistan in 2016, VIROLOGICA SINICA, 2017, 通讯作者
(101) Quantitative Proteomic Analysis of Mosquito C6/36 Cells Reveals Host Proteins Involved in Zika Virus Infection, JOURNAL OF VIROLOGY, 2017, 第 7 作者
(102) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 第 4 作者
(103) Detection, isolation, and characterization of chikungunya viruses associated with the Pakistan outbreak of 2016–2017, VIROLOGICA SINICA, 2017, 第 9 作者
(104) The roles of ebolavirus glycoproteins in viral pathogenesis., Virol Sin., 2017, 
(105) Three Conserved Regions in Baculovirus Sulfhydryl Oxidase P33 Are Critical for Enzymatic Activity and Function, JOURNAL OF VIROLOGY, 2017, 第 5 作者
(106) Isolation, characterization, and phylogenic analysis of three new severe fever with thrombocytopenia syndrome bunyavirus strains derived from Hubei Province, China, VIROLOGICA SINICA, 2017, 通讯作者
(107) A novel glycoprotein D-specific monoclonal antibody neutralizes herpes simplex virus, ANTIVIRAL RESEARCH, 2017, 第 8 作者
(108) Spatial Analysis of Severe Fever with Thrombocytopenia Syndrome Virus in China Using a Geographically Weighted Logistic Regression Model, INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2016, 第 2 作者
(109) Molecular basis for the formation of ribonucleoprotein complex of crimean-congo hemorrhagic fever virus, JOURNAL OF STRUCTURAL BIOLOGY, 2016, 通讯作者
(110) Mutational and functional analysis of N-linked glycosylation of envelope fusion protein F of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2016, 通讯作者
(111) Virus like particle-based vaccines against emerging infectious disease viruses, VIROLOGICA SINICA, 2016, 通讯作者
(112) Characterization of the viral fibroblast growth factor homolog of Helicoverpa armigera single nucleopolyhedrovirus, VIROLOGICA SINICA, 2016, 第 6 作者
(113) Genome Sequencing and Analysis of Catopsilia pomona nucleopolyhedrovirus: A Distinct Species in Group I Alphabaculovirus, PLOS ONE, 2016, 第 9 作者
(114) 滇西横断山区家畜体表蜱类调查及鉴定, Tick species and genetic variants analysis of tick gene in Hengduan Mountains, west Yunnan Province, China, 中国人兽共患病学报, 2016, 第 4 作者
(115) A 3-year follow-up study of the seroprevalence of antibodies to avian influenza A H5, H6, H7 and H10 viruses among the general population of Wuhan, China, JOURNAL OF CLINICAL VIROLOGY, 2016, 通讯作者
(116) Phylogenetic analysis revealed the central roles of two African countries in the evolution and worldwide spread of Zika virus, VIROLOGICA SINICA, 2016, 通讯作者
(117) Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation, JOURNAL OF VIROLOGY, 2016, 第11作者
(118) Pathologic Studies of Fatal Encephalomyelitis in Children Caused by Enterovirus 71, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2016, 第 10 作者
(119) 乙型脑炎病毒样颗粒疫苗的制备及其免疫保护效率的初步评价, Generation of Japanese Encephalitis Virus-likeParticle Vaccine and Preliminary Evaluation of Its Protective Efficiency, 病毒学报, 2016, 第 8 作者
(120) The Host Specificities of Baculovirus per os Infectivity Factors, PLOS ONE, 2016, 第 6 作者
(121) 新疆出血热病毒多表位基因的原核表达及间接ELISA方法的建立, Prokaryotic expression of a multi-epitope gene of Xinjiang hemorrhagic fever virus and development of an indirect ELISA for virus detection, 中华微生物学和免疫学杂志, 2016, 第 5 作者
(122) P33 of helicoverpa armigera single nucleocapsid nucleopolyhedrovirus is a functional homolog of acp33, VIROLOGICA SINICA, 2016, 第 5 作者
(123) Characterization of two monoclonal antibodies, 38f10 and 44d11, against the major envelope fusion protein of helicoverpa armigera nucleopolyhedrovirus, VIROLOGICA SINICA, 2016, 第 4 作者
(124) Genome sequencing and analysis of a granulovirus isolated from the Asiatic rice leafroller, Cnaphalocrocis medinalis, VIROLOGICA SINICA, 2015, 第 5 作者
(125) Glycoprotein E of the Japanese encephalitis virus forms virus-like particles and induces syncytia when expressed by a baculovirus, JOURNAL OF GENERAL VIROLOGY, 2015, 第 6 作者
(126) Disruption of Type I Interferon Signaling by the Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Virus via the Hijacking of STAT2 and STAT1 into Inclusion Bodies, JOURNAL OF VIROLOGY, 2015, 第 6 作者
(127) 杆状病毒病毒粒子结构与口服感染和系统感染的关系, 生命科学, 2015, 
(128) The FP25K Acts as a Negative Factor for the Infectivity of AcMNPV Budded Virus, PLOS ONE, 2015, 第 6 作者
(129) Resistant mutations and quasispecies complexity of hepatitis B virus during telbivudine treatment, JOURNAL OF GENERAL VIROLOGY, 2015, 第 7 作者
(130) Identification of the epitopes of monoclonal antibodies against P74 of Helicoverpa armigera nucleopolyhedrovirus (vol 28, pg 360, 2013), VIROLOGICA SINICA, 2015, 第 5 作者
(131) An in vitro recombination-based reverse genetic system for rapid mutagenesis of structural genes of the Japanese encephalitis virus, VIROLOGICA SINICA, 2015, 通讯作者
(132) The FP25K Acts as a Negative Factor for the Infectivity of AcMNPV Budded Virus, PLOS ONE, 2015, 第 6 作者
(133) The Complete Genome of a New Betabaculovirus from Clostera anastomosis, PLOS ONE, 2015, 第 10 作者
(134) Genome Sequence and Analysis of Buzura suppressaria Nucleopolyhedrovirus: A Group II Alphabaculovirus, PLOS ONE, 2014, 第 9 作者
(135) Identification and functional analysis of inter-subunit disulfide bonds of the F protein of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2014, 第 4 作者
(136) Viral suppression of innate immunity via spatial isolation of TBK1/IKK epsilon from mitochondrial antiviral platform, JOURNAL OF MOLECULAR CELL BIOLOGY, 2014, 第 7 作者
(137) Serological study of antibodies to influenza A viruses among general population in Wuhan city China, JOURNAL OF CLINICAL VIROLOGY, 2014, 第 8 作者
(138) The ha72 Core Gene of Baculovirus Is Essential for Budded Virus Production and Occlusion-Derived Virus Embedding, and Amino Acid K22 Plays an Important Role in Its Function, JOURNAL OF VIROLOGY, 2014, 第 3 作者
(139) Genomic Sequencing and Analysis of Sucra jujuba Nucleopolyhedrovirus, PLOS ONE, 2014, 通讯作者
(140) Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antivirai platform, Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antivirai platform, 分子细胞生物学报:英文版, 2014, 第 7 作者
(141) Fine Epitope Mapping of the Central Immunodominant Region of Nucleoprotein from Crimean-Congo Hemorrhagic Fever Virus (CCHFV), PLOS ONE, 2014, 第 4 作者
(142) Unraveling the Entry Mechanism of Baculoviruses and Its Evolutionary Implications, JOURNAL OF VIROLOGY, 2014, 第 5 作者
(143) Identification and functional analysis of inter-subunit disulfide bonds of F protein of HearNPV., 2014, 第 1 作者
(144) Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform, Journal of Molecular Cell Biology, 2014, 第 7 作者
(145) Cyanophage and Algal Virus, Cyanophage and Algal Virus, 中国病毒学:英文版, 2013, 第 1 作者
(146) Reassortment and migration analysis of Crimean-Congo haemorrhagic fever virus, JOURNAL OF GENERAL VIROLOGY, 2013, 第 2 作者
(147) Comparative Proteomics Reveal Fundamental Structural and Functional Differences between the Two Progeny Phenotypes of a Baculovirus, JOURNAL OF VIROLOGY, 2013, 
(148) Characterization and Genomic Analysis of a Plaque Purified Strain of Cyanophage PP, Characterization and Genomic Analysis of a Plaque Purified Strain of Cyanophage PP, 中国病毒学:英文版, 2013, 第 5 作者
(149) The ha72 core gene of baculovirus is essential for budded virus production and Occlusion-Derived Virus embedding, and amino acid K22 plays an important role in its function., 2013, 第 1 作者
(150) Freshwater Cyanophages, Freshwater Cyanophages, 中国病毒学:英文版, 2013, 
(151) The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation, PROTEIN & CELL, 2013, 第 9 作者
(152) Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus, Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus, 中国病毒学:英文版, 2013, 第 5 作者
(153) Comparative Proteomics Reveal Fundamental Structural and Functional Differences between the Two Progeny Phenotypes of a Baculovirus, JOURNAL OF VIROLOGY, 2013, 第 3 作者
(154) Betabaculovirus F proteins showed different efficiencies when rescuing the infectivity of gp64-null Autographa californica nucleopolyhedrovirus, VIROLOGY, 2013, 第 4 作者
(155) Characterization and Genomic Analysis of a Plaque Purified Strain of Cyanophage PP, Characterization and Genomic Analysis of a Plaque Purified Strain of Cyanophage PP, 中国病毒学:英文版, 2013, 
(156) Freshwater Cyanophages, Freshwater Cyanophages, 中国病毒学:英文版, 2013, 第 3 作者
(157) Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2012, 第 5 作者
(158) Betabaculovirus F Proteins Showed Different Efficiency when Rescuing the, 2012, 
(159) Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro, JOURNAL OF GENERAL VIROLOGY, 2012, 第 6 作者
(160) Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2012, 第 5 作者
(161) Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 8 作者
(162) Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro, JOURNAL OF GENERAL VIROLOGY, 2012, 第 6 作者
(163) ORF85 of HearNPV encodes the per os infectivity factor 4 (PIF4) and is essential for the formation of the PIF complex, VIROLOGY, 2012, 第 3 作者
(164) Genetic Modification of Baculovirus Expression Vectors, Genetic Modification of Baculovirus Expression Vectors, 中国病毒学:英文版, 2012, 
(165) Genetic Modification of Baculovirus Expression Vectors, Genetic Modification of Baculovirus Expression Vectors, 中国病毒学:英文版, 2012, 第 4 作者
(166) ORF85 of HearNPV encodes the per os infectivity factor 4 (PIF4) and is essential for the formation of the PIF complex.2012., 2012, 
(167) Analysis of the structural proteins from the Musca domestica hytrosavirus with an emphasis on the major envelope protein., Journal of Invertebrate Pathology., 2012, 第 1 作者
(168) Developments of Subunit and VLP Vaccines Against Influenza A Virus, Developments of Subunit and VLP Vaccines Against Influenza A Virus, 中国病毒学:英文版, 2012, 第 4 作者
(169) Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, ha100, affects oral infectivity in vivo but not virus replication in vitro, JOURNAL OF GENERAL VIROLOGY, 2011, 通讯作者
(170) Production and characterization of monoclonal antibodies against the hemagglutinin of h5n1 and antigenic investigation of avian influenza h5n1 viruses isolated from china, CANADIAN JOURNAL OF MICROBIOLOGY, 2011, 第 5 作者
(171) Production of CCHF virus-like particle by a baculovirus-insect cell expression system, Virologica Sinica, 2011, 第 3 作者
(172) Identification of protein-protein interactions of the occlusion-derived virus-associated proteins of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2010, 
(173) Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions ▿, JOURNAL OF VIROLOGY, 2010, 第 2 作者
(174) Partial Functional Rescue of HearNPV Infectivity by Substitution of F Protein with GP64 from AcMNPV., Journal of Virology, 2010, 
(175) AcMNPV efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH., Journal of Virology, 2010, 
(176) Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, 中国病毒学:英文版, 2010, 第 8 作者
(177) Partial Functional Rescue of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus Infectivity by Replacement of F Protein with GP64 from Autographa californica Multicapsid Nucleopolyhedrovirus ▿, JOURNAL OF VIROLOGY, 2010, 第 5 作者
(178) Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, Virologica Sinica, 2010, 第 8 作者
(179) Autographa californica Multicapsid Nucleopolyhedrovirus Efficiently Infects Sf9 Cells and Transduces Mammalian Cells via Direct Fusion with the Plasma Membrane at Low pH ▿, JOURNAL OF VIROLOGY, 2010, 第 4 作者
(180) Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions ▿, JOURNAL OF VIROLOGY, 2010, 第 2 作者
(181) Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, 中国病毒学:英文版, 2009, 第 5 作者
(182) Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, 中国病毒学:英文版, 2009, 
(183) Angiotensin-converting enzyme 2 (ace2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus, JOURNAL OF GENERAL VIROLOGY, 2009, 通讯作者
(184) Variants of open reading frame bm126 in wild-type bombyx mori nucleopolyhedrovirus isolates exhibit functional differences, JOURNAL OF GENERAL VIROLOGY, 2009, 第 4 作者
(185) The F protein of Helicoverpa armigera single nucleopolyhedrovirus can be substituted functionally with its homologue from Spodoptera exigua multiple nuclopolyhedrovirus., 2009, 第 1 作者
(186) Virion Proteomics of Large DNA Viruses, Virion Proteomics of Large DNA Viruses, 中国病毒学:英文版, 2009, 第 4 作者
(187) Virion Proteomics of Large DNA Viruses, Virion Proteomics of Large DNA Viruses, 中国病毒学:英文版, 2009, 
(188) Evidence of a major role of GP64 in group I alphabaculovirus evolution, VIRUS RESEARCH, 2009, 第 2 作者
(189) An Improved Culture System for Virus Isolation and Detection, An Improved Culture System for Virus Isolation and Detection, 中国病毒学:英文版, 2008, 第 6 作者
(190) Open reading frame bm21 of bombyx mori nucleopolyhedrovirus is not essential for virus replication in vitro, but its deletion extends the median survival time of infected larvae, JOURNAL OF GENERAL VIROLOGY, 2008, 第 3 作者
(191) The F-Like Protein Ac23 Enhances the Infectivity of the Budded Virus of gp64 -Null Autographa californica Multinucleocapsid Nucleopolyhedrovirus Pseudotyped with Baculovirus Envelope Fusion Protein F ▿ †, JOURNAL OF VIROLOGY, 2008, 第 4 作者
(192) Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro, ANTIVIRAL RESEARCH, 2008, 第 3 作者
(193) An extensive analysis on the global codon usage pattern of baculoviruses, ARCHIVES OF VIROLOGY, 2008, 第 2 作者
(194) The f protein of helicoverpa armigera single nucleopolyhedrovirus can be substituted functionally with its homologue from spodoptera exigua multiple nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2008, 第 4 作者
(195) A Functional F Analogue of Autographa californica Nucleopolyhedrovirus GP64 from the Agrotis segetum Granulovirus ▿, JOURNAL OF VIROLOGY, 2008, 第 4 作者
(196) An Improved Culture System for Virus Isolation and Detection, An Improved Culture System for Virus Isolation and Detection, 中国病毒学:英文版, 2008, 
(197) Mutagenesis and nuclear magnetic resonance analyses of the fusion peptide of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus F protein, JOURNAL OF VIROLOGY, 2008, 第 5 作者
(198) HearNPV在生长对数期与平台期宿主细胞中的复制差异分析, Comparative Study of the Replication Difference of HearNPV in Infect Exponential and Stationary Host Cells, 病毒学报, 2007, 第 5 作者
(199) Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, 中国病毒学, 2007, 第 4 作者
(200) The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions, VIROLOGY, 2007, 第 2 作者
(201) Deletion of a helicoverpa armigera nucleopolyhedrovirus gene encoding a virion structural protein (orf 107) increases the budded virion titre and reduces in vivo infectivity, JOURNAL OF GENERAL VIROLOGY, 2007, 第 9 作者
(202) The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions, VIROLOGY, 2007, 第 2 作者
(203) Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, 中国病毒学, 2007, 
(204) High-level production of a functional recombinant hepatitis b virus polymerase in insect cells with a baculovirus expression system, JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2007, 第 3 作者
(205) 乙型肝炎病毒多聚酶基因在重组杆状病毒系统中的表达, Expression of hepatitis B virus polymerase in recombinant baculovirus, 胃肠病学和肝病学杂志, 2007, 第 3 作者
(206) 缺失p10基因的重组棉铃虫病毒导致多角体囊膜包装不完整, Deletion of p10 From the Genome of HaSNPV Results in a Faulty Polyhedral Envelope, 中国病毒学, 2006, 第 2 作者
(207) HaSNPV的9个基因的转录谱分析, The Transcription Profiles of Nine HaSNPV Genes, 中国病毒学, 2006, 第 2 作者
(208) 液相芯片MASA技术用于儿童呼吸道感染病原学研究, Etiological Study of Respiratory Tract Infections in Children by Using Multi-analyte Suspension Array Technology, 中国病毒学, 2005, 第 2 作者
(209) HzAm1细胞rpL13基因的序列分析及病毒感染对其转录水平的影响, Sequence Analysis of RpL13 Gene from HzAml Cells and Effect of HaSNPV Infection on the Transcription of RpL13, 中国病毒学, 2005, 第 2 作者
(210) 表达GP64的重组HaSNPV的构建研究, Construction of a Recombinant HaSNPV Expressing GP64, 中国病毒学, 2005, 第 3 作者
(211) 含外源类蜗牛毒素基因的AcMNPV的虫体感染性研究, Study of Foreign Baculoviral ctl Gene by Overexpression Using AcMNPV Bacmid System in vivo, 中国病毒学, 2004, 第 4 作者
(212) 感染HaSNPV棉铃虫幼虫的组织病理和免疫组化研究, pathogenic and Immunohistochemical Studies of the HaSNPV Infected Helicoverpa armigera Larvae, 中国病毒学, 2003, 第 1 作者
(213) 棉铃虫单核衣壳核多角体病毒几丁质酶基因的克隆与表达, Molecular Cloning and Expression of the Chitinase Gene from Helicoverpa, 中国病毒学, 2002, 第 3 作者
(214) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction, The Journal of Biological Chemistry, 

科研活动

   
科研项目
( 1 ) 昆虫病毒感染关键步骤的分子机理研究; , 参与, 国家任务, 2009-01--2013-12
( 2 ) Ⅱ型包膜病毒的入侵机制 , 参与, 国家任务, 2010-01--2014-12
( 3 ) 棉铃虫病毒的结构蛋白HA44的结构与功能及真核定位机理研究, 负责人, 国家任务, 2007-11--2010-12
( 4 ) 中国境内重要生物安全Ⅲ-Ⅳ级病原的流行病学调查, 负责人, 国家任务, 2007-08--2010-12
( 5 ) 杆状病毒-昆虫细胞生物反应器的建设与优化, 负责人, 中国科学院计划, 2011-01--2013-12
( 6 ) 杆状病毒和昆虫细胞间的相互作用, 参与, 国家任务, 2008-01--2012-12
( 7 ) 我国重要自然宿主及媒介昆虫的病毒病原调查, 负责人, 国家任务, 2013-05--2018-12
( 8 ) 生物遗传资源库, 负责人, 中国科学院计划, 2018-06--2018-12
( 9 ) 重要烈性病毒防控关键技术及产品研发, 参与, 中国科学院计划, 2016-01--2018-12
( 10 ) 病毒遗传资源库保藏能力建设, 负责人, 中国科学院计划, 2017-01--2018-12
( 11 ) 重要RNA病毒的细胞受体研究, 负责人, 研究所自选, 2017-01--2018-12
( 12 ) 欧洲病毒资源库走向全球, 参与, 国家任务, 2016-12--2019-11
( 13 ) 生防微生物环境适应性与持效性机制, 负责人, 国家任务, 2017-07--2020-12
( 14 ) 湖北省发热伴血小板减少综合症病毒传播途径 和致病机理的研究, 负责人, 地方任务, 2019-01--2020-12
( 15 ) 湖北省发热伴血小板减少综合征病毒SFTSV遗传进化与病症相关性研究, 负责人, 研究所自选, 2018-01--2019-12
参与会议
(1)ncorporation of GP64 into Helicoverpa armigera NPV enhances virus infectivity both in vivo and in vitro.   2012国际无脊椎病理和微生物防治会议暨45届无脊椎病理年会   Shu Shen, Yinyin Gan, Manli Wang, Zhihong Hu, Hualin Wang and Fei Deng.    2012-08-05
(2)HA44 is an Essential Gene for Helicoverpa Armigera Nucleopolyhedrovirus Replication and its Coiled-Coil Domain is Functional Important   第44届无脊椎动物病理学年会   邓菲   2011-08-07
(3)Global View and the phenotype model of the Occlusion-Derived Virus of Helicoverpa armigera Nucleopolyhedrovirus   第43届无脊椎动物病理学年会   邓菲   2010-07-09
(4)Identification of Proteins Associated with Autographa californica Nucleopolyhedrovirus Budded Virions   国际无脊椎病理学会第42届年会   邓菲   2009-08-16