致力于仿生超分子化学的分子组装和纳米结构体系设计。尤其是基于生物分子磷脂，肽与蛋白的仿生分子组装和物理化学机理的研究，通过组装构建“人工细胞”。以模拟生物体结构和功能为基础，在分子水平上构筑具有特殊功能的超分子组装体。重点研究旋转马达蛋白ATP合酶与线性马达蛋白Kinesin的优化重组，从多维度模拟细胞器结构与功能；探索ATP合酶在调控叶绿体的光合磷酸化和线粒体的氧化磷酸化过程中的能量合成机制，实现功能增强；研究寡肽分子尤其是苯丙氨酸的组装与解组装，结构转变调控及其光电性质的研究；通过模板组装技术构建系列功能化纳米结构体系；双光子共聚焦和超分辨荧光成像在组装体系中的应用研究。

   

070304-物理化学（含：化学物理）
080502-材料学

          胶体界面
          药物化学
          生物化学

      1982年至1989年在吉林大学化学系读本科及硕士。 
      1992年德国美因兹大学物理化学研究所联合培养博士生。 
      1992年12月于吉林大学化学系获博士学位。 
      1993年至1996年先后在希腊国家研究与工程基地、德国马普胶体与界面研究所从事博士后研究。
　　1996年中国科学院原感光化学研究所研究员、博士生导师。
　　1999年中科院化学所研究员、博士生导师。
　　1997 年入选中国科学院“****”； 1998年获国家人事部“优秀回国留学人员奖”； 1999年获国家自然科学基金委“国家杰出青年基金”资助； 2000年获香港求是基金会“杰出青年学者奖”； 2001年被评为“中国科学院第六届十大杰出青年”；2004年获中国分析测试协会科学技术二等奖（CAIA奖）；2004年选入“新世纪百千万人才工程国家级人选”。 现担任国际学术期刊“Colloids & Surfaces A”主编，国际综述学术期刊“Current Opinion in Colloid & Interface Science”专题编辑，Chem、JCIS和Soft Matter等期刊的顾问编委，化学学报编委。担任国际胶体与界面学会常务理事，亚洲胶体与界面学会常务理事，中国化学会理事，首批会士，中国化学会胶体与界面专业委员会主任。

   

[1] 李峻柏, 贾怡, 高凡, 王培芝. 一种铁配位多巴胺基纳米材料及其制备方法与应用. CN: CN116514877A, 2023-08-01.

[2] 李峻柏, 熊珠珠, 贾怡. 一种基于多糖/多巴胺复合膜的仿生漆酶体系及其制备方法与应用. CN: CN113694964A, 2021-11-26.

[3] 李峻柏, 孙楠, 贾怡. 一种多巴胺/磷酸钙杂化微米花的制备方法及应用. CN: CN113521307A, 2021-10-22.

[4] 李自若, 贾怡, 李峻柏. 一种臭氧气体排放还原检测与自动化控制系统. CN: CN215339713U, 2021-12-28.

[5] 李自若, 贾怡, 李峻柏. 用于新冠病毒样品检测前处理的消毒系统. CN: CN215308687U, 2021-12-28.

[6] 李自若, 贾怡, 李峻柏. 一种臭氧浓度恒定检测与控制的自动化操作系统. CN: CN216208872U, 2022-04-05.

[7] 李自若, 贾怡, 李峻柏. 用于冷冻食物链外包装的消毒设备. CN: CN215308686U, 2021-12-28.

[8] 李峻柏, 薛慧敏, 费进波. 一种制备肽基晶体材料的方法. CN: CN111892642A, 2020-11-06.

[9] 李峻柏, 薛慧敏, 费进波. 一种制备肽基晶体材料的方法. CN: CN111892642B, 2023-03-31.

[10] 李峻柏, 王晨蕾, 费进波. 一种基于二肽的仿生漆酶的制备方法及应用. CN: CN111185229B, 2021-03-26.

[11] 李峻柏, 崔巍, 赵洁, 李伟. 一种蛋白质纳米颗粒的制备方法. CN: CN111035618B, 2021-08-10.

[12] 李峻柏, 王克青, 赵洁, 付梅芳. 一种功能化磷脂制备纳米单颗粒的方法及该纳米单颗粒的检测. CN: CN110108624A, 2019-08-09.

[13] 李峻柏, 李现宝, 费进波. 一种二肽气凝胶及其制备方法与应用. CN: CN109821484A, 2019-05-31.

[14] 李峻柏, 赵洁. 一种光敏药物贴剂及制备方法. CN: CN109731101A, 2019-05-10.

[15] 李峻柏, 王克青, 王晨蕾, 崔巍, 许有前. 一种阳离子二肽与金杂化微球及其制备方法与应用. CN: CN109596690A, 2019-04-09.

[16] 李峻柏, 孙冰冰. 一种一维二肽单晶及其在毛细管内的自组装制备方法和解组装方法. CN: CN107974713A, 2018-05-01.

[17] 李峻柏, 袁婷婷, 费进波, 许有前. 一种pH响应性肽基水凝胶及其制备方法与应用. CN: CN106890135B, 2020-04-07.

[18] 李峻柏, 袁婷婷, 费进波, 许有前. 一种pH响应性肽基水凝胶及其制备方法与应用. CN: CN106890135A, 2017-06-27.

[19] 李峻柏, 赵洁. 一种对微弱光敏感的光敏药物及其制备方法. CN: CN106668859A, 2017-05-17.

[20] 李峻柏, 费进波, 张鹤, 秦晨晨. 一种具有pH响应的可快速释放客体分子的纳米载体及其制备方法与应用. CN: CN106242995A, 2016-12-21.

[21] 李峻柏, 秦晨晨, 费进波, 崔巍. 一种光敏药物纳米颗粒及其制备方法与应用. CN: CN105999268A, 2016-10-12.

[22] 李峻柏, 秦晨晨, 费进波, 王安河. 一种金纳米材料及其制备方法和应用. CN: CN104873975A, 2015-09-02.

[23] 李峻柏, 秦晨晨, 费进波, 王安河. 一种核壳型金纳米材料及其制备方法和应用. CN: CN104800846A, 2015-07-29.

[24] 李峻柏, 李姣, 冯熙云, 蔡鹏. 一种表面组装有PSII的二氧化钛纳米管修饰电极及其制备方法与应用. CN: CN104821405A, 2015-08-05.

[25] 李峻柏, 贾怡, 冯熙云, 董伟光, 李洁龄. 一种葡萄糖响应的微管-驱动蛋白运输体系及其制备方法. CN: CN104152433A, 2014-11-19.

[26] 李峻柏, 冯熙云, 蔡鹏, 贾怡, 费进波, 董伟光, 李洁龄. 一种光可控ATP生物合成体系及其制备方法. CN: CN104059954A, 2014-09-24.

[27] 李峻柏, 李洁龄, 贾怡, 董伟光, 冯熙云. 一种微纳米管及其制备方法与应用. CN: CN104016299A, 2014-09-03.

[28] 李峻柏, 贾怡, 李洁龄, 冯熙云, 董伟光. 自供能量的微管-驱动蛋白运输体系及其制备方法. CN: CN104020298A, 2014-09-03.

[29] 李峻柏, 张鹤, 崔岳. 一种自发荧光的纳米球及其制备方法与应用. CN: CN104031636A, 2014-09-10.

[30] 李峻柏, 崔巍. 一种具有协同抗肿瘤效应的生物兼容纳米药物复合载体、药物及其制备方法. CN: CN102921014A, 2013-02-13.

[31] 李峻柏, 李红. 蜂窝状多孔结构二氧化钛涂层种植体材料及其制备方法. CN: CN102943256A, 2013-02-27.

[32] 李峻柏, 高靓, 费进波. 自发荧光微胶囊及其制备方法与应用. CN: CN102727464A, 2012-10-17.

[33] 李峻柏, 鲁闻生. 一种制备金属-PDMS复合材料的方法. CN: CN102627784A, 2012-08-08.

[34] 李峻柏, 杜翠玲, 赵洁. 一种海藻酸钙微胶囊及其制备方法与应用. CN: CN102626399A, 2012-08-08.

[35] 李峻柏, 费进波. 铁羟基氧化物和铁氧化物分级纳米结构材料及其制备方法与应用. CN: CN103204547A, 2013-07-17.

[36] 李峻柏, 赵洁. 一种生物自发光的药物载体及其制备方法. CN: CN102379860A, 2012-03-21.

[37] 李峻柏, 贾怡, 崔岳, 费进波, 杨洋. 一种血红蛋白微胶囊血液代用品及其制备方法. CN: CN102871985A, 2013-01-16.

[38] 李峻柏, 杜明春, 崔岳. 生物大分子的水凝胶生物支架及其制备方法. CN: CN102335455A, 2012-02-01.

[39] 李峻柏, 贾怡, 费进波, 崔岳. 一种层层组装的微胶囊及其制备方法. CN: CN102335575A, 2012-02-01.

[40] 李峻柏, 武美霞. 一种光敏药物贴剂及其制备方法. CN: CN102335160A, 2012-02-01.

[41] 李峻柏, 艾素芬. 一种无机多孔纳米管及其制备方法. CN: CN1966396B, 2012-02-01.

[42] 李峻柏, 田莹, 贺强. 层层组装技术构造多组分纳米管. CN: CN1746105A, 2006-03-15.

[43] 李峻柏, 卢刚. 蛋白质和蛋白质/磷脂微胶囊及其制备方法. 中国: CN1511516, 2004-07-14.

[44] 李峻柏, 郑素萍. 粒子模板及粒子组装和转移的方法. 中国: CN1512179, 2004-07-14.

[45] 李峻柏, 贺强, 阿明·格尔卓瑟, 米夏埃尔·格伦策. 具有表面纳米阵列的生物模拟材料及其制备方法. 中国: CN1512181, 2004-07-14.

[46] 李峻柏, 安智华. 一种生物兼容的药物载体及其制备方法. CN: CN100337688C, 2007-09-19.

[47] 李峻柏, 朱海峰. 有序孔聚合物膜及其制备方法. 中国: CN1511874, 2004-07-14.

[48] 李峻柏, 张翼, 胡贝特·莫奇曼, 克劳斯－迪特尔·万特克. 磷脂蛋白质复合膜、胶囊、及其改进的制备方法. 中国: CN1478468, 2004-03-03.

[49] 李峻柏, 卢刚. 一种生物兼容的微胶囊及其制备方法. 中国: CN1476926, 2004-02-25.

[50] 李峻柏, 张翼, 卢刚. 磷脂蛋白质复合膜、胶囊、及其制备方法. 中国: CN1476827, 2004-02-25.

   

[1] Nan Sun, Yi Jia, Shiwei Bai, Yang Yang, Luru Dai, Junbai Li. Spatial mapping and quantitative evaluation of protein corona on PEGylated mesoporous silica particles by super-resolution fluorescence microscopy. JOURNAL OF COLLOID AND INTERFACE SCIENCE. 2024, 第 6 作者  通讯作者  653: 351-358, http://dx.doi.org/10.1016/j.jcis.2023.09.067.
[2] Jie Zhao, Xia Xu, Yang Yang, Junbai Li. Assembled Photosensitizers Applied for Enhanced Photodynamic Therapy. 中国化学会会刊(英文)[J]. 2023, 第 4 作者  通讯作者  5(5): 1043-1060, http://lib.cqvip.com/Qikan/Article/Detail?id=7109829184.
[3] Chengqian Yuan, Qi Li, Ruirui Xing, Junbai Li, Xuehai Yan. Peptide self-assembly through liquid-liquid phase separation. CHEM. 2023, 第 4 作者9(9): 2425-2445, http://dx.doi.org/10.1016/j.chempr.2023.05.009.
[4] Fei, Jinbo, Li, Junbai. Advance in ATP-involved active self-assembled systems. CURRENT OPINION IN COLLOID & INTERFACE SCIENCE. 2023, 第 2 作者  通讯作者  63: http://dx.doi.org/10.1016/j.cocis.2022.101647.
[5] Wu, Aoli, Guo, Yongxian, Li, Xianbao, Li, Qi, Chen, Guixin, Zang, Hengchang, Li, Junbai. Schiff base nanoarchitectonics for supramolecular assembly of dipeptide as drug carriers. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2023, 第 7 作者  通讯作者  630: 161-169, http://dx.doi.org/10.1016/j.jcis.2022.09.122.
[6] 刘鸣华, 李峻柏, 韩布兴. 前言：纪念江龙院士诞辰90周年专刊. 中国科学:化学. 2023, 第 2 作者53(7): 1031-1033, http://lib.cqvip.com/Qikan/Article/Detail?id=7110223829.
[7] Nan Sun, Yi Jia, Shiwei Bai, Qi Li, Luru Dai, Junbai Li. The power of super-resolution microscopy in modern biomedical science. ADVANCES IN COLLOID AND INTERFACE SCIENCE. 2023, 第 6 作者  通讯作者  314: http://dx.doi.org/10.1016/j.cis.2023.102880.
[8] Zibo Li, Fanchen Yu, Xia Xu, Wang, TongHui, Jinbo Fei, Jingcheng Hao, Junbai Li. Photozyme-Catalyzed ATP Generation Based on ATP Synthase-Reconstituted Nanoarchitectonics. J. Am. Chem. Soc.[J]. 2023, 第 7 作者  通讯作者  145(38): 20907-20912, 
[9] Li, Xianbao, Li, Qi, Wu, Aoli, Li, Junbai. CO2 Induces Symmetry Breaking in Layered Dipeptide Crystals. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2023, 第 4 作者  通讯作者  62(1): 
[10] Tonghui Wang, Jinbo Fei, Zhenzhen Dong, Xia Xu, Weiguang Dong, Junbai Li. Enhanced Bioenergy Transformation by Metal-Free Electrozyme-Based Mitochondrion Nanoarchitectonics. 中国化学会会刊(英文)[J]. 2023, 第 6 作者  通讯作者  5(7): 1644-1652, http://lib.cqvip.com/Qikan/Article/Detail?id=7110084710.
[11] Liu, Yilin, Zhao, Jie, Xu, Xia, Xu, Yang, Cui, Wei, Yang, Yang, Li, Junbai. Emodin-Based Nanoarchitectonics with Giant Two-Photon Absorption for Enhanced Photodynamic Therapy. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2023, 第 7 作者  通讯作者  http://dx.doi.org/10.1002/anie.202308019.
[12] Yamei Liu, Ruirui Xing, Junbai Li, Xuehai Yan. Covalently triggered self-assembly of peptide-based nanodrugs for cancer theranostics. ISCIENCE. 2023, 第 3 作者26(1): http://dx.doi.org/10.1016/j.isci.2022.105789.
[13] Zhenzhen Dong, Jinbo Fei, Tonghui Wang, Junbai Li. Long afterglow particle enables spectral and temporal light management to boost photosynthetic efficiency. JOURNAL OF COLLOID AND INTERFACE SCIENCE. 2023, 第 4 作者  通讯作者  638: 76-83, http://dx.doi.org/10.1016/j.jcis.2023.01.084.
[14] Li, Xin, Jian, Honglei, Han, Qingquan, Wang, Anhe, Li, Jieling, Man, Ningyuan, Li, Qi, Bai, Shuo, Li, Junbai. Three-dimensional (3D) bioprinting of medium toughened dipeptide hydrogel scaffolds with Hofmeister effect. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2023, 第 9 作者  通讯作者  639: 1-6, http://dx.doi.org/10.1016/j.jcis.2023.02.033.
[15] CHANG Rui, Zhao, Luyang, Ruirui Xing, Li, Junbai, Xuehai Yan. Functional chromopeptide nanoarchitectonics: molecular design, self-assembly and biological applications. Chem. Soc. Rev[J]. 2023, 第 4 作者  通讯作者  
[16] Yilin Liu, Junbai Li. Self-assembling nanoarchitectonics of size-controllable celastrol nanoparticles for efficient cancer chemotherapy with reduced systemic toxicity. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2023, 第 2 作者  通讯作者  636: 216-222, http://dx.doi.org/10.1016/j.jcis.2022.12.162.
[17] Zhou, Peng, Xing, Ruirui, Li, Qi, Li, Junbai, Yuan, Chengqian, Yan, Xuehai. Steering phase-separated droplets to control fibrillar network evolution of supramolecular peptide hydrogels. MATTER[J]. 2023, 第 4 作者6(6): 1945-1963, http://dx.doi.org/10.1016/j.matt.2023.03.029.
[18] Aoli Wu, Yongxian Guo, Meiqi Li, Qin Li, Hengchang Zang, Junbai Li. Tunable Chirality of Self-Assembled Dipeptide Mediated by Bipyridine Derivative. Angew. Chem. Int. Ed.[J]. 2023, 第 6 作者  通讯作者  
[19] Qi Li, Mingjun Xuan, Anhe Wang, Yi Jia, Shuo Bai, Xuehai Yan, Junbai Li. Biogenic sensors based on dipeptide assemblies. MATTER. 2022, 第 7 作者5(11): 3643-3658, http://dx.doi.org/10.1016/j.matt.2022.08.023.
[20] Gao, Fan, Xiong, Zhuzhu, Jia, Yi, Li, Hong, Li, Junbai. Cu-boosted one-pot nanoarchitectonics for synthesis of polydopamine membranes as reusable laccase mimic. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2022, 第 5 作者  通讯作者  628: 935-942, http://dx.doi.org/10.1016/j.jcis.2022.07.167.
[21] Li, Hong, Xiong, Zhuzhu, Jia, Yi, Gao, Fan, Wang, Chenlei, Li, Qi, Li, Junbai. Flexible Recyclable Cellulose Paper Templated Cu-Doped Polydopamine Membranes with Dual Enzyme-Like Activity. SMALL[J]. 2022, 第 7 作者  通讯作者  18(34): http://dx.doi.org/10.1002/smll.202202405.
[22] Tonghui Wang, Jinbo Fei, Xia Xu, Zhenzhen Dong, Weiguang Dong, Junbai Li. Enhanced Bioenergy Transformation by Metal-free Electrozyme Based Mitochondrion Nanoarchitectonics. CCS CHEMISTRY[J]. 2022, 第 6 作者
[23] Zibo Li, Xia Xu, Fanchen Yu, Jinbo Fei, Qiang Li, Mingdong Dong, Junbai Li. Oriented Nanoarchitectonics of Bacteriorhodopsin for Enhancement of ATPGeneration of FoF1-ATPase Based Assembly System. ANGEWCHEMINTED[J]. 2022, 第 7 作者  通讯作者  
[24] Jie Zhao, Yuguang Yang, Xia Xu, Hongyan Li, Jinbo Fei, Yilin Liu, Xiaoming Zhang, Junbai Li. Super Light-Sensitive Photosensitizer Nanoparticles for Improved Photodynamic Therapy against Solid Tumors. Angew. Chem. Int. Ed.[J]. 2022, 第 8 作者61: 
[25] Xianbao Li, Qi Li, Aoli Wu, Junbai Li. CO2 Induces Symmetry Breaking in Layered Dipeptide Crystals. Angew. Chem. Int. Ed.[J]. 2022, 第 4 作者  通讯作者  
[26] Dong, Zhenzhen, Fei, Jinbo, Wang, Tonghui, Xu, Xia, Dong, Weiguang, Li, Junbai. Black Phosphorus Nanosheets Enhance Photophosphorylation by Positive Feedback. CHINESE JOURNAL OF CHEMISTRY[J]. 2022, 第 6 作者  通讯作者  40(8): 939-945, http://dx.doi.org/10.1002/cjoc.202100735.
[27] Yi Jia, Xuehai Yan, 李峻柏. Super Schiff Base Mediated Dipeptide Assembly toward Nanoarchitectonics. Angew. Chem. Int. Ed.[J]. 2022, 第 3 作者  通讯作者  
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[29] Sun, Nan, Jia, Yi, Wang, Chenlei, Xia, Jiarui, Cao, Hongqian, Dai, Luru, Li, Chunmei, Zhang, Xiaoming, Li, Junbai. Monitoring the distribution of internalized silica nanoparticles inside cells via direct stochastic optical reconstruction microscopy. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2022, 第 9 作者  通讯作者  615: 248-255, http://dx.doi.org/10.1016/j.jcis.2022.01.196.
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[162] Ariga, Katsuhiko, Li, Junbai, Fei, Jinbo, Ji, Qingmin, Hill, Jonathan P. Nanoarchitectonics for Dynamic Functional Materials from Atomic-/Molecular-Level Manipulation to Macroscopic Action. ADVANCED MATERIALS[J]. 2016, 第 2 作者  通讯作者  28(6): 1251-1286, http://dx.doi.org/10.1002/adma.201502545.
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      理论物理所
      哈尔滨工业大学
      山东大学
      浙江大学

高靓  硕士研究生  070304-物理化学  80032-化学研究所

李红  博士研究生  070304-物理化学  80032-化学研究所

贾怡  博士研究生  070304-物理化学  80032-化学研究所

崔巍  硕士研究生  070304-物理化学  80032-化学研究所

赵洁  博士研究生  070304-物理化学  80032-化学研究所

苏颖  博士研究生  070304-物理化学  80032-化学研究所

杜明春  博士研究生  070304-物理化学  80032-化学研究所