基本信息
胡新天 男 博导 中国科学院昆明动物研究所
电子邮件: xthu@mail.kiz.ac.cn
通信地址: 中国科学院昆明动物研究所
邮政编码: 650223
电子邮件: xthu@mail.kiz.ac.cn
通信地址: 中国科学院昆明动物研究所
邮政编码: 650223
招生信息
招生专业
071006-神经生物学
招生方向
中枢系统疾病猕猴模型的建立和机理研究猕猴认知功能相关神经回路的研究光与健康
教育背景
1994-09--2000-08 Princeton University,USA 博士学位1988-07--1991-07 中国科学院昆明动物研究所 硕士学位1984-09--1988-06 中国科学技术大学 学士学位
工作经历
工作简历
2015-01~现在, 中国科学院脑卓越中心, 骨干2005-12~现在, 中国科学院昆明动物研究所, 研究员2000-09~2005-12,美国贝勒医学院, 博士后1994-09~2000-08,Princeton University,USA, 博士学位1991-07~1994-08,中国科学院昆明动物研究所, 研究实习员1988-07~1991-07,中国科学院昆明动物研究所, 硕士学位1984-09~1988-06,中国科学技术大学, 学士学位
专利与奖励
奖励信息
(1) 中科院核心骨干研究员, 院级, 2022(2) 云南省引进海外高层次人才, , 省级, 2011(3) 云南省有突出贡献优秀专业技术人才奖, 三等奖, 省级, 2008(4) 中国科学院“引进国外杰出人才”称号, , 院级, 2007(5) 恒河猴工作记忆的儿茶酚胺受体机制研究, 一等奖, 省级, 2001(6) NIH 博士后fellowship, , 研究所(学校), 2001(7) 普林斯顿大学心理系优秀助教奖, , 研究所(学校), 1998
专利成果
( 1 ) 一种可抑制眼轴过度增长的新型灯具, 2020, 第 1 作者, 专利号: CN211780301U( 2 ) 一种可抑制眼轴过度增长的新型光源及其模拟方法、灯具, 2020, 第 1 作者, 专利号: CN111140774A( 3 ) 植入式巩膜电极, 2019, 第 1 作者, 专利号: CN208610842U( 4 ) 触屏多功能非人灵长类动物认知功能测试笼, 2019, 第 8 作者, 专利号: CN105532490B( 5 ) 动物眼科检查立体定位仪, 2018, 第 1 作者, 专利号: CN108209856A( 6 ) 一种照明光源对猕猴属动物眼轴发育的对比研究方法, 2018, 第 1 作者, 专利号: CN107981837A( 7 ) 猕猴触屏认知训练装置, 2017, 第 7 作者, 专利号: CN206481796U( 8 ) 一种活体荧光信号的记录装置, 2017, 第 7 作者, 专利号: CN206330889U( 9 ) 一种活体荧光信号的拍照装置, 2017, 第 7 作者, 专利号: CN206330888U( 10 ) 一种活体荧光信号的检测装置, 2017, 第 7 作者, 专利号: CN206330887U( 11 ) 一种活体荧光信号的拍照装置及方法, 2017, 第 7 作者, 专利号: CN106821311A( 12 ) 一种活体荧光信号的检测装置及方法, 2017, 第 7 作者, 专利号: CN106691386A( 13 ) 一种活体荧光信号的记录装置及方法, 2017, 第 7 作者, 专利号: CN106706585A( 14 ) 猕猴矫正触屏的训练方法及训练装置, 2017, 第 7 作者, 专利号: CN106614383A( 15 ) 用于非人灵长类动物认知功能触屏测试笼的给水装置, 2016, 第 8 作者, 专利号: CN205357588U( 16 ) 触屏多功能非人灵长类动物认知功能测试方法, 2016, 第 8 作者, 专利号: CN105534483A( 17 ) 触屏多功能非人灵长类动物认知功能测试笼, 2016, 第 8 作者, 专利号: CN105532490A( 18 ) 数字化多通道电刺激伪迹消除记录装置, 2014, 第 3 作者, 专利号: CN203506713U( 19 ) 检测非人灵长类动物惊吓反射的猴椅, 2014, 第 4 作者, 专利号: CN203493622U( 20 ) 用于磁共振的大动物头部固定装置, 2014, 第 3 作者, 专利号: CN203493638U( 21 ) 全脑切片排刀, 2014, 第 3 作者, 专利号: CN203401507U( 22 ) 侧脑室MPP + 给药建立非人灵长类帕金森病动物模型的方法, 2013, 第 3 作者, 专利号: CN103340859A( 23 ) 双向微电极推进器及微电极, 2013, 第 2 作者, 专利号: CN203195686U( 24 ) 树鼩全脑切片模具, 2013, 第 2 作者, 专利号: CN203198001U( 25 ) 用于大动物脑立体定位仪的耳杆高度可调耳杆座, 2013, 第 2 作者, 专利号: CN203195793U( 26 ) 建立老年痴呆症动物模型的方法、专用药液及给药装置, 2013, 第 2 作者, 专利号: CN103284980A( 27 ) 微电极推进器, 2012, 第 2 作者, 专利号: CN202619649U( 28 ) 脑部电损毁电极, 2012, 第 2 作者, 专利号: CN202619842U( 29 ) 脑微量组织取样器, 2012, 第 2 作者, 专利号: CN102652682A( 30 ) 深部硬脑膜穿孔装置, 2012, 第 5 作者, 专利号: CN102631234A( 31 ) 用低剂量MPTP建立雄性猕猴慢性帕金森病模型的方法, 2010, 第 1 作者, 专利号: CN101779609A( 32 ) 社会地位诱发的抑郁症动物模型建立方法, 2010, 第 1 作者, 专利号: CN101773096A( 33 ) 模拟老年痴呆病变的非人灵长类动物模型的建立方法, 2010, 第 1 作者, 专利号: CN101755709A( 34 ) 多功能可调猴椅, 2008, 第 3 作者, 专利号: CN101249026A( 35 ) 一种电刺激噪声消除仪, 2008, 第 1 作者, 专利号: CN101138495A( 36 ) N-取代基-4-取代苯基-5-烷基-5-取代苄基吡咯烷酮-2,其中间体,其合成方其法及应用, 1998, 第 6 作者, 专利号: CN1040747C
出版信息
发表论文
(1) 原位敲除猕猴视网膜RHO基因构建非人灵长类视网膜色素变性模型, Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, 科学通报:英文版, 2021, 第 17 作者(2) Depletion of giant ANK2 in monkeys causes drastic brain volume loss, CELL DISCOVERY, 2021, 第 14 作者 通讯作者(3) Generation of nonhuman primate retinitis pigmentosa model by in situ knockout of RHO in rhesus macaque retina, SCIENCE BULLETIN, 2021, 第 17 作者 通讯作者(4) Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease, Biological implications and limitations of a cynomolgus monkey with naturally occurring Parkinson's disease, ZOOLOGICAL RESEARCH, 2021, 第 3 作者 通讯作者(5) In vivo Neuroregeneration to Treat Ischemic Stroke Through NeuroD1 AAV-Based Gene Therapy in Adult Non-human Primates, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2020, 第 10 作者 通讯作者(6) 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates (vol 20, 258, 2019), GENOME BIOLOGY, 2020, 第 9 作者 通讯作者(7) CircGRIA1 shows an age-related increase in male macaque brain and regulates synaptic plasticity and synaptogenesis, NATURE COMMUNICATIONS, 2020, 第 11 作者(8) Chronic Glucocorticoid Exposure Induces Depression-Like Phenotype in Rhesus Macaque (Macaca Mulatta), FRONTIERS IN NEUROSCIENCE, 2019, 第 11 作者 通讯作者(9) 547 transcriptomes from 44 brain areas reveal features of the aging brain in non-human primates, GENOME BIOLOGY, 2019, 第 9 作者 通讯作者(10) Behavioral screening tools for identifying autism in macaques: existing and promising tests, BRAIN RESEARCH BULLETIN, 2019, 第 4 作者 通讯作者(11) Direct sunlight exposure reduces hair cortisol levels in rhesus monkeys ( Macaca mulatta ), ZOOLOGICAL RESEARCH, 2019, 第 9 作者 通讯作者(12) Alterations of Gray Matter Volume and White Matter Integrity in Maternal Deprivation Monkeys, NEUROSCIENCE, 2018, 第 11 作者 通讯作者(13) Phosphorylated alpha-Synuclein Accumulations and Lewy Body-like Pathology Distributed in Parkinson's Disease-Related Brain Areas of Aged Rhesus Monkeys Treated with MPTP, NEUROSCIENCE, 2018, 第 11 作者 通讯作者(14) Annotation and functional clustering of circRNA expression in rhesus macaque brain during aging, CELL DISCOVERY, 2018, 第 9 作者(15) Alzheimer's Disease-like Pathologies and Cognitive Impairments Induced by Formaldehyde in Non-Human Primates, CURRENT ALZHEIMER RESEARCH, 2018, 第 13 作者 通讯作者(16) Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells, FRONTIERS IN NEUROSCIENCE, 2017, 第 10 作者(17) Sr 2+ has low efficiency in regulating spontaneous release at the Calyx of Held synapses, SYNAPSE, 2017, 第 6 作者 通讯作者(18) Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, CELL, 2017, 第 34 作者(19) Iron oxide nanoclusters for T-1 magnetic resonance imaging of non-human primates, NATURE BIOMEDICAL ENGINEERING, 2017, 第 13 作者(20) Kisspeptin-10 treatment generated specific GnRH expression in cells differentiated from rhesus monkey derived Lyon NSCs, NEUROSCIENCE, 2017, 第 2 作者(21) comparativestudyofthetransfectionefficiencyofcommonlyusedviralvectorsinrhesusmonkeymacacamulattabrains, ZOOLOGICAL RESEARCH, 2017, 第 13 作者 通讯作者(22) The RNA editome of Macaca mulatta and functional characterization of RNA editing in mitochondria, SCIENCE BULLETIN, 2017, 第 10 作者(23) Modeling Rett Syndrome Using TALEN-Edited MECP2 Mutant Cynomolgus Monkeys, CELL, 2017, 第 34 作者(24) 非人灵长类模型*, 中国科学院院刊, 2016, 第 1 作者(25) Prolonged secretion of cortisol as a possible mechanism underlying stress and depressive behaviour., SCIENTIFIC REPORTS, 2016, 第 8 作者 通讯作者(26) Social correlates of the dominance rank and long-term cortisol levels in adolescent and adult male rhesus macaques (Macaca mulatta), SCIENTIFIC REPORTS, 2016, 第 15 作者(27) A Robust Single Primate Neuroepithelial Cell Clonal Expansion System for Neural Tube Development and Disease Studies, STEM CELL REPORTS, 2016, 第 11 作者(28) Evidence for Conversion of Methanol to Formaldehyde in Nonhuman Primate Brain, ANALYTICAL CELLULAR PATHOLOGY, 2016, 第 4 作者 通讯作者(29) Formaldehyde as a trigger for protein aggregation and potential target for mitigation of age-related, progressive cognitive impairment, CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2016, 第 3 作者(30) Corrigendum to "A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections" J. Neurosci. Methods 251 (2015) 99���107, JOURNAL OF NEUROSCIENCE METHODS, 2016, 第 20 作者(31) Neurons Differentiated from Transplanted Stem Cells Respond Functionally to Acoustic Stimuli in the Awake Monkey Brain, CELL REPORTS, 2016, 第 23 作者 通讯作者(32) A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections (vol 251, pg 99, 2015), JOURNAL OF NEUROSCIENCE METHODS, 2016, 第 20 作者 通讯作者(33) Early adversity contributes to chronic stress induced depression-like behavior in adolescent male rhesus monkeys, BEHAVIOURAL BRAIN RESEARCH, 2016, 第 8 作者 通讯作者(34) 1-Methyl-4-Phenylpyridinium Stereotactic Infusion Completely and Specifically Ablated the Nigrostriatal Dopaminergic Pathway in Rhesus Macaque, PLOS ONE, 2015, 第 18 作者(35) Melatonin attenuates mptp-induced neurotoxicity via preventing cdk5-mediated autophagy and snca/-synuclein aggregation, AUTOPHAGY, 2015, 第 12 作者(36) A spontaneous depressive pattern in adult female rhesus macaques, SCIENTIFIC REPORTS, 2015, 第 14 作者(37) The temporary and accumulated effects of transcranial direct current stimulation for the treatment of advanced Parkinson's disease monkeys, SCIENTIFIC REPORTS, 2015, 第 16 作者(38) Severe dopaminergic neuron loss in rhesus monkey brain impairs morphine-induced conditioned place preference, FRONTIERS IN BEHAVIORAL NEUROSCIENCE, 2015, 第 6 作者 通讯作者(39) A quantitative approach to developing Parkinsonian monkeys (Macaca fascicularis) with intracerebroventricular 1-methyl-4-phenylpyridinium injections, JOURNAL OF NEUROSCIENCE METHODS, 2015, 第 19 作者(40) Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain, JOURNAL OF NEUROSCIENCE, 2015, 第 10 作者(41) The first observation of seasonal affective disorder symptoms in Rhesus macaque, BEHAVIOURAL BRAIN RESEARCH, 2015, 第 13 作者(42) An odor detection system based on automatically trained mice by relative go no-go olfactory operant conditioning, SCIENTIFIC REPORTS, 2015, 第 6 作者(43) Cortisol responses to chronic stress in adult macaques: Moderation by a polymorphism in the serotonin transporter gene, BEHAVIOURAL BRAIN RESEARCH, 2015, 第 9 作者(44) Divergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods, SCIENTIFIC REPORTS, 2015, 第 11 作者(45) Drift in centrality of different brain regions in an anatomical neural network with Parkinson���s disease: A view from complex network analysis, NEUROSCIENCE, 2015, (46) Light exposure before learning improves memory consolidation at night, SCIENTIFIC REPORTS, 2015, 第 5 作者(47) Face Recognition Increases during Saccade Preparation, PLOS ONE, 2014, 第 6 作者 通讯作者(48) Alzheimer's Disease and Methanol Toxicity (Part 2): Lessons from Four Rhesus Macaques (Macaca mulatta) Chronically Fed Methanol, JOURNAL OF ALZHEIMERS DISEASE, 2014, 第 18 作者 通讯作者(49) A new method for piercing the tentorium cerebelli for implanting fragile electrodes into the brain stem in the rhesus monkey (Macaca mulatta), JOURNAL OF NEUROPHYSIOLOGY, 2014, 第 12 作者(50) Smaller Is Better: Drift in Gaze Measurements due to Pupil Dynamics, PLOS ONE, 2014, 第 4 作者(51) Is Formaldehyde the Missing Link in AD Pathology? The Differential Aggregation of Amyloid-Beta with APOE Isoforms In Vitro, CURRENT ALZHEIMER RESEARCH, 2014, 第 3 作者(52) Alzheimer's Disease and Methanol Toxicity (Part 1): Chronic Methanol Feeding Led to Memory Impairments and Tau Hyperphosphorylation in Mice, JOURNAL OF ALZHEIMERS DISEASE, 2014, 第 12 作者 通讯作者(53) Acute Morphine Treatments Alleviate Tremor in 1Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Monkeys, PLOS ONE, 2014, 第 7 作者(54) The Role of Contrast Adaptation in Saccadic Suppression in Humans, PLOS ONE, 2014, 第 4 作者(55) Feature-reduction and semi-simulated data in functional connectivity-based cortical parcellation, NEUROSCIENCE BULLETIN, 2013, 第 6 作者(56) What interests them in the pictures The difference in eye tracking between rhesus monkeys and humans, Neuroscience Bulletin, 2013, 第 1 作者 通讯作者(57) Kisspeptin-10 Modulates the Proliferation and Differentiation of the Rhesus Monkey Derived Stem Cell Line: R366.4, SCIENTIFIC WORLD JOURNAL, 2013, 第 8 作者 通讯作者(58) Kisspeptin-10 Modulates the Proliferation and Differentiation of the Rhesus Monkey Derived Stem Cell Line: R366.4, THE SCIENTIFIC WORLD JOURNAL, 2013, 第 8 作者(59) How does the motor relearning program improve neurological function of brain ischemia monkeys?(star)star, NEURAL REGENERATION RESEARCH, 2013, 第 8 作者(60) Social rank and cortisol among female rhesus macaques(Macaca mulatta), Social rank and cortisol among female rhesus macaques(Macaca mulatta), 动物学研究, 2013, 第 9 作者(61) Interactive effects of morphine and dopaminergic compounds on spatial working memory in rhesus monkeys, NEUROSCIENCE BULLETIN, 2013, 第 5 作者(62) 恒河猕猴吗啡成瘾模型的初步建立, Morphine addiction in non-human primates using rhesus monkeys, 动物学研究, 2012, 第 4 作者(63) Nonhuman Primates: Important Animal Models for Regenerative Medicine, Science Supplement J, 2012, 第 1 作者(64) 运动再学习对猴脑缺血损伤后脑血流量的影响, Effect of Motor Relearning Program on Regional Cerebral Blood Flow(rCBF) of Rhesus Monkeys with Cerebral Ischemic Stroke, 中国康复, 2012, 第 8 作者(65) The egocentric spatial reference frame used in dorsal-lateral prefrontal working memory in primates, NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2012, 第 2 作者(66) 人类早期应激猕猴模型新进展, A New Advancement in Animal Model (Rhesus Monkey) of Human Early Adversity, 自然杂志, 2012, 第 2 作者(67) Effect of morphine on conditioned place preference in rhesus monkeys, ADDICTION BIOLOGY, 2012, 第 9 作者(68) Dissociable Modulation of Overt Visual Attention in Valence and Arousal Revealed by Topology of Scan Path, PLOS ONE, 2011, 第 9 作者(69) 心得安对ICR小鼠吗啡诱导的条件化位置偏爱记忆获得和提取的影响, Effects of propranolol on acquisition and retrieval of morphine- induced conditioned place preference memories in ICR mice, 动物学研究, 2011, 第 5 作者(70) 一种有效区分移植细胞和宿主细胞脑损伤模型的建立, A traumatic brain injury model for distinguishing between transplanted neural cells and host cells in vivo, 动物学研究, 2011, 第 4 作者(71) 非人灵长类动物模型睡眠研究在神经精神疾病的早期诊断和药效评价中的作用, Sleep disorder,a potential early diagnostic marker for psychiatric and neurodegenerative diseases, 动物学研究, 2011, 第 4 作者(72) 青春期小鼠与成年小鼠在吗啡和食物诱导条件化位置偏爱建立上的异同, Differences in morphine-induced and food-induced conditioned place preference between adolescent and adult mice, 动物学研究, 2011, 第 5 作者(73) Maternal separation produces lasting changes in cortisol and behavior in rhesus monkeys, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 第 9 作者(74) Environmental enrichment and chronic restraint stress in ICR mice: Effects on prepulse inhibition of startle and Y-maze spatial recognition memory, BEHAVIOURAL BRAIN RESEARCH, 2010, 第 4 作者(75) 吗啡对猕猴瞳孔光反应能力的影响, Effects of Morphine on Pupillary Light Reflex in Monkeys, 动物学研究, 2010, 第 5 作者(76) 快速跳视——一个有潜力的人类精神疾病的病变检测手段与药效评价标准, Saccade: A Potential Diagnostic Tool and Drug Efficacy Test Criterion for Mental Disorders, 动物学研究, 2010, 第 2 作者(77) 用于研究快速扫视对瞳孔光反射调制作用的新方法, A New Method to Explore the Modulation from the Saccadic System, 动物学研究, 2010, 第 5 作者(78) 用于研究快速扫视对瞳孔光反射调制作用的新方法, A New Method to Explore the Modulation from the Saccadic System, 动物学研究, 2010, 第 5 作者(79) Irregular morphine administration affects the retention but not acquisition of conditioned place preference in rats, BRAIN RESEARCH, 2010, 第 3 作者(80) A new MRI approach for accurately implanting microelectrodes into deep brain structures of the rhesus monkey (Macaca mulatta), JOURNAL OF NEUROSCIENCE METHODS, 2010, 第 10 作者(81) The Effects of Visual Object Size in The Depth Perception in KM Mouse, PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2010, 第 3 作者(82) 大鼠成年前异常生活环境对其成年后恐惧记忆的影响, Effects of Abnormal Early Rearing Environments on Fear Memory in Adult Rats, ZOOLOGICAL RESEARCH, 2009, 第 3 作者(83) 长期注射吗啡对戒断后小鼠Y-迷宫空间识别记忆的影响, Effects of Withdrawal on Y-maze Spatial Recognition Memory in Mice after Long-term Morphine Injection, 动物学研究, 2009, 第 4 作者(84) Different masking effects on "hole" and "no-hole" figures, JOURNAL OF VISION, 2009, 第 5 作者(85) 拓扑差异物体的构型处理:一项脑电研究, 中国科学:C辑, 2009, 第 5 作者(86) 拓扑差异物体的构型处理:一项脑电研究, 中国科学:C辑, 2009, 第 5 作者(87) Configsural processing of different topolosically structured figures: an ERP Study, SCIENCE IN CHINA. SERIES C: LIFE SCIENCE, 2009, 第 5 作者(88) 猕猴毛发皮质醇测量方法探索, A Reliable Procedure for Measuring Cortisol Levels in Rhesus Macaque Hair Samples, 动物学研究, 2009, 第 6 作者(89) Configural processing of different topologically structured figures: an ERP Study, SCIENCE IN CHINA SERIES C-LIFE SCIENCES, 2009, 第 5 作者(90) Somatosensory Cortices Are Required for the Acquisition of Morphine-Induced Conditioned Place Preference, PLOS ONE, 2009, 第 3 作者(91) 猕猴毛发皮质醇测量方法探索, A Reliable Procedure for Measuring Cortisol Levels in Rhesus Macaque Hair Samples, 动物学研究, 2009, 第 6 作者(92) 长期注射吗啡对戒断后小鼠Y-迷宫空间识别记忆的影响, Effects of Withdrawal on Y-maze Spatial Recognition Memory in Mice after Long-term Morphine Injection, 动物学研究, 2009, 第 4 作者(93) 猕猴大脑运动系统编码策略的研究, 中国神经科学学会第四次会员代表大会暨第八届全国学术会议, 2009, 第 1 作者(94) Maze model to study spatial learning and memory in freely moving monkeys, JOURNAL OF NEUROSCIENCE METHODS, 2008, 第 8 作者 通讯作者(95) Extremely low-frequency electromagnetic field exposure during chronic morphine treatment strengthens downregulation of dopamine D2 receptors in rat dorsal hippocampus after morphine withdrawal, NEUROSCIENCE LETTERS, 2008, 第 9 作者(96) Effects of addiction-associated and affective stimuli on the attentional blink in a sample of abstinent opiate dependent patients, JOURNAL OF PSYCHOPHARMACOLOGY, 2008, 第 4 作者(97) Chronic morphine selectively impairs cued fear extinction in rats: Implications for anxiety disorders associated with opiate use, NEUROPSYCHOPHARMACOLOGY, 2008, 第 11 作者(98) 眼动和知觉, 第三届全国脑与认知科学学术研讨会暨脑与认知科学国际研讨会, 2007, 第 1 作者(99) Reliability of oculomotor command signals carried by individual neurons, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2007, 第 1 作者 通讯作者(100) Learning large-scale spatial relationships in a maze and effects of MK-801 on retrieval in the rhesus monkey, DEVELOPMENTAL NEUROBIOLOGY, 2007, 第 10 作者 通讯作者(101) Gender related effects of heroin abuse on the simple reaction time task, ADDICTIVE BEHAVIORS, 2006, (102) Dynamic changes in orbitofrontal neuronal activity in rats during opiate administration and withdrawal, NEUROSCIENCE, 2006, (103) EEG activities in the orbitofrontal cortex and dorsolateral prefrontal cortex during the development of morphine dependence, tolerance and withdrawal in rhesus monkeys, BRAIN RESEARCH, 2005, (104) Effects of extremely low-frequency electromagnetic fields on morphine-induced conditioned place preferences in rats, NEUROSCIENCE LETTERS, 2005, (105) The clothing effect: Tactile neurons in the precentral gyrus do not respond to the touch of the familiar primate chair, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, (106) coding the location of objects in the dark, 1997, 第 1 作者(107) Visuospatial properties of ventral premotor cortex, JOURNAL OF NEUROPHYSIOLOGY, 1997, (108) 猴前额叶皮层内注射α_(2)肾上腺素能拮抗剂损害延缓GO/NO-GO任务操作, Prefrontal injection of the #alpha#_(2)-adrenergic antagonist yohimbine impairs performance of a delayed GO/NO-GO task in monkeys, 生理学报, 1994, 第 2 作者(109) RESERPINE IMPAIRS SPATIAL WORKING-MEMORY PERFORMANCE IN MONKEYS - REVERSAL BY THE ALPHA-2-ADRENERGIC AGONIST CLONIDINE, BRAIN RESEARCH, 1993, (110) The Relation Between Evolution of Spatial working Memory Function and of Morphology of The Dorsolateral Prefrontal Cortex Among The Rhesus Monkey,Slow Loris and Tree Shrew, 动物学研究, 1993, 第 2 作者(111) deficit of delayed go/no-go task performance induced by local injection of alpha-2 adrenergic antagonist yohimbine into the dorsolateral prefrontal cortex in monkeys, Acta Psychologic Sinica, 1992, 第 1 作者(112) the effects of acetylcholine (ach) applied iontophoretically on neurons of dorsalprefrontal cortex in the tree shrew, Primatology Today, 1991, 第 1 作者(113) excitative and inhibitory effects clonidine-induced in the slow lores and rhesusmonkey, Primatology Today, 1991, 第 1 作者(114) the effects of acetylcholine (ach) on neurons sensitive to auditory and visual stimulation of dorsal prefrontal cortex in tree shrews, Primatology Today, 1991, 第 1 作者(115) the influence of auditory, visual stimulation on the unit activity of dorsal prefrontal cortices in the tree shrew, 1991, 第 1 作者
发表著作
( 1 ) 神经生物学基础(第41章: 脑干的运动控制), Basis of neurobiology, 北京大学出版社, 2009-02, 第 1 作者( 2 ) 思维的力量, The power of thinking, 云南科技出版社, 2010-08, 第 3 作者
科研活动
科研项目
( 1 ) .科技创新2030-重大项目课题:脑疾病模型猴制备与疾病早期诊断指标建立 ,2021-12 至 2026-11,5500万元,主持, 负责人, 国家任务, 2021-12--2026-11( 2 ) 中国科学院科技服务网络计划(STS重点项目):明眸春雨-璀璨行动二期,2021-01 至 2022-06,950万元, 主持, 负责人, 中国科学院计划, 2021-01--2022-06( 3 ) 通过环境和基因因素相互作用诱导建立阿尔茨海默症猕猴, 负责人, 国家任务, 2020-01--2022-12( 4 ) 基因编辑创制发育退行性与神经退行性疾病的猴模型, 负责人, 国家任务, 2019-10--2024-10( 5 ) 自闭症诊治的基础和应用研究, 负责人, 地方任务, 2019-09--2024-07( 6 ) 脑认知与类脑前沿研究, 负责人, 中国科学院计划, 2018-07--2023-07( 7 ) 阿尔兹海默病(AD)猕猴自发模型的筛选鉴定, 负责人, 国家任务, 2018-01--2021-12( 8 ) 基于病毒介导基因编辑的孤独症非人灵长类模型建立及神经环路研究-2, 负责人, 国家任务, 2018-01--2019-12( 9 ) 面向猕猴模型三维视觉认知脑功能解析的高通量实验装置, 负责人, 中国科学院计划, 2018-01--2019-12( 10 ) XXX项目(保密项目), 负责人, 中国科学院计划, 2018-01--2020-12( 11 ) 建立阿尔茨海默病(AD)转基因猴模型, 负责人, 国家任务, 2015-01--2018-12( 12 ) 情绪相关的皮层下通路--基于猕猴的研究, 负责人, 国家任务, 2014-01--2016-12( 13 ) 先导B-学习记忆和老年痴呆, 负责人, 国家任务, 2012-07--2017-08