0710J6-再生医学
071008-发育生物学
071009-细胞生物学

人类胎盘发生的细胞和分子机制与妊娠相关疾病
干细胞与人类生育力的维持和重建。

2003-12--2005-12   加拿大渥太华健康研究所（OHRI）   博士后
1999-09--2002-07   中国科学院动物研究所   博士
1995-09--1998-07   北京师范大学   硕士
1991-09--1995-07   北京师范大学   本科
1988-09--1991-07   内蒙古赤峰二中   攻读高中

-- 研究生

-- 博士

   

2021-12~现在, 干细胞与再生医学创新研究院, 副院长
2020-07~现在, 中国科学院动物研究所, 所务委员
2017-05~现在, 干细胞与生殖生物学国家重点实验室, 主任
2013-01~2020-09,干细胞与生殖生物学国家重点实验室, 党总支书记
2013-01~2017-05,干细胞与生殖生物学国家重点实验室, 副主任、党总支书记
2006-09~现在, 中国科学院动物研究所, 研究员
2004-01~2006-09,中国科学院动物研究所, 副研究员
2003-01~2003-12,中国科学院动物研究所, 助理研究员
1998-07~2002-12,中国科学院动物研究所, 研究实习员

2021-07-25-今,中国生物物理学会女科学家分会, 副秘书长
2021-02-11-今,Frontiers in Cell and Developmental Biology （Front Cell Dev Bio）, Review Editors
2021-01-22-今,Fundamental Research （双月刊）, 编委（医学领域）
2020-12-30-今,生物医学转化, 第一届编委会委员
2020-07-22-今,Cell Reports Medicine, 编委
2017-12-31-今,CELL PROLIFERATION, 编委
2017-04-01-今,中国医师协会整合医学医师分会 整合医学生殖医学专业委员会(学组) 第一届委员会, 副主任委员
2016-09-11-今,妇幼健康研究会母胎医学专业委员会, 常务委员
2016-01-01-今,中国生理学会生殖科学专业委员会（第24届）, 委员
2012-12-31-今,Biol Reprod杂志编委会委员, 编委
2009-01-01-今,中国动物学会生殖生物学分会, 理事
2001-01-01-今,美国生殖生物学学会会员,

免疫组织化学实验
现代生殖医学之生理基础
发育生物学
生殖生物学
免疫组织化学实验技术
生殖生理学
细胞生物学大实验
生殖生物学研究进展

   

（1） 中国科学院大学教学科研工作“领雁银奖、振翅奖”, 研究所（学校）, 2021
（2） 2020年“中国科学院朱李月华优秀教师奖”, , 部委级, 2020
（3） 中国科学院优秀导师奖, 部委级, 2020
（4） 国家百千万人才工程，授予“有突出贡献中青年专家”荣誉称号, , 国家级, 2020
（5） 全国妇幼健康科学技术奖 自然科学奖, 二等奖, 国家级, 2017
（6） 全国妇幼健康科学技术奖 自然科学奖, 二等奖, 国家级, 2017
（7） 国家人口和计划生育委员会人口和计划生育科学技术进步 优秀科技成果奖, 一等奖, 国家级, 2011
（8） 黑龙江省科学技术奖, 三等奖, 省级, 2008
（9） 黑龙江省科学技术奖, 二等奖, 省级, 2008
（10） 教育部科学技术进步奖（自然科学）, 二等奖, 部委级, 2008

[1] 赵建国, 王霄, 曹春伟, 海棠, 周琪, 王红梅, 张颖, 贾启涛, 郑千涛. 一种突变基因及其用于构建斑色鱼鳞癣小型猪模型的用途. CN: CN110846321B, 2021-11-19.
[2] 周琪, 赵建国, 海棠, 贾启涛, 曹春伟, 王红梅, 张颖, 郑千涛, 王霄. 一种突变基因及其用于构建蹼足病小型猪模型的用途. CN: CN110846330B, 2021-08-27.
[3] 王红梅, 曾维俊, 宋宇, 顾奇, 孙海旋, 刘欣瑞, 钱俊, 赵振英. 胚胎培养装置. CN: CN112662553A, 2021-04-16.
[4] 肖冬根, 王红梅, 曾维俊, 于福鑫, 肖振宇, 孙海旋, 杨语谌, 梁伟国, 杨森. 胚胎长时程培养系统. CN: CN112625907A, 2021-04-09.
[5] 周琪, 胡宝洋, 郝捷, 李伟, 吴骏, 王柳, 郭保杰, 李仲文, 高婷婷, 陈燕霞, 王红梅. 一种多能干细胞、药物组合物及其制备方法与用途. CN: CN112538456A, 2021-03-23.
[6] 宋飞飞, 王策, 马玉婷, 吴云良, 陈忠祥, 裴智果, 严心涛, 钟金凤, 王红梅, 闫龙. 利用鞘液逆流防止细胞阻塞的微流控芯片. CN: CN211111935U, 2020-07-28.
[7] 王红梅, 闫龙, 杨晓葵, 洪黎明, 吴骏, 郝捷. 脐带间充质干细胞条件培养基的用途. CN: CN110478368A, 2019-11-22.
[8] 王红梅, 刘见桥, 周琪, 吴乙璇, 闫龙, 郝捷, 李莉, 王柳, 李天达. 卵巢注射装置及诊断、预防或治疗卵巢疾病的装置. CN: CN110025368A, 2019-07-19.
[9] 王红梅, 周琪, 赵建国, 孟安明, 曹春伟, 海棠, 祁蒙. 一种猪MITF基因突变的检测方法. CN: CN107034268B, 2017-08-11.

   

[1] Yiming Wang, Xiangxiang Jiang, Lei Jia, Xulun Wu, Hao Wu, Yue Wang, Qian Li, Ruoxuan Yu, Hongmei Wang, Zhenyu Xiao, Xiaoyan Liang. A Single-Cell Characterization of Human Post-implantation Embryos Cultured In Vitro Delineates Morphogenesis in Primary Syncytialization. Frontiers in Cell and Developmental Biology[J]. 2022, 10: https://doaj.org/article/037cbec3e90d45308fbf93efb797da03.
[2] 王红梅. The diversity of trophoblast cells and niches of placenta accreta spectrum disorders revealed by single-cell RNA sequencing. Frontiers in Cell and Developmental Biology[J]. 2022, [3] 王红梅. Workflow for Performing Genetic Manipulation in Human Trophoblast Stem Cells Using CRISPR/Cas9 Technology. Methods in moclecular biology[J]. 2022, [4] 王红梅. Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development. Nature Genetics[J]. 2022, [5] Wan Tu, Dongdong Ni, Hua Yang, Feiyan Zhao, Chen Yang, Xuehan Zhao, Zhiyuan Guo, Kunyuan Yu, Jingzi Wang, Zhaoshan Hu, Zixuan Chen, Yan Zhao, Zhenbo Wang, Fei Gao, Long Yan, Xiaokui Yang, Lan Zhu, Hongmei Wang. Deciphering the dynamics of the ovarian reserve in cynomolgus monkey through a quantitative morphometric study. Science Bulletin. 2022, 67(18): 1854-1859, http://dx.doi.org/10.1016/j.scib.2022.08.027.
[6] Wang, Yiming, Wu, Hao, Jiang, Xiangxiang, Jia, Lei, Wang, Meijiao, Rong, Yin, Chen, Shuo, Wang, Yue, Xiao, Zhenyu, Liang, Xiaoyan, Wang, Hongmei. LMNA Determines Nuclear Morphology During Syncytialization of Human Trophoblast Stem Cells. FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY[J]. 2022, 10: http://dx.doi.org/10.3389/fcell.2022.836390.
[7] 王红梅. Primate gastrulation and early organogenesis at single-cell resolution. Nature[J]. 2022, [8] []. A Uterus-Inspired Niche Drives Blastocyst Development to the Early Organogenesis. Advanced Science[J]. 2022, https://onlinelibrary.wiley.com/doi/10.1002/advs.202202282.
[9] 王红梅. Dissecting the fate of 1 Foxl2-expressing cells in fetal ovary using lineage tracing and Single-Cell Transcriptomics. Cell Discovery[J]. 2022, [10] 王红梅. Generation of Human Trophoblast Stem Cell-Dependent Placental In Vitro Models. Methods in molecular biology[J]. 2022, [11] Li, Qian, Wu, Hao, Wang, Yue, Wang, Hongmei. Current understanding in deciphering trophoblast cell differentiation during human placentation. BIOLOGY OF REPRODUCTIONnull. 2022, 107(1): 317-326, http://dx.doi.org/10.1093/biolre/ioac083.
[12] Jinglei Zhai, Zhenyu Xiao, Yiming Wang, Hongmei Wang. Human embryonic development: from peri-implantation to gastrulation. Trends in Cell Biology. 2022, 32(1): 18-29, [13] Wu, Hao, Liao, Shujie, Wang, Yiming, Guo, Ming, Lin, Xingguang, Wu, Jianli, Wang, Renjie, Lv, Dan, Wu, Di, He, Mengzhou, Hu, Bai, Long, Rui, Peng, Jing, Yang, Hui, Yin, Heng, Wang, Xin, Huang, Zhixiang, Lan, Ke, Zhou, Yanbin, Zhang, Wei, Xiao, Zhenyu, Zhao, Yun, Deng, Dongrui, Wang, Hongmei. Molecular evidence suggesting the persistence of residual SARS-CoV-2 and immune responses in the placentas of pregnant patients recovered from COVID-19. CELL PROLIFERATION[J]. 2021, 54(9): http://dx.doi.org/10.1111/cpr.13091.
[14] Cui, D, Liu, Y, Jiang, X, Ding, C, Poon, L C, Wang, H, Yang, H. Single-cell RNA expression profiling of SARS-CoV-2-related ACE2 and TMPRSS2 in human trophectoderm and placenta. ULTRASOUND IN OBSTETRICS & GYNECOLOGY[J]. 2021, 57(2): 248-256, http://dx.doi.org/10.1002/uog.22186.
[15] Li, Xia, Wang, Yiming, Ma, Ruoyu, Liu, Xin, Song, Biaobiao, Duan, Yongchao, Guo, Jia, Feng, Guihai, Cui, Tongtong, Wang, Liu, Hao, Jie, Wang, Hongmei, Gu, Qi. Reconstruction of functional uterine tissues through recellularizing the decellularized rat uterine scaffolds by MSCs in vivo and in vitro. BIOMEDICAL MATERIALS[J]. 2021, 16(3): https://www.webofscience.com/wos/woscc/full-record/WOS:000625107600001.
[16] Yongcun Qu, Qi Chen, Shanshan Guo, Chiyuan Ma, Yonggang Lu, Junchao Shi, Shichao Liu, Tong Zhou, Taichi Noda, Jingjing Qian, Liwen Zhang, Xili Zhu, Xiaohua Lei, Yujing Cao, Wei Li, Wei Li, Nicolas Plachta, Martin MMatzuk, Masahito Ikawa, Enkui Duan, Ying Zhang, Hongmei Wang. Cooperation-based sperm clusters mediate sperm oviduct entry and fertilization. 蛋白质与细胞:英文版[J]. 2021, 12(10): 810-817, http://lib.cqvip.com/Qikan/Article/Detail?id=7105874304.
[17] Rui Yan, Chan Gu, Di You, Zhongying Huang, Jingjing Qian, Qiuyun Yang, Xin Cheng, Lin Zhang, Hongmei Wang, Ping Wang, Fan Guo. Decoding dynamic epigenetic landscapes in human oocytes using single-cell multi-omics sequencing. Cell Stem Cell[J]. 2021, 28(9): 1641-1656, [18] Liang, Guixian, Zhou, Chunyu, Jiang, Xiangxiang, Zhang, Yifan, Huang, Baofeng, Gao, Suwei, Kang, Zhixin, Ma, Dongyuan, Wang, Fengchao, Gottgens, Berthold, Wang, Hongmei, Han, JingDong J, Liu, Feng. De novo generation of macrophage from placenta-derived hemogenic endothelium. DEVELOPMENTAL CELL[J]. 2021, 56(14): 2121-+, http://dx.doi.org/10.1016/j.devcel.2021.06.005.
[19] 谭韬, 马怀孝, 郑萍, 王红梅, 李磊. 灵长类发育研究新阶段：猴胚胎体外培养至受精后20天. 前沿科学[J]. 2020, 14(1): 80-83, http://lib.cqvip.com/Qikan/Article/Detail?id=7101503851.
[20] Xiao, Zhenyu, Yan, Long, Liang, Xiaoyan, Wang, Hongmei. Progress in deciphering trophoblast cell differentiation during human placentation. CURRENT OPINION IN CELL BIOLOGY[J]. 2020, 67(18): 86-91, http://dx.doi.org/10.1016/j.ceb.2020.08.010.
[21] Yan, Long, Wu, Yixuan, Li, Li, Wu, Jun, Zhao, Feiyan, Gao, Zheng, Liu, Wenjing, Li, Tianda, Fan, Yong, Hao, Jie, Liu, Jianqiao, Wang, Hongmei. Clinical analysis of human umbilical cord mesenchymal stem cell allotransplantation in patients with premature ovarian insufficiency. CELL PROLIFERATION[J]. 2020, 53(12): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7705906/.
[22] Zhao, Yan, Ma, Jiao, Yi, Peiye, Wu, Jun, Zhao, Feiyan, Tu, Wan, Liu, Wenjing, Li, Tianda, Deng, Yan, Hao, Jie, Wang, Hongmei, Yan, Long. Human umbilical cord mesenchymal stem cells restore the ovarian metabolome and rescue premature ovarian insufficiency in mice. STEM CELL RESEARCH & THERAPY[J]. 2020, 11(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000590101700001.
[23] Lim, Hui Yi Grace, Alvarez, Yanina D, Gasnier, Maxime, Wang, Yiming, Tetlak, Piotr, Bissiere, Stephanie, Wang, Hongmei, Biro, Mate, Plachta, Nicolas. Keratins are asymmetrically inherited fate determinants in the mammalian embryo. NATURE[J]. 2020, 585(7825): 404-+, http://dx.doi.org/10.1038/s41586-020-2647-4.
[24] Guo, Shanshan, Cui, Xiuhong, Jiang, Xiangxiang, Duo, Shuguang, Li, Shiwen, Gao, Fei, Wang, Hongmei. Tracing the origin of the placental trophoblast cells in mouse embryo development. BIOLOGY OF REPRODUCTION[J]. 2020, 102(3): 598-606, http://dx.doi.org/10.1093/biolre/ioz201.
[25] Hong, Liming, Yan, Long, Xin, Zhimin, Hao, Jie, Liu, Wenjing, Wang, Shuyu, Liao, Shujie, Wang, Hongmei, Yang, Xiaokui. Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2020, 12(5): 372-385, http://lib.cqvip.com/Qikan/Article/Detail?id=7102219899.
[26] Ma, Huaixiao, Wang, Hongmei, Zheng, Ping, Li, Lei. Comments on 'In vitro culture of cynomolgus monkey embryos beyond early gastrulation'. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2020, 12(5): 400-402, http://lib.cqvip.com/Qikan/Article/Detail?id=7102219902.
[27] Gao, Hui, Liu, Chao, Wu, Bingbing, Cui, Hang, Zhao, Yan, Duan, Yongchao, Gao, Fei, Gu, Qi, Wang, Hongmei, Li, Wei. Effects of Different Biomaterials and Cellular Status on Testicular Cell Self-Organization. ADVANCED BIOSYSTEMS[J]. 2020, 4(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000535312900001.
[28] Jiang, Xiangxiang, Wang, Hongmei. Macrophage subsets at the maternal-fetal interface. CELLULAR & MOLECULAR IMMUNOLOGY. 2020, 17(8): 889-891, http://dx.doi.org/10.1038/s41423-020-0435-6.
[29] Gu Zhen, Guo Jia, 王红梅, Wen Yongqiang, 顾奇. Bioengineered microenvironment to culture early embryos. CELL PROLIFERATION[J]. 2020, 53(2): https://www.webofscience.com/wos/woscc/full-record/WOS:000506179700001.
[30] 王红梅. 哺乳动物早期胚胎发育研究进展和伦理. 生物医学转化[J]. 2020, 1(1): 35-42, http://lib.cqvip.com/Qikan/Article/Detail?id=7103692883.
[31] Ma, Jiao, Wu, Jun, Han, Lei, Jiang, Xiangxiang, Yan, Long, Hao, Jie, Wang, Hongmei. Comparative analysis of mesenchymal stem cells derived from amniotic membrane, umbilical cord, and chorionic plate under serum-free condition. STEM CELL RESEARCH & THERAPY[J]. 2019, 10(1): https://doaj.org/article/f20e6380f95d4ae3abf7ff1f155f8fa9.
[32] Ma, Huaixiao, Zhai, Jinglei, Wan, Haifeng, Jiang, Xiangxiang, Wang, Xiaoxiao, Wang, Lin, Xiang, Yunlong, He, Xiechao, Zhao, ZhenAo, Zhao, Bo, Zheng, Ping, Li, Lei, Wang, Hongmei. In vitro culture of cynomolgus monkey embryos beyond early gastrulation. SCIENCE[J]. 2019, 366(6467): 836-+, [33] Wang, Rui, Yu, Ruoxuan, Zhu, Cheng, Lin, HaiYan, Lu, Xiaoyin, Wang, Hongmei. Tubulin detyrosination promotes human trophoblast syncytium formation. JOURNAL OF MOLECULAR CELL BIOLOGY[J]. 2019, 11(11): 967-978, http://lib.cqvip.com/Qikan/Article/Detail?id=7100725234.
[34] Liming Hong, Long Yan, Zhimin Xin, Jie Hao, Wenjing Liu, Shuyu Wang, Shujie Liao, Hongmei Wang, Xiaokui Yang, Anming Meng. Protective effects of human umbilical cord mesenchymal stem cell-derived conditioned medium on ovarian damage. Journal of Molecular Cell Biology. 2019, 12(5): 372-385, [35] Cao, Chunwei, Zhang, Ying, Jia, Qitao, Wang, Xiao, Zheng, Qiantao, Zhang, Hongyong, Song, Ruigao, Li, Yongshun, Luo, Ailing, Hong, Qianlong, Qin, Guosong, Yao, Jing, Zhang, Nan, Wang, Yanfang, Wang, Hongmei, Zhou, Qi, Zhao, Jianguo. An exonic splicing enhancer mutation in DUOX2 causes aberrant alternative splicing and severe congenital hypothyroidism in Bama pigs. DISEASE MODELS & MECHANISMS[J]. 2019, 12(1): https://doaj.org/article/d3b310007c4b4e3198ba488905667dd5.
[36] Tao, Yong, Tartia, Alina, Lawson, Maralee, Zelinski, Mary B, Wu, Wei, Liu, JiaYin, Smitz, Johan, Leveille, MarieClaude, Leader, Arthur, Wang, Hongmei, Ramsay, Timothy, Liu, X Johne. Can peri-ovulatory putrescine supplementation improve egg quality in older infertile women?. JOURNAL OF ASSISTED REPRODUCTION AND GENETICSnull. 2019, 36(3): 395-402, [37] Wang, Yue, Wang, Hongmei. Successful derivation of human trophoblast stem cells. BIOLOGY OF REPRODUCTIONnull. 2018, 99(2): 271-272, https://www.webofscience.com/wos/woscc/full-record/WOS:000446331500004.
[38] Jiang, Yuan, Yan, Long, Xia, Longkuo, Lu, Xiaoyin, Zhu, Wenliang, Ding, Dewen, Du, Mingxia, Zhang, Da, Wang, Hongmei, Hu, Baoyang. Zinc finger E-box-binding homeobox 1 (ZEB1) is required for neural differentiation of human embryonic stem cells. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2018, 293(50): 19317-19329, http://dx.doi.org/10.1074/jbc.RA118.005498.
[39] Jiang, Xiangxiang, Du, MeiRong, Li, Min, Wang, Hongmei. Three macrophage subsets are identified in the uterus during early human pregnancy. CELLULAR & MOLECULAR IMMUNOLOGY[J]. 2018, 15(12): 1027-1037, http://dx.doi.org/10.1038/s41423-018-0008-0.
[40] Liu, Yawei, Fan, Xiaoying, Wang, Rui, Lu, Xiaoyin, Dang, YanLi, Wang, Huiying, Lin, HaiYan, Zhu, Cheng, Ge, Hao, Cross, James C, Wang, Hongmei. Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta. CELL RESEARCH[J]. 2018, 28(8): 819-832, http://lib.cqvip.com/Qikan/Article/Detail?id=676354493.
[41] Chang, WenLin, Liu, YaWei, Dang, YanLi, Jiang, XiangXiang, Xu, Honglin, Huang, Xing, Wang, YanLing, Wang, Haibin, Zhu, Cheng, Xue, LiQun, Lin, HaiYan, Meng, Wenxiang, Wang, Hongmei. PLAC8, a new marker for human interstitial extravillous trophoblast cells, promotes their invasion and migration. DEVELOPMENT[J]. 2018, 145(2): http://dx.doi.org/10.1242/dev.148932.
[42] Yawei Liu, Xiaoying Fan, Rui Wang, Xiaoyin Lu, Yan-Li Dang, Huiying Wang, Hai-Yan Lin, Cheng Zhu, Hao Ge, James C. Cross, Hongmei Wang. Single-cell RNA-seq reveals the diversity of trophoblast subtypes and patterns of differentiation in the human placenta. 细胞研究：英文版[J]. 2018, 28(8): 819-832, http://lib.cqvip.com/Qikan/Article/Detail?id=676354493.
[43] 王红梅, 杜美蓉. 人类胎盘滋养层细胞的分化与妊娠相关疾病. 生命科学[J]. 2017, 29(1): 15-20, [44] Long Yan, Yue Li, Zixiao Shi, Xiaoyin Lu, Jiao Ma, Baoyang Hu, Jianwei Jiao, Hongmei Wang. The zinc finger E-box-binding homeobox 1 ( Zeb1 ) promotes the conversion of mouse fibroblasts into functional neurons. The Journal of Biological Chemistry. 2017, 292(31): 12959-12970, http://dx.doi.org/10.1074/jbc.M116.771493.
[45] Lu, Xiaoyin, Wang, Rui, Zhu, Cheng, Wang, Haibin, Lin, HaiYan, Gu, Yan, Cross, James C, Wang, Hongmei. Fine-Tuned and Cell-Cycle-Restricted Expression of Fusogenic Protein Syncytin-2 Maintains Functional Placental Syncytia. CELL REPORTS[J]. 2017, 21(5): 1150-1159, http://dx.doi.org/10.1016/j.celrep.2017.10.019.
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[101] Yang, Qing, Chen, ShengPing, Zhang, XiaoPing, Wang, Hongmei, Zhu, Cheng, Lin, HaiYan. Smurf2 Participates in Human Trophoblast Cell Invasion by Inhibiting TGF-beta Type I Receptor. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY[J]. 2009, 57(6): 605-612, https://www.webofscience.com/wos/woscc/full-record/WOS:000266294700009.
[102] 陈升平, 王冬娜, 张晓萍, 祝诚, 王红梅. 蛋白酶体亚基LMP-2在卵巢上皮性肿瘤中的表达. 中国误诊学杂志[J]. 2009, 1557-1558, http://lib.cqvip.com/Qikan/Article/Detail?id=31447626.
[103] Zhou, Z, Shen, T, Zhang, B H, Lv, X Y, Lin, H Y, Zhu, C, Xue, L Q, Wang, H. The proprotein convertase furin in human trophoblast: Possible role in promoting trophoblast cell migration and invasion. PLACENTA[J]. 2009, 30(11): 929-938, http://dx.doi.org/10.1016/j.placenta.2009.09.003.
[104] Qing Yang, ShengPing Chen, XiaoPing Zhang, Hongmei Wang, Cheng Zhu, HaiYan Lin. Smurf2 Participates in Human Trophoblast Cell Invasion by Inhibiting TGF-β Type I Receptor. Journal of Histochemistry and Cytochemistry. 2009, 57(6): 605-612, http://kns.cnki.net/KCMS/detail/detail.aspx?QueryID=0&CurRec=2&recid=&FileName=SJIXEF393884A31AA4A2F64BD7E300997994&DbName=SJIXLAST&DbCode=SJIX&yx=&pr=&URLID=&bsm=.
[105] Yin JiangXia, Wang HongMei, Racey, Paul, Zhang ShuYi. Distribution and ultrastructure of Merkel cell of the fishing bat (Myotis ricketti). SCIENCE IN CHINA SERIES C-LIFE SCIENCES[J]. 2009, 52(9): 802-806, http://www.corc.org.cn/handle/1471x/2402616.
[106] 殷江霞, 王红梅, Paul, Racey, 张树义. 食鱼蝙蝠Merkel细胞的分布及超微结构. 中国科学：C辑[J]. 2009, 844-848, http://lib.cqvip.com/Qikan/Article/Detail?id=31720675.
[107] Zhang, Baohua, Yang, Qing, Lin, Haiyan, Zhu, Cheng, Wang, Hongmei. Smurf2 participates in human cytotrophoblast cell invasion during pregnancy by inhibiting TGF-beta type I receptor signaling.. REPRODUCTIVE SCIENCESnull. 2008, 15(2): 205A-205A, https://www.webofscience.com/wos/woscc/full-record/WOS:000253581600516.
[108] 周智, 张保华, 祝诚, 薛立群, 王红梅. 前蛋白转换酶Furin和PC7在小鼠母胎界面的动态表达及其在胚胎粘附和扩展中的作用. 动物学报[J]. 2008, 54(5): 877-884, http://lib.cqvip.com/Qikan/Article/Detail?id=28745136.
[109] Zhang, Heng, Li, Qinglei, Lin, Haiyan, Yang, Qing, Wang, Hongmei, Zhu, Cheng. Role of PPAR gamma and its gonadotrophic regulation in rat ovarian granulosa cells in vitro. NEUROENDOCRINOLOGY LETTERS[J]. 2007, 28(3): 289-294, http://www.corc.org.cn/handle/1471x/2383443.
[110] Yang, Qing, Lin, HaiYan, Wang, HongXing, Zhang, Heng, Zhang, Xiaoping, Wang, HongMei, Zhu, Cheng. Expression of Smad ubiquitin regulatory factor 2 (Smurf2) in rhesus monkey endometrium and placenta during early pregnancy. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY[J]. 2007, 55(5): 453-460, https://www.webofscience.com/wos/woscc/full-record/WOS:000245935300004.
[111] 王红梅. Wild fulvous fruit bats (Rousettus leschenaulti) exhibit human-like menstrual cycle.. Biol Reprod. 2007, [112] Wang, Hongmei, Tsang, Benjamin K. Nodal signalling and apoptosis. REPRODUCTION[J]. 2007, 133(5): 847-853, https://www.webofscience.com/wos/woscc/full-record/WOS:000248212000001.
[113] Wang, Hongmei, Jiang, JinYi, Zhu, Cheng, Peng, Chun, Tsang, Benjamin K. Role and regulation of Nodal/Activin receptor-like kinase 7 signaling pathway in the control of ovarian follicular atresia. MOLECULAR ENDOCRINOLOGY[J]. 2006, 20(10): 2469-2482, https://www.webofscience.com/wos/woscc/full-record/WOS:000240785100017.
[114] 高红军, 代解杰, 王红星, 林海燕, 王红梅. 血管新生调节因子VEGF及其受体在恒河猴正常妊娠和药物流产胎盘中的表达. 中国计划生育学杂志[J]. 2005, 13(6): 356-359, http://lib.cqvip.com/Qikan/Article/Detail?id=16043061.
[115] 张璇, 王红梅, 钱东, 林海燕, 刘国艺, 李庆雷, 祝诚. 一氧化氮对小鼠胚胎围植入期子宫VEGF及其受体表达的调节. 动物学报[J]. 2004, 50(1): 55-61, http://lib.cqvip.com/Qikan/Article/Detail?id=9258682.
[116] Wang, HM, Zhang, X, Qian, D, Lin, HY, Li, QL, Liu, DL, Liu, GY, Yu, XD, Zhu, C. Effect of ubiquitin-proteasome pathway on mouse blastocyst implantation and expression of matrix metal loproteinases-2 and-9. BIOLOGY OF REPRODUCTION[J]. 2004, 70(2): 481-487, https://www.webofscience.com/wos/woscc/full-record/WOS:000188395400030.
[117] Zhang Xuan, Wang Hongmei, Qian Dong, Lin Haiyan, Liu Guoyi, Li Qinglei, Zhu Cheng. Effect of NO on the expression of VEGF and its receptors in mouse uterus during peri-implantation. Acta Zoologica Sinica[J]. 2004, 50(1): 55-61, [118] Wang, HM, Li, QL, Lin, HY, Yu, XD, Qian, D, Dai, JJ, Duan, EK, Zhu, C. Expression of vascular endothelial growth factor and its receptors in the rhesus monkey (Macaca mulatta) endometrium and placenta during early pregnancy. MOLECULAR REPRODUCTION AND DEVELOPMENT[J]. 2003, 65(2): 123-131, http://ir.***.ac.cn/handle/000000/9774.
[119] 林海燕, 王红梅, 祝诚. 转化生长因子—β信号传导的Smad通路. 中国科学：C辑[J]. 2003, 33(2): 97-109, http://lib.cqvip.com/Qikan/Article/Detail?id=8077790.
[120] 林海燕, 王红梅, 祝诚. 转化生长因子—β信号传导的Smad通路. 中国科学：C辑[J]. 2003, 33(2): 97-109, http://lib.cqvip.com/Qikan/Article/Detail?id=8077790.
[121] 林海燕, 王红梅, 祝诚. 泛素－蛋白水解酶复合体通路对Smad通路的调节. 国外医学：分子生物学分册[J]. 2003, 25(4): 203-206, http://lib.cqvip.com/Qikan/Article/Detail?id=8211826.
[122] 林海燕, 王红梅, 祝诚. 转化生长因子—β对基质金属蛋白酶及其组织抑制因子调控的研究进展. 生物化学与生物物理进展[J]. 2003, 30(1): 7-12, http://lib.cqvip.com/Qikan/Article/Detail?id=7652998.
[123] 于晓光, 罗文祥, 王红梅, 邵龙江, 倪江, 祝诚. 基质金属蛋白酶—2，—9及其组织抑制物TIMPs mRNA在大鼠黄体中的表达及调节. 科学通报[J]. 2002, 47(2): 134-138, http://lib.cqvip.com/Qikan/Article/Detail?id=5982403.
[124] Wang, HM, Song, CC, Duan, CW, Shi, WX, Li, CX, Chen, DY, Wang, YC. Effects of ubiquitin-proteasome pathway on mouse sperm capacitation, acrosome reaction and in vitro fertilization. CHINESE SCIENCE BULLETIN[J]. 2002, 47(2): 127-132, http://ir.***.ac.cn/handle/000000/9750.
[125] 李庆雷, 王红梅, 林海燕, 邵龙江, 倪江, 段恩奎, 祝诚. 血管内皮生长因子在妊娠及产后大鼠卵巢中的表达. 中国科学：C辑[J]. 2002, 32(2): 131-137, http://lib.cqvip.com/Qikan/Article/Detail?id=6208722.
[126] 钱东, 王红梅, 林海燕, 张璇, 李庆雷, 刘冬林, 刘国艺, 祝诚. 泛素—蛋白水解酶复合体通路对小鼠围植入期子宫血管内皮生长因子及其受体表达的影响. 科学通报[J]. 2002, 47(24): 1883-1888, http://lib.cqvip.com/Qikan/Article/Detail?id=7288098.
[127] 李庆雷, 王红梅. 血管内皮生长因子在妊娠及产后大鼠卵巢中的表达. 中国科学：C辑[J]. 2002, 32(2): 131-137, http://lib.cqvip.com/Qikan/Article/Detail?id=6208722.
[128] 张璇, 王红梅, 林海燕, 李庆雷, 刘冬林, 钱东, 刘国艺, 祝诚. 一氧化氮对小鼠胚胎植入的调控. 科学通报[J]. 2002, 47(13): 1013-1017, http://lib.cqvip.com/Qikan/Article/Detail?id=6584135.
[129] 郭文萍, 陈贵安, 祝成, 王红梅. 基质金属蛋白酶及其组织抑制因子在子宫内膜癌中的表达及其意义. 中华妇产科杂志[J]. 2002, 37(10): 604-607, http://lib.cqvip.com/Qikan/Article/Detail?id=6963690.
[130] Wang, HM, Li, QL, Shao, LJ, Zhu, C. Expression of matrix metalloproteinase-2,-9,-14, and tissue inhibitors of metalloproteinase-1,-2,-3 in the endometrium and placenta of rhesus monkey (Macaca mulatta) during early pregnancy. BIOLOGY OF REPRODUCTION[J]. 2001, 65(1): 31-40, http://ir.***.ac.cn/handle/000000/9731.
[131] 李庆雷, 王红梅. 血管内皮生长因子在妊娠及产后大鼠卵巢中的表达. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 29-29, http://lib.cqvip.com/Qikan/Article/Detail?id=5634421.
[132] 段崇文, 王永潮, 宋长城, 李存玺, 石伟先, 陈大元, 王红梅. 泛素-蛋白水解酶复合体通路在小鼠精子体外获能、顶体反应及穿卵中的作用. 科学通报. 2001, 46(18): 1541-, [133] 李庆雷, 祝诚, 邵龙江, 倪江, 王红梅, 于晓光. 基质金属蛋白酶—2，—9及其组织抑制因子在恒河猴黄体中的表达. 科学通报[J]. 2001, 46(6): 481-, http://lib.cqvip.com/Qikan/Article/Detail?id=5043530.
[134] 王红梅, 宋长城. 泛素－蛋白水解酶复合体通路在小鼠精子体外获能、顶体反应及穿卵中的应用. 科学通报[J]. 2001, 46(18): 1541-1546, http://lib.cqvip.com/Qikan/Article/Detail?id=5868066.
[135] 王红梅. 泛素—蛋白水解酶复合体通路对小鼠胚胎植入的影响及其可能的调控机制. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 83-83, http://lib.cqvip.com/Qikan/Article/Detail?id=5634467.
[136] 王红梅, 李庆雷. MMP—2，—9，—14及TIMP—1，—2，—3在妊娠早期恒河猴子宫内膜和胎盘中的表达定位. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 87-87, http://lib.cqvip.com/Qikan/Article/Detail?id=5634471.
[137] 张璇, 王红梅. 一氧化氮在胚胎植入中的作用机理研究初探. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 81-81, http://lib.cqvip.com/Qikan/Article/Detail?id=5634465.
[138] 邵龙东, 王红梅. 基质金属蛋白酶（MMPs）与子宫内膜血管的发生. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 73-73, http://lib.cqvip.com/Qikan/Article/Detail?id=5634457.
[139] 王红梅, 李庆雷. 泛素结合蛋白在恒河猴妊娠早期子宫内膜及胎盘中的表达. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 71-71, http://lib.cqvip.com/Qikan/Article/Detail?id=5634455.
[140] 邵龙江, 王红梅. 大鼠子宫内膜的血管发生与胚胎植入. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 94-94, http://lib.cqvip.com/Qikan/Article/Detail?id=5634477.
[141] 李庆雷, 王红梅. 基质金属蛋白酶—2，—9及其组织抑制因子在恒河猴黄体中的表达. 发育与生殖生物学报：英文版[J]. 2001, 10(B10): 26-26, http://lib.cqvip.com/Qikan/Article/Detail?id=5634419.
[142] 段恩奎, 祝诚, 邵龙江, 王红梅. 围植入期大鼠子宫中血管内皮生长因子的表达与血管生成. 科学通报[J]. 2001, 46(5): 397-, http://lib.cqvip.com/Qikan/Article/Detail?id=4997285.
[143] Fu Jiejun, Lv Xiaoyin, Lin Haiyan, Wu Liang, Wang Rui, Zhou Zhi, Zhang Baohua, Wang Yan-Ling, Tsang Benjamin K., Zhu Cheng, Wang Hongmei. Ubiquitin Ligase Cullin 7 Induces Epithelial-Mesenchymal Transition in Human Choriocarcinoma Cells *. The Journal of Biological Chemistry. 285(14): 10870-10879, http://dx.doi.org/10.1074/jbc.M109.004200.

   

（ 1 ） 妊娠及妊娠相关性疾病, 负责人, 国家任务, 2013-01--2016-12
（ 2 ） 胎盘发育调控障碍与复发流产和子痫前期的发病机制, 参与, 国家任务, 2016-01--2019-12
（ 3 ） 基于干细胞的生育力维持与重建, 负责人, 国家任务, 2017-07--2021-12
（ 4 ） 生殖器官体外再造及生命孕育, 负责人, 中国科学院计划, 2017-12--2022-11
（ 5 ） 女性生殖衰老干细胞干预基础及临床队列研究, 负责人, 中国科学院计划, 2017-01--2019-12
（ 6 ） 基于声表面波的循环胎儿滋养层细胞富集系统, 负责人, 中国科学院计划, 2019-01--2020-12
（ 7 ） Circulating fetal trophoblast cells (CFTCs) and their prospects to monitor the outcomes and pregnancy process, 负责人, 企业委托, 2018-03--2021-08
（ 8 ） Identification of placenta-specifically expressed proteins or peptides, 负责人, 企业委托, 2017-04--2022-10
（ 9 ） 早期胚胎发育与不良妊娠结局, 负责人, 国家任务, 2022-01--2026-12
（ 10 ） 空间胚胎发育与生命孕育, 负责人, 中国科学院计划, 2022-06--2025-05

（1）A study on the primate embryonic and extraembryonic development   2022-02-23
（2）Deciphering the mechanisms of how primates are formed   2021-12-02
（3）灵长类动物生育力重塑及妊娠建立与维持研究   第九届灵长类生物医学研讨会   2021-09-11
（4）卵巢衰老的分子研究进展   第八届生殖健康与围产期干预技术高峰论坛   2021-07-03
（5）Comparative Early Development：Deciphering the Mechanisms of how primates are formed.   2021-06-24
（6）无（访谈答疑形式）   Science Cafe’in China第三期“《科学》咖啡沙龙”   2021-02-26
（7）Deciphering the Secrets of How Primates Are Formed   中国干细胞第十届年会   2020-10-13
（8）胎盘滋养层的发育与谱系分化   第一届母胎医学科学研究大会   2019-12-01
（9）Deciphering the secrets of how primates are formed   2019-11-12
（10）New cell subtypes and functions of the human placenta   2019-06-01
（11）Cell fate determination in the human placenta   苏州冷泉港亚洲国际会议：人类胎盘细胞命运决定   2018-11-08
（12）Cell fate determination on the feto-maternal interface and the pregnancy outcome   第五届SKLRB生殖生物学前沿国际研讨会   2018-11-03
（13）输卵管病变建模设想   第四届全国生殖外科与输卵管大会暨2018生殖外科手术与进展研讨会   2018-09-14
（14）Syncytiotrophoblast of the Human Placenta and the Pregnancy Outcome   2018-08-31
（15）胚胎植入与胎盘发育   中国医师协会妇产科医师分会母胎医学专委会第三届母胎医学大会   2018-07-06
（16）Human placental syncytialization: from the very first fusion event to the largest syncytia   2017 ASCB | EMBO Meeting   2017-12-01
（17）无   生殖研究学会第50届年会（SSR2017）   2017-07-14
（18）Session主席；Molecular mechanims guiding human trophoblast differentiation   第三届SKLRB生殖生物学前沿国际研讨会   2016-10-24
（19）Session主席   2016年国际生理学学术大会   2016-09-25
（20）无   国际胎盘干细胞协会：第三届干细胞会议   2016-09-18
（21）无   中国干细胞第六届年会   2016-09-07
（22）无   第三届蛋白质介导的膜塑形与重装国际学术研讨会   2016-05-19
（23）随同白院长代表团一行应邀参加中国科学院和渥太华大学10周年签署合作纪念活动。随后前往多伦多UHN Princess Margaret Cancer Centre进行合作访问。   中国科学院和渥太华大学10周年合作计划活动并开展胎盘发生与肿瘤干细胞合作讨论   2015-09-20
（24）无   2015第48届北美生殖生物学（SSR）年会并开展生殖免疫及相关疾病研究计划进展讨论   2015-06-17
（25）大会主席   第三届SKLRB生殖生物学前沿国际研讨会   王红梅   2014-10-26
（26）无   2014年生殖生物学／生殖医学国家重点实验室学术委员会联合会议暨第三届＂双京论坛＂   无   2014-05-15
（27）Differentiation of human trophoblast cells andcomplications of human pregnancy；   妇女的生殖健康研究国际研讨会及胚胎着床及妊娠相关疾病合作研究讨论会   王红梅   2014-04-10
（28）PLAC8 is a new marker for human placental extravillous cytotrophoblast cells (EVTs)   2013 年中国动物学会生殖生物学分会第十四次学术交流会   昌文林   2013-11-27
（29）Trophoblast fusion: Implications from live-cell imaging   王红梅   2013-11-03
（30）Trophoblast fusion: Implications from live-cell imaging   EMBO细胞和细胞融合研讨会：第41届Aharon Katzir-Katchalsky 国际会议以及以色列胎盘协会第三届年会   王红梅   2013-11-03
（31）无   无   2013-05-16
（32）PI自我介绍   生殖生物学和生殖医学国家重点实验室双京论坛   王红梅   2012-10-18
（33）无   王蕊、吕晓寅   2012-09-17
（34）无   2012年度“中加健康研究合作计划项目”联合评审会   无   2012-09-09
（35）Revealing the Hidden Puzzles of Human Syncytialization    第二届SKLRB生殖生物学国际研讨会   wanghm   2012-05-06
（36）无   2011年国际生物材料和蛋白质翻译生物修饰研讨会   无   2011-05-28
（37）Syncytialization of human trophoblast   第二届国际生殖免疫学大会(上海 2010)   王红梅   2010-11-01
（38）无   王红梅   2010-07-01
（39）Ubiquitin Ligase Cullin 7 Induces Epithelial-Mesenchymal Transition in Human Choriocarcinoma Cells   首届SKLRB围植入生物学国际研讨会   王红梅   2010-05-08

已指导学生

李闯  硕士研究生  071008-发育生物学  

周智  博士研究生  071008-发育生物学  

吴亮  博士研究生  071008-发育生物学  

付杰军  博士研究生  071003-生理学  

赵坤庆  博士研究生  071008-发育生物学  

张保华  博士研究生  071003-生理学  

吕晓寅  博士研究生  071008-发育生物学  

刘素梅  硕士研究生  071008-发育生物学  

崔丽娜  博士研究生  071008-发育生物学  

刘丹丹  博士研究生  071008-发育生物学  

王蕊  博士研究生  071008-发育生物学  

郑茹  博士研究生  071008-发育生物学  

黄幸  硕士研究生  071008-发育生物学  

范强  硕士研究生  071008-发育生物学  

刘亚伟  博士研究生  0710J6-再生医学  

蒋祥祥  博士研究生  0710J6-再生医学  

郭珊珊  博士研究生  0710J6-再生医学  

崔航  硕士研究生  0710J6-再生医学  

翟晶磊  博士研究生  1001J6-再生医学  

于偌萱  博士研究生  1001J6-再生医学  

马骄  博士研究生  1001J6-再生医学  

王一名  博士研究生  1001J6-再生医学  

戎音  硕士研究生  1001J6-再生医学  

陈烁  硕士研究生  1001J6-再生医学  

吴昊  博士研究生  1001J6-再生医学  

现指导学生

陈岗  博士研究生  1001J6-再生医学  

吴绪伦  博士研究生  1001J6-再生医学  

余带男  博士研究生  1001J6-再生医学  

赵岩  博士研究生  1001J6-再生医学  

王越  博士研究生  1001J6-再生医学  

涂婉  硕士研究生  0710J6-再生医学  

孙润  博士研究生  1001J6-再生医学  

赵文涛  硕士研究生  0710J6-再生医学  

于坤元  硕士研究生  0710J6-再生医学  

徐艳红  博士研究生  1001J6-再生医学  

何北佳  硕士研究生  071009-细胞生物学