基本信息
岳建民  男  博导  中国科学院上海药物研究所
email: jmyue@simm.ac.cn
address: 上海祖冲之路555号
postalCode: 201203

招生信息

   
招生专业
100701-药物化学
招生方向
天然药物化学
天然有机化学

教育背景

1984-08--1990-07   兰州大学化学系   理学博士
1980-09--1984-07   兰州大学化学系   理学学士

工作经历

   
工作简历
1999-05~现在, 中国科学院上海药物研究所天然药物化学研究所, 研究员
1996-05~1999-04,中国科学院上海有机化学研究所与联合利华联合实验室, 高级研究员和项目主管
1994-10~1996-04,中国科学院昆明植物研究所, 副研究员
1993-08~1994-10,英国 Bristol大学化学学院, 博士后
1991-03~1993-08,中国科学院昆明植物研究所, 博士后
1984-08~1990-07,兰州大学化学系, 理学博士
1980-09~1984-07,兰州大学化学系, 理学学士
社会兼职
2014-05-01-今,Journal of Chinese Pharmaceutical Sciences, 编委
2014-01-01-今,Natural Products and Bioprospecting, 副主编
2013-08-01-今,《中国天然药物》, 编委
2013-06-01-今,Journal of Asian Natural Products Research, 编委
-今,

专利与奖励

   
奖励信息
(1) 国家自然科学二等奖, 二等奖, 国家级, 2013
(2) 上海市自然科学一等奖, 一等奖, 省级, 2010
专利成果
( 1 ) (E)-1-(3,5-二甲氧基苯基)-2-(3,5-二羟基-4-甲氧基苯基)乙烯及其制备方法和用途, 2010, 第 1 作者, 专利号: 201010022468.2

( 2 ) 一类呋喃香豆素类化合物及其用途, 2009, 第 1 作者, 专利号: 200910200178.X

( 3 ) 呋喃香豆素类化合物在制备药物中的新用途, 2009, 第 1 作者, 专利号: 200910200179.4

( 4 ) 高良姜提取物及其用途, 2007, 第 1 作者, 专利号: ZL 200510024892.X

( 5 ) 二苯基庚酮类化合物的组合物及它的用途, 2007, 第 1 作者, 专利号: ZL 200510024890.0

( 6 ) 土槿皮酸类衍生物及其制备方法和用途, 2006, 第 1 作者, 专利号: ZL 01126479.9

( 7 ) 补骨脂抗幽门螺旋杆菌感染及治疗相关性疾病的应用, 2006, 第 1 作者, 专利号: ZL 02145323.3

( 8 ) Pseudolaric acid-B derivatives, their preparation and pharmaceutical compostions, 2005, 第 1 作者, 专利号: US 6,887,895 B2

出版信息

   
发表论文
(1) Cascarinoids A-C, a Class of Diterpenoid Alkaloids with Unpredicted Conformations from Croton cascarilloides, ORGANIC LETTERS, 2018, 通讯作者
(2) Structural Elucidation and Bioinspired Total Syntheses of Ascorbylated Diterpenoid Hongkonoids A-D, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 通讯作者
(3) Fortunoids A−C, Three Sesquiterpenoid Dimers with Different Carbon Skeletons from Chloranthus fortune, Organic Letters, 2017, 通讯作者
(4) Phainanolide A, Highly Modified and Oxygenated Triterpenoid with Unique Motifs from Phyllanthus hainanensis, Organic Letters, 2017, 通讯作者
(5) Mannolides A-C with an Intact Diterpenoid Skeleton Providing Insights on the Biosynthesis of Antitumor Cephalotaxus Troponoids, ORGANIC LETTERS, 2016, 通讯作者
(6) Cipacinoids A-D, Four Limonoids with Spirocyclic Skeletons from Cipadessa cinerascens, ORGANIC LETTERS, 2016, 通讯作者
(7) Himalensines A and B, Alkaloids with Unprecedented Carbon Skeletons from Daphniphyllum himalense, Organic Letters, 2016, 通讯作者
(8) Ciliatonoids A and B, Two Limonoids from Toona ciliate, Organic Letters, 2016, 通讯作者
(9) Phainanoids A-F, A New Class of Potent Immunosuppressive Triterpenoids with an Unprecedented Carbon Skeleton from Phyllanthus hainanensis, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2015, 通讯作者
(10) Flueggether A and Virosinine A, Anti-HIV Alkaloids from Flueggea virosa, ORGANIC LETTERS, 2015, 通讯作者
(11) Organic Carbonates from Natural Sources, CHEMICAL REVIEWS, 2014, 通讯作者
(12) Aphadilactones A-D, Four Diterpenoid Dimers with DGAT Inhibitory and Antimalarial Activities from a Meliaceae Plant, JOURNAL OF ORGANIC CHEMISTRY, 2014, 通讯作者
(13) Logeracemin A, an Anti-HIV Daphniphyllum Alkaloid Dimer with a New Carbon Skeleton from Daphniphyllum longeracemosum, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 第 1 作者
(14) Ivorenolide B, an Immunosuppressive 17-Membered Macrolide from Khaya ivorensis: Structural Determination and Total Synthesis, ORGANIC LETTERS, 2014, 第 10 作者
(15) Trichiconins A-C, Limonoids with New Carbon Skeletons from Trichilia connaroides, ORGANIC LETTERS, 2014, 通讯作者
(16) Laevinoids A and B: Two Diterpenoids with an Unprecedented Backbone from Croton laevigatus, ORGANIC LETTERS, 2013, 通讯作者
(17) Fluevirosines A-C: a biogenesis inspired example in the discovery of new bioactive scaffolds from Flueggea virosa., ORGANIC LETTERS, 2013, 通讯作者
(18) Walsucochinoids A and B: Novel Rearranged Limonoids from Walsura cochinchinensis, Organic Letters, 2012, 通讯作者
(19) Ivorenolide A, an Unprecedented Immunosuppressive Macrolide from Khaya ivorensis: Structural Elucidation and Bioinspired Total Synthesis, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2012, 第 1 作者
(20) Potent HGF/c-Met Axis Inhibitors from Eucalyptus globules: the Coupling of Phloroglucinol and Sesquiterpenoid Is Essential for the Activity, Journal of Medicinal Chemistry, 2012, 通讯作者
(21) Chukrasones A and B: Potential Kv1.2 Potassium Channel Blockers with New Skeletons from Chukrasia tabularis, ORGANIC LETTERS, 2012, 通讯作者
(22) Serratustones A and B Representing a New Dimerization Pattern of Two Types of Sesquiterpenoids from Chloranthus serratus, ORGANIC LETTERS, 2012, 通讯作者
(23) Meliarachins A-K: Eleven Limonoids from the Twigs and Leaves of Melia azedarach, HELVETICA CHIMICA ACTA, 2011, 通讯作者
(24) Phragmalin-Type Limonoid Orthoesters from the Twigs of Swietenia macrophylla, CHEMICAL & PHARMACEUTICAL BULLETIN, 2011, 通讯作者
(25) Ring A-seco triterpenoids with antibacterial activity from Dysoxylum hainanense, BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 通讯作者
(26) Sarcanolides A and B: two sesquiterpenoid dimers with a nonacyclic scaffold from Sarcandra hainanensis, TETRAHEDRON, 2011, 通讯作者
(27) Daphnane-Type Diterpenoids from Trigonostemon howii, JOURNAL OF NATURAL PRODUCTS, 2011, 通讯作者
(28) Aphanamolide A, a New Limonoid from Aphanamixis polystachya, ORGANIC LETTERS, 2011, 通讯作者
(29) Onoceranoid-Type Triterpenoids from Lansium domesticum, JOURNAL OF NATURAL PRODUCTS, 2011, 通讯作者
(30) Limonoids and Diterpenoids from Toona ciliata Roem. var. yunnanensis, PLANTA MEDICA, 2011, 通讯作者
(31) Trigoxyphins A-G: Seven Diterpenes from Trigonostemon xyphophylloides, Journal of Natural Products, 2010, 通讯作者
(32) Mesendanins A–J:Ten Limonoids from the Twigs and Leaves of Melia toosendan, Journal of Natural Products, 2010, 通讯作者
(33) Sesquiterpenes and Dimeric Sesquiterpenoids from Sarcandra glabra, JOURNAL OF NATURAL PRODUCTS, 2010, 通讯作者
(34) Limonoids and Triterpenoids from Khaya senegalensis, JOURNAL OF NATURAL PRODUCTS, 2010, 通讯作者
(35) Mulavanins A–E: Limonoids from Munronia delavayi, PHYTOCHEMISTRY, 2010, 通讯作者
(36) Structure Determination of Grandifotane A from Khaya grandifoliola by NMR, X-ray Diffraction, and ECD Calculation, ORGANIC LETTERS, 2010, 通讯作者
(37) Multistalides A and B, two novel sesquiterpenoid dimers from Chloranthus multistachys, TETRAHEDRON LETTERS, 2010, 通讯作者
(38) Trigochinins A-C: Three Novel Daphnane-type Diterpenes from Trigonostemon chinensis, Organic Letters, 2010, 通讯作者
(39) Trigochinins D–I: six new daphnane-type diterpenoids from Trigonostemon chinensis, TETRAHEDRON, 2010, 通讯作者
(40) Three New Terpenoids from Pinus yunnanensis, HELVETICACHIMICAACTA, 2010, 通讯作者
(41) Two Limonoids, Khayalenoids, A and B with an Unprecedented 8-Oxa-tricyclo4.3.2.0(2,7)undecane Motif, from Khaya senegalensis, ORGANIC LETTERS, 2009, 通讯作者
(42) Structurally Diverse Limonoids from the Fruits of Swietenia mahagoni, JOURNAL OF NATURAL PRODUCTS, 2009, 通讯作者
(43) Harrisotones A–E, five novel prenylated polyketides with a rare spirocyclic skeleton from Harrisonia perforata, TETRAHEDRON, 2009, 通讯作者
(44) Limonoids from Khaya ivorensis, PHYTOCHEMISTRY, 2009, 通讯作者
(45) Cinnacassides A-E, five geranylphenylacetate glycosides from Cinnamomum cassia, TETRAHEDRON, 2009, 通讯作者
(46) Calycinumines A and B, Two Novel Alkaloids from Daphniphyllum calycinum, ORGANIC LETTERS, 2009, 通讯作者
(47) Plant Orthoesters, CHEMICAL REVIEWS, 2009, 通讯作者
(48) D-Ring-Opened Phragmalin-Type Limonoid Orthoesters from the Twigs of Swietenia macrophylla, JOURNAL OF NATURAL PRODUCTS, 2009, 通讯作者
(49) Ring-A Modified Triterpenoids from Dysoxylum hainanense, 2009, 通讯作者
(50) Trigochilides A and B, Two Highly Modified Daphnane-Type Diterpenoids from Trigonostemon chinensis, ORGANIC LETTERS, 2009, 通讯作者
(51) Chisiamols A-F,Triterpenoids from Chisocheton siamensis, CHINESE JOURNAL OF CHEMISTRY, 2009, 第 4 作者
(52) Alkaloids from the Leaves of Daphniphyllum subverticillatum, JOURNAL OF NATURAL PRODUCTS, 2009, 通讯作者

科研活动

   
科研项目
( 1 ) 新骨架重要活性天然分子的发现与功能研究, 负责人, 国家任务, 2016-01--2020-12
( 2 ) 基于清热解毒重要傣药的新型活性物质的发现与研究, 负责人, 国家任务, 2014-01--2017-12
( 3 ) 新墨西哥交酯型柠檬苦素类衍生物的发现与功能研究, 负责人, 国家任务, 2014-01--2016-12
( 4 ) 人工细胞的代谢网络改造与系统优化, 负责人, 国家任务, 2012-01--2016-08
参与会议
(1)新颖结构活性天然物质的发现与研究   第十一届全国天然有机化学会议   2016-09-27
(2)重要活性天然化合物的发现与研究   中国化学会第十届全国天然有机化学学术会   2014-11-25
(3)Structurally Diverse and Biologically Important Compounds from Chinese Medicinal Plants   2014-10-20
(4)具有生物活性的新颖结构天然产物发现及其功能   第九届全国天然有机化学学术会议   2012-11-08
(5)复杂结构活性天然化合物的发现与研究   中国化学会第28届学术年会   2012-04-13