基本信息
徐旭东  男  博导  中国科学院水生生物研究所
电子邮件: xux@ihb.ac.cn
通信地址: 武昌东湖南路7号中科院水生所
邮政编码: 430072

招生信息

   
招生专业
071007-遗传学
招生方向
藻类遗传学

教育背景

1986-09--1991-07   中国科学院水生生物研究所   博士

工作经历

   
工作简历
1999-09~现在, 中国科学院水生生物研究所, 研究员
1986-09~1991-07,中国科学院水生生物研究所, 博士

专利与奖励

   
奖励信息
(1) “万人计划”百千万工程领军人才, 国家级, 2014
(2) 百千万人才工程国家级人选, 国家级, 2009
(3) 中国青年科技奖, , 国家级, 1994
(4) 高效灭蚊蚴转基因蓝藻的研究, 一等奖, 省级, 1993
专利成果
( 1 ) 用于促进集胞藻分泌氨基酸的培养基、培养方法和藻株, 2020, 第 1 作者, 专利号: ZL 2017 1 0651573.4

( 2 ) 硅藻工程藻株及其制备方法、应用, 2019, 第 2 作者, 专利号: ZL 2014 1 0409293.9

( 3 ) 一种链带藻NMX451的获得和遗传转化的方法, 2016, 第 2 作者, 专利号: ZL 2013 1 0407874.4

( 4 ) 产油单针藻LB50的获得及应用, 2015, 第 2 作者, 专利号: ZL 2013 1 0426399.5

( 5 ) 产油单针藻LB59的获得及应用, 2015, 第 2 作者, 专利号: ZL 2013 1 0428561.7

( 6 ) 一种利于收获的蓝藻的基因转移方法, 2005, 第 1 作者, 专利号: ZL 00 1 28152.6

出版信息

   
发表论文
(1) Effects of PatU3 Peptides on Cell Size and Heterocyst Frequency of Anabaena sp. Strain PCC 7120, JOURNAL OF BACTERIOLOGY, 2021, 第 5 作者
(2) Early Stage Adaptation of a Mesophilic Green Alga to Antarctica: Systematic Increases in Abundance of Enzymes and LEA Proteins, MOLECULAR BIOLOGY AND EVOLUTION, 2020, 通讯作者
(3) Expression from DIF1-motif promoters of hetR and patS is dependent on HetZ and modulated by PatU3 during heterocyst differentiation, PLOS ONE, 2020, 通讯作者
(4) Effects of a Type I RM System on Gene Expression and Glycogen Catabolism in Synechocystis sp. PCC 6803, FRONTIERS IN MICROBIOLOGY, 2020, 通讯作者
(5) Cyanophage A-1(L) Adsorbs to Lipopolysaccharides of Anabaena sp. Strain PCC 7120 via the Tail Protein Lipopolysaccharide-Interacting Protein (ORF36), JOURNAL OF BACTERIOLOGY, 2019, 通讯作者
(6) Functional Overlap of hetP and hetZ in Regulation of Heterocyst Differentiation in Anabaena sp Strain PCC 7120, JOURNAL OF BACTERIOLOGY, 2018, 通讯作者
(7) Three substrains of the cyanobacterium Anabaena sp. PCC 7120 display divergence in genomic sequences and hetC function, Journal of Bacteriology, 2018, 通讯作者
(8) Processing of PatS, a morphogen precursor, in cell extracts of Anabaena sp PCC 7120, FEBS LETTERS, 2017, 通讯作者
(9) Autumnal increase in proportion of toxic Microcystis in Lake Taihu depends more on temperature adaptability than on effects of toxigenicity, JOURNAL OF APPLIED MICROBIOLOGY, 2015, 
(10) The HetR-binding site that activates expression of patA in vegetative cells is required for normal heterocyst patterning in Anabaena sp. PCC 7120, SCIENCE BULLETIN, 2015, 通讯作者
(11) Unraveling the genome structure of cyanobacterial podovirus A-4L with long direct terminal repeats, VIRUS RESEARCH, 2015, 第 4 作者
(12) Role of Spermidine in Overwintering of Cyanobacteria, JOURNAL OF BACTERIOLOGY, 2015, 通讯作者
(13) Efficacy of a dual fluorescence method in detecting the viability of overwintering cyanobacteria, LETTERS IN APPLIED MICROBIOLOGY, 2013, 
(14) Role of two phosphohexomutase genes in glycogen synthesis in Synechocystis sp. PCC6803, Chinese Science Bulletin, 2013, 
(15) Effects of Rbp3 on lipid peroxidation and salt tolerance in Synechocystis sp. PCC 6803, FEBS LETTERS, 2013, 通讯作者
(16) RNase III-dependent down-regulation of ftsH by an artificial internal sense RNA in Anabaena sp PCC 7120, FEMS MICROBIOLOGY LETTERS, 2013, 通讯作者
(17) The cyanobacterial NAD kinase gene sll1415 is required for photoheterotrophic growth and cellular redox homeostasis in Synechocystis sp. PCC 6803, Journal of Bacteriology, 2012, 通讯作者
(18) Identification of a novel thylakoid protein gene involved in cold acclimation in cyanobacteria, MICROBIOLOGY-SGM, 2012, 通讯作者
(19) A high sensitivity iron-dependent bioreporter used to measure iron bioavailability in freshwaters, FEMS MICROBIOLOGY LETTERS, 2012, 第 2 作者
(20) Molecular cloning and functional analyses of glutathione peroxidase homologous genes from Chlorella sp., Gene, 2012, 通讯作者
(21) Identification of the HetR Recognition Sequence Upstream of hetZ in Anabaena sp Strain PCC 7120, JOURNAL OF BACTERIOLOGY, 2012, 通讯作者
(22) A small internal antisense RNA (aftsH) of all3642 (ftsH) in Anabaena sp PCC 7120, CHINESE SCIENCE BULLETIN, 2012, 通讯作者
(23) Identification and characterization of genes encoding two novel LEA proteins in Antarctic and temperate strains of Chlorella vulgaris, GENE, 2011, 通讯作者
(24) Role of Rbp1 in the Acquired Chill-Light Tolerance of Cyanobacteria ▿ †, JOURNAL OF BACTERIOLOGY, 2011, 通讯作者
(25) Characterization of the tandem-arrayed hiC6 genes in Antarctic and temperate strains of Chlorella vulgaris, FEMS MICROBIOLOGY LETTERS, 2011, 通讯作者
(26) Effects of a type-II RNA-binding protein on fatty acid composition in Synechocystis sp. PCC 6803, CHINESE SCIENCE BULLETIN, 2010, 通讯作者
(27) The N-Acetylmuramic Acid 6-Phosphate Etherase Gene Promotes Growth and Cell Differentiation of Cyanobacteria under Light-Limiting Conditions, JOURNAL OF BACTERIOLOGY, 2010, 第 3 作者
(28) CalA, a cyAbrB protein, binds to the upstream region of ftsZ and is down-regulated in heterocysts in Anabaena sp PCC 7120, ARCHIVES OF MICROBIOLOGY, 2010, 通讯作者
(29) Depletion of Vipp1 in Synechocystis sp. PCC 6803 affects photosynthetic activity prior to the loss of thylakoid membranes, FEMS Microbiology Letters, 2009, 通讯作者
(30) alpha-tocopherol is essential for acquired chill-light tolerance (ACLT) in the cyanobacterium Synechocystis sp. PCC 6803, Journal of Bacteriology, 2008, 通讯作者
(31) A gene cluster that regulates both heterocyst differentiation and pattern formation in Anabaena sp strain PCC 7120, MOLECULAR MICROBIOLOGY, 2007, 通讯作者
(32) Identification of a gene, ccr-1 (sll1242), required for chill-light tolerance and growth at 15oC in Synechocystis sp. PCC 6803, Microbiology-SGM, 2007, 通讯作者
(33) Predicted glycosyl transferase geneslocated outside of the HEP island are required for formation of heterocyst envelope polysaccharide in Anabaena sp. strain PCC 7120, Journal of Bacteriology, 2007, 通讯作者
(34) Regulation by hetC of genes required for heterocyst differentiation and cell division in Anabaena sp strain PCC 7120, JOURNAL OF BACTERIOLOGY, 2005, 
(35) alr0117, a two-component histidine kinase gene, is involved in heterocyst development in Anabaena sp PCC 7120, MICROBIOLOGY-SGM, 2004, 

科研活动

   
科研项目
( 1 ) hetZ基因调节丝状固氮蓝细菌细胞分化的机理, 负责人, 国家任务, 2013-01--2016-12
( 2 ) 优良特色藻种的筛选和评价体系研究, 参与, 国家任务, 2014-01--2016-12
( 3 ) 集胞蓝细菌RNA结合蛋白Rbp3的转录后调控功能, 负责人, 国家任务, 2015-01--2018-12
( 4 ) 利用微藻消除石化企业NOx尾气生产高值产品的技术研发与示范, 负责人, 中国科学院计划, 2016-01--2017-12
( 5 ) 工业烟气的微藻生物转化, 负责人, 地方任务, 2017-08--2020-08
( 6 ) 丝状产异形胞固氮蓝细菌中成形素小肽的加工和扩散, 负责人, 国家任务, 2018-01--2021-12
( 7 ) 人工噬藻体的设计、合成和拯救, 参与, 国家任务, 2019-01--2024-01
( 8 ) 微藻基因组简化重组的技术开发和规律认识, 负责人, 国家任务, 2021-12--2026-11