Highly selective separation and analysis of biological compounds

Design, screening and application of peptide probes

 Dynamic interaction of biomolecules

1984.7, B.Sc., Beijing Normal University

1997.7, M.Sc., Institute of Chemistry, CAS

2005.2, Ph.D., Graduate University of CAS

1993-1995 Peptide Institute, Japan, Visiting Scientist

1999.12-2000.1 Institute for Protein Research, Osaka University, Japan, Visiting Scientist

   

1986-now Institute of Chemistry, CAS, Research Associate,  Associate Professor, Research Professor

   

         Q. Zhang, Y. Huang, R. Zhao*, G.. Liu, Y. Chen, Determining binding sites of drugs on human serum albumin using FIA-QCM, Biosens. Bioelectron., 2008, 24: 48-54

         Y.. Huang, R. Zhao*, J. Luo, S. Xiong, D. Shangguan, H. Zhang, G. Liu, Y. Chen, Design, synthesis and screening of antisense peptide based combinatorial peptide libraries towards an aromatic region of SARS-CoV, J. Mol. Recognit., 2008, 21: 122-131

         Q. Zhang, Y. Huang, R. Zhao*, G. Liu, Y. Chen, In-situ growth of nanogold on quartz crystal microbalance and its application in the interaction between heparin and antithrombin III, J. Colloid Interface Sci., 2008, 319: 94-99

         J. Luo, Q. Zhang, Y. Huang, G. Liu, R. Zhao*, Quartz crystal microbalance biosensor for recombinant human interferon-β detection based on antisense peptide approach, Anal. Chim. Acta, 2007, 590: 91-97

         X. Liu, Z. Chen, R. Zhao*, D. Shangguan, G. Liu, Y. Chen, Uniform-sized molecularly imprinted polymer for metsulfuron-methyl by one-step swelling and polymerization method, Talanta, 2007, 71: 1205-1210

　
            X. Liu, C. Ouyang, R. Zhao*, D. Shangguan, Y. Chen, G. Liu, Monolithic molecularly imprinted polymer for sulfamethoxazole and molecular recognition properties in aqueous mobile phase, Anal. Chim. Acta, 2006, 571: 235-241

          R. Zhao*, C. Fang, X. Yu, Y. Liu, J. Luo, D. Shangguan, S. Xiong, G. Liu*, Screening of inhibitors for influenza A virus using high performance affinity chromatography and combinatorial peptide libraries, J. Chromatogr. A, 2005, 1064: 59-66

          H. Zhang, R. Zhao*, Z. Chen, D. Shangguan, G. Liu, QCM–FIA with PGMA coating for dynamic interaction study of heparin and antithrombin III, Biosens. Bioelectron., 2005, 21: 121-127

          R. Zhao*, J. Luo, D. Shangguan, G. Liu, A novel matrix for high performance affinity chromatography and its application in the purification of antithrombin III, J. Chromatogr. B, 2005, 816: 175-181
 

刘吉众  博士研究生  070302-分析化学  80032-化学研究所

谢云峰  博士研究生  070302-分析化学  80032-化学研究所

王蔚芝  博士研究生  070302-分析化学  80032-化学研究所