基本信息
叶昕  女  博导  中国科学院微生物研究所
电子邮件: yex@im.ac.cn
通信地址: 北京朝阳区北辰西路1号
邮政编码:

招生信息

   
招生专业
071010-生物化学与分子生物学
071010-生物化学与分子生物学
招生方向


教育背景

   
学历
-- 研究生
学位
-- 博士

出版信息

   
发表论文
[1] Zhang, Fang, Li, Yong, Gan, Lipeng, Tong, Xiaomei, Qi, Dandan, Wang, Qihui, Ye, Xin. HBx-upregulated MAFG-AS1 promotes cell proliferation and migration of hepatoma cells by enhancing MAFG expression and stabilizing nonmuscle myosin IIA. FASEB JOURNAL[J]. 2021, 35(5): http://dx.doi.org/10.1096/fj.202002374R.
[2] Li, Yucen, Chai, Wenjia, Min, Jie, Ye, Zhen, Tong, Xiaomei, Qi, Dandan, Liu, Wenjun, Luo, Enjie, Li, Jing, Ye, Xin. Neddylation of M1 negatively regulates the replication of influenza A virus. JOURNAL OF GENERAL VIROLOGY[J]. 2020, 101(12): 1242-1250, https://www.webofscience.com/wos/woscc/full-record/WOS:000604638400003.
[3] Li, Xinda, Guo, Guijie, Lu, Min, Chai, Wenjia, Li, Yucen, Tong, Xiaomei, Li, Jing, Jia, Xiaojuan, Liu, Wenjun, Qi, Dandan, Ye, Xin. Long Noncoding RNA Lnc-MxA Inhibits Beta Interferon Transcription by Forming RNA-DNA Triplexes at Its Promoter. JOURNAL OF VIROLOGY[J]. 2019, 93(21): [4] Qi, Dandan, Hu, Lei, Jiao, Tong, Zhang, Tinghong, Tong, Xiaomei, Ye, Xin. Phosphatase Cdc25A Negatively Regulates the Antiviral Immune Response by Inhibiting TBK1 Activity. JOURNAL OF VIROLOGY[J]. 2018, 92(19): https://www.webofscience.com/wos/woscc/full-record/WOS:000444430700026.
[5] Chai, Wenjia, Li, Jing, Shangguan, Qilin, Liu, Qi, Li, Xinda, Qi, Dandan, Tong, Xiaomei, Liu, Wenjun, Ye, Xin. Lnc-ISG20 Inhibits Influenza A Virus Replication by Enhancing ISG20 Expression. JOURNAL OF VIROLOGY[J]. 2018, 92(16): https://www.webofscience.com/wos/woscc/full-record/WOS:000440292200021.
[6] Liu, Ningning, Liu, Qi, Yang, Xiaohai, Zhang, Fang, Li, Xinda, Ma, Yuanwu, Guan, Feifei, Zhao, Xin, Li, Zhiwei, Zhang, Lianfeng, Ye, Xin. Hepatitis B Virus-Upregulated LNC-HUR1 Promotes Cell Proliferation and Tumorigenesis by Blocking p53 Activity. HEPATOLOGY[J]. 2018, 68(6): 2130-2144, https://www.webofscience.com/wos/woscc/full-record/WOS:000451622600050.
[7] Zhang, Tinghong, Ye, Zhen, Yang, Xiaohai, Qin, Yujie, Hu, Yi, Tong, Xiaomei, Lai, Wenbin, Ye, Xin. NEDDylation of PB2 Reduces Its Stability and Blocks the Replication of Influenza A Virus. SCIENTIFIC REPORTS[J]. 2017, 7: http://www.corc.org.cn/handle/1471x/2157255.
[8] 叶昕. HDM2 promotes the NEDDylation of HBV HBx and enhances its stability and functions. Journal of Virology. 2017, [9] 叶昕. MiR-33a disturbs influenza A virus replication via targeting ARCN1 and inhibiting viral vRNP activity. Journal of General Virology. 2016, [10] Liu, Ningning, Jiao, Tong, Huang, Yan, Liu, Wenjun, Li, Zhiwei, Ye, Xin. Hepatitis B Virus Regulates Apoptosis and Tumorigenesis through the MicroRNA-15a-Smad7-Transforming Growth Factor Beta Pathway. JOURNAL OF VIROLOGY[J]. 2015, 89(5): 2739-2749, https://www.webofscience.com/wos/woscc/full-record/WOS:000350207400026.
[11] Sun, Liping, Huang, Yan, Wei, Qian, Tong, Xiaomei, Cai, Rong, Nalepa, Grzegorz, Ye, Xin. Cyclin E-CDK2 Protein Phosphorylates Plant Homeodomain Finger Protein 8 (PHF8) and Regulates Its Function in the Cell Cycle. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2015, 290(7): 4075-4085, http://dx.doi.org/10.1074/jbc.M114.602532.
[12] Lei Hu, Xin Ye, Xiaomei Tong, Yetao Wang. Casein Kinase 1γ1 Inhibits the RIG-I/TLR Signaling Pathway through Phosphorylating p65 and Promoting Its Degradation. American Association of Immunologists. 2014, http://oa.las.ac.cn/oainone/service/browseall/read1?ptype=JA&workid=JA201902020965336ZK.
[13] Wei, Qian, Li, Junhui, Liu, Ting, Tong, Xiaomei, Ye, Xin. Phosphorylation of Minichromosome Maintenance Protein 7 (MCM7) by Cyclin/Cyclin-dependent Kinase Affects Its Function in Cell Cycle Regulation. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 288(27): 19715-19725, http://dx.doi.org/10.1074/jbc.M112.449652.
[14] Du, Zhaoyang, Tong, Xiaomei, Ye, Xin. Cyclin D1 Promotes Cell Cycle Progression through Enhancing NDR1/2 Kinase Activity Independent of Cyclin-dependent Kinase 4. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2013, 288(37): 26678-26687, http://dx.doi.org/10.1074/jbc.M113.466433.
[15] 叶昕. Hepatitis B virus inhibits apoptosis of hepatoma cells by sponging miR-15a/16 cluster.. Journal of Virology. 2013, [16] Wang, Yetao, Tong, Xiaomei, Li, Gang, Li, Junhui, Deng, Min, Ye, Xin. Ankrd17 positively regulates RIG-I-like receptor (RLR)-mediated immune signaling. EUROPEAN JOURNAL OF IMMUNOLOGY[J]. 2012, 42(5): 1304-1315, https://www.webofscience.com/wos/woscc/full-record/WOS:000303317700026.
[17] Zhang, Junjie, Li, Gang, Ye, Xin. Cyclin T1/CDK9 Interacts with Influenza A Virus Polymerase and Facilitates Its Association with Cellular RNA Polymerase II. JOURNAL OF VIROLOGY[J]. 2010, 84(24): 12619-12627, http://124.16.144.217/handle/311023/1399.
[18] Deng, Min, Li, Fahui, Ballif, Bryan A, Li, Shan, Chen, Xi, Guo, Lin, Ye, Xin. Identification and Functional Analysis of a Novel Cyclin E/Cdk2 Substrate Ankrd17. JOURNAL OF BIOLOGICAL CHEMISTRY[J]. 2009, 284(12): 7875-7888, http://dx.doi.org/10.1074/jbc.M807827200.
[19] Huang Yan, Sun Liping, Liu Ningning, Wei Qian, Jiang Liangzhen, Tong Xiaomei, Ye Xin. Polo-like Kinase 1 (Plk1) Up-regulates Telomerase Activity by Affecting Human Telomerase Reverse Transcriptase (hTERT) Stability *. The Journal of Biological Chemistry. 290(30): 18865-18873, http://dx.doi.org/10.1074/jbc.M114.635375.
[20] Wang Yetao, Tong Xiaomei, Omoregie Ehimwenma Sheena, Liu Wenjun, Meng Songdong, Ye Xin. Tetraspanin 6 (TSPAN6) Negatively Regulates Retinoic Acid-inducible Gene I-like Receptor-mediated Immune Signaling in a Ubiquitination-dependent Manner *. The Journal of Biological Chemistry. 287(41): 34626-34634, http://dx.doi.org/10.1074/jbc.M112.390401.
[21] Liu Ting, Deng Min, Li Junhui, Tong Xiaomei, Wei Qian, Ye Xin. Phosphorylation of Right Open Reading Frame 2 (Rio2) Protein Kinase by Polo-like Kinase 1 Regulates Mitotic Progression *. The Journal of Biological Chemistry. 286(42): 36352-36360, http://dx.doi.org/10.1074/jbc.M111.250175.

指导学生

已指导学生

李发慧  博士研究生  071010-生物化学与分子生物学  

李刚  博士研究生  071010-生物化学与分子生物学  

蔡荣  硕士研究生  071010-生物化学与分子生物学  

张军杰  博士研究生  071010-生物化学与分子生物学  

邓敏  博士研究生  071010-生物化学与分子生物学  

现指导学生

李军辉  博士研究生  071010-生物化学与分子生物学  

刘婷  博士研究生  071010-生物化学与分子生物学  

卫茜  博士研究生  071010-生物化学与分子生物学  

汪世雄  硕士研究生  071010-生物化学与分子生物学  

孙莉萍  博士研究生  071010-生物化学与分子生物学  

王烨涛  博士研究生  071010-生物化学与分子生物学  

赖文彬  硕士研究生  071010-生物化学与分子生物学  

黄艳  博士研究生  071010-生物化学与分子生物学  

姜良珍  博士研究生  071010-生物化学与分子生物学