1987-1992 Ph.D. Degree in Biochemistry, Beijing Agricultural University (BAU);

1985-1987   Assistant Lecturer in Biochemistry, Beijing Agricultural University

1987-1993   Lecturer in Biochemistry, Beijing Agricultural University

1993-1995   Associate Professor in Biochemistry, Beijing Agricultural University

1995-1999   Post-Doctoral scientist in the Babraham Institute, Cambridge, UK

1999-2000   Senior Post-Doctoral scientist in Roswell Park Cancer Institute, New York, USA

2000-2006   Assistant Scientist in Children’s Hospital Oakland Research Institute, California, USA

2006-present  Principal Investigator in Institute of Microbiology, Chinese Academy of Sciences;

             Professor in genomics at the University of Chinese Academy of Sciences

1987-1993   Lecturer in Biochemistry, Beijing Agricultural University

1993-1995   Associate Professor in Biochemistry, Beijing Agricultural University

2006-2016  Professor in Molecular Biology and  Microbial Genomics, UCAS

1.      Lingxiang Zhu · Jun Zhong · Xinmiao Jia · Guan Liu · Yu Kang · Mengxing Dong · Xiuli Zhang · Qian Li · Liya Yue · Cuidan Li · Jing Fu · Jingfa Xiao · Jiangwei Yan · Bing Zhang · Meng Lei · Suting Chen · Lingna Lv · Baoli Zhu · Hairong Huang · Fei Chen. 2015. Precision methylome characterization of Mycobacterium tuberculosis complex (MTBC) using PacBio single-molecule real-time (SMRT) technology. Nucleic Acids Research 12/2015; DOI:10.1093/nar/gkv1498.

2.      Yongfei Hu · Fei Liu · Ivan Y C Lin · George F Gao · Baoli Zhu. 2015. Dissemination of the mcr-1 colistin resistance gene. The Lancet Infectious Diseases 12/2015; DOI:10.1016/S1473-3099(15)00533-2. 

3.      Yongfei Hu · Yinghui Liu · Jing Li · Yanbin Feng · Na Lu · Baoli Zhu · Song Xue. 2015. Structural and functional analysis of a low-temperature-active alkaline esterase from South China Sea marine sediment microbial metagenomic library. Journal of Industrial Microbiology 09/2015; 42(11). 

4.      Ma Junping · Yang Xi · Lv Na · Liu Fei · Chen Yan · Zhu Baoli. 2015. Re-sequencing and assembly of chicken T cell receptor gamma locus. Hereditas (Beijing) 09/2015; 37(6):568-74.

5.      Fei Liu · Xi Yang · Zhiyun Wang · Matilda Nicklasson · Firdausi Qadri · Yong Yi · Yuying Zhu · Na Lv · Jing Li · Ruifen Zhang · Huijuan Guo · Baoli Zhu · Åsa Sjöling · Yongfei Hu. 2015. Draft genomes of four enterotoxigenic Escherichia coli (ETEC) clinical isolates from China and Bangladesh. Gut Pathogens 04/2015; 7(1):10.

6.      Chunguang Luan · Lingling Xie · Xi Yang · Huifang Miao · Na Lv · Ruifen Zhang · Xue Xiao · Yongfei Hu · Yulan Liu · Na Wu · Yuanmin Zhu · Baoli Zhu. 2015. Dysbiosis of Fungal Microbiota in the Intestinal Mucosa of Patients with Colorectal Adenomas. Scientific Reports 01/2015; 5:7980.

7.      Guo Peng · Wang Dan · Wu Jun · Yang Junjun · Ren Tong · Zhu Baoli · Xiang Yang. 2015. Transcriptome profiling of the cancer and adjacent nontumor tissues from cervical squamous cell carcinoma patients by RNA sequencing. Tumor Biology 01/2015; 36(5).

8.      Juan Pu · Shuoguo Wang · Yanbo Yin · Guozhong Zhang · Robert A. Carter · Jinliang Wang · Guanlong Xu · Honglei Sun · Min Wang · Chu Wen · [...] · Qian Wang · Qian Du · Meng Sun · Jinnan Bao · Yipeng Sun · Jixun Zhao · Hui Zhang · Gang Wu · Jinhua Liu · Robert G. Webster. 2015. Evolution of the H9N2 influenza genotype that facilitated the genesis of the novel H7N9 virus. Proceedings of the National Academy of Sciences 01/2015; 112(2):548-553.

9.      Peng Guo · Dan Wang · Jun Wu · Junjun Yang · Tong Ren · Baoli Zhu · Yang Xiang. 2015. The landscape of alternative splicing in cervical squamous cell carcinoma. OncoTargets and Therapy 01/2015; 8:73-9.

10.  Fei Liu · Yuying Zhu · Yong Yi · Na Lu · Baoli Zhu · Yongfei Hu. 2014. Comparative genomic analysis of Acinetobacter baumannii clinical isolates reveals extensive genomic variation and diverse antibiotic resistance determinants. BMC Genomics 12/2014; 15(1):1163.

11.  Yongfei Hu · Yuying Zhu · Yanan Ma · Fei Liu · Na Lu · Xi Yang · Chunguang Luan · Yong Yi · Baoli Zhu. 2014. Genomic Insights into Intrinsic and Acquired Drug Resistance Mechanisms in Achromobacter xylosoxidans. Antimicrobial Agents and Chemotherapy 12/2014; 59(2).

12.  Henan Li · Fei Liu · Yawei Zhang · Xiaojuan Wang · Chunjiang Zhao · Hongbin Chen · Feifei Zhang · Baoli Zhu · Yongfei Hu · Hui Wang. 2014. Evolution of Carbapenem-Resistant Acinetobacter baumannii Revealed through Whole-Genome Sequencing and Comparative Genomic Analysis. Antimicrobial Agents and Chemotherapy 12/2014; 59(2).

13.  Xi Yang · Di Liu · Na Lv · Fangqing Zhao · Fei Liu · Jing Zou · Yan Chen · Xue Xiao · Jun Wu · Peipei Liu · Jing Gao · Yongfei Hu · Yi Shi · Jun Liu · Ruifen Zhang · Chen Chen · Juncai Ma · George F Gao · Baoli Zhu. 2014. TCRklass: A New K-String-Based Algorithm for Human and Mouse TCR Repertoire Characterization. The Journal of Immunology 11/2014.

14.  Huifang Miao · Na Wu · Chunguang Luan · Xi Yang · Ruifen Zhang · Na Lv · Baoli Zhu. 2014. Quantitation of intestinal Fusobacterium and butyrate- producing bacteria in patients with colorectal adenomas and colorectal cancer. ACTA MICROBIOLOGICA SINICA 10/2014; 54(10):1228-34.

15.  Lucia Carbone · R. Alan Harris · Sante Gnerre · Krishna R. Veeramah · Belen Lorente-Galdos · John Huddleston · Thomas J. Meyer · Javier Herrero · Christian Roos · Bronwen Aken · [...] · Tomas Marques-Bonet · Evan E. Eichler · Lucinda Fulton · Catrina Fronick · Donna M. Muzny · Wesley C. Warren · Kim C. Worley · Jeffrey Rogers · Richard K. Wilson · Richard A. Gibbs. 2014. Gibbon genome and the fast karyotype evolution of small apes. Nature 09/2014; 513(7517):195-201.

16.  Wenbao Qi · Weifeng Shi · Wei Li · Lihong Huang · Huanan Li · Ying Wu · Jinghua Yan · Peirong Jiao · Baoli Zhu · Juncai Ma · George F Gao · Ming Liao · Di Liu. 2014. Continuous reassortments with local chicken H9N2 virus underlie the human-infecting influenza A (H7N9) virus in the new influenza season, Guangdong, China. Protein & Cell 08/2014; 5(11).

17.  Kim C Worley · Wesley C Warren · Jeffrey Rogers · Devin Locke · Donna M Muzny · Elaine R Mardis · George M Weinstock · Suzette D Tardif · Kjersti M Aagaard · Nicoletta Archidiacono · [...] · Derek E Wildman · David J Witherspoon · Rita A Wright · Yuanqing Wu · Weimin Xiao · Jinchuan Xing · Evgeny M Zdobnov · Baoli Zhu · Richard A Gibbs · Richard K Wilson. 2014. The common marmoset genome provides insight into primate biology and evolution. Nat Genet. 2014 Aug;46(8):850-7.(46):850–857.

18.  Peipei Liu · Di Liu · Xi Yang · Jing Gao · Yan Chen · Xue Xiao · Fei Liu · Jing Zou · Jun Wu · Juncai Ma · Fangqing Zhao · Xuyu Zhou · George F Gao · Baoli Zhu. 2014. Characterization of human αβTCR repertoire and discovery of D-D fusion in TCRβ chains. Protein & Cell 05/2014; 5(8).

19.  Yuying Zhu · Yong Yi · Fei Liu · Na Lv · Xi Yang · Jing Li · Yongfei Hu · Baoli Zhu. 2014. Distribution and molecular profiling of class 1 integrons in MDR Acinetobacter baumannii isolates and whole genome-based analysis of antibiotic resistance mechanisms in a representative strain. Microbiological Research 04/2014; 169(11).

20.  Hongbin Chen · Xi Yang · Qi Wang · Chunjiang Zhao · Henan Li · Wenqiang He · Xiaojuan Wang · Feifei Zhang · Zhanwei Wang · Minjun Chen · Baoli Zhu · Hui Wang. 2014. Insights on evolution of virulence and resistance from the whole-genome analysis of a predominant methicillin-resistant Staphylococcus aureus clone sequence type 239 in China. Chinese Science Bulletin 04/2014; 59(11):1104-1112.

21.  Mariela Segura · Han Zheng · Astrid de Greeff · George F Gao · Daniel Grenier · Yongqiang Jiang · Chengping Lu · Duncan Maskell · Kazunori Oishi · Masatoshi Okura · [...] · Jiaqi Tang · Tobias Tenenbaum · Prasit Tharavichitkul · Ngo Thi Hoa · Peter Valentin-Weigand · Jerry M Wells · Heiman Wertheim · Baoli Zhu · Jianguo Xu · Marcelo Gottschalk. 2014. Latest developments on Streptococcus suis: An emerging zoonotic pathogen: Part 2. Future Microbiology 05/2014; 9(5):587-91.

22.  Mariela Segura · Han Zheng · Astrid de Greeff · George F Gao · Daniel Grenier · Yongqiang Jiang · Chengping Lu · Duncan Maskell · Kazunori Oishi · Masatoshi Okura · [...] · Jiaqi Tang · Tobias Tenenbaum · Prasit Tharavichitkul · Ngo Thi Hoa · Peter Valentin-Weigand · Jerry M Wells · Heiman Wertheim · Baoli Zhu · Marcelo Gottschalk · Jianguo Xu. 2014. Latest developments on Streptococcus suis: An emerging zoonotic pathogen: Part 1. Future Microbiology 04/2014; 9(4):441-4.

23.  Na Lu · Yongfei Hu · Liying Zhu · Xi Yang · Yeshi Yin · Fang Lei · Yongliang Zhu · Qin Du · Xin Wang · Zhiqi Meng · Baoli Zhu. 2014. DNA microarray analysis reveals that antibiotic resistance-gene diversity in human gut microbiota is age related. Scientific Reports 03/2014; 4:4302.

24.  Yong Yi · Na Lu · Fei Liu · Jing Li · Ruifen Zhang · Liping Jia · Hua Jing · Hu Xia · Yi Yang · Baoli Zhu · Yongfei Hu · Yan Cui. 2014. Genome sequence and comparative analysis of a Vibrio cholerae O139 strain E306 isolated from a cholera case in China. Gut Pathogens 02/2014; 6(1):3.

25.  Yongfei Hu · Xi Yang · Na Lu · Baoli Zhu. 2014. The abundance of antibiotic resistance genes in human guts has correlation to the consumption of antibiotics in animal. Gut Microbes 01/2014; 5(2).

26.  Lunbiao Cui · Di Liu · Weifeng Shi · Jingcao Pan · Xian Qi · Xianbin Li · Xiling Guo · Minghao Zhou · Wei Li · Joel Haywood · [...] · Qinglan Sun · Linhuan Wu · Ruifu Yang · Jinghua Yan · Fumin Lei · Baoli Zhu · Wenjun Liu · Juncai Ma · Hua Wang · George F Gao. 2014. Dynamic reassortments and genetic heterogeneity of the human-infecting influenza A (H7N9) virus. Nature Communications 01/2014; 5:3142.

27.  Xianhui Wang · Xiaodong Fang · Pengcheng Yang · Xuanting Jiang · Feng Jiang · Dejian Zhao · Bolei Li · Feng Cui · Jianing Wei · Chuan Ma · [...] · Qiye Li · Zhiyong Huang · Xiaoming Yao · Na Lv · Guojie Zhang · Yingrui Li · Jian Wang · Jun Wang · Baoli Zhu · Le Kang. 2014. The locust genome provides insight into swarm formation and long-distance flight. Nature Communications 01/2014; 5:2957.

28.  Bin Li · Yongfei Hu · Qi Wang · Yong Yi · Patrick C Y Woo · Hua Jing · Baoli Zhu · Cui Hua Liu. 2013. Structural Diversity of Class 1 Integrons and Their Associated Gene Cassettes in Klebsiella pneumoniae Isolates from a Hospital in China. PLoS ONE 09/2013; 8(9):e75805.

29.  Lucia Gonzales, Zahra Bagher Ali, Erik Nygren, Zhiyun Wang, Stefan Karlsson, Baoli Zhu · Marianne Quiding-Järbrink, Asa Sjöling. 2013. Alkaline pH Is a Signal for Optimal Production and Secretion of the Heat Labile Toxin, LT in Enterotoxigenic Escherichia Coli (ETEC). PLoS ONE 09/2013; 8(9):e74069.

30.  Yuying Zhu · Yong Yi · Xi Yang · Na Lv · Jing Li · Baoli Zhu · Yongfei Hu. 2013. Discovery of new structure of class 1 integron in MDR Pseudomonas aeruginosa and its association with drug-resistance. ACTA MICROBIOLOGICA SINICA 09/2013; 53(9):927-32.

31.  Wen Zhang · Yuanyuan Zhang · Huajun Zheng · Yuanlong Pan · Haican Liu · Pengcheng Du · Li Wan · Jun Liu · Baoli Zhu · Guoping Zhao · Chen Chen · Kanglin Wan. 2013. Genome Sequencing and Analysis of BCG Vaccine Strains. PLoS ONE 08/2013; 8(8):e71243.

32.  Yuanli Mao · Enbo Cui · Chunmei Bao · Zhenhong Liu · Suming Chen · Juling Zhang · Huan Wang · Chenglong Zhang · Jing Zou · John D Klena · Baoli Zhu · Fen Qu · Zhiyun Wang. 2013.  Changing trends and serotype distribution of Shigella species in Beijing from 1994 to 2010. Gut Pathogens 08/2013; 5(1):21. DOI:10.1186/1757-4749-5-21

33.  Yuxuan Qin · Jing Li · Qiuya Wang · Kexin Gao · Baoli Zhu · Na Lv. 2013. Identification of lactic acid bacteria in commercial yogurt and their antibiotic resistance. ACTA MICROBIOLOGICA SINICA 08/2013; 53(8):889-97

34. Hu Y, Yang X, Qin J, Lu N, Cheng G, Wu N, Pan Y, Li J, Zhu L, Wang X, Meng Z, Zhao F, Liu D, Ma J, Qin N, Xiang C, Xiao Y, Li L, Yang H, Wang J, Yang R, Gao GF, Wang J, Zhu B. 2013. Metagenome-wide analysis of antibiotic resistance genes in a large cohort of human gut microbiota. Nat Commun. 2013 Jul 23;4:2151.

35. Wu N, Yang X, Zhang R, Li J, Xiao X, Hu Y, Chen Y, Yang F, Lu N, Wang Z, Luan C, Liu Y, Wang B, Xiang C, Wang Y, Zhao F, Gao GF, Wang S, Li L, Zhang H, Zhu B. 2013. Dysbiosis signature of fecal microbiota in colorectal cancer patients. Microb Ecol. 2013 Aug;66(2):462-70.

36. Chen Y, Zhang H, Xiao X, Jia Y, Wu W, Liu L, Jiang J, Zhu B, Meng X, Chen W. 2013. Peripheral blood transcriptome sequencing reveals rejection- relevant genes in long-term heart transplantation. Int J Cardiol. 2013 Apr 18.

37. Yang X, Liu D, Liu F, Wu J, Zou J, Xiao X, Zhao F, Zhu B. 2013. HTQC: a fast quality control toolkit for Illumina sequencing data. BMC Bioinformatics. 2013 Jan 31;14:33.

38. Li H, Yang Y, Zhang R, Cai Y, Yang X, Wang Z, Li Y, Cheng X, Ye X, Xiang Y, Zhu B. 2013. Preferential sites for the integration and disruption of human papillomavirus 16 in cervical lesions. J Clin Virol. 2013 Apr;56(4):342-7.

39. Li H, Zhang R, Cai Y, Li Y, Cheng X, Zhu B, Yang Y, Xiang Y. 2012. Determination of integrated HPV58 sequences in cervical lesions. Int J Gynecol Cancer. 2012 Sep;22(7):1234-7.

40. Howe K … Zhu B, … de Jong … Stemple DL et al. 2013. The zebrafish reference genome sequence and its relationship to the human genome. Nature. 2013 Apr 25;496(7446):498-503.

41. Smith JJ, Kuraku S, Holt C, Sauka-Spengler T, Jiang N, Campbell MS, Yandell MD, Manousaki T, Meyer A, Bloom OE, Morgan JR, Buxbaum JD, Sachidanandam R, Sims C, Garruss AS, Cook M, Krumlauf R, Wiedemann LM, Sower SA, Decatur WA, Hall JA, Amemiya CT, Saha NR, Buckley KM, Rast JP, Das S, Hirano M, McCurley N, Guo P, Rohner N, Tabin CJ, Piccinelli P, Elgar G, Ruffier M, Aken BL, Searle SM, Muffato M, Pignatelli M, Herrero J, Jones M, Brown CT, Chung-Davidson YW, Nanlohy KG, Libants SV, Yeh CY, McCauley DW, Langeland JA, Pancer Z, Fritzsch B, de Jong PJ, Zhu B, Fulton LL, Theising B, Flicek P, Bronner ME, Warren WC, Clifton SW, Wilson RK, Li W. 2013. Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet. 2013 Apr;45(4):415-21.

42. Scally A, Dutheil JY, Hillier LW, Jordan GE, Goodhead I, Herrero J, Hobolth A, Lappalainen T, Mailund T, Marques-Bonet T, McCarthy S, Montgomery SH, Schwalie PC, Tang YA, Ward MC, Xue Y, Yngvadottir B, Alkan C, Andersen LN, Ayub Q, Ball EV, Beal K, Bradley BJ, Chen Y, Clee CM, Fitzgerald S, Graves TA, Gu Y, Heath P, Heger A, Karakoc E, Kolb-Kokocinski A, Laird GK, Lunter G, Meader S, Mort M, Mullikin JC, Munch K, O'Connor TD, Phillips AD, Prado-Martinez J, Rogers AS, Sajjadian S, Schmidt D, Shaw K, Simpson JT, Stenson PD, Turner DJ, Vigilant L, Vilella AJ, Whitener W, Zhu B, Cooper DN, de Jong P, Dermitzakis ET, Eichler EE, Flicek P, Goldman N, Mundy NI, Ning Z, Odom DT, Ponting CP, Quail MA, Ryder OA, Searle SM, Warren WC, Wilson RK, Schierup MH, Rogers J, Tyler-Smith C, Durbin R. 2012. Insights into hominid evolution from the gorilla genome sequence. Nature. 2012 Mar 7;483(7388):169-75.

43. Cheng G, Hu Y, Yin Y, Yang X, Xiang C, Wang B, Chen Y, Yang F, Lei F, Wu N, Lu N, Li J, Chen Q, Li L, Zhu B. 2012. Functional screening of antibiotic resistance genes from human gut microbiota reveals a novel gene fusion. FEMS Microbiol Lett. 2012 Nov;336(1):11-6.

44. Na Wu, Yuanyuan Zhang, Jun Fu, Ruifen Zhang, Lan Feng, Yongfei Hu, Xiaoliang Li, Na Lu, Xiuqin Zhao, Yuanlong Pan, Jing Li, Baoli Zhu*, and Kanglin Wan*. 2012. Performance Assessment of a novel two-step MDA-PCR (Multiple Displacement Amplification as a pre-polymerase chain reaction) assay for Detection of Mycobacterium tuberculosis Complex from Sputum Specimens. Journal of Clinical Microbiology. (online, doi:10.1128/JCM.05787-11)

45. Nguyen DK, Yang F, Kaul R, Alkan C, Antonellis A, Friery KF, Zhu B, de Jong PJ, Disteche CM. 2012. Clcn4-2 genomic structure differs between the X locus in Mus spretus and the autosomal locus in Mus musculus: AT motif enrichment on the X. Genome Res. 2011 Mar;21(3):402-9.

46. Yongfei Hu, Wei Zhang, Hui Liang, Liping Liu, Guojun Peng, Yuanlong Pan, Xi Yang, Beiwen Zheng, George F. Gao, Baoli Zhu* and Hongyan Hu*. 2011. Whole-Genome Sequence of a Multidrug Resistant Clinical Isolate of Acinetobacter lwoffii. Journal of Bacteriology. 193 (19): 5549-5550

47.  Hongyan Hu^#, Yongfei Hu#, Yuanlong Pan, Hui Liang, Haiyan Wang, Xiumei Wang, Qinfang Hao, Xiaoli Yang, Xi Yang, Xue Xiao, Chunguang Luan, Yi Yang, Yujun Cui, Ruifu Yang, George F. Gao, Yajun Song*, and Baoli Zhu*. 2012. Novel Plasmid and Its Variant Harboring both a bla_NDM-1 Gene and Type IV Secretion System in Clinical Isolates of Acinetobacter lwoffii. Antimicrob Agents Chemother. (online, doi:10.1128/AAC.06199-11)

48.  Jiabo Ding, Yuanlong Pan, Hai Jiang, Junsheng Cheng, Taotao Liu, Nan Qin, Yi Yang, Buyun Cui, Chenchen, Cuihua Liu, Kairong Mao*, Baoli Zhu*. 2011. The whole genome sequences of four Brucella strains. Journal of Bacteriology. 193 (14):3674-3675.

49.  Yanfei Chen, Fengling Yang, Haifeng Lu, Baohong Wang, Yunbo Chen, Dajiang Lei, Yuezhu Wang, Baoli Zhu*, Lanjuan Li*.2011. Characterization of Fecal Microbial Community in Patients with Liver Cirrhosis. HEPATOLOGY. 54(2):562-72

50.  Yuanlong Pan, Xi Yang, Jing Li, Ruifen Zhang, Yongfei Hu, Yuguang Zhou, Jun Wang, and Baoli Zhu*. 2011. The genome sequence of spinosyns-producing bacterium Saccharopolyspora spinosa NRRL 18395. Journal of Bacteriology. 193(12):3150-1 (doi:10.1128/JB.00344-11)