发表论文
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Interference with LTβR signaling by tick saliva facilitates transmission of Lyme disease spirochetes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2022, 119(47): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704693/.[7] TingTing Fu, YanBo Sun, Wei Gao, ChengBo Long, ChunHua Yang, XinWang Yang, Yi Zhang, XinQiang Lan, Song Huang, JieQiong Jin, Robert W Murphy, Yun Zhang, Ren Lai, David M Hillis, YaPing Zhang, Jing Che. The highest-elevation frog provides insights into mechanisms and evolution of defenses against high UV radiation. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2022, 119(46): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9674958/.[8] Meiquan Li, Xiaopeng Tang, Zhiyi Liao, Chuanbin Shen, Ruomei Cheng, Mingqian Fang, Gan Wang, Ya Li, Shuzhen Tang, Li Xie, Zhiye Zhang, Peter Muiruri Kamau, James Mwangi, Qiumin Lu, Yaxiong Li, Yuming Wang, Daniel Thomas MacKeigan, Eric G Cerenzia, Heyu Ni, Ren Lai. Hypoxia and low temperature upregulate transferrin to induce hypercoagulability at high altitude. BLOOD[J]. 2022, 140(19): 2063-2075, http://dx.doi.org/10.1182/blood.2022016410.[9] Chen, Xue, Deng, Suixin, Wang, Wenchao, Castiglione, Stefania, Duan, Zilei, Luo, Lei, Cianci, Francesca, Zhang, Xiaoxue, Xu, Jianglei, Li, Hao, Zhao, Jizong, Kamau, Peter Muiruri, Zhang, Zhiye, Mwangi, James, Li, Jiali, Shu, Yousheng, Hu, Xintian, Mazzanti, Michele, Lai, Ren. Human antimicrobial peptide LL-37 contributes to Alzheimer's disease progression. MOLECULAR PSYCHIATRY[J]. 2022, 27(11): 4790-4799, http://dx.doi.org/10.1038/s41380-022-01790-6.[10] Luo, Lei, Kamau, Peter Muiruri, Lai, Ren. Bioactive Peptides and Proteins from Wasp Venoms. BIOMOLECULES[J]. 2022, 12(4): http://dx.doi.org/10.3390/biom12040527.[11] Mingqian Fang, Xiaopeng Tang, Juan Zhang, Zhiyi Liao, Gan Wang, Ruomei Cheng, Zhiye Zhang, Hongwen Zhao, Jing Wang, Zhaoxia Tan, Peter Muiruri Kamau, Qiumin Lu, Qi Liu, Guohong Deng, Ren Lai. An inhibitor of leukotriene-A 4 hydrolase from bat salivary glands facilitates virus infection. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2022, 119(10): https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8915838/.[12] Gan Wang, Min Zhang, Ping Meng, Chengbo Long, Xiaodong Luo, Xingwei Yang, Yunfei Wang, Zhiye Zhang, James Mwangi, Peter Muiruri Kamau, Zhi Daic, Zunfu Ke, Yi Zhang, Wenlin Chen, Xudong Zhao, Fei Ge, Qiumin Lv, Mingqiang Rong, Dongsheng Li, Yang Jin, Xia Sheng, Ren Lai. Anticarin-β shows a promising antiosteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis. 药学学报:英文版[J]. 2022, 12(5): 2268-2279, http://lib.cqvip.com/Qikan/Article/Detail?id=7107612198.[13] Zhang, Zhiye, Shen, Chuanbin, Fang, Mingqian, Han, Yajun, Long, Chengbo, Liu, Weihui, Yang, Min, Liu, Ming, Zhang, Dengdeng, Cao, Qiqi, Chen, Xue, Fang, Yaqun, Lu, Qiumin, Hou, Zongliu, Li, Yaxiong, Liu, Zhenze, Lei, Xi, Ni, Heyu, Lai, Ren. Novel contact-kinin inhibitor sylvestin targets thromboinflammation and ameliorates ischemic stroke. CELLULAR AND MOLECULAR LIFE SCIENCES[J]. 2022, 79(5): http://dx.doi.org/10.1007/s00018-022-04257-7.[14] Xie, TianZhen, Luo, Lei, Zhao, YunLi, Li, Hao, Xiang, MeiLing, Qin, XuJie, He, YingJie, Zhu, YanYan, Dai, Zhi, Wang, ZhaoJie, Wei, Xin, Liu, YaPing, Zhao, LiXing, Lai, Ren, Luo, XiaoDong. Steroidal Alkaloids with a Potent Analgesic Effect Based on N-type Calcium Channel Inhibition. ORGANIC LETTERS[J]. 2022, 24(2): 467-471, http://dx.doi.org/10.1021/acs.orglett.1c02853.[15] Wang, Yunfei, Yin, Chuanlin, Zhang, Hao, Kamau, Peter Muiruri, Dong, Wenqi, Luo, Anna, Chai, Longhui, Yang, Shilong, Lai, Ren. Venom resistance mechanisms in centipede show tissue specificity. CURRENT BIOLOGY[J]. 2022, 32(16): 3556-+, http://dx.doi.org/10.1016/j.cub.2022.06.074.[16] Hao Zhang, Chengsan Wang, Keyi Zhang, Peter Muiruri Kamau, Anna Luo, Lifeng Tian, Ren Lai. The role of TRPA1 channels in thermosensation. CELL INSIGHT[J]. 2022, 1(6): 100059-, http://dx.doi.org/10.1016/j.cellin.2022.100059.[17] Luo, Anna, Wang, Aili, Kamau, Peter Muiruri, Lai, Ren, Luo, Lei. Centipede Venom: A Potential Source of Ion Channel Modulators. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES[J]. 2022, 23(13): [18] Luo, Han, Wang, Gan, Chen, Nan, Fang, Zemin, Xiao, Yazhong, Zhang, Min, Gerelt, Khishigjargal, Qian, Yingying, Lai, Ren, Zhou, Yu. A Superefficient Ochratoxin A Hydrolase with Promising Potential for Industrial Applications. APPLIED AND ENVIRONMENTAL MICROBIOLOGY[J]. 2022, 88(2): http://dx.doi.org/10.1128/AEM.01964-21.[19] Liao, Zhiyi, Tang, Xiaopeng, Chen, Wenlin, Jiang, Xuelong, Chen, Zhongzheng, He, Kai, Li, Quan, Duan, Zilei, He, Xiaoqin, Kamau, Peter Muiruri, Lv, Longbao, Zhang, Zhiye, Rong, Mingqiang, Lv, Qiumin, Lai, Ren. Shrew's venom quickly causes circulation disorder, analgesia and hypokinesia. 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Role of LL-37 in thrombotic complications in patients with COVID-19. CELLULAR AND MOLECULAR LIFE SCIENCES[J]. 2022, 79(6): http://dx.doi.org/10.1007/s00018-022-04309-y.[23] Shen, Chuanbin, Liu, Ming, Mackeigan, Daniel Thomas, Chen, Zi Yan, Chen, Pingguo, Karakas, Danielle, Li, June, Norris, Peter A A, Li, Jiayao, Deng, Yanling, Long, Chengbo, Lai, Ren, Ni, Heyu. Viper venoms drive the macrophages and hepatocytes to sequester and clear platelets: novel mechanism and therapeutic strategy for venom-induced thrombocytopenia. ARCHIVES OF TOXICOLOGY[J]. 2021, 95(11): 3589-3599, http://dx.doi.org/10.1007/s00204-021-03154-5.[24] Zheng, Fenshuang, Zhang, Min, Yang, Xingwei, Wu, Feilong, Wang, Gan, Feng, Xingxing, Ombati, Rose, Zuo, Ruiling, Yang, Canju, Liu, Jun, Lai, Ren, Luo, Xiaodong, Long, Chengbo. Prostaglandin E1 Is an Efficient Molecular Tool for Forest Leech Blood Sucking. 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A Strategy for Efficient Preparation of Genus-Specific Diagnostic Antibodies for Snakebites. FRONTIERS IN IMMUNOLOGY[J]. 2021, 12: http://dx.doi.org/10.3389/fimmu.2021.775678.[28] Jingjing Wang, Mengyao Ji, Bingqian Yuan, Anna Luo, Zhenyuan Jiang, Tengyu Zhu, Yang Liu, Peter Muiruri Kamau, Lin Jin, Ren Lai. Peptide OPTX-1 From Ornithodoros papillipes Tick Inhibits the pS273R Protease of African Swine Fever Virus. FRONTIERS IN MICROBIOLOGY[J]. 2021, 12: https://doaj.org/article/d98ecd840501467684d49054c1fb4529.[29] Zhu, TengYu, Qiu, Huan, Cao, QiQi, Duan, ZiLei, Liu, FengLiang, Song, TianZhang, Liu, Yang, Fang, YaQun, Wu, GuangMing, Zheng, YongTang, Ding, WenJun, Lai, Ren, Jin, Lin. Particulate matter exposure exacerbates susceptibility to SARS-CoV-2 infection in humanized ACE2 mice. ZOOLOGICAL RESEARCH[J]. 2021, 42(3): 335-+, http://dx.doi.org/10.24272/j.issn.2095-8137.2021.088.[30] Xu KuanHong, Zhou Meng, Wu FeiLong, Tang XiaoPeng, Lu QiuMin, Lai Ren, Long ChengBo. Identification and characterization of a novel elastase inhibitor from Hirudinaria manillensis. CHINESE JOURNAL OF NATURAL MEDICINES[J]. 2021, 19(7): 540-544, http://dx.doi.org/10.1016/S1875-5364(21)60054-7.[31] Han, Yalan, Luo, Anna, Kamau, Peter Muiruri, Takomthong, Pitchayakarn, Hu, Jingmei, Boonyarat, Chantana, Luo, Lei, Lai, Ren. A plant-derived TRPV3 inhibitor suppresses pain and itch. BRITISH JOURNAL OF PHARMACOLOGY[J]. 2021, 178(7): 1669-1683, http://dx.doi.org/10.1111/bph.15390.[32] Min Zhang, Zhi Dai, Xudong Zhao, Gan Wang, Ren Lai. Anticarin β Inhibits Human Glioma Progression by Suppressing Cancer Stemness via STAT3. FRONTIERS IN ONCOLOGY[J]. 2021, 11: https://doaj.org/article/1e1e93ad2bc143f8aae133bc3f8db8c0.[33] Li, Yan, Zhang, Jinyong, Duan, Zilei, Wang, Ning, Sun, Xiangcheng, Zhang, Yanjing, Fu, Li, Liu, Kaiyun, Yang, Yongjun, Pan, Shulei, Shi, Yun, Zeng, Hao, Guo, Gang, Lai, Ren, Zou, Quanming. High-throughput screening and evaluation of repurposed drugs targeting the SARS-CoV-2 main protease. SIGNAL TRANSDUCTION AND TARGETED THERAPYnull. 2021, 6(1): 2978-2980, http://dx.doi.org/10.1038/s41392-021-00763-5.[34] Wang, Gan, Yang, MengLi, Duan, ZiLei, Liu, FengLiang, Jin, Lin, Long, ChengBo, Zhang, Min, Tang, XiaoPeng, Xu, Ling, Li, YingChang, Kamau, Peter Muiruri, Yang, Lian, Liu, HongQi, Xu, JingWen, Chen, JieKai, Zheng, YongTang, Peng, XiaoZhong, Lai, Ren. Dalbavancin binds ACE2 to block its interaction with SARS-CoV-2 spike protein and is effective in inhibiting SARS-CoV-2 infection in animal models. CELL RESEARCH[J]. 2021, 31(1): 17-24, http://dx.doi.org/10.1038/s41422-020-00450-0.[35] Ren Lai. Potentially Contribute to the Prey Immobilization in Protobothrops mucrosquamatus and Trimeresurus stejnegeri Venoms.. Toxins (Basel).. 2020, [36] Zhou, Wenliang, Yang, Shilong, Li, Bowen, Nie, Yonggang, Luo, Anna, Huang, Guangping, Liu, Xuefeng, Lai, Ren, Wei, Fuwen. Why wild giant pandas frequently roll in horse manure. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 117(51): 32493-32498, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768701/.[37] Ren Lai. Transferrin plays a central role in coagulation balance by interacting with clotting factors. Cell Res.. Cell Res. 2020, [38] Tang, Xiaopeng, Fang, Mingqian, Cheng, Ruomei, Zhang, Zhiye, Wang, Yuming, Shen, Chuanbin, Han, Yajun, Lu, Qiumin, Du, Yingrong, Liu, Yingying, Sun, Zhaohui, Zhu, Liping, Mwangi, James, Xue, Min, Long, Chengbo, Lai, Ren. Iron-Deficiency and Estrogen Are Associated With Ischemic Stroke by Up-Regulating Transferrin to Induce Hypercoagulability. CIRCULATIONRESEARCH[J]. 2020, 127(5): 651-663, https://www.webofscience.com/wos/woscc/full-record/WOS:000563917800010.[39] Xing, Meichen, Ji, Mengyao, Hu, Jingmei, Zhu, Tengyu, Chen, Yaoyao, Bai, Xuewei, Mwangi, James, Mo, Guoxiang, Lai, Ren, Jin, Lin. Snake Cathelicidin Derived Peptide Inhibits Zika Virus Infection. FRONTIERS IN MICROBIOLOGY[J]. 2020, 11: https://doaj.org/article/90d3338ba1434eb686fe3d3454606496.[40] Chang, Jiajia, He, Xiaoqin, Hu, Jingmei, Kamau, Peter Muiruri, Lai, Ren, Rao, Dingqi, Luo, Lei. Bv8-Like Toxin from the Frog Venom of Amolops jingdongensis Promotes Wound Healing via the Interleukin-1 Signaling Pathway. TOXINS[J]. 2020, 12(1): http://apps.webofknowledge.com/CitedFullRecord.do?product=UA&colName=WOS&SID=5CCFccWmJJRAuMzNPjj&search_mode=CitedFullRecord&isickref=WOS:000514630000006.[41] Sun, Ruipu, Ying, Ying, Tang, Zhimin, Liu, Ting, Shi, Fuli, Li, Huixia, Guo, Taichen, Huang, Shibo, Lai, Ren. The Emerging Role of the SLCO1B3 Protein in Cancer Resistance. 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Structure-Activity Analysis and Molecular Docking Studies of Coumarins from Toddalia asiatica as Multifunctional Agents for Alzheimer's Disease. BIOMEDICINES[J]. 2020, 8(5): https://www.webofscience.com/wos/woscc/full-record/WOS:000540842200005.[51] Yang, Shilong, Lu, Xiancui, Wang, Yunfei, Xu, Lizhen, Chen, Xiaoying, Yang, Fan, Lai, Ren. A paradigm of thermal adaptation in penguins and elephants by tuning cold activation in TRPM8. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA[J]. 2020, 117(15): 8633-8638, https://www.webofscience.com/wos/woscc/full-record/WOS:000526871700058.[52] James Mwangi, Xue Hao, Ren Lai, ZhiYe Zhang. Antimicrobial peptides:new hope in the war against multidrug resistance. 动物学研究[J]. 2019, 40(6): 488-505, http://lib.cqvip.com/Qikan/Article/Detail?id=7003048991.[53] Fang, Yaqun, He, Xiaoqin, Zhang, Pengcheng, Shen, Chuanbin, Mwangi, James, Xu, Cheng, Mo, Guoxiang, Lai, Ren, Zhang, Zhiye. 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