基本信息
王华林  男  博导  中国科学院武汉病毒研究所
电子邮件: h.wang@wh.iov.cn
通信地址: 湖北省武汉市小洪山中区44号
邮政编码: 430071

招生信息

   
招生专业
071005-微生物学
招生方向
病毒学

工作经历

   
工作简历
2007-09~现在, 中国科学院武汉病毒研究所, 研究员
2002-04~2007-09,中国科学院武汉病毒研究所, 副研究员
2000-07~2002-04,中国科学院武汉病毒研究所, 助理研究员

专利与奖励

   
奖励信息
(1) 国家“万人计划”科技创新领军人才, 国家级, 2017
(2) 科技部2015年创新人才推进计划“中青年科技创新领军人才”, 部委级, 2015
(3) 湖北青年五四奖章, , 省级, 2012
(4) 国家杰出青年科学基金, 部委级, 2012
(5) 湖北省自然科学奖, 一等奖, 省级, 2011
(6) 第二届武汉青年科技奖, , 市地级, 2010
(7) 湖北省自然科学奖, 二等奖, 省级, 2001
(8) 中国科学院院长奖学金, , 院级, 2000
专利成果
( 1 ) 用液相芯片检测呼吸道传染病病原的引物和探针及方法, 2012, 第 1 作者, 专利号: ZL201110067021.1

( 2 ) 用于乙型肝炎病毒共价闭合DNA的检测用品及其应用, 2012, 第 3 作者, 专利号: ZL200810197526.8

( 3 ) 重组杆状病毒AcBac△cc-GP41及其构建方法, 2011, 第 3 作者, 专利号: ZL 2007 1 0052629.0

( 4 ) 高效表达SARS冠状病毒S蛋白的重组杆状病毒及构建。, 2010, 第 2 作者, 专利号: ZL 2007 1 0052485.9

( 5 ) 一种用于检测禽流感病毒H5N1亚型的液相芯片。, 2009, 第 1 作者, 专利号: ZL 2006 1 0018603.X

( 6 ) 一种用于检测乙型肝炎病毒的生物用品。, 2008, 第 1 作者, 专利号: ZL 2006 1 0018346.X

出版信息

   
发表论文
(1) Establishment of a Reverse Genetic System of Severe Fever with Thrombocytopenia Syndrome Virus Based on a C4 Strain, VIROLOGICA SINICA, 2021, 第 4 作者
(2) Immune evasion of SARS-CoV-2 from interferon antiviral system, COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL, 2021, 第 5 作者
(3) Identification, Isolation, and Characterization of an Ectromelia Virus New Strain from an Experimental Mouse, VIROLOGICA SINICA, 2021, 第 9 作者
(4) Immunological detection of serum antibodies in pediatric medical workers exposed to varying levels of SARS-CoV-2, JOURNAL OF INFECTION, 2021, 第 10 作者
(5) Novel SFTSV Phylogeny Reveals New Reassortment Events and Migration Routes, VIROLOGICA SINICA, 2021, 第 14 作者
(6) Systematic analysis of nuclear localization of Autographa californica multiple nucleopolyhedrovirus proteins, JOURNAL OF GENERAL VIROLOGY, 2021, 第 5 作者
(7) SARS-CoV-2 nsp1: Bioinformatics, Potential Structural and Functional Features, and Implications for Drug/Vaccine Designs, FRONTIERS IN MICROBIOLOGY, 2020, 第 5 作者
(8) The Nonstructural Protein of Guertu Virus Disrupts Host Defenses by Blocking Antiviral Interferon Induction and Action, ACS INFECTIOUS DISEASES, 2020, 通讯作者
(9) Combinatorial Minigenome Systems for Emerging Banyangviruses Reveal Viral Reassortment Potential and Importance of a Protruding Nucleotide in Genome "Panhandle" for Promoter Activity and Reassortment, FRONTIERS IN MICROBIOLOGY, 2020, 第 4 作者
(10) Guertu virus NSs protein disrupts host defense by blocking antiviral interferon induction and action, ACS infectious diseases, 2020, 第 7 作者
(11) Host AAA plus ATPase TER94 Plays Critical Roles in Building the Baculovirus Viral Replication Factory and Virion Morphogenesis, JOURNAL OF VIROLOGY, 2020, 通讯作者
(12) Host restriction of emerging high-pathogenic bunyaviruses via MOV10 by targeting viral nucleoprotein and blocking ribonucleoprotein assembly, PLOS PATHOGENS, 2020, 通讯作者
(13) Immunological detection of serum antibodies in pediatric medical workers exposed to varying levels of SARS-CoV-2, Journal of Infection, 2020, 第 10 作者
(14) Per Os Infectivity Factor 5 Identified as a Substrate of P33 in the Baculoviral Disulfide Bond Formation Pathway, JOURNAL OF VIROLOGY, 2020, 第 7 作者
(15) Genomic and transcriptional analyses of novel parvoviruses identified from dead peafowl, VIROLOGY, 2020, 第 9 作者
(16) A RIG-I–like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination, JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 第 3 作者
(17) Interferon-gamma-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1, FRONTIERS IN IMMUNOLOGY, 2019, 通讯作者
(18) Host factor heat-shock protein 90 contributes to baculovirus budded virus morphogenesis via facilitating nuclear actin polymerization, VIROLOGY, 2019, 第 10 作者
(19) Functional Characterization of the Group I Alphabaculovirus Specific Gene ac73, Functional Characterization of the Group I Alphabaculovirus Specific Gene ac73, VIROLOGICA SINICA, 2019, 第 6 作者
(20) Quantitative Proteomic Analysis Reveals Unfolded-Protein Response Involved in Severe Fever with Thrombocytopenia Syndrome Virus Infection, JOURNAL OF VIROLOGY, 2019, 第 8 作者
(21) Baculovirus Per Os Infectivity Factor Complex: Components and Assembly, JOURNAL OF VIROLOGY, 2019, 第 14 作者
(22) First case of laboratory-confirmed severe fever with thrombocytopenia syndrome disease revealed the risk of SFTSV infection in Xinjiang, China, EMERGING MICROBES & INFECTIONS, 2019, 第 10 作者
(23) Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1, JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 第 4 作者
(24) Single-particle tracking reveals the sequential entry process of the bunyavirus severe fever with thrombocytopenia syndrome virus, SMALL, 2019, 第 6 作者
(25) Mito-docking: A Novel In Vivo Method to Detect Protein-Protein Interactions, SMALL METHODS, 2019, 第 4 作者
(26) Heartland virus antagonizes type I and III interferon antiviral signaling by inhibiting phosphorylation and nuclear translocation of STAT2 and STAT1, The Journal of Biological Chemistry, 2019, 第 4 作者
(27) Baculovirus ODV-E66 degrades larval peritrophic membrane to facilitate baculovirus oral infection, VIROLOGY, 2019, 第 8 作者
(28) Genome Analysis of a Novel Clade II.b Alphabaculovirus Obtained from Artaxa digramma, Viruses, 2019, 第 6 作者
(29) Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1, Frontiers in Immunology, 2019, 
(30) The cysteine-rich region of a baculovirus VP91 protein contributes to the morphogenesis of occlusion bodies, VIROLOGY, 2019, 第 8 作者
(31) The Major Hurdle for Effective Baculovirus Transduction into Mammalian Cells Is Passing Early Endosomes, JOURNAL OF VIROLOGY, 2019, 第 7 作者
(32) Taxonomy of the order Bunyavirales : update 2019, ARCHIVES OF VIROLOGY, 2019, 
(33) Improving Baculovirus Transduction of Mammalian Cells by Incorporation of Thogotovirus Glycoproteins, VIROLOGICA SINICA, 2019, 通讯作者
(34) The group i alphabaculovirus-specific protein, ac5, is a novel component of the occlusion body but is not associated with odvs or the pif complex, JOURNAL OF GENERAL VIROLOGY, 2018, 第 6 作者
(35) The first laboratory-confirmed sfts case from the xinjiang uygur autonomous region importing to hainan international tourism island, ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2018, 第 9 作者
(36) Zika Virus Baculovirus-Expressed Virus-Like Particles Induce Neutralizing Antibodies in Mice, VIROLOGICA SINICA, 2018, 通讯作者
(37) HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1, 2, and 3 from MabrNPV: Infectivity and Complex Stability, VIROLOGICA SINICA, 2018, 第 8 作者
(38) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, 中国病毒学:英文版, 2018, 第11作者
(39) Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, VIROLOGICA SINICA, 2018, 通讯作者
(40) Establishment of baculovirus-expressed vlps induced syncytial formation assay for flavivirus antiviral screening, VIRUSES-BASEL, 2018, 通讯作者
(41) The Functional Oligomeric State of Tegument Protein GP41 Is Essential for Baculovirus Budded Virion and Occlusion-Derived Virion Assembly, JOURNAL OF VIROLOGY, 2018, 通讯作者
(42) HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, HearNPV Pseudotyped with PIF1,2,and 3 from MabrNPV:Infectivity and Complex Stability, 中国病毒学:英文版, 2018, 第 8 作者
(43) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group I of Alphabaculovirus, VIROLOGICA SINICA, 2018, 第11作者
(44) A novel tick-borne phlebovirus, closely related to severe fever with thrombocytopenia syndrome virus and Heartland virus, is a potential pathogen, EMERGING MICROBES & INFECTIONS, 2018, 第 20 作者
(45) Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group Ⅰ of Alphabaculovirus, Genome Characteristics of the Cyclophragma Undans Nucleopolyhedrovirus: A Distinct Species in Group Ⅰ of Alphabaculovirus, 中国病毒学:英文版, 2018, 第11作者
(46) 布尼亚病毒目新分类概述, A review and novel classification of Bunyavirales, 生物多样性, 2018, 第 5 作者
(47) Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, Development of Multi-analyte Suspension Assay for Simultaneously Efficient Detection of Avian Influenza Virus A Subtypes, 中国病毒学:英文版, 2018, 第 6 作者
(48) Establishment of Baculovirus-Expressed VLPs Induced Syncytial Formation Assay for Flavivirus Antiviral Screening, Viruses, 2018, 
(49) Genome analysis of a novel Group I alphabaculovirus obtained from Oxyplax ochracea, PLOS ONE, 2018, 第 9 作者
(50) Migration, recombination, and reassortment are involved in the evolution of severe fever with thrombocytopenia syndrome bunyavirus., Infect Genet Evol., 2017, 第 1 作者
(51) The roles of ebolavirus glycoproteins in viral pathogenesis, VIROLOGICA SINICA, 2017, 通讯作者
(52) Construction and rescue of a functional synthetic baculovirus, ACS SYNTHETIC BIOLOGY, 2017, 第 13 作者
(53) 口服感染因子:杆状病毒编码的一种复杂而进化保守的入侵机器, 中国科学. 生命科学, 2017, 第 5 作者
(54) Deltabaculoviruses encode a functional type i budded virus envelope fusion protein, JOURNAL OF GENERAL VIROLOGY, 2017, 第 3 作者
(55) Migration, recombination, and reassortment are involved in the evolution of severe fever with thrombocytopenia syndrome bunyavirus, INFECTION GENETICS AND EVOLUTION, 2017, 第 7 作者
(56) Ebola virus mucin-like glycoprotein (Emuc) induces remarkable acute inflammation and tissue injury: evidence for Emuc pathogenicity in vivo., Protein Cell., 2017, 通讯作者
(57) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction, JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 通讯作者
(58) The roles of ebolavirus glycoproteins in viral pathogenesis., Virol Sin., 2017, 通讯作者
(59) Three Conserved Regions in Baculovirus Sulfhydryl Oxidase P33 Are Critical for Enzymatic Activity and Function, JOURNAL OF VIROLOGY, 2017, 第 6 作者
(60) Per os infectivity factors: a complicated and evolutionarily conserved entry machinery of baculovirus, SCIENCE CHINA-LIFE SCIENCES, 2017, 第 5 作者
(61) A novel glycoprotein D-specific monoclonal antibody neutralizes herpes simplex virus, ANTIVIRAL RESEARCH, 2017, 通讯作者
(62) Phylogenetic analysis revealed the central roles of two African countries in the evolution and worldwide spread of Zika virus, VIROLOGICA SINICA, 2016, 第 5 作者
(63) Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation, JOURNAL OF VIROLOGY, 2016, 通讯作者
(64) Pathologic Studies of Fatal Encephalomyelitis in Children Caused by Enterovirus 71, AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2016, 第 9 作者
(65) 乙型脑炎病毒样颗粒疫苗的制备及其免疫保护效率的初步评价, Generation of Japanese Encephalitis Virus-likeParticle Vaccine and Preliminary Evaluation of Its Protective Efficiency, 病毒学报, 2016, 第 7 作者
(66) The Host Specificities of Baculovirus per os Infectivity Factors, PLOS ONE, 2016, 第 7 作者
(67) P33 of helicoverpa armigera single nucleocapsid nucleopolyhedrovirus is a functional homolog of acp33, VIROLOGICA SINICA, 2016, 第 6 作者
(68) Characterization of two monoclonal antibodies, 38f10 and 44d11, against the major envelope fusion protein of helicoverpa armigera nucleopolyhedrovirus, VIROLOGICA SINICA, 2016, 第 5 作者
(69) Mutational and functional analysis of N-linked glycosylation of envelope fusion protein F of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2016, 通讯作者
(70) Virus like particle-based vaccines against emerging infectious disease viruses, VIROLOGICA SINICA, 2016, 第 5 作者
(71) Characterization of the viral fibroblast growth factor homolog of Helicoverpa armigera single nucleopolyhedrovirus, VIROLOGICA SINICA, 2016, 第 5 作者
(72) Genome Sequencing and Analysis of Catopsilia pomona nucleopolyhedrovirus: A Distinct Species in Group I Alphabaculovirus, PLOS ONE, 2016, 第 8 作者
(73) Glycoprotein E of the Japanese encephalitis virus forms virus-like particles and induces syncytia when expressed by a baculovirus, JOURNAL OF GENERAL VIROLOGY, 2015, 通讯作者
(74) Disruption of Type I Interferon Signaling by the Nonstructural Protein of Severe Fever with Thrombocytopenia Syndrome Virus via the Hijacking of STAT2 and STAT1 into Inclusion Bodies, JOURNAL OF VIROLOGY, 2015, 通讯作者
(75) Crystal Structure of the Core Region of Hantavirus Nucleocapsid Protein Reveals the Mechanism for Ribonucleoprotein Complex Formation., J Virol, 2015, 通讯作者
(76) The FP25K Acts as a Negative Factor for the Infectivity of AcMNPV Budded Virus, PLOS ONE, 2015, 通讯作者
(77) Resistant mutations and quasispecies complexity of hepatitis B virus during telbivudine treatment, JOURNAL OF GENERAL VIROLOGY, 2015, 第11作者
(78) Identification of the epitopes of monoclonal antibodies against P74 of Helicoverpa armigera nucleopolyhedrovirus (vol 28, pg 360, 2013), VIROLOGICA SINICA, 2015, 第 6 作者
(79) An in vitro recombination-based reverse genetic system for rapid mutagenesis of structural genes of the Japanese encephalitis virus, VIROLOGICA SINICA, 2015, 第 4 作者
(80) The FP25K Acts as a Negative Factor for the Infectivity of AcMNPV Budded Virus, PLOS ONE, 2015, 通讯作者
(81) The Complete Genome of a New Betabaculovirus from Clostera anastomosis, PLOS ONE, 2015, 第 9 作者
(82) Genome Sequence and Analysis of Buzura suppressaria Nucleopolyhedrovirus: A Group II Alphabaculovirus, PLOS ONE, 2014, 第 8 作者
(83) Identification and functional analysis of inter-subunit disulfide bonds of the F protein of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2014, 通讯作者
(84) Viral suppression of innate immunity via spatial isolation of TBK1/IKK epsilon from mitochondrial antiviral platform, JOURNAL OF MOLECULAR CELL BIOLOGY, 2014, 通讯作者
(85) 基于液相芯片技术的呼吸道病原体多重检测技术的建立, 医学检验与临床, 2014, 第 3 作者
(86) The ha72 Core Gene of Baculovirus Is Essential for Budded Virus Production and Occlusion-Derived Virus Embedding, and Amino Acid K22 Plays an Important Role in Its Function, JOURNAL OF VIROLOGY, 2014, 第 6 作者
(87) Genomic Sequencing and Analysis of Sucra jujuba Nucleopolyhedrovirus, PLOS ONE, 2014, 第 8 作者
(88) Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antivirai platform, Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antivirai platform, 分子细胞生物学报:英文版, 2014, 第 10 作者
(89) Unraveling the Entry Mechanism of Baculoviruses and Its Evolutionary Implications, JOURNAL OF VIROLOGY, 2014, 通讯作者
(90) Viral suppression of innate immunity via spatial isolation of TBK1/IKKε from mitochondrial antiviral platform, Journal of Molecular Cell Biology, 2014, 第 10 作者
(91) Comparative Proteomics Reveal Fundamental Structural and Functional Differences between the Two Progeny Phenotypes of a Baculovirus, JOURNAL OF VIROLOGY, 2013, 
(92) The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation, PROTEIN & CELL, 2013, 第 10 作者
(93) Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus, Identification of the Epitopes of Monoclonal Antibodies against P74 of Helicoverpa armigera Nucleopolyhedrovirus, 中国病毒学:英文版, 2013, 第 6 作者
(94) Comparative Proteomics Reveal Fundamental Structural and Functional Differences between the Two Progeny Phenotypes of a Baculovirus, JOURNAL OF VIROLOGY, 2013, 第 10 作者
(95) Betabaculovirus F proteins showed different efficiencies when rescuing the infectivity of gp64-null Autographa californica nucleopolyhedrovirus, VIROLOGY, 2013, 通讯作者
(96) Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2012, 第 6 作者
(97) Betabaculovirus F Proteins Showed Different Efficiency when Rescuing the, 2012, 通讯作者
(98) Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro, JOURNAL OF GENERAL VIROLOGY, 2012, 通讯作者
(99) Functional studies of per os infectivity factor 3 of Helicoverpa armigera nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2012, 第 6 作者
(100) Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro.2012., 2012, 通讯作者
(101) Crimean-Congo hemorrhagic fever virus nucleoprotein reveals endonuclease activity in bunyaviruses, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2012, 第 9 作者
(102) Incorporation of GP64 into Helicoverpa armigera nucleopolyhedrovirus enhances virus infectivity in vivo and in vitro, JOURNAL OF GENERAL VIROLOGY, 2012, 通讯作者
(103) ORF85 of HearNPV encodes the per os infectivity factor 4 (PIF4) and is essential for the formation of the PIF complex, VIROLOGY, 2012, 第 4 作者
(104) Genetic Modification of Baculovirus Expression Vectors, Genetic Modification of Baculovirus Expression Vectors, 中国病毒学:英文版, 2012, 第 2 作者
(105) ORF85 of HearNPV encodes the per os infectivity factor 4 (PIF4) and is essential for the formation of the PIF complex.2012., 2012, 第 1 作者
(106) Developments of Subunit and VLP Vaccines Against Influenza A Virus, Developments of Subunit and VLP Vaccines Against Influenza A Virus, 中国病毒学:英文版, 2012, 第 3 作者
(107) Helicoverpa armigera nucleopolyhedrovirus occlusion-derived virus-associated protein, ha100, affects oral infectivity in vivo but not virus replication in vitro, JOURNAL OF GENERAL VIROLOGY, 2011, 第 6 作者
(108) Production and characterization of monoclonal antibodies against the hemagglutinin of h5n1 and antigenic investigation of avian influenza h5n1 viruses isolated from china, CANADIAN JOURNAL OF MICROBIOLOGY, 2011, 第 6 作者
(109) Production of CCHF virus-like particle by a baculovirus-insect cell expression system, Virologica Sinica, 2011, 第 6 作者
(110) Specificity of baculovirus P6.9 basic DNA binding proteins and the critical role of the C-terminus in virion assembly., Journal of Virology, 2010, 第 1 作者
(111) Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions ▿, JOURNAL OF VIROLOGY, 2010, 第 6 作者
(112) Partial Functional Rescue of HearNPV Infectivity by Substitution of F Protein with GP64 from AcMNPV., Journal of Virology, 2010, 通讯作者
(113) AcMNPV efficiently infects Sf9 cells and transduces mammalian cells via direct fusion with the plasma membrane at low pH., Journal of Virology, 2010, 通讯作者
(114) Partial Functional Rescue of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus Infectivity by Replacement of F Protein with GP64 from Autographa californica Multicapsid Nucleopolyhedrovirus ▿, JOURNAL OF VIROLOGY, 2010, 通讯作者
(115) Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, Serial Expression of the Truncated Fragments of the Nucleocapsid Protein of CCHFV and Identification of the Epitope Region, Virologica Sinica, 2010, 第 4 作者
(116) Autographa californica Multicapsid Nucleopolyhedrovirus Efficiently Infects Sf9 Cells and Transduces Mammalian Cells via Direct Fusion with the Plasma Membrane at Low pH ▿, JOURNAL OF VIROLOGY, 2010, 通讯作者
(117) Proteomics of the Autographa californica Nucleopolyhedrovirus Budded Virions ▿, JOURNAL OF VIROLOGY, 2010, 第 6 作者
(118) Specificity of Baculovirus P6.9 Basic DNA-Binding Proteins and Critical Role of the C Terminus in Virion Formation ▿ †, JOURNAL OF VIROLOGY, 2010, 第 4 作者
(119) Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, Evaluation of Sensitivities and Specificities of SARS-CoV Detection by Real-time Quantitative Reverse Transcription-PCR Assays, 中国病毒学:英文版, 2009, 第 3 作者
(120) Angiotensin-converting enzyme 2 (ace2) from raccoon dog can serve as an efficient receptor for the spike protein of severe acute respiratory syndrome coronavirus, JOURNAL OF GENERAL VIROLOGY, 2009, 第 7 作者
(121) Variants of open reading frame bm126 in wild-type bombyx mori nucleopolyhedrovirus isolates exhibit functional differences, JOURNAL OF GENERAL VIROLOGY, 2009, 第 6 作者
(122) Virion Proteomics of Large DNA Viruses, Virion Proteomics of Large DNA Viruses, 中国病毒学:英文版, 2009, 第 3 作者
(123) Evidence of a major role of GP64 in group I alphabaculovirus evolution, VIRUS RESEARCH, 2009, 第 4 作者
(124) An Improved Culture System for Virus Isolation and Detection, An Improved Culture System for Virus Isolation and Detection, 中国病毒学:英文版, 2008, 第 5 作者
(125) Open reading frame bm21 of bombyx mori nucleopolyhedrovirus is not essential for virus replication in vitro, but its deletion extends the median survival time of infected larvae, JOURNAL OF GENERAL VIROLOGY, 2008, 第 5 作者
(126) The F-Like Protein Ac23 Enhances the Infectivity of the Budded Virus of gp64 -Null Autographa californica Multinucleocapsid Nucleopolyhedrovirus Pseudotyped with Baculovirus Envelope Fusion Protein F ▿ †, JOURNAL OF VIROLOGY, 2008, 通讯作者
(127) Green tea extract and its major component epigallocatechin gallate inhibits hepatitis B virus in vitro, ANTIVIRAL RESEARCH, 2008, 通讯作者
(128) An extensive analysis on the global codon usage pattern of baculoviruses, ARCHIVES OF VIROLOGY, 2008, 第 3 作者
(129) The f protein of helicoverpa armigera single nucleopolyhedrovirus can be substituted functionally with its homologue from spodoptera exigua multiple nucleopolyhedrovirus, JOURNAL OF GENERAL VIROLOGY, 2008, 通讯作者
(130) A Functional F Analogue of Autographa californica Nucleopolyhedrovirus GP64 from the Agrotis segetum Granulovirus ▿, JOURNAL OF VIROLOGY, 2008, 通讯作者
(131) 一步法RT—PCR检测人狂犬病毒初探, Primary application of one.step RT-PCR in detection of human rabies, 中国法医学杂志, 2008, 第 2 作者
(132) Mutagenesis and nuclear magnetic resonance analyses of the fusion peptide of Helicoverpa armigera single nucleocapsid nucleopolyhedrovirus F protein, JOURNAL OF VIROLOGY, 2008, 通讯作者
(133) Expression of a ribosome-inactivating protein gene in bitter melon is induced by sphaerotheca fuliginea and abiotic stimuli (vol 29, pg 1605, 2007), BIOTECHNOLOGY LETTERS, 2008, 第 2 作者
(134) HearNPV在生长对数期与平台期宿主细胞中的复制差异分析, Comparative Study of the Replication Difference of HearNPV in Infect Exponential and Stationary Host Cells, 病毒学报, 2007, 第 3 作者
(135) Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, Construction of the Bac-to-Bac System of Bombyx mori Nucleopolyhedroviru, 中国病毒学, 2007, 第 5 作者
(136) The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions, VIROLOGY, 2007, 第 4 作者
(137) Deletion of a helicoverpa armigera nucleopolyhedrovirus gene encoding a virion structural protein (orf 107) increases the budded virion titre and reduces in vivo infectivity, JOURNAL OF GENERAL VIROLOGY, 2007, 第 10 作者
(138) The heptad repeats region is essential for AcMNPV P10 filament formation and not the proline-rich or the C-terminus basic regions, VIROLOGY, 2007, 第 4 作者
(139) 适合棉铃虫细胞HzAm1生长的培养基筛选及低血清驯化, Screen of Media for Insect Cells(HzAm1) Growth and Its Adaptation to Low Serum Culture, 生物工程学报, 2006, 第 2 作者
(140) 缺失p10基因的重组棉铃虫病毒导致多角体囊膜包装不完整, Deletion of p10 From the Genome of HaSNPV Results in a Faulty Polyhedral Envelope, 中国病毒学, 2006, 第 5 作者
(141) HaSNPV的9个基因的转录谱分析, The Transcription Profiles of Nine HaSNPV Genes, 中国病毒学, 2006, 第 3 作者
(142) 流行性感冒病毒的检测及分型方法, 国际检验医学杂志, 2006, 第 3 作者
(143) SARS病毒N蛋白、E蛋白在大肠杆菌中的表达与鉴定, Expression and Purification of Nucleocaspid and Envelope Proteins of SARS Coronavirus, 中国病毒学, 2005, 第 4 作者
(144) 液相芯片MASA技术用于儿童呼吸道感染病原学研究, Etiological Study of Respiratory Tract Infections in Children by Using Multi-analyte Suspension Array Technology, 中国病毒学, 2005, 第 8 作者
(145) 表达GP64的重组HaSNPV的构建研究, Construction of a Recombinant HaSNPV Expressing GP64, 中国病毒学, 2005, 第 2 作者
(146) 棉铃虫单核衣壳核多角体病毒几丁质酶基因的克隆与表达, Molecular Cloning and Expression of the Chitinase Gene from Helicoverpa, 中国病毒学, 2002, 第 2 作者
(147) 棉铃虫核多角体病毒p10基因的序列及转录分析, 病毒学报, 2001, 第 3 作者
(148) 棉铃虫核多角体病毒p6.9,chitinase和p10基因的研究及重组病毒的构建, 2000, 第 1 作者
(149) 油桐尺蠖单粒包埋核型多角体病毒(BusuNPV)BamHI—H片段的序列分析, 中国病毒学, 1999, 第 8 作者
(150) Heartland virus NSs protein disrupts host defenses by blocking the TBK1 kinase–IRF3 transcription factor interaction and signaling required for interferon induction, The Journal of Biological Chemistry, 

科研活动

   
科研项目
( 1 ) Ⅱ型包膜病毒的入侵机制, 负责人, 国家任务, 2010-01--2014-12
( 2 ) 新发和突发传染病病原快速诊断和高通量检测技术平台建设, 负责人, 国家任务, 2009-01--2010-12
( 3 ) 杆状病毒和昆虫细胞间的相互作用, 参与, 国家任务, 2008-01--2012-12
( 4 ) 昆虫病毒感染关键步骤的分子机理研究, 参与, 国家任务, 2009-01--2013-12
( 5 ) 棉铃虫病毒结构蛋白组成和相互作用关系以及调控BV/ODV形成的分子机制的研究, 参与, 国家任务, 2006-12--2010-12
( 6 ) 以沙坦类药物为探针研究血管紧张素Ⅱ受体AT1分子间相互作用机制, 参与, 国家任务, 2009-01--2011-12
( 7 ) 杆状病毒膜融合蛋白介导病毒入侵的分子机制研究, 负责人, 国家任务, 2012-01--2015-12
( 8 ) 我国重要自然宿主及媒介昆虫的病毒病原调查, 负责人, 国家任务, 2013-05--2018-04
( 9 ) 病毒与宿主相互作用的分子机理, 参与, 国家任务, 2014-01--2016-12
( 10 ) 湖北省重大人才工程高端人才引领培养计划:病毒感染及入侵机制的研究, 负责人, 地方任务, 2013-01--2017-12
( 11 ) 快速检测技术和产品研发, 负责人, 中国科学院计划, 2016-01--2018-12
( 12 ) 杆状病毒口服感染的分子机制研究, 负责人, 研究所自选, 2016-07--2018-12
( 13 ) 病毒与宿主相互作用的分子机理, 参与, 国家任务, 2017-01--2019-12
( 14 ) 第三批国家“万人计划”科技创新领军人才, 负责人, 国家任务, 2018-01--2020-12
( 15 ) 生物安全关键技术研发, 负责人, 国家任务, 2018-08--2021-06
参与会议
(1)Mutagenesis and functional analysis of N-linked glycosylations of the major envelope fusion protein of Helicoverpa armigera Single Nucleocapsid Nucleopolyhedrovirus   第44届无脊椎动物病理学年会   王华林   2011-08-07
(2)无   第29届美国病毒学会年会   无   2010-07-17