基本信息
刘宣勇  男  博导  中国科学院上海硅酸盐研究所
电子邮件: xyliu@mail.sic.ac.cn
通信地址: 上海市定西路1295号
邮政编码: 200050

研究领域

主要研究方向:

(1)    生物材料表/界面特性及其生物学效应

(2)    骨植入材料表面改性

(3)    创面修复材料

(4)    抗菌材料

(5)    抗肿瘤材料

(6)    纳米诊疗材料


招生信息

   
招生专业
080502-材料学
080501-材料物理与化学
085204-材料工程
招生方向
生物医用材料表面改性
生物材料表面纳米化及其性能表征
生物材料表面和界面基本科学问题研究

教育背景

   
学历
-- 研究生
学位
-- 博士

专利与奖励

   
专利成果
[1] 曹辉亮, 罗启明, 刘宣勇, 马小涵. 一种用于植入体表面的抗菌涂层及其制备方法. CN: CN113117145A, 2021-07-16.

[2] 曹辉亮, 罗启明, 刘宣勇, 马小涵. 一种用于植入体表面的铁离子改性氧化锌抗菌涂层及其制备方法. CN: CN112853328A, 2021-05-28.

[3] 刘宣勇, 刘丽丹, 彭峰. 一种镁合金表面制备还原氧化石墨烯涂层的方法. CN: CN112391664A, 2021-02-23.

[4] 刘宣勇, 邢顺, 马小涵, 王东辉. 一种表面改性的医用金属材料及其制备方法和应用. CN: CN111778494A, 2020-10-16.

[5] 刘宣勇. 牙种植体系统. CN: CN110292448A, 2019-10-01.

[6] 刘宣勇, 李倩雯, 王东辉. 具有促成骨效应的钛及其合金及其制备方法和应用. CN: CN110218991A, 2019-09-10.

[7] 刘宣勇, 郑立, 马小涵. 一种氮掺杂钛氧化物涂层及其制备方法和应用. CN: CN110180020A, 2019-08-30.

[8] 刘宣勇, 郑立, 马小涵. 一种还原态钛氧化物涂层及制备方法和应用. CN: CN110180034A, 2019-08-30.

[9] 刘宣勇, 张冬冬. 一种在镁及其合金表面原位制备层状双氢氧化物抗腐蚀性涂层的方法. CN: CN110093647A, 2019-08-06.

[10] 乔玉琴, 刘宣勇. 兼具骨修复功能和抗菌性能的医用钛基复合涂层及其制备方法. CN: CN107304472B, 2019-06-11.

[11] 刘宣勇, 王东辉. 一种具有载药层状双氢氧化物薄膜的医用钛基材料及其制备方法和应用. CN: CN106344964B, 2019-05-14.

[12] 刘宣勇, 彭峰. 一种超疏水镁或镁合金材料及其制备方法和应用. CN: CN107190255B, 2019-04-16.

[13] 刘宣勇, 彭峰. 具有良好抗腐蚀性与生物相容性的表面改性镁合金材料及其制备方法和应用. CN: CN106567062B, 2019-03-19.

[14] 曹辉亮, 唐楷为, 刘宣勇. 一种金属元素掺杂二硫化钼薄膜材料及其制备方法. CN: CN109467126A, 2019-03-15.

[15] 曹辉亮, 唐楷为, 刘宣勇. 一种铁掺杂二硫化钼涂层材料及其制备方法和应用. CN: CN109467958A, 2019-03-15.

[16] 刘宣勇, 金国栋. 对钛金属材料进行表面改性的方法及改性的钛金属材料. 中国: CN104726836B, 2018.01.09.

[17] 刘宣勇, 孙振杰, 欧阳丽萍, 马小涵. 一种对PEEK表面改性的方法. CN: CN108503877A, 2018-09-07.

[18] 刘宣勇, 彭峰. 一种仿贻贝表面改性镁合金及其制备方法和应用. CN: CN108273125A, 2018-07-13.

[19] 刘宣勇, 王东辉. 一种表面改性生物医用镍钛合金及其制备方法和应用. 中国: CN105343941B, 2018-06-22.

[20] 刘宣勇, 王东辉. 一种镍钛合金载药材料及其制备方法. 中国: CN105536077B, 2018-05-08.

[21] 刘宣勇, 李剑. 一种锆离子注入改善医用聚醚醚酮材料生物活性的方法. 中国: CN105331946B, 2018-04-03.

[22] 刘宣勇, 邱家军. 一种医用金属材料的表面改性方法. CN: CN107841778A, 2018-03-27.

[23] 刘宣勇, 彭峰. 一种表面载药镁合金材料及其制备方法和应用. CN: CN107537071A, 2018-01-05.

[24] 刘宣勇, 彭锋. 一种表面改性镁合金材料及其制备方法和应用. 中国: CN106702238A, 2017-05-24.

[25] 刘宣勇. 牙种植体系统. 中国: CN106037962A, 2016.10.26.

[26] 刘宣勇, 陆涛, 孟凡浩. 对聚醚醚酮材料进行表面改性的方法及改性的聚醚醚酮材料. 中国: CN105132869A, 2015.12.09.

[27] 刘宣勇, 陆涛. 一种对聚醚醚酮材料进行表面改性的方法. 中国: CN104975267A, 2015.10.14.

[28] 刘宣勇, 欧阳丽萍. 一种对聚醚醚酮表面进行改性的方法. 中国: CN104497344A, 2015.04.08.

[29] 刘宣勇, 金国栋. 等离子体浸没离子注入技术对种植牙钉进行表面改性的方法. 中国: CN104911558A, 2015-09-16.

[30] 刘宣勇, 王东辉. 具有选择性抑癌作用的表面改性镍钛合金材料及其制备方法和应用. 中国: CN104436315A, 2015-03-25.

[31] 刘宣勇, 王贺莹, 孟凡浩. 一种表面氟化的聚醚醚酮材料及其制备方法. 中国: CN104371134A, 2015-02-25.

[32] 郭向欣, 刘宣勇, 黄诗婷, 孟凡浩. 一种改性锂空气电池空气电极的制备方法及其应用. 中国: CN104064837A, 2014-09-24.

[33] 刘宣勇, 余乐. 一种医用钛表面复合涂层及其制备方法. 中国: CN104001207A, 2014-08-27.

[34] 刘宣勇, 王贺莹. 一种聚醚醚酮材料及其表面改性的方法. 中国: CN103881129A, 2014-06-25.

[35] 刘宣勇, 王贺莹. 一种聚醚醚酮材料及其表面改性的方法. 中国: CN103865084A, 2014-06-18.

[36] 曹辉亮, 钱仕, 刘宣勇. 一种制备低氧氧化钛纳米管阵列的方法. 中国: CN103866370A, 2014-06-18.

[37] 刘宣勇, 田雅馨. 一种氧化钛复合涂层及其制备方法. 中国: CN103834945A, 2014-06-04.

[38] 刘宣勇, 钱仕. 制备钛种植体的方法及得到的钛种植体. 中国: CN103736148A, 2014-04-23.

[39] 刘宣勇, 陆涛. 注入钽离子对聚醚醚酮表面进行改性的方法及改性的聚醚醚酮材料. 中国: CN103614699A, 2014-03-05.

[40] 刘宣勇, 钱仕. 一种牙科种植体及其制备方法. 中国: CN103536371A, 2014-01-29.

[41] 刘宣勇, 钱仕. 医用钛表面载金纳米管薄膜的制备方法. 中国: CN103451705A, 2013-12-18.

[42] 刘宣勇, 陆涛. 注入钛离子对聚醚醚酮表面进行改性的方法. 中国: CN103242551A, 2013-08-14.

[43] 刘宣勇, 陆涛. 注入钙离子对聚醚醚酮表面进行改性的方法. 中国: CN103225067A, 2013-07-31.

[44] 刘宣勇, 钱仕, 丁传贤. 一种用于钛金属工件阳极氧化的通用性夹具装置. 中国: CN202881422U, 2013-04-17.

[45] 曹辉亮, 刘宣勇. 一种兼具成骨及抗菌性能的钛表面改性方法. 中国: CN103014646A, 2013-04-03.

[46] 刘宣勇, 李晋波. 一种改善医用钛金属的抗菌性和生物活性的表面改性方法. 中国: CN102330051A, 2012.01.25.

[47] 刘宣勇, 钱仕. 一种基于钛金属表面的纳米复合材料及其制备方法. 中国: CN102677055A, 2012-09-19.

[48] 曹辉亮, 刘宣勇. 一种抗菌涂层及其制备方法. 中国: CN102580149A, 2012-07-18.

[49] 胡红杰, 刘宣勇, 丁传贤. 一种锌掺杂多孔纳米氧化钛涂层及其制备方法. 中国: CN102371005A, 2012-03-14.

[50] 刘宣勇, 李晋波. 一种医用钛金属材料的表面改性方法. 中国: CN102191454A, 2011.09.21.

[51] 刘宣勇, 李子卉, 孟凡浩. 一种对钛金属表面进行改性的方法. 中国: CN102181842A, 2011.09.14.

[52] 胡红杰, 刘宣勇, 丁传贤. 一种硅掺杂多孔纳米氧化钛涂层及其制备方法. 中国: CN102049064A, 2011-05-11.

[53] 胡红杰, 刘宣勇, 丁传贤. 一种镁掺杂多孔纳米氧化钛涂层的制备方法及其应用. 中国: CN101928974A, 2010.12.29.

[54] 胡红杰, 刘宣勇, 丁传贤. 一种在钛及其合金表面制备氟化钙涂层的方法和应用. 中国: CN101914799A, 2010-12-15.

[55] 李宝娥, 刘宣勇, 丁传贤. 一种抗菌型硅灰石复合涂层及制备方法. 中国: CN101549174, 2009-10-07.

[56] 李宝娥, 刘宣勇, 丁传贤. 一种抗菌型氧化钛复合涂层及制备方法. CN: CN101417146A, 2009-04-29.

[57] 王国成, 刘宣勇, 丁传贤. 一种低温下稳定的纯单斜氧化锆涂层、制备方法及应用. 中国: CN101219239, 2008-07-16.

[58] 刘宣勇, 赵晓兵, 丁传贤. 一种氢离子注入提高纳米氧化钛涂层生物活性的方法. CN: CN1739810A, 2006-03-01.

[59] 刘宣勇, 赵晓兵, 丁传贤. 一种制备具有生物活性的纳米氧化钛涂层的方法. CN: CN1651604A, 2005-08-10.

[60] 谢有桃, 刘宣勇, 郑学斌, 丁传贤. 硅酸二钙/氧化锆复合承载骨替换材料及制备方法. CN: CN1613513A, 2005-05-11.

[61] 刘宣勇, 郑学斌, 陶顺衍, 丁传贤. 硅酸二钙涂层-钛合金承载骨替换材料及制备方法. CN: CN1380112A, 2002-11-20.

[62] 刘宣勇, 郑学斌, 丁传贤. 硅灰石涂层-钛合金承载骨替换材料及制备方法. 中国: CN1351890, 2002-06-05.

出版信息

   
发表论文
[1] Chen, Lan, Wang, Donghui, Liu, Xingdan, Yan, Bangcheng, Zhang, Haifeng, Zhang, Xianming, Qiao, Yuqin, Qiu, Jiajun, Liu, Xuanyong. Micro-galvanic effects of silver-containing titanium implants regulate the immune responses via activating voltage-gated calcium channels in macrophages. CHEMICAL ENGINEERING JOURNAL[J]. 2022, 428: http://dx.doi.org/10.1016/j.cej.2021.131068.
[2] Shen, Jie, Chen, Bo, Zhai, Xinyun, Qiao, Wei, Wu, Shuilin, Liu, Xuanyong, Zhao, Ying, Ruan, Changshun, Pan, Haobo, Chu, Paul K, Cheung, Kenneth M C, Yeung, Kelvin W K. Stepwise 3D-spatio-temporal magnesium cationic niche: Nanocomposite scaffold mediated microenvironment for modulating intramembranous ossification. BIOACTIVE MATERIALS[J]. 2021, 6(2): 503-519, https://doaj.org/article/a4e8e24891574ed59d4597ef28869d65.
[3] Zhang, Haifeng, Qiu, Jiajun, Yan, Bangcheng, Liu, Lidan, Chen, Dafu, Liu, Xuanyong. Regulation of Ce (III)/Ce (IV) ratio of cerium oxide for antibacterial application. ISCIENCE[J]. 2021, 24(3): http://dx.doi.org/10.1016/j.isci.2021.102226.
[4] Yin, Shi, Zhang, Wenjie, Tang, Yanmei, Yang, Guangzheng, Wu, Xiaolin, Lin, Sihan, Liu, Xuanyong, Cao, Huiliang, Jiang, Xinquan. Preservation of alveolar ridge height through mechanical memory: A novel dental implant design. BIOACTIVE MATERIALS[J]. 2021, 6(1): 75-83, http://lib.cqvip.com/Qikan/Article/Detail?id=7103722955.
[5] Zhang, Haifeng, Qiu, Jiajun, Liu, Xuanyong. Enhanced antioxidant capability and osteogenic property of medical titanium by cerium plasma immersion ion implantation. SURFACES AND INTERFACES[J]. 2021, 26: http://dx.doi.org/10.1016/j.surfin.2021.101402.
[6] Qin, Hui, Cao, Huiliang, Zhao, Yaochao, Zhu, Cheng, Cheng, Tao, Wang, Qiaojie, Peng, Xiaochun, Cheng, Mengqi, Wang, Jiaxin, Jin, Guodong, Jiang, Yao, Zhang, Xianlong, Liu, Xuanyong, Chu, Paul K. In vitro and in vivo anti-biofilm effects of silver nanoparticles immobilized on titanium (vol 35, pg 9114, 2014). BIOMATERIALSnull. 2021, 269: 0-0, https://www.webofscience.com/wos/woscc/full-record/WOS:000617965200004.
[7] Liu, Yang, Zhai, Shaojie, Jiang, Xingwu, Liu, Yanyan, Wang, Kun, Wang, Chaochao, Zhang, Meng, Liu, Xuanyong, Bu, Wenbo. Intracellular Mutual Promotion of Redox Homeostasis Regulation and Iron Metabolism Disruption for Enduring Chemodynamic Therapy. ADVANCED FUNCTIONAL MATERIALS[J]. 2021, 31(17): http://dx.doi.org/10.1002/adfm.202010390.
[8] Lin, Zhengjie, Shen, Danni, Zhou, Weixiao, Zheng, Yufeng, Kong, Tiantian, Liu, Xuanyong, Wu, Shuilin, Chu, Paul K, Zhao, Ying, Wu, Jun, Cheung, Kenneth M C, Yeung, Kelvin W K. Regulation of extracellular bioactive cations in bone tissue microenvironment induces favorable osteoimmune conditions to accelerate in situ bone regeneration. BIOACTIVE MATERIALS[J]. 2021, 6(8): 2315-2330, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7840811/.
[9] Li, Baoe, Zhang, Lei, Wang, Donghui, Liu, Xuanyong, Li, Haipeng, Liang, Chunyong, Zhao, Xiaoyan. Thermo-sensitive hydrogel on anodized titanium surface to regulate immune response. SURFACE & COATINGS TECHNOLOGY[J]. 2021, 405: http://dx.doi.org/10.1016/j.surfcoat.2020.126624.
[10] Wang, Lanyu, Luo, Qiming, Zhang, Xianming, Qiu, Jiajun, Qian, Shi, Liu, Xuanyong. Co-implantation of magnesium and zinc ions into titanium regulates the behaviors of human gingival fibroblasts. BIOACTIVE MATERIALS[J]. 2021, 6(1): 64-74, http://lib.cqvip.com/Qikan/Article/Detail?id=7103722954.
[11] Sun, Yingxiao, Liu, Xingdan, Tan, Ji, Lv, Dan, Song, Wengang, Su, Rui, Li, Ling, Liu, Xuanyong, Ouyang, Liping, Liao, Yun. Strontium ranelate incorporated 3D porous sulfonated PEEK simulating MC3T3-E1 cell differentiation. REGENERATIVE BIOMATERIALS[J]. 2021, 8(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000637327900004.
[12] Wang, Xiao, Guo, Jingshu, Wen, Jin, Zhang, Xiangkai, Cao, Lingyan, Zeng, Deliang, Liu, Xuanyong, Jiang, Xinquan. Novel vascular strategies on polyetheretherketone modification in promoting osseointegration in ovariectomized rats. MATERIALS & DESIGN[J]. 2021, 202: http://dx.doi.org/10.1016/j.matdes.2021.109526.
[13] Feng Peng, Yulin Lin, Dongdong Zhang, Qingdong Ruan, Kaiwei Tang, Mei Li, Xuanyong Liu, Paul K Chu, Yu Zhang. Corrosion Behavior and Biocompatibility of Diamond-like Carbon-Coated Zinc: An In Vitro Study. ACS OMEGA[J]. 2021, 6(14): 9843-9851, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8047653/.
[14] Hui Qin, Huiliang Cao, Yaochao Zhao, Cheng Zhu, Tao Cheng, Qiaojie Wang, Xiaochun Peng, Mengqi Cheng, Jiaxin Wang, Guodong Jin, Yao Jiang, Xianlong Zhang, Xuanyong Liu, Paul K Chu. Corrigendum to "In vitro and in vivo anti-biofilm effects of silver nanoparticles immobilized on titanium" Biomaterials (2014) 9114–9125. Biomaterials. 2021, 269: http://dx.doi.org/10.1016/j.biomaterials.2020.120615.
[15] Liu, Shifeng, Wang, Qingge, Liu, Wei, Tang, Yujin, Liu, Jia, Zhang, Haifeng, Liu, Xuanyong, Liu, Jingxian, Yang, Junlin, Zhang, LaiChang, Wang, Yan, Xu, Jing, Lu, Weijie, Wang, Liqiang. Multi-scale hybrid modified coatings on titanium implants for non-cytotoxicity and antibacterial properties. NANOSCALE[J]. 2021, 13(23): 10587-10599, http://dx.doi.org/10.1039/d1nr02459k.
[16] Cheng, Shi, Zhang, Dongdong, Li, Mei, Liu, Xuanyong, Zhang, Yu, Qian, Shi, Peng, Feng. Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg. BIOACTIVE MATERIALS[J]. 2021, 6(1): 91-105, http://lib.cqvip.com/Qikan/Article/Detail?id=7103722957.
[17] Wang, Jie, Peng, Feng, Wu, Xiaolin, Wang, Donghui, Zheng, Ao, Cao, Lingyan, Yu, Chunhua, Liu, Xuanyong, Jiang, Xinquan. Biocompatibility and bone regeneration of PEO/Mg-Al LDH-coated pure Mg: an in vitro and in vivo study. SCIENCE CHINA-MATERIALS[J]. 2021, 64(2): 460-473, https://www.webofscience.com/wos/woscc/full-record/WOS:000559952500002.
[18] Chen, Lan, Wang, Donghui, Qiu, Jiajun, Zhang, Xianming, Liu, Xingdan, Qiao, Yuqin, Liu, Xuanyong. Synergistic effects of immunoregulation and osteoinduction of ds-block elements on titanium surface. BIOACTIVE MATERIALS[J]. 2021, 6(1): 191-207, http://lib.cqvip.com/Qikan/Article/Detail?id=7103722965.
[19] Zhang, Dongdong, Peng, Feng, Liu, Xuanyong. Protection of magnesium alloys: From physical barrier coating to smart self-healing coating. JOURNAL OF ALLOYS AND COMPOUNDSnull. 2021, 853: http://dx.doi.org/10.1016/j.jallcom.2020.157010.
[20] Tian, Peng, Peng, Feng, Wang, Donghui, Liu, Xuanyong. Corrosion behavior and cytocompatibility of fluoride-incorporated plasma electrolytic oxidation coating on biodegradable AZ31 alloy (vol 4, pg 1, 2017). REGENERATIVE BIOMATERIALSnull. 2020, 7(3): 337-338, https://www.webofscience.com/wos/woscc/full-record/WOS:000577171600011.
[21] Yu, Le, Tian, Yaxin, Qiao, Yuqin, Liu, Xuanyong. Mn-containing titanium surface with favorable osteogenic and antimicrobial functions synthesized by PIII&D (vol 152, pg 376, 2017). COLLOIDS AND SURFACES B-BIOINTERFACESnull. 2020, 191: [22] Xie, Xiaoxue, Peng, Zhenqi, Wang, Ziqi, Hua, Xinyi, Wang, Zhifang, Deng, Keqin, Yang, Xiumei, Huang, Haowen, Liu, Xuanyong. Monitoring biothiols dynamics in living cells by ratiometric fluorescent gold carbon dots. TALANTA[J]. 2020, 218: http://dx.doi.org/10.1016/j.talanta.2020.121214.
[23] Cheng, Shi, Wang, Wanshun, Wang, Donghui, Li, Binglin, Zhou, Jielong, Zhang, Dongdong, Liu, Lidan, Peng, Feng, Liu, Xuanyong, Zhang, Yu. Anin vitroandin vivocomparison of Mg(OH)(2)-, MgF2- and HA-coated Mg in degradation and osteointegration. BIOMATERIALS SCIENCE[J]. 2020, 8(12): 3320-3333, https://www.webofscience.com/wos/woscc/full-record/WOS:000542957800005.
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[228] Huang, Haowen, Qu, Caiting, Liu, Xuanyong, Huang, Shaowen, Xu, Zhongjian, Liao, Bo, Zeng, Yonglong, Chu, Paul K. Preparation of Controllable Core-Shell Gold Nanoparticles and Its Application in Detection of Silver Ions. ACS APPLIED MATERIALS & INTERFACES[J]. 2011, 3(2): 183-190, https://www.webofscience.com/wos/woscc/full-record/WOS:000287639400015.
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[231] Liu, Xiangmei, Wu, Shuilin, Yeung, Kelvin W K, Chan, Y L, Hu, Tao, Xu, Zushun, Liu, Xuanyong, Chung, Jonathan C Y, Cheung, Kenneth M C, Chu, Paul K. Relationship between osseointegration and superelastic biomechanics in porous NiTi scaffolds. BIOMATERIALS[J]. 2011, 32(2): 330-338, http://dx.doi.org/10.1016/j.biomaterials.2010.08.102.
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[234] Ma, Zhao, Chen, Feng, Zhu, YingJie, Cui, Ting, Liu, XuanYong. Amorphous calcium phosphate/poly(D,L-lactic acid) composite nanofibers: Electrospinning preparation and biomineralization. JOURNAL OF COLLOID AND INTERFACE SCIENCE[J]. 2011, 359(2): 371-379, http://dx.doi.org/10.1016/j.jcis.2011.04.023.
[235] Xuanyong Liu. Wettability controlling by DLC coated nanowire topography. Nanotechnology. 2011, [236] 潘张翼, 曹聪, 刘宣勇, 董宇启. 载银硅灰石涂层抗菌性能实验研究. 国际骨科学杂志. 2011, 32(3): 185-188, http://lib.cqvip.com/Qikan/Article/Detail?id=37954656.
[237] Guocheng Wang, Zufu Lu, 刘宣勇, Xiaming Zhou, 丁传贤, Hala Zreiqat. Nanostructured glass-ceramic coatings for orthopaedic applictions. Journal of the Royal Society Interface[J]. 2011, 8(61): http://www.irgrid.ac.cn/handle/1471x/634852.
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[246] 胡红杰, 刘宣勇, 丁传贤. 等离子体电解氧化制备生物活性多孔纳米TiOB2B 涂层. 无机材料学报[J]. 2011, 26(6): 585-590, http://www.irgrid.ac.cn/handle/1471x/634854.
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指导学生

已指导学生

王国成  博士研究生  080502-材料学  

现指导学生

李子卉  硕士研究生  080502-材料学  

胡红杰  博士研究生  080502-材料学  

田雅馨  硕士研究生  080502-材料学  

金国栋  硕士研究生  080502-材料学