基本信息
刘元红  女  博导  中国科学院上海有机化学研究所
电子邮件: yhliu@sioc.ac.cn
通信地址: 上海市零陵路345号
邮政编码: 200032

招生信息

   
招生专业
070303-有机化学
招生方向
过渡金属金,镍及铜催化的反应及有机硼化合物的合成

教育背景

1997-04--2000-03   北海道大学   博士
1992-09--1995-07   郑州大学   硕士
1988-09--1992-07   郑州大学   学士

工作经历

   
工作简历
2003-10~现在, 中科院上海有机所, 研究员,****获得者
2000-04~2003-09,北海道大学催化研究中心, JSPS,COE研究员,博士后研究员
1997-04~2000-03,北海道大学, 博士
1992-09~1995-07,郑州大学, 硕士
1988-09~1992-07,郑州大学, 学士
社会兼职
2022-12-01-2027-02-28,河南省科学院, 河南省精细化工重点实验室主任
2019-07-01-今,郑州大学, 教授

教授课程

物理有机化学

专利与奖励

   
奖励信息
(1) Thieme化学杂志奖, , 其他, 2007
(2) 日本化学会杰出报告奖, , 其他, 2007
专利成果
( 1 ) 烷基腈类化合物的制备方法, 2023, 第 1 作者, 专利号: CN111484472B

( 2 ) 一种卤化物氢解的方法, 2020, 第 1 作者, 专利号: CN112142544A

( 3 ) 烷基腈类化合物的制备方法, 2020, 第 1 作者, 专利号: CN111484472A

( 4 ) 一种烷基腈类化合物的制备方法, 2020, 第 1 作者, 专利号: CN111099942A

( 5 ) 一种烷基腈类化合物的制备方法, 2020, 第 1 作者, 专利号: CN111099941A

( 6 ) 一种烯基氰类化合物的制备方法, 2019, 第 1 作者, 专利号: CN110272357A

( 7 ) 一种芳香腈或烯基腈类化合物的制备方法, 2019, 第 1 作者, 专利号: CN110117237A

( 8 ) 一种芳香腈或杂芳香腈类化合物的制备方法, 2018, 第 1 作者, 专利号: CN108623495A

( 9 ) 并四苯及并五苯类化合物的合成方法, 2014, 第 1 作者, 专利号: CN103664499A

( 10 ) 3-位取代中氮茚类化合物和高效合成方法, 2009, 第 1 作者, 专利号: CN100528873C

( 11 ) 多环芳烃类化合物、合成方法及其用途, 2008, 第 1 作者, 专利号: CN101125794A

出版信息

   
发表论文
(1) Copper-catalyzed silylation of propargyl carbonates: a general entry to allenylsilanes, ORGANIC CHEMISTRY FRONTIERS, 2023, 第 4 作者  通讯作者
(2) Photoredox/Nickel Dual-Catalyzed Regioselective Allylic Arylations of Allyl Trifluoroborates with Aryl Halides, ORGANIC LETTERS, 2023, 第 5 作者  通讯作者
(3) 4,5-Dihydro-1,2,4-oxadiazole as a Single Nitrogen Transfer Reagent: Synthesis of Functionalized Isoxazoles Assisted by Sc(OTf)(3) or Au(I)/Sc(OTf)(3) Synergistic Catalysis, ORGANIC LETTERS, 2023, 第 3 作者  通讯作者
(4) Nickel-Catalyzed Direct Substitution of Allylic Alcohols with Nitriles: A General Tool for the Construction of Acyclic C2-Tertiary or Quaternary Benzyl Nitriles, ORGANIC LETTERS, 2023, 第 3 作者  通讯作者
(5) Gold(III) or Gold(I)/Lewis-Acid-Catalyzed Substitution/Cyclization/1,2-Migration Reactions of Propargyl Alcohols with 3-Amino-benzodisoxazoles: Synthesis of Pyrimidine Derivatives, ORGANIC LETTERS, 2022, 第 4 作者  通讯作者
(6) Gold(III) or Gold(I)/Lewis-Acid-Catalyzed Substitution/Cyclization/1,2-Migration Reactions of Propargyl Alcohols with 3-Amino-benzodisoxazoles: Synthesis of Pyrimidine Derivatives br, ORGANIC LETTERS, 2022, 第 4 作者  通讯作者
(7) Copper-catalyzed ortho-alkenylation of quinolone N-oxides with alkynes., Org. Chem. Front., 2022, 第 3 作者  通讯作者
(8) Gold(III) or Gold(I)/Lewis-Acid-Catalyzed Substitution/Cyclization/1,2-Migration Reactions of Propargyl Alcohols with 3-Amino-benzo[d]isoxazoles: Synthesis of Pyrimidine Derivatives., Org. Lett., 2022, 第 4 作者  通讯作者
(9) Ligand-Controlled Regiodivergent Cyanoboration of Internal Allenes by Copper Catalysis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 6 作者  通讯作者
(10) Gold-Catalyzed Cyclization of Ynones Involving cis-Hydrofunctionalizations: Rapid Assembly of C-, O-, or S-Functionalized Pyrroles by a Single Methodology, ORGANIC LETTERS, 2022, 第 5 作者  通讯作者
(11) Gold-Catalyzed Cyclization of Ynones Involving cis-Hydrofunctionalizations: Rapid Assembly of C-, O-, or S-Functionalized Pyrroles by a Single Methodology., Org. Lett., 2022, 第 4 作者  通讯作者
(12) Nickel-Catalyzed beta-Regioselective Amination/Cyclization of Ynamide-Nitriles with Amines: Synthesis of Functionalized 3-Aminoindoles and 4-Aminoisoquinolines, ORGANIC LETTERS, 2021, 第 5 作者  通讯作者
(13) Gold-Catalyzed Oxidative Cyclization Involving Nucleophilic Attack to the Keto Group of alpha,alpha '-Dioxo Gold Carbene and 1,2-Alkynyl Migration: Synthesis of Furan-3-carboxylates, ORGANIC LETTERS, 2021, 第 3 作者  通讯作者
(14) Gold-Catalyzed Spirocyclization of Furan-ynones and Unexpected Skeleton Rearrangement of the Resulting Spirohydrofurans, ORGANIC LETTERS, 2021, 第 7 作者  通讯作者
(15) Synthesis of ortho-Diamino-Functionalized 1-Arylnaphthalenes through Nickel-Catalyzed Cyclization of Ynamide-Benzylnitriles with Organoboronic Acids, ORGANIC LETTERS, 2021, 第 4 作者  通讯作者
(16) Nickel-Catalyzed C(sp3)���H Functionalization of Benzyl Nitriles: Direct Michael Addition to Terminal Vinyl Ketones, Org. Lett., 2021, 第 5 作者  通讯作者
(17) Nickel-Catalyzed C(sp(3))-H Functionalization of Benzyl Nitriles: Direct Michael Addition to Terminal Vinyl Ketones, ORGANIC LETTERS, 2021, 第 5 作者  通讯作者
(18) Gold-Catalyzed Oxidative Cyclization Involving Nucleophilic Attack to the Keto Group of ��,�����-Dioxo Gold Carbene and 1,2-Alkynyl Migration: Synthesis of Furan-3-carboxylates, Org. Lett., 2021, 第 3 作者  通讯作者
(19) Cascade Skeletal Rearrangement of Gold Carbene Intermediates: Synthesis of Medium-Sized Pyrimidine-Fused Benzolactones, ADVANCED SYNTHESIS & CATALYSIS, 2021, 第 4 作者  通讯作者
(20) Nickel-Catalyzed Cross-Coupling of Aryl Pivalates with Cyclobutanols Involving C-O and C-C Bond Cleavage, Nickel-Catalyzed Cross-Coupling of Aryl Pivalates with Cyclobutanols Involving C-O and C-C Bond Cleavage, CHINESE JOURNAL OF CHEMISTRY, 2020, 第 4 作者  通讯作者
(21) Gold/Lewis acid catalyzed oxidative cyclization involving activation of nitriles, CHEMICAL COMMUNICATIONS, 2020, 第 4 作者  通讯作者
(22) Synthesis of phospholes and 1,1 '-biphospholes mediated by zirconacyclopentadienes and PBr3, TETRAHEDRON LETTERS, 2020, 第 5 作者  通讯作者
(23) Nickel-Catalyzed Homo- and Cross-Coupling of Allyl Alcohols via Allyl Boronates, ORGANIC LETTERS, 2020, 
(24) Nickel-Catalyzed Cyanation of Unactivated Alkyl Sulfonates with Zn(CN)(2), ORGANIC LETTERS, 2020, 第 4 作者  通讯作者
(25) Copper-Catalyzedortho-Functionalization of QuinolineN-Oxides with Vinyl Arenes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2020, 第 3 作者  通讯作者
(26) Ligand-Controlled Regiodivergent Silylation of Allylic Alcohols by Ni/Cu Catalysis for the Synthesis of Functionalized Allylsilanes, ORGANIC LETTERS, 2019, 第 3 作者  通讯作者
(27) Ligandless nickel-catalyzed transfer hydrogenation of alkenes and alkynes using water as the hydrogen donor, ORGANIC CHEMISTRY FRONTIERS, 2019, 第 7 作者  通讯作者
(28) Benzofurazan N Oxides as Mild Reagents for the Generation of �� Imino Gold Carbenes: Synthesis of Functionalized 7 Nitroindoles., Org. Lett., 2019, 第 1 作者  通讯作者
(29) Benzofurazan N-Oxides as Mild Reagents for the Generation of alpha-Imino Gold Carbenes: Synthesis of Functionalized 7-Nitroindoles, ORGANIC LETTERS, 2019, 第 4 作者  通讯作者
(30) Nickel-catalyzed highly regioselective hydrocyanation of alkenes with Zn(CN)(2), ORGANIC CHEMISTRY FRONTIERS, 2019, 第 4 作者  通讯作者
(31) Dehalogenative Deuteration of Unactivated Alkyl Halides Using D2O as the Deuterium Source, JOURNAL OF ORGANIC CHEMISTRY, 2019, 第 5 作者  通讯作者
(32) 金催化的扩环反应: 2,3-苯并二氮杂(艹卓)类化合物的高效合成, Gold-Catalyzed Ring Expansion Reaction: Highly Efficient Synthesis of Functionalized 2,3-Benzodiazepine Scaffolds, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 5 作者  通讯作者
(33) Nickel-Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents, CHINESE JOURNAL OF CHEMISTRY, 2018, 第 3 作者  通讯作者
(34) 23. 金催化的扩环反应: 2,3-苯并二氮杂䓬类化合物的高效合成, 有机化学, 2018, 第 1 作者  通讯作者
(35) Nickel-Catalyzed Highly Regioselective Hydrocyanation of Terminal Alkynes with Zn(CN)(2) Using Water as the Hydrogen Source, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2018, 第 3 作者  通讯作者
(36) Nickel-Catalyzed Cyanation of Phenol Derivatives with Zn(CN)(2) Involving C-O Bond Cleavage, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 4 作者  通讯作者
(37) 22. Nickel-Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents., Chin. J. Chem., 2018, 第 1 作者  通讯作者
(38) Copper-Catalyzed Borylative Cyclization of o-(Cyano)phenyl Propargyl Carbonates: Synthesis of Functionalized 1-Naphthylamines, ORGANIC LETTERS, 2018, 第 4 作者  通讯作者
(39) Selective 5+1 and 5+2 Cycloaddition of Ynamides or Propargyl Esters with Benzodisoxazoles via Gold Catalysis, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 4 作者  通讯作者
(40) 17. Gold(I)-Catalyzed Formal Intramolecular Dehydro-Diels���Alder Reaction of Ynamide-ynes: Synthesis of Functionalized Benzo[b]carbazoles., Org. Lett., 2018, 第 1 作者  通讯作者
(41) Nickel-Catalyzed Cyanation of Unactivated Alkyl Chlorides or Bromides with Zn(CN)(2), ORGANIC LETTERS, 2018, 第 6 作者  通讯作者
(42) Gold-Catalyzed Oxidative Cyclizations of {o-(Alkynyl)phenyl propargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration: Synthesis of Functionalized 1H-lsochromenes and 2H-Pyrans, ORGANIC LETTERS, 2018, 第 6 作者  通讯作者
(43) 金催化的扩环反应: 2,3-苯并二氮杂(艹卓)类化合物的高效合成, Gold-Catalyzed Ring Expansion Reaction: Highly Efficient Synthesis of Functionalized 2,3-Benzodiazepine Scaffolds, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 5 作者  通讯作者
(44) Gold-Catalyzed Oxidative Cyclizations of {o���(Alkynyl)phenylpropargyl} Silyl Ether Derivatives Involving 1,2-Enynyl Migration:Synthesis of Functionalized 1H���Isochromenes and 2H���Pyrans, Org. Lett., 2018, 第 1 作者  通讯作者
(45) Gold(I)-Catalyzed Formal Intramolecular Dehydro-Diels-Alder Reaction of Ynamide-ynes: Synthesis of Functionalized Benzobcarbazoles, ORGANIC LETTERS, 2018, 第 4 作者  通讯作者
(46) Nickel-Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents, Nickel-Catalyzed Direct Coupling of Allylic Alcohols with Organoboron Reagents, 中国化学:英文版, 2018, 第 3 作者
(47) Ligand-Effect in Gold(I)-Catalyzed Rautenstrauch Rearrangement: Regio- and Stereoselective Synthesis of Bicyclo3.2.1octa-3,6-dienes through Cyclodimerization of 1-Ethynyl-2-propenyl Esters, JOURNAL OF ORGANIC CHEMISTRY, 2018, 第 5 作者  通讯作者
(48) Gold-Catalyzed Cadiot-Chodkiewicz-type Cross-Coupling of Terminal Alkynes with Alkynyl Hypervalent Iodine Reagents: Highly Selective Synthesis of Unsymmetrical 1,3-Diynes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 第 4 作者  通讯作者
(49) General and Mild Nickel-Catalyzed Cyanation of Aryl/Heteroaryl Chlorides with Zn(CN)(2): Key Roles of DMAP, ORGANIC LETTERS, 2017, 第 4 作者  通讯作者
(50) Base-Catalyzed Cyclization of 1,6-Diynyl Carboxylates Involving Propargyl-Allenyl Isomerization: Efficient Synthesis of Benzobfluorene and Its Analogues, ADVANCED SYNTHESIS & CATALYSIS, 2017, 第 5 作者  通讯作者
(51) Gold-Catalyzed Formal 3+2 Cycloaddition of Ynamides with 4,5-Dihydro-1,2,4-oxadiazoles: Synthesis of Functionalized 4-Aminoimidazoles, ORGANIC LETTERS, 2017, 第 4 作者  通讯作者
(52) Copper-Catalyzed Borylative Cyclization of in Situ Generated o-Allenylaryl Nitriles with Bis(pinacolato)diboron, ORGANICLETTERS, 2017, 第 3 作者  通讯作者
(53) Synthesis of functionalized indolizines via gold(I)-catalyzed intramolecular hydroarylation/aromatization of pyrrole-ynes, ORGANIC & BIOMOLECULAR CHEMISTRY, 2017, 第 4 作者  通讯作者
(54) Synthesis of delta- and alpha-Carbolines via Nickel-Catalyzed 2+2+2 Cycloaddition of Functionalized Alkyne-Nitriles with Alkynes, ORGANIC LETTERS, 2017, 第 4 作者  通讯作者
(55) PBr3-Mediated Cyclization of 1,7-Diyn-3,6-bis(propargyl carbonate)s: Synthesis of 5-Bromotetracenes, JOURNAL OF ORGANIC CHEMISTRY, 2017, 第 7 作者  通讯作者
(56) Gold-Catalyzed Cyclization of Furan-Ynes bearing a Propargyl Carbonate Group: Intramolecular Diels-Alder Reaction with In Situ Generated Allenes, CHEMISTRY-A EUROPEAN JOURNAL, 2016, 第 4 作者  通讯作者
(57) Nickel-catalyzed cyclization of alkyne-nitriles with organoboronic acids involving anti-carbometalation of alkynes, CHEMICAL SCIENCE, 2016, 第 3 作者  通讯作者
(58) Gold(I)-Catalyzed Cascade Hydroarylation/Cycloaromatization to Indolizines via Pyridine Ring Construction, JOURNAL OF ORGANIC CHEMISTRY, 2016, 第 3 作者  通讯作者
(59) Dioxazoles, a new mild nitrene transfer reagent in gold catalysis: highly efficient synthesis of functionalized oxazoles, CHEMICAL COMMUNICATIONS, 2016, 第 4 作者  通讯作者
(60) Nickel-Catalyzed 2+2+2 Cycloaddition of Alkyne-Nitriles with Alkynes Assisted by Lewis Acids: Efficient Synthesis of Fused Pyridines, CHEMISTRY-A EUROPEAN JOURNAL, 2016, 第 7 作者  通讯作者
(61) Gold-catalyzed cyclization of 1,6-diynyl dithioacetals via 1,7-carbene transfer and aromatic c-h functionalization, CHEMICAL COMMUNICATIONS, 2016, 第 4 作者  通讯作者
(62) Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines, CHEMICAL COMMUNICATIONS, 2015, 第 10 作者  通讯作者
(63) 1. Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridines or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds, Angew. Chem. Int. Ed., 2015, 第 1 作者  通讯作者
(64) Gold-Catalyzed Oxidative Ring Expansion of 2-Alkynyl-1,2-Dihydropyridines or -quinolines: Highly Efficient Synthesis of Functionalized Azepine or Benzazepine Scaffolds, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 第 5 作者  通讯作者
(65) Gold(I)-Catalyzed 1,2-Acyloxy Migration/3+2 Cycloaddition of 1,6-Diynes with an Ynamide Propargyl Ester Moiety: Highly Efficient Synthesis of Functionalized Cyclopentabindoles, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 4 作者  通讯作者
(66) 6. Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade., Chem. Commun., 2015, 第 1 作者  通讯作者
(67) 2. Cyano-Schmittel Cyclization through Base-Induced Propargyl-Allenyl Isomerization: Highly Modular Synthesis of Pyridine-Fused Aromatic Derivatives., Chem. Eur. J., 2015, 第 1 作者  通讯作者
(68) 3. Gold(I)-Catalyzed 1,2-Acyloxy Migration/[3+2] Cycloaddition of 1,6-Diynes with an Ynamide Propargyl Ester Moiety: Highly Efficient Synthesis of Functionalized Cyclopenta[b]indoles, Chem. Eur. J., 2015, 第 1 作者  通讯作者
(69) 5. Cp2TiCl2-catalyzed cis-hydroalumination of propargylic amines with Red-Al: stereoselective synthesis of Z-configured allylic amines, Chem. Commun, 2015, 第 1 作者  通讯作者
(70) 7. Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade, Org. Lett., 2015, 第 1 作者  通讯作者
(71) Gold-Catalyzed Ring Expansion of Alkynyl Heterocycles through 1,2-Migration of an Endocyclic Carbon-Heteroatom Bond, CHEMISTRYAEUROPEANJOURNAL, 2015, 第 6 作者  通讯作者
(72) 4. Gold(I)-Catalyzed 1,4- and/or 1,5-Heteroaryl Migration Reactions through Regiocontrolled Cyclizations, Chem. Eur. J., 2015, 第 1 作者  通讯作者
(73) Synthesis of Multiple-Substituted Pyrroles via Gold(I)-Catalyzed Hydroamination/Cyclization Cascade, ORGANIC LETTERS, 2015, 第 6 作者
(74) 2. Zirconium-Mediated Multicomponent Reactions of 1,3-Butadiynes with Ylidenemalononitriles to Form Functionalized 1,8-Naphthyridine and Cyclopenta[b]pyridine Derivatives, Chem. Eur. J., 2015, 第 1 作者  通讯作者
(75) 4. Reactions of Zirconocene���1-Aza-1,3-diene Complexes with Acyl Cyanides: Substrate-Dependent Synthesis of Acyl- or Non-Acyl-Substituted Pyrroles., Organometallics, 2015, 第 1 作者  通讯作者
(76) Cyano-Schmittel Cyclization through Base-Induced Propargyl-Allenyl Isomerization: Highly Modular Synthesis of Pyridine-Fused Aromatic Derivatives, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 5 作者
(77) Palladium-catalyzed highly efficient synthesis of functionalized indolizines via cross-coupling/cycloisomerization cascade, CHEMICAL COMMUNICATIONS, 2015, 第 3 作者  通讯作者
(78) Reactions of Zirconocene-1-Aza-1,3-diene Complexes with Acyl Cyanides: Substrate-Dependent Synthesis of Acyl- or Non-Acyl-Substituted Pyrroles, ORGANOMETALLICS, 2015, 第 5 作者  通讯作者
(79) Gold-Catalyzed Synthesis of Tropone and Its Analogues via Oxidative Ring Expansion of Alkynyl Quinols, ORGANIC LETTERS, 2015, 第 5 作者
(80) 1. Gold-Catalyzed Synthesis of Tropone and Its Analogues via Oxidative Ring Expansion of Alkynyl Quinols., Org. Lett., 2015, 第 1 作者  通讯作者
(81) Zirconium-Mediated Multicomponent Reactions of 1,3-Butadiynes with Ylidenemalononitriles to Form Functionalized 1,8-Naphthyridine and Cyclopentabpyridine Derivatives, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 5 作者  通讯作者
(82) Gold(I)-Catalyzed 1,4-and/or 1,5-Heteroaryl Migration Reactions through Regiocontrolled Cyclizations, CHEMISTRY-A EUROPEAN JOURNAL, 2015, 第 4 作者  通讯作者
(83) Titanium-mediated cross-coupling reactions of 1,3-butadiynes with ��-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization, ORG. CHEM. FRONT., 2014, 第 6 作者
(84) Gold-Catalyzed Cascade Reactions of Furan-ynes with External Nucleophiles Consisting of a 1,2-Rearrangement: Straightforward Synthesis of Multi-Substituted Benzobfurans, CHEMISTRY-A EUROPEAN JOURNAL, 2014, 第 3 作者  通讯作者
(85) Gold-Catalyzed Cascade Reactions of Furan-ynes with External Nucleophiles Consisting of a 1,2-Rearrangement: Straightforward Synthesis of Multi-Substituted Benzobfurans, CHEM.-EUR. J., 2014, 第 3 作者
(86) Titanium-mediated reductive cross-coupling reactions of imines with nitriles: an efficient route for the synthesis of alpha-aminoketones or 1,2-diketones, TETRAHEDRON LETT., 2014, 第 5 作者
(87) 6. Gold(I)-Catalyzed Furan-yne Cyclizations Involving 1,2-Rearrangement: Efficient Synthesis of Functionalized 1-Naphthols and Its Application to the Synthesis of Wailupemycin G., 2014, 第 1 作者  通讯作者
(88) Insertion of Nitriles into Zirconocene 1-aza-1,3-diene Complexes: Chemoselective Synthesis of N-H and N-Substituted Pyrroles, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2014, 第 4 作者  通讯作者
(89) 8. Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes., J. Org. Chem., 2014, 第 1 作者  通讯作者
(90) Gold(I)-Catalyzed Furan-yne Cyclizations Involving 1,2-Rearrangement: Efficient Synthesis of Functionalized 1-Naphthols and Its Application to the Synthesis of Wailupemycin G, CHEM.-EUR. J., 2014, 第 8 作者
(91) Titanium-mediated reductive cross-coupling reactions of imines with nitriles: an efficient route for the synthesis of alpha-aminoketones or 1,2-diketones, TETRAHEDRON LETTERS, 2014, 第 5 作者  通讯作者
(92) Titanium-mediated reductive cross-coupling reactions of imines with nitriles: an efficient route for the synthesis of ��-aminoketones or 1,2-diketones, TETRAHEDRON LETTERS, 2014, 第 5 作者
(93) 5. Insertion of Nitriles into Zirconocene 1-aza-1,3-diene Complexes: Chemoselective Synthesis of N���H and N-Substituted Pyrroles, Angew. Chem. Int. Ed., 2014, 第 1 作者  通讯作者
(94) Gold(I)-Catalyzed Furan-yne Cyclizations Involving 1,2-Rearrangement: Efficient Synthesis of Functionalized 1-Naphthols and Its Application to the Synthesis of Wailupemycin G, CHEMISTRY-A EUROPEAN JOURNAL, 2014, 第 8 作者
(95) Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes, J. ORG. CHEM., 2014, 第 3 作者
(96) 9. Titanium-mediated cross-coupling reactions of 1,3-butadiynes with ��-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization, Org. Chem. Front., 2014, 第 1 作者  通讯作者
(97) Titanium-mediated cross-coupling reactions of 1,3-butadiynes with alpha-iminonitriles to 3-aminopyrroles: observation of an imino aza-Nazarov cyclization, ORGANIC CHEMISTRY FRONTIERS, 2014, 第 6 作者
(98) Gold-Catalyzed Oxidative Reactions of Propargylic Carbonates Involving 1,2-Carbonate Migration: Stereoselective Synthesis of Functionalized Alkenes, JOURNAL OF ORGANIC CHEMISTRY, 2014, 第 3 作者  通讯作者
(99) 7. Gold-Catalyzed Cascade Reactions of Furan-ynes with External Nucleophiles Consisting of a 1,2-Rearrangement: Straightforward Synthesis of Multi-Substituted Benzo[b]furans, Chem. Eur. J., 2014, 第 1 作者  通讯作者
(100) Insertion of Nitriles into Zirconocene 1-aza-1,3-diene Complexes: Chemoselective Synthesis of N-H and N-Substituted Pyrroles, ANGEW. CHEM.-INT. EDIT., 2014, 第 4 作者
(101) Unusual Regioselectivity in the Aldehyde Addition Reactions of Allenyl/Propargyl Zirconium Complexes Derived from gamma-(2-Pyridyl)propargyl Ethers: Synthesis of Multisubstituted alpha-Hydroxyallenes, ORGANOMETALLICS, 2013, 第 3 作者  通讯作者
(102) Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: An efficient route for the synthesis of stereodefined allylic amines, BEILSTEIN J. ORG. CHEM., 2013, 第 3 作者
(103) Environmentally Benign Synthesis of Indeno1,2-bquinolines via an Intramolecular Povarov Reaction, ORGANIC LETTERS, 2013, 第 3 作者  通讯作者
(104) 锆-苯炔参与的金属杂环的形成及其在有机合成中的应用, Construction of Metallacycles via Zirconium-Benzyne Complexes and Its Application in Organic Synthesis, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2013, 第 5 作者
(105) Environmentally Benign Synthesis of Indeno1,2-bquinolines via an Intramolecular Povarov Reaction, ORG. LETT., 2013, 第 3 作者
(106) Construction of Metallacycles via Zirconium-Benzyne Complexes and Its Application in Organic Synthesis, CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2013, 第 5 作者
(107) Gold-catalyzed cascade cycloisomerization of 1,7-diyn-3,6-bis(propargyl carbonate)s: stereoselective synthesis of naphthobcyclobutenes, CHEMICAL COMMUNICATIONS, 2013, 第 5 作者  通讯作者
(108) Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl) stannanes, CHEMICAL COMMUNICATIONS, 2013, 第 3 作者  通讯作者
(109) Gold-Catalyzed Oxidative Rearrangement Involving 1,2-Acyl Migration: Efficient Synthesis of Functionalized Dihydro-gamma-Carbolines from alpha-(2-Indolyl) Propargylic Alcohols and Imines, ANGEWANDTECHEMIEINTERNATIONALEDITION, 2013, 第 3 作者  通讯作者
(110) Titanium-mediated reductive cross-coupling reactions of imines with terminal alkynes: An efficient route for the synthesis of stereodefined allylic amines, BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2013, 第 3 作者  通讯作者
(111) Reactions of Zirconocene Butadiyne or Monoyne Complexes with Nitriles: Straightfoward Synthesis of Functionalized Pyrimidines, ORGANOMETALLICS, 2013, 第 3 作者  通讯作者
(112) Silver-catalyzed cascade cyclization-stannylation of o-alkynylaniline derivatives with 2-tributylstannylfuran: an efficient synthesis of (3-indolyl) stannanes, CHEM. COMMUN., 2013, 第 3 作者
(113) Gold-catalyzed cascade cycloisomerization of 1,7-diyn-3,6-bis(propargyl carbonate)s: stereoselective synthesis of naphthobcyclobutenes, CHEM. COMMUN., 2013, 第 5 作者
(114) Gold-Catalyzed Oxidative Rearrangement Involving 1,2-Acyl Migration: Efficient Synthesis of Functionalized Dihydro-gamma-Carbolines from alpha-(2-Indolyl) Propargylic Alcohols and Imines, ANGEW. CHEM.-INT. EDIT., 2013, 第 3 作者
(115) 螺环哌啶茚的高效合成研究, An Efficient Synthesis of Spiroindenepiperidines, 河南师范大学学报:自然科学版, 2012, 第 3 作者
(116) Highly Efficient Synthesis of cis-3Cumulenic Diols via Zirconocene-Mediated Coupling of 1,3-Butadiynes with Aldehydes, ORGANOMETALLICS, 2012, 第 4 作者  通讯作者
(117) Gold-Catalyzed Cyclizations of (o-Alkynyl)phenoxyacrylates with External Nucleophiles: Regio- and Stereoselective Synthesis of Functionalized Benzoboxepines, ORGANIC LETTERS, 2012, 第 2 作者  通讯作者
(118) Palladium-catalyzed highly efficient synthesis of tetracenes and pentacenes, CHEMICAL COMMUNICATIONS, 2012, 第 3 作者  通讯作者
(119) Gold-Catalyzed Furan/Yne Cyclizations for the Regiodefined Assembly of Multisubstituted Protected 1-Naphthols, JOURNAL OF ORGANIC CHEMISTRY, 2012, 第 5 作者  通讯作者
(120) Nucleophilic Addition of Grignard Reagents to 3-Acylindoles: Stereoselective Synthesis of Highly Substituted Indoline Scaffolds, ORGANIC LETTERS, 2012, 第 3 作者  通讯作者
(121) Gold-Catalyzed Cyclization of 1,6-Diyne-4-en-3-ols: Stannyl Transfer from 2-Tributylstannylfuran Through Au/Sn Transmetalation, ANGEWANDTECHEMIEINTERNATIONALEDITION, 2012, 第 3 作者  通讯作者
(122) Gold-Catalyzed Cascade Cyclizations of 1,6-Diynyl Carbonates to Benzobfluorenes Involving Arylation of Oxocarbenium Ion Intermediates and Decarboxylative Etherification, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2012, 第 3 作者  通讯作者
(123) Facile Synthesis of Fully Substituted Dihydro-beta-carbolines via Bronsted Acid Promoted Cascade Reactions of alpha-Indolyl Propargylic Alcohols with Nitrones, ORGANIC LETTERS, 2012, 第 3 作者  通讯作者
(124) Titanium-mediated cross-coupling reactions of imines with ketones or aldehydes: an efficient route for the synthesis of 1,2-amino alcohols, TETRAHEDRON LETTERS, 2012, 第 2 作者  通讯作者
(125) Unexpected Zirconium-Mediated Multicomponent Reactions of Conjugated 1,3-Butadiynes and Monoynes with Acyl Cyanide Derivatives, CHEMISTRY-A EUROPEAN JOURNAL, 2012, 第 3 作者  通讯作者
(126) 4. Grignard Reagent Acceleration of the Intramolecular Diels-Alder Reaction of Furans with Unactivated Alkynes: Toward Structurally Complex Oxabicyclic Alkenes., CHEM. EUR. J., 2011, 第 1 作者  通讯作者
(127) PIFA/I2促进的顺式烯炔醇的氧化环异构化反应: 多取代的2-酰基呋喃的合成, Highly Efficient Synthesis of Multisubstituted 2-Acyl Furans via PIFA/I(2)-Mediated Oxidative Cycloisomerization of cis-2-En-4-yn-1-ols, SYNLETT, 2011, 第 5 作者  通讯作者
(128) Grignard Reagent Acceleration of the Intramolecular Diels-Alder Reaction of Furans with Unactivated Alkynes: Towards Structurally Complex Oxabicyclic Alkenes, CHEMISTRY-A EUROPEAN JOURNAL, 2011, 第 3 作者  通讯作者
(129) Gold-Catalyzed Ring Opening Cycloamination of Aziridine-Ynes with Nucleophiles: Regio- and Stereoselective Construction of Highly Functionalized 3-Benzazepine Skeletons., Chem. Eur. J., 2011, 第 1 作者  通讯作者
(130) 2. One-Pot Synthesis of Indole-Fused Scaffolds via Gold-Catalyzed Tandem Annulation Reactions of 1,2-Bis(alkynyl)-2-en-1-ones with Indoles, J. Org. Chem., 2011, 第 1 作者  通讯作者
(131) Gold and Bronsted acid catalyzed isomerization of 3cumulenols and 3cumulenones: efficient syntheses of 1,5-dien-3-ynes and furan derivatives, TETRAHEDRON LETTERS, 2011, 第 6 作者  通讯作者
(132) Gold-Catalyzed Deacylative Cycloisomerization Reactions of 3-Acylindole/ynes: A New Approach for Carbazole Synthesis, ORGANIC LETTERS, 2011, 第 3 作者  通讯作者
(133) Gold-Catalyzed Approach to Multisubstituted Fulvenes via Cycloisomerization of Furan/Ynes, J. ORG. CHEM., 2011, 第 2 作者
(134) One-Pot Synthesis of Indole-Fused Scaffolds via Gold-Catalyzed Tandem Annulation Reactions of 1,2-Bis(alkynyl)-2-en-1-ones with Indoles, JOURNAL OF ORGANIC CHEMISTRY, 2011, 第 4 作者  通讯作者
(135) Regio- and Stereoselective Construction of Highly Functionalized 3-Benzazepine Skeletons through Ring-Opening Cycloamination Reactions Catalyzed by Gold, CHEMISTRY-A EUROPEAN JOURNAL, 2011, 第 4 作者  通讯作者
(136) Gold-Catalyzed Cascade Friedel-Crafts/Furan-Yne Cyclization/Heteroenyne Metathesis for the Highly Efficient Construction of Phenanthrene Derivatives, ADVANCED SYNTHESIS & CATALYSIS, 2011, 第 3 作者  通讯作者
(137) 3. Gold-Catalyzed Deacylative Cycloisomerization Reactions of 3-Acylindole/ynes: A New Approach for Carbazole Synthesis, Org. Lett., 2011, 第 1 作者  通讯作者
(138) PIFA/I2促进的顺式烯炔醇的氧化环异构化反应: 多取代的2-酰基呋喃的合成, Highly Efficient Synthesis of Multisubstituted 2-Acyl Furans via PIFA/I(2)-Mediated Oxidative Cycloisomerization of cis-2-En-4-yn-1-ols, SYNLETT, 2011, 第 5 作者  通讯作者
(139) Gold-Catalyzed Approach to Multisubstituted Fulvenes via Cycloisomerization of Furan/Ynes, JOURNAL OF ORGANIC CHEMISTRY, 2011, 第 2 作者  通讯作者
(140) Gold-Catalyzed Intramolecular Indole/Alkyne Cyclization Cascades through a Heterolytic Fragmentation: 1,5-Indole Migration and Allenylation, JOURNAL OF ORGANIC CHEMISTRY, 2010, 第 2 作者  通讯作者
(141) 过渡金属催化的呋喃合成, Transition Metal-Catalyzed Synthesis of Furan Derivatives, 化学进展, 2010, 第 4 作者
(142) 过渡金属催化的呋喃合成, Transition Metal-Catalyzed Synthesis of Furan Derivatives, 化学进展, 2010, 第 4 作者
(143) Stereoselective synthesis of enynones via base-catalyzed isomerization of 1,5-disubstituted-2,4-pentadiynyl silyl ethers or their alcohol derivatives, ORGANIC & BIOMOLECULAR CHEMISTRY, 2010, 第 3 作者  通讯作者
(144) Gold-Catalyzed Benzannulation of 3-Alkoxy-1,5-enynes: Access to Functionalized Benzenes, JOURNAL OF ORGANIC CHEMISTRY, 2010, 第 2 作者  通讯作者
(145) Transition Metal-Catalyzed Synthesis of Furan Derivatives, PROGRESS IN CHEMISTRY, 2010, 第 4 作者
(146) Highly Stereoselective Synthesis of Trisubstituted cis-3Cumulenols from Alkynylated Oxatitanacycles in the Presence of Lewis acids, ORGANOMETALLICS, 2010, 第 2 作者  通讯作者
(147) Aldehyde Addition to 1,3-Butadiyne-Derived Zirconacyclocumulenes: Stereoselective Synthesis of cis-3Cumulenols, ORGANOMETALLICS, 2010, 第 2 作者  通讯作者
(148) Gold-Catalyzed Cyclization of Alkynylaziridines as an Efficient Approach toward Functionalized N-Phth Pyrroles, JOURNAL OF ORGANIC CHEMISTRY, 2010, 第 3 作者  通讯作者
(149) Stereoselective Synthesis of ��-Hydroxyallenes with Multiple Contiguous tereogenic Centers via Aldehyde Addition to alpha-alkenyl-Substituted zirconacyclopentenes., 2009, 第 1 作者  通讯作者
(150) Generation of Allenic/Propargylic Zirconium Complexes and Subsequent Cross-Coupling Reactions: A Facile Synthesis of Multisubstituted Allenes, JOURNAL OF ORGANIC CHEMISTRY, 2009, 第 5 作者  通讯作者
(151) A general and efficient synthesis of substituted furans and dihydrofurans via gold-catalyzed cyclization of ( Z)-2-en-4-yn-1-ols, TETRAHEDRON, 2009, 第 5 作者  通讯作者
(152) Gold-Catalyzed Cascade Friedel-Crafts/Furan-Alkyne Cycloisomerizations for the Highly Efficient Synthesis of Arylated (Z)-Enones or -Enals, ORG. LETT., 2009, 第 4 作者
(153) A facile approach to spirocyclic butenolides through cascade cyclization/oxidative cleavage reactions of ( Z)-enynols catalyzed by gold under dioxygen atmosphere, JOURNAL OF ORGANOMETALLIC CHEMISTRY, 2009, 第 2 作者  通讯作者
(154) Diverse Reactivity of Zirconacyclocumulenes Derived from Coupling of Benzynezirconocenes with 1,3-Butadiynes towards Acyl Cyanides: Synthesis of Indeno2,1-bpyrroles or 3Cumulenones, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 第 4 作者  通讯作者
(155) An Efficient Domino Approach for the Synthesis of Multisubstituted Pyrroles via Gold/Silver-Catalyzed Amination/Cycloisomerization of (Z)-2-En-4-yn-1-ols, ADVANCED SYNTHESIS & CATALYSIS, 2009, 第 6 作者  通讯作者
(156) Generation of Allenic/Propargylic Zirconium Complexes and Subsequent Cross-Coupling Reactions: A Facile Synthesis of Multisubstituted Allenes, J. ORG. CHEM., 2009, 第 5 作者
(157) Stereoselective Synthesis of beta-Hydroxyallenes with Multiple Contiguous Stereogenic Centers via Aldehyde Addition to alpha-Alkenyl-Substituted Zirconacyclopentenes, JOURNAL OF ORGANIC CHEMISTRY, 2009, 第 5 作者  通讯作者
(158) Gold-Catalyzed Cascade Friedel-Crafts/Furan-Alkyne Cycloisomerizations for the Highly Efficient Synthesis of Arylated (Z)-Enones or -Enals, ORGANIC LETTERS, 2009, 第 4 作者  通讯作者
(159) Iron-Catalyzed Cascade Arene-Aldehyde Addition/Cyclizations for the Highly Efficient Synthesis of Xanthenes and Its Analogous: Observation of a C-C Bond Cleavage in Indole-Based Triarylmethanes, JOURNAL OF ORGANIC CHEMISTRY, 2009, 第 3 作者  通讯作者
(160) Gold-Catalyzed Intermolecular Reactions of (Z)-Enynols with Indoles for the Construction of Dihydrocycloheptabindole Skeletons through a Cascade Friedel-Crafts/Hydroarylation Sequence, ADVANCED SYNTHESIS & CATALYSIS, 2009, 第 4 作者  通讯作者
(161) A general and efficient synthesis of substituted fluorenes and heterocycle-fused indenes containing thiophene or indole rings utilizing a Suzuki���Miyaura coupling and acid-catalyzed Friedel���Crafts reactions as key steps, TETRAHEDRON, 2008, 第 5 作者  通讯作者
(162) Dialkyltitanium-mediated titanation of conjugated 1,3-butadiynes and its coupling reactions with aldehydes: a facile synthesis of stereodefined enynes and trans-enynols, TETRAHEDRON LETTERS, 2008, 第 2 作者  通讯作者
(163) A facile Zr-mediated multicomponent approach to arylated allylic alcohols and its application to the synthesis of highly substituted indenes and spiroindenes, ORGANIC & BIOMOLECULAR CHEMISTRY, 2008, 第 2 作者  通讯作者
(164) BX促进的烯炔醇的串联氧化/环化反应:2-酰基呋喃的合成, New Synthetic Approach for the Construction of Multisubstituted 2-Acyl Furans by the IBX-Mediated Cascade Oxidation/Cyclization of cis-2-En-4-yn-1-ols (IBX=2-lodoxybenzoic Acid), CHEM.-EUR. J., 2008, 第 3 作者
(165) New Synthetic Approach for the Construction of Multisubstituted 2-Acyl Furans by the IBX-Mediated Cascade Oxidation/Cyclization of cis-2-En-4-yn-1-ols (IBX=2-Iodoxybenzoic Acid), CHEMISTRY-A EUROPEAN JOURNAL, 2008, 第 3 作者  通讯作者
(166) New Synthetic Approach for the Construction of Multi-Substituted 2-Acyl Furans via IBX-Mediated Cascade Oxidation/Cyclization of cis-2-En-4-yn-1-ols., 2008, 第 1 作者  通讯作者
(167) Carbon-Carbon Bond Formation of alpha-Alkynylzirconacyclopentenes via Cyclization or a Cu/Pd-Mediated Cyclization/Cross-Coupling Sequence with Aryl Iodides, ORGANOMETALLICS, 2008, 第 4 作者  通讯作者
(168) Highly efficient bronsted acid-catalyzed cycloisomerizations of alkynes bearing bis(acetoxy) groups to indenyl ketones, ADVANCED SYNTHESIS & CATALYSIS, 2008, 第 1 作者  通讯作者
(169) General and direct synthesis of 3-aminoindolizines and their analogues via Pd/Cu-catalyzed sequential cross-coupling/cycloisomerization reactions, ORGANIC LETTERS, 2007, 第 1 作者  通讯作者
(170) Gold-catalyzed direct amination of allylic alcohols, SYNLETT, 2007, 第 3 作者  通讯作者
(171) Gold-catalyzed multicomponent synthesis of aminoindolizines from aldehydes, amines, and Alkynes under solvent-free conditions or in water, ORGANIC LETTERS, 2007, 第 2 作者  通讯作者
(172) Studies on the zirconium-mediated alkyne-aldehyde coupling reactions: a facile synthesis of stereodefined allylic alcohols and (Z)-2-en-4-yn-l-ols, TETRAHEDRON, 2007, 第 4 作者  通讯作者
(173) Highly efficient synthesis of functionalized indolizines and indolizinones by copper-catalyzed cycloisomerizations of propargylic pyridines, JOURNAL OF ORGANIC CHEMISTRY, 2007, 第 5 作者  通讯作者
(174) Cleavage of a carbon-carbon triple bond via gold-catalyzed cascade cyclization/oxidative cleavage reactions of (Z)-enynols with molecular oxygen, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 第 1 作者  通讯作者
(175) Highly stereoselective synthesis of TMS-, alkyl-, or aryl-substituted cis-3cumulenols via alpha-alkynylated zirconacyclopentenes, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 第 1 作者  通讯作者
(176) A new domino process initiated by acetylide addition onto trans-1,2-dibenzoyl-3,5-cyclohexadienes: Observation of sequential C-C, C-O bond formation/cleavage reactions, SYNLETT, 2006, 第 1 作者  通讯作者
(177) 由炔基锂化合物对羰基化合物的加成所引发的新型多米诺反应, A new domino process initiated by acetylide addition onto trans-1,2-dibenzoyl-3,5-cyclohexadienes: Observation of sequential C-C, C-O bond formation/cleavage reactions 3-ylidene-2,3-dihydrofurans; benzophenones, SYNLETT, 2006, 第 1 作者
(178) I2/K3PO4 体系促进的2-(1-炔基)-2-烯-1-酮的亲电环化反应:多取代碘代呋喃的高效合成法研究, Electrophilic Cyclization of 2-(1-Alkynyl)-2-alken-1-ones Using I2/K3PO4 System: An Efficient Synthesis of Highly Substituted Iodofurans., ORG. LETT., 2005, 第 1 作者
(179) 有机锆促进的炔烃的杂环化反应:含有分子内异喹啉配位基团的八员氧杂锆杂环的形成。, Heterocyclized carbometalation of alkynes: unexpected formation of eight-membered oxazirconacycles with an intramolecular coordinated isoquinoline moiety., ORGANOMETALLICS, 2004, 第 3 作者

科研活动

   
科研项目
( 1 ) 碳-碳和碳-杂原子键的不对称构建, 参与, 中国科学院计划, 2023-11--2028-10
( 2 ) 铜催化硼试剂参与的N-活化的杂环类化合物的高选择性转化反应研究, 负责人, 国家任务, 2023-01--2026-12
( 3 ) 微生物药物(中间 体)的高效制备, 参与, 国家任务, 2022-12--2025-11
( 4 ) 镍/光双催化的反应研究, 负责人, 研究所自主部署, 2022-09--2024-08
( 5 ) 过渡金属金及镍催化的炔烃的高效转化反应研究, 负责人, 地方任务, 2018-05--2021-04
( 6 ) 镍催化的氰基化反应研究, 负责人, 国家任务, 2018-01--2021-12
( 7 ) 微纳结构有机分子催化材料催化机制及纳米效应研究, 参与, 国家任务, 2016-07--2021-06
( 8 ) 金催化的扩环反应研究, 负责人, 国家任务, 2016-01--2019-12
( 9 ) 化学键活化与可控性重组研究, 参与, 国家任务, 2015-01--2017-12
( 10 ) 金催化的若干新型串联反应研究, 负责人, 国家任务, 2014-01--2017-12
( 11 ) 国家自然科学基金委杰出青年基金, 负责人, 国家任务, 2012-01--2015-01
参与会议
(1)Versatile Reaction Modes of a-Functionalized Zirconacycles Derived by Coupling Reactions with 1,3-Butadiynes or Enynes   第十六届全国金属有机化学学术讨论会    刘元红   2010-10-22