General

齐莉 女 汉族 硕导 化学研究所


Li Qi  

femal 

supervisor for master students

Institute of Chemistry, Chinese Academy of Sciences


Email: qili@iccas.ac.cn
Telephone:   +86-10-82627290
Address:  No. 2 Zhongguancun Beiyijie, Beijing, P.R. China
Postcode: ​100190

Research Areas


   Analytical Chemistry



Experience

Education:

Ph.D                             Chemistry department, Hebei University, Hebei, P.R. China

B.S.                               Chemistry department, Sun Yat-Sen University, Guangdong, P.R. China

1994-1995                   William Harper College, Chicago, IL, USA

Work Experience

2002.03-present        Institute of ChemistryChinese Academy of Sciences (ICCAS), associate professor / professor


Teaching Experience

2016.03-present     Prof., Teach Analytical Chemistry ​in University of Chinese Academy of Sciences


Honors & Distinctions

(1)   The First Class Award of China Analytical Instrument Association for Science and Technology award (2012, 2016)

(2)   The Second Class Award of Beijing Municipal Sciences and Technology (1998)

(3)   The Third Class Award of Beijing Municipal Sciences and Technology (1994)






2007.01-present  Board member, Beijing Society of Chromatography

2020.04-present  Editor board, Journal of Analytical Science and Technology

Publications

 In recent years, as correspondence author, published 103 SCI papers in Analytical Chemistry and other journals.

Authorized 9 patents

                                               ​

Papers

Selected publication

1.

Construction   of degradable liposome-templated microporous metal-organic frameworks with high   degree-of-freedom space for enzymes, Chinese Chemical Letters,   2024, 35, 109812.

Corresponding author

2.

Confinement-induced   biocatalytic activity enhancement of light- and thermo-responsive   polymer@enzyme@MOF composites, ACS Applied Materials & Interfaces,   2024, 16, 36953-36961.

Corresponding author

3

Dual stimuli-responsive   enzyme@metal-organic framework-polymer composites towards enhanced catalytic   performance for visual detection of glucose, ACS Applied Bio Materials,   2024, 7, 325-331.

Corresponding author

4

Thermo-responsive   polymer-modified metal-organic frameworks as soft-rigid enzyme-reactors for enhancement   of enzymolysis efficiency using a controllable embedding protocol, Journal of Materials   Chemistry B, 2023, 11, 6428-6434.

Corresponding author

5

Dual-stimuli-responsive   polymer vesicles for regulation of enzymolysis efficiency in a cascade reaction,   Chemistry-An   Asian Journal, 2023, 18, e202300285.

Corresponding author

6

Redox-responsive   polymer nanoreactors based on methionine sulfoxide for monitoring of cell   adherence, Analytical   Chemistry, 2022, 94, 11807.

Corresponding author

7

In   situ determination of sialic acid on cell-surface with pH-regulated polymer   enzyme nanoreactor, Analytical Chemistry, 2021, 93, 7317.

Corresponding author

8

Simultaneous   monitoring of intracellular temperature and norepinephrine variation by fluorescent   probes during norepinephrine reuptake, Analytical Chemistry,   2021, 93, 14743.

Corresponding author

9

Enzyme immobilization   on a pH-responsive porous polymer membrane for enzymatic kinetics study, Chinese   Chemical Letters, 2021, 32, 3195.

Corresponding author

10

Design   of switchable enzyme carriers based on stimuli-responsive porous polymer   membranes for bio-applications, ACS Applied Bio Materials, 2021, 4, 4706.

Corresponding author

11

Thermoresponsive   porous polymer membrane as a switchable enzyme reactor for D-amino acid   oxidase kinetics study, ACS Applied Bio Materials, 2021, 4, 966.

Corresponding author

12

Selective capture and   in-situ controllable detection of D-glucose in cerebral systems, Analytical   Chemistry, 2020, 92, 4445.

Corresponding author

13

Simultaneous monitoring   of temperature and Ca2+ concentration variation by fluorescent   polymer during intracellular heat production, Analytical Chemistry,   2020, 92, 8579.

Corresponding author

14

Enzyme reactor based on   reversible pH controlled catalytic polymer porous membrane, ACS   Applied Materials & Interfaces, 2019, 11, 15133.

Corresponding author

15

Simultaneous monitoring   of mitochondrial temperature and ATP fluctuation using fluorescent probes in   living cells, Analytical Chemistry, 2018, 90, 12553.

Corresponding author

16.

On-line proteolysis and   glycopeptide enrichment with thermo-responsive porous polymer membrane   reactors for nanoflow liquid chromatography-tandem mass spectrometry, Analytical   Chemistry, 2018, 90, 3124.

Corresponding author

17.

Preparation of   polymer@AuNPs with droplets approach for sensing serum copper ions, Analytical   Chemistry, 2017, 89, 2080.

Corresponding author

18.

Ratiometric fluorescent   pattern for sensing proteins using aqueous polymer-pyrene/g-cyclodextrin   inclusion complexes, Analytical Chemistry, 2016, 88,   1821.

Corresponding author

19.

Folic acid-conjugated   fluorescent polymer for up-regulation folate receptor expression study via   targeted imaging of tumor cells, Biosensors & Bioelectronics,   2016, 78, 147.

Corresponding author

20.

Construction of   fluorescent polymeric nano thermometers for intracellular temperature   imaging: A review, Biosensors & Bioelectronics,   2016, 85, 403.

Corresponding author

21.

Ratiometric fluorescent   polymeric thermometer: for thermogenesis investigation in living cells, Analytical   Chemistry, 2015, 87, 10535.

Corresponding author

22.

Ratiometric fluorescent   probe based on gold nanoclusters and alizarin red-boronic acid for monitoring   glucose in brain microdialysate, Analytical Chemistry, 2014, 86,   9758.

Corresponding author

23.

Construction of D-amino   acid oxidase reactor based on magnetic nanoparticles modified by reactive   polymer and its application in screening enzyme inhibitors, ACS   Applied Materials & Interfaces, 2014, 6, 12979.

Corresponding author

24.

Poly(2-vinyl-4,4-dimethylazlactone-functionalized   magnetic nanoparticles as carriers for enzyme immobilization and its   application, ACS Applied Materials & Interfaces, 2014, 6, 21346.

Corresponding author

25.

Novel oligo(ethylene glycol)-based   molecularly imprinted magnetic nanoparticles for thermally modulated capture   and release of lysozyme, ACS Applied Materials & Interfaces,   2014, 6, 17289.

Corresponding author

26.

Thermoresponsive   oligo(ethylene glycol)-based polymer brushes on polymer monolith for   all-aqueous chromatography, ACS Applied Materials & Interfaces,   2013, 5, 12441.

Corresponding author

27.

Facile one-pot synthesis   of L-proline-stabilized fluorescent gold nanoclusters and its application as   sensing probes for serum iron, Biosensors & Bioelectronics,   2013, 49, 249.

Corresponding author

28.

Folic   acid-functionalized fluorescent gold nanoclusters with polymer as linker for   cancer cells imaging, Chemical Communications, 2013, 49,   8030.

Corresponding author

29.

Reactive polymer   function as a versatile toolbox for construction of multifunctional   superparamagnetic nanocomposites, Chemistry-A European Journal,   2012, 18, 13755.

Corresponding author

30.

Thermal responsive   fluorescent block copolymer for intracellular temperature sensing, Journal   of Materials Chemistry, 2012, 22, 11543.

Corresponding author

Patents

  • Authorized Patents

    1. Li Qi, Xiao-Yu Mu, Juan Qiao, Preparation of a novel D-amino acid oxidase-based enzyme reactor, CN ZL201310594025.4

    2. Li Qi, Hai-Zhi Zhang, Xiao-Yu Mu, Juan Qiao, Lan-Qun Mao, Amino acid liquid ions as the ligands for chiral ligand exchange capillary electrophoresis application, CN ZL201210229429.9

    3. Li Qi, Jun Yang, Hui-Min Ma, Construction of porous cellulose membrane based microchip and its application, CN ZL201210122279.1

Research Interests


1.    Capillary electrophresis for chiral separation and enzyme kinetics

2.    Preparation of polymer-based micro/nano materials and its application in sensing and cell imaging

3.   Preparation of polymer monolith and its application in bio-chromatography

Collaboration

2016.7-2018.6 NSFC International Co-operation Project (Yonsei University, Korea, Prof. Meyong Hee Moon)

Students

已指导学生

韩志强                                  博士研究生  070302-分析化学  

杨    俊                                 博士研究生  070302-分析化学  

张荣月                                  博士研究生  070302-分析化学  

辛培勇                                  博士研究生  070302-分析化学  

乔    娟                                 博士研究生  070302-分析化学  

魏晓奕                                  博士研究生  070302-分析化学  

姚春荷                                  博士研究生  070302-分析化学  

张海枝                                  博士研究生  070302-分析化学  

沈    莹                                 博士研究生  070302-分析化学  

李雅萍                                  博士研究生  070302-分析化学  

木肖玉                                  博士研究生  070302-分析化学  

姜俊芳                                  硕士研究生  070302-分析化学  

李    楠                                 博士研究生  070302-分析化学  


现指导学生

沈吉                                     硕士研究生  070302-分析化学 

Nasir Ali                              博士研究生  070302-分析化学

Muhammad Ali Tajwar       硕士研究生  070302-分析化学

Rubina Jabeen                    硕士研究生  070302-分析化学

Education