张智军 男 博导 苏州纳米技术与纳米仿生研究所
电子邮件:zjzhang2007@sinano.ac.cn
通信地址:苏州工业园区独墅湖高教区若水路398号
邮政编码:215123 
课题组网页:http://nanosafety.sinano.ac.cn/

研究领域

纳米生物医学

招生信息

   
招生专业
070304-物理化学(含:化学物理)
071009-细胞生物学
招生方向
新型纳米载药体系
纳米生物影像技术
纳米材料与干细胞

教育背景

1995-01--1998-03 日本关西学院大学 博士
1984-09--1987-07 中国西北大学 硕士
1980-09--1984-07 中国西北大学 学士
学历
-- 研究生
学位
-- 博士

工作经历

1987-1994在西北大学化学系任助教和讲师。1998-1999年在北京大学化学与分子工程学院从事博士后研究。1999-2001年日本名古屋大学物质科学国际研究中心,日本学术振兴会(JSPS)特别研究员。2001-2004年在加拿大国家研究院Steacie 分子科学研究所,加拿大国家自然科学与工程理事会(NSERC)研究员。2004-2005年在加拿大McGill大学生物医学工程系,研究助理。2006-2007在加拿大国家研究院工业材料研究所,研究助理。2007年11月回国受聘中国科学院苏州纳米技术与纳米仿生研究所, 任研究员、博士生导师。

专利与奖励

   
专利成果
(1) 一种多孔道核壳型磁金复合纳米粒子的制备方法,发明,2009,第1作者,专利号:200910183934.2
(2) 一种金属与石墨烯复合催化剂的制备方法,发明,2012,第1作者,专利号:20101022784.7
(3) 用于巨噬细胞相关疾病靶向给药的药物载体及其制备方法,发明,2009,第1作者,专利号:200910183928.7
(4) 生理条件下稳定的纳米氧化石墨烯及其制备方法,发明,2012,第1作者,专利号:200910183927.2
(5) 一种磁载药纳米粒子的制备方法,发明,2011,第1作者,专利号:200910183933.8

出版信息

   
发表论文
(1) Directed osteogenic differentiation of mesenchymal stem cell in three-dimensional biodegradable methylcellulose-based scaffolds,Colloids and Surfaces B: Biointerfaces,2015,通讯作者
(2) Enhanced proliferation and osteogenic differentiation of mesenchymal stem cells ,ACS Appl. Mater. Interfaces,2015,通讯作者
(3) Manganese doped iron oxide theranostic nanoparticles for combined T1 magnetic resonance imaging and photothermal therapy,ACS Appl. Mater. Interfaces,2015,通讯作者
(4) Near-infrared fluorescent cyanine-grafted graphene oxide with enhanced intrinsic photothermal performance for in vivo tumor eradication,Advanced Functional Materials,2015,通讯作者
(5) Removal and recycling of ppm level methylene blue from natural water with graphene oxide,RSC Advances,2015,通讯作者
(6) Rational Design and Synthesis of γFe2O3@Au Magnetic Gold Nanoflowers for Efficient Cancer Theranostics,Adv. Mater.,2015,通讯作者
(7) Accessing in vivo toxicity of graphene materials: current methods and future outlook,Nanomedicine,2014,通讯作者
(8) Ultra-small graphene oxide-supported gold nanoparticles as adjuvant improves humoral and cellular immunity in mouse,Advanced Functional Materials,2014,通讯作者
(9) In vitro and in vivo toxicity of graphene quantum dots,Biomaterials,2014,通讯作者
(10) PEGylated carbon nanoparticles for efficient in vitro photothermal cancer therapy,J. Mater. Chem. B,2014,通讯作者
(11) Intracellular Tracking of Drug Release from Graphene Oxide by Surface-Enhanced Raman Spectroscopy,Nanoscale,2013,通讯作者
(12) Combination of TNF-α and Graphene Oxide-Loaded BEZ235 to Enhance Apoptosis of PIK3CA Mutant Colorectal Cancer Cells,J. Mater. Chem. B,2013,通讯作者
(13) Synthesis, protein delivery, and in vitro and in vivo toxicity of a biodegradable poly(aminoester),Toxicology Research,2013,通讯作者
(14) Transferrin modified graphene oxide for glioma-targeted drug delivery: in vitro and in vivo evaluations,ACS Appl. Mater. Interfaces,2013,通讯作者
(15) PEGylated Reduced Graphene Oxide as a Superior ssRNA Delivery System,J. Mater. Chem. B,2013,通讯作者
(16) Graphene Oxide Based Theranostic Platform for T1-Weighted Magnetic Resonance Imaging and Drug Delivery,ACS Appl. Mater. Interfaces,2013,通讯作者
(17) PEGylated Graphene Oxide-Mediated Protein Delivery for Cell Function Regulation,ACS Appl. Mater. Interfaces,2012,通讯作者
(18) Rotavirus Capsid Surface Protein VP4-Coated Fe3O4 Nanoparticles: A Theranostic Nanoplatform for Efficient Cellular Imaging and Drug Delivery,Biomaterials,2012,通讯作者
(19) Mechanism of cellular uptake of graphene oxide studied by surface-enhanced Raman spectroscopy,Small,2012,通讯作者
(20) Biomedical Applications of Graphene,Theranostics,2012,通讯作者
(21) Self-Assembled Virus-like Particles from Rotavirus Structural Protein VP6 for Targeted Drug Delivery, Bioconjugate Chem.,2011,通讯作者
(22) Enhanced chemotherapy efficacy by sequential delivery of siRNA and anticancer drugs using PEI–grafted graphene oxide,Small,2011,通讯作者
(23) Polyethylenimine- Functionalized Graphene Oxide as an Efficient Gene Delivery Vector,J. Mater. Chem,2011,通讯作者
(24) Polyamidoamine-Grafted Multiwalled Carbon Nanotubes for Gene Delivery: Synthesis, Transfection and Intracellular Trafficking,Bioconjugate Chem,2011,通讯作者
(25) Controlled assembly of Fe3O4 magnetic nanoparticles on graphene oxide,Nanoscale,2011,通讯作者
(26) Composites of Aminodextran-Coated Fe3O4 Nanoparticles and Graphene Oxide for Cellular Magnetic Resonance Imaging,ACS Applied Materials and Interfaces,2011,通讯作者
(27) Functional graphene oxide as nanocarriers for controlled loading and targeted delivery of mixed anticancer drugs,Small,2010,通讯作者
(28) Nanocomposites of size-controlled gold nanoparticles and graphene oxide: Formation and applications in SERS and catalysis, Nanoscale,2010,通讯作者
(29) Synthesis of a novel magnetic drug delivery system composed of doxorubicin-conjugated Fe3O4 nanoparticle cores and a PEG-functionalized porous silica shell,Chem Comm. ,2010,通讯作者

科研活动

   
科研项目
(1) 诱导性前脑神经祖细胞体内微环境的组分解析、条件优化和功能模拟,参与,国家级,2014-01--2018-08
(2) 基于快速成型技术的新型神经组织工程支架材料研发,参与,国家级,2013-02--2016-01
(3) 基于金属纳米颗粒-氧化石墨烯复合体系的表面增强拉曼基底的构筑及其用于细胞与药物相互作用研究,主持,国家级,2011-01--2013-12

指导学生

已指导学生

张立明  博士研究生  070304-物理化学  

陈卫红  博士研究生  070304-物理化学  

涂小龙  硕士研究生  070304-物理化学  

曹玉华  博士研究生  071009-细胞生物学  

沈贺  博士研究生  071009-细胞生物学  

张萌欣  博士研究生  070304-物理化学  

现指导学生

宋赛杰  硕士研究生  070304-物理化学  

刘晓云  硕士研究生  071009-细胞生物学  

付寒  博士研究生  071009-细胞生物学