Magnetic resonance imaging and spectroscopy

Molecular MRI

Metabolic imaging

2009-2013  Bachelor,  Huazhong University of Science and Technology, China

2013-2017  Ph. D,        National University of Singapore, Singapore

2018-2020    Post-doctoral research fellow, Johns Hopkins University School of Medicine, USA

2020-Now     Associate Professor,                 Shenzhen Institute of Advanced Technology, CAS

（1） Zhou et al., Mechanism and quantitative assessment of saturation transfer for water-based detection of the aliphatic protons in carbohydrate polymers., Magn Reson Med, 2021.
（2） Zhou et al., Magnetic resonance imaging of glycogen using its magnetic coupling with water, Proceedings of the National Academy of Sciences, 2020.

Metabolic disorders are the hallmarks in many diseases. Dr. Zhou's current research is mainly on developing MR approaches to target important molecualr components and their metabolic processes in vivo. But MR spectroscopic methods are quite limited by their low signal sensitivity. Chemical exchange saturation transfer (CEST) MRI is a fast growing approach that allows enhanced detection of molecules at low concentration. Dr. Zhou's lab has been exploring CEST-related meachanisms, methodology and applications. And at the same time, he is also interested in other MR techniques and applications. 

（1）Detection of ionic bonding using IMMOBILISE MRI and theoretical description of the relayed NOE transfer mechanism   ISMRM,   2021-05-15
（2）Mapping glycogen concentration in vivo based on the nuclear Overhauser enhancement (NOE) with water (glycoNOE)   ISMRM.   2020-08-08
（3）In vivo MRI of mouse liver glycogen based on the nuclear Overhauser enhancement (NOE) with water (glycoNOE)   ISMRM   2019-05-14

（1） The ISMRM Summa Cum Laude Merit Award. 2020