YONG Q. ZHANG, PhD, doctoral supervisor, Institute of Genetics and Developmental Biology Chinese Academy of Sciences
Email: yqzhang@genetics.ac.cn
Fax: 86 10 6480 7611
Address: No.1 West Beichen Road, Chao Yang District Beijing, China
Postcode: 100101
Research Areas
Education
1985 - 1991 Beijing Agricultural University. Ph.D. Biochemistry & Molecular Biology
1980 - 1985 Huazhong Agricultural University, Wuhan. B.Sc. Veterinary Medicine
Experience
Work Experience
Study on the molecular and genetic mechanisms of intellectual disability and synapse development and function in Drosophila.
1998 - 2003: with Dr Kendal Broadie, first at the University of Utah, then at Vanderbilt University
Postdoctoral Associate: neurological functions of fragile X protein; genes involved in synaptic development and function in Drosophila.
1995 - 1997: with Professor Michael Ashburner, Fellow of the Royal Society. Department of Genetics, University of Cambridge, England.
Postdoctoral Associate: genome mapping within the European Drosophila Genome Project; molecular and genetic analyses of stress sensitive B, a behavioral mutant gene.
1994: with Prof. Ab van Kammen in the Department of Molecular Biology, Wageningen University, the Netherlands.
Visiting scientist: map-based cloning of disease resistance genes from tomato.
1992 - 1995: Principle investigator in the Institute of Microbiology, Chinese Academy of Sciences, Beijing, China.
Molecular characterization of fruit-ripening related genes and manipulating fruit ripening by transgenes
Teaching Experience
Molecular Genetics
Editorial duties
2. Ad hoc reviewer for
Human Molecular Genetics
Developmental Biology
Journal of Neuroscience
Journal of Cell Science
PLoS Genetics
Development
Honors & Distinctions
2. State Council Expert for Special Allowance (2012).
3. A "hundred people plan" researcher of Chinese Academy of Sciences (2005).
4. The National Science Fund for Distinguished Young Scholars (2005).
5. Kennedy Center for Research on Human Development at Vanderbilt University (2003).
6. FRAXA Research Foundation at www.fraxa.org (2001-2002).
Publications
Papers
2. A presynaptic role for the cytomatrix protein GIT in synaptic vesicle recycling. Cell Reports, 2014. Non corresponding author
3. Drosophila Acyl-CoA synthetase long-chain family member 4 inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling, Journal of Neuroscience, 2014 (Featured article). Corresponding author
4. Microtubule-severing protein katanin regulates neuromuscular junction development and dendritic elaboration in Drosophila. Development, 2014. Corresponding author
5. Brain tumor regulates neuromuscular synapse growth and endocytosis in Drosophila by suppressing Mad expression. Journal of Neuroscience, 2013. Corresponding author
6. Drosophila cyfip regulates synaptic development and endocytosis by suppressing filamentous actin assembly. PLoS Genet. Corresponding author
7. HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila. Proc Natl Acad Sci USA, 2013, Corresponding author
8. RIM Promotes Calcium Channel Accumulation at Active Zones of the Drosophila Neuromuscular Junction. Journal of Neuroscience, 2012. Non Corresponding author
9. Drosophila FMRP participates in the DNA damage response by regulating G2/M cell cycle checkpoint and apoptosis. Human Molecular Genetics, 2012. Co-corresponding Author
10. Drosophila acyl-CoA synthetase long-chain family member 4 regulates axonal transport of synaptic vesicles and is required for synaptic development and transmission. Journal of Neuroscience, 2011. Corresponding author
11. Drosophila FMRP regulates microtubule network formation and axonal transport of mitochondria. Human Molecular Genetics, 2011. Corresponding author
12. Drosophila CG10527 mutants are resistant to juvenile hormone and its analog methoprene. Biochemical and Biophysical Research Communications, 2010. Corresponding author
13. Distinct pre- and postsynaptic dismantling processes of Drosophila neuromuscular junctions during metamorphosis. Journal of Neuroscience, 2010. Corresponding author
14. Drosophila twinfilin is required for cell migration and synaptic endocytosis. Journal of Cell Science, 2010. Co-corresponding Author
Students
Graduated students
Liu Zhiwei Doctor 071008 - Developmental biology
Zhang Haiying Doctor 071008 - Developmental biology
Wang Dan Doctor 071008 - Developmental biology
Zhi Hui Doctor 071008 - Developmental biology
Chen Yan Doctor 071008 - Developmental biology
Jiang Fangfang Doctor 071008 - Developmental biology
Liu Zhihua Doctor 071008 - Developmental biology
Liu Wei Doctor 071008 - Developmental biology
Xiong Ying Doctor 071008 - Developmental biology
Shi Wenwen Doctor 071008 - Developmental biology
Zhao Lu Doctor 071008 - Developmental biology
Zhao Guoli Doctor 071008 - Developmental biology
Huang Yan Doctor 071008 - Developmental biology
Huang Sheng Master 071006 - Neurobiology
Currently learning students
Wu Song Doctor 071008 - Developmental biology
Li Wenhua Doctor 071006 - Neurobiology
Zhao Kai Doctor 071006 - Neurobiology
Jia Mingyue Doctor 071006 - Neurobiology
Meng Danqing Doctor 071006 - Neurobiology
Li Meixiang Master 071007 - Genetics
Hong Huilin Master 071006 – Neurobiology
Chen Mo Doctor 071006 - Neurobiology
Zhao Hui Doctor 071006 - Neurobiology
Guo Meizhi Master 071008 - Developmental biology
Li Tingting Master 071006 – Neurobiology
Wang Qiqi Master 071006 – Neurobiology
Ding Haitao Doctor 071006 - Neurobiology
Md. Shafayat Hossain Doctor 071006 - Neurobiology
Elsayed Metwally mahmoud Doctor 071006 - Neurobiology