Ethnobotany
Medicinal Chemistry

From 9/2003 to 7/2006: Kunming Institute of Botany, Chinese Academy of Sciences; Ph.D. in Botany (Phytochemistry)
From 9/2000 to 7/2003: Northwest A&F University; M.S. in Veterinary Medicine
From 9/1987 to 7/1991: Yunnan Agricultural University; B.S. in Veterinary Medicine

   

From 1/2010 to present: Associate Professor, Kunming Institute of Botany, Chinese Academy of Sciences
From 3/2013 to 4/2014: Visiting Scholar, University of North Carolina at Chapel Hill, USA
From 10/2010 to 3/2011: Visiting Scholar, Okayama University, Japan
From 8/2006 to 12/2009: Assistant Professor, Kunming Institute of Botany, Chinese Academy of Sciences
From 8/1991 to 8/2000: Veterinarian, Bureau of Agriculture, Weixin County, Yunnan, China

   

[1] Zhang L, Yi P, Yan H, Li X-N, Xia M-Y, Yang J, Luo J-F, He Y-Q, Wang Y-H. Five new 2-(2-phenylethyl)chromone derivatives and three new sesquiterpenoids from the heartwood of Aquilaria sinensis, an aromatic medicine in China. Nat. Prod. Bioprosp., 2022, 12: 2.

[2] Yang J, Hu D-B, Xia M-Y, Luo J-F, Li X-Y, Wang Y-H. Bioassay‑guided isolation of cytotoxic constituents from the flowers of Aquilaria sinensis. Nat. Prod. Bioprosp., 2022, 12: 11.

[3] Chen Y-F, Zhang D-D, Hu D-B, Li X-N, Luo J-F, Duan X-Y, Zhang Y-N, Wang Y-H. Alkaloids and flavonoids exert protective effects against UVB-induced damage in a 3D skin model using human keratinocytes. Results Chem., 2022, 4: 100298.

[4] Zhang R, Wang Y, Yang J, Long C-L Medicinal Plants Used by Ethnic Groups in Yunnan. In Lau, Clara Bik-San, Long, Chun-Lin eds. Medicinal Plants and Mushrooms of Yunnan Province of China; CRC Press, 2021.

[5] Zhang F-M, Wang Y-H, Zhao P, Yu F-Q. A new p-terphenyl derivative from the fruiting bodies of Sarcodon imbricatus (L.) P. Karst. Nat. Prod. Res., 2021, 35: 2482.

[6] Zhang FM, Wang YH, Yu FQ, Hua Y. Tricholomines A and B, two new amides from the fruiting bodies of Tricholoma bakamatsutake. Magn. Reson. Chem., 2021, 59: 587.

[7] Zhang D, Arunachalam K, Wang Y, Zhang Y, Yang J, Hein PP, Mon AM, Li J, Inta A, Yang X. Evaluation on antidiabetic properties of medicinal plants from Myanmar. Sci. World J., 2021, 2021: 1424675.

[8] Yang Y-L, Song B-Q, Long J-Y, Fang D-H, Hu D-B, Song N, Luo J-F, Zeng J-M, Wang Y-H. Antifungal constituents from Nicotiana tabacum with the Wz locus infected by Phytophthora nicotianae. Results Chem., 2021, 3: 100196.

[9] Yang J, Luo J, Gan Q, Ke L, Zhang F, Guo H, Zhao F, Wang Y. An ethnobotanical study of forage plants in Zhuxi County in the Qinba mountainous area of central China. Plant Divers., 2021, 43: 239.

[10] Wei S-Y, Hu D-B, Xia M-Y, Luo J-F, Yan H, Yang J-H, Wang Y-S, Wang Y-H. Sesquiterpenoids and 2-(2-phenylethyl)chromone derivatives from the resinous heartwood of Aquilaria sinensis. Nat. Prod. Bioprosp., 2021, 11: 545.

[11] Wang Y-H. Traditional uses and pharmacologically active constituents of Dendrobium plants for dermatological disorders: A review. Nat. Prod. Bioprosp., 2021, 11: 465.

[12] Wang Y-H. Traditional uses, chemical constituents, pharmacological activities, and toxicological effects of Dendrobium leaves: A review. J. Ethnopharmacol., 2021, 270: 113851.

[13] Tibpromma S, Zhang L, Karunarathna SC, Du T-Y, Phukhamsakda C, Rachakunta M, Suwannarach N, Xu J, Mortimer PE, Wang Y-H. Volatile constituents of endophytic fungi isolated from Aquilaria sinensis with descriptions of two new species of Nemania. Life, 2021, 11: 363.

[14] San TT, Wang Y-H, Hu D-B, Yang J, Zhang D-D, Xia M-Y, Yang X-F, Yang Y-P. A new sesquineolignan and four new neolignans isolated from the leaves of Piper betle, a traditional medicinal plant in Myanmar. Bioorg. Med. Chem. Lett., 2021, 31: 127682.

[15] Li X, Munir S, Xu Y, Wang Y, He Y. Combined mass spectrometry-guided genome mining and virtual screening for acaricidal activity in secondary metabolites of Bacillus velezensis W1. RSC Adv., 2021, 11: 25441.

[16] He Q, Hu D-B, Zhang L, Xia M-Y, Yan H, Li X-N, Luo J-F, Wang Y-S, Yang J-H, Wang Y-H. Neuroprotective compounds from the resinous heartwood of Aquilaria sinensis. Phytochemistry, 2021, 181: 112554.

[17] Chen W-Y, Yang T, Yang J, Qiu Z-C, Ding X-Y, Wang Y-H, Wang Y-H. Wild plants used by the Lhoba people in Douyu Village, characterized by high mountains and valleys, in southeastern Tibet, China. J. Ethnobiol. Ethnomed., 2021, 17: 46.

[18] Yang J, Chen W-Y, Fu Y, Yang T, Luo X-D, Wang Y-H, Wang Y-H. Medicinal and edible plants used by the Lhoba people in Medog County, Tibet, China. J. Ethnopharmacol., 2020, 249: 112430.

[19] Xia C, Chen L, Sun W, Yan R, Xia M, Wang Y, Yang D. Total saponins from Paris forrestii (Takht) H. Li. show the anticancer and RNA expression regulating effects on prostate cancer cells. Biomed. Pharmacother., 2020, 121: 109674.

[20] Qian Q-G, Gong L-M, Yang S-H, Zhao B-Q, Cai J, Zhang Z-J, Wang Y-H, Zhou X-J. Two new compounds from Carpesium abrotanoides. Phytochem. Lett., 2020, 40: 5.

[21] Chai D, Yuan J, Zhu X, Zeng Y, Yang R, Chen Y, Wang Y, Zhou Y. Total saponins from Paris forrestii reverse multidrug resistance of MCF-7/ADM cells by suppression of P-gp via ERK signaling pathway. Biol. Pharm. Bull., 2020, 43: 1823.

[22] Aung TTT, Xia M-Y, Hein PP, Tang R, Zhang D-D, Yang J, Yang X-F, Hu D-B, Wang Y-H. Chemical constituents from the whole plant of Cuscuta reflexa. Nat. Prod. Bioprospect., 2020, 10: 337.

[1] Yang J, Wang Y, Luo J, Xia M, Zhang Y. Aquilaria sinensis extract useful in medicinal composition for preparing medicine for treating and preventing cancer, preferably lung cancer, cervical cancer, human neuroblastoma, ovarian cancer, leukemia, prostatic cancer and breast cancer. CN113262258-A.

[2] Wang Y, Zhang L, Luo J, Yang J. New white wood fragrant aquilarotetrol PES-22 is 1-(5-(1,2-dihydroxy-ethyl)-2,5-dihydro-furan-2-yl)-5-phenyl-pentane-1,3- diol compound, used for preparation of medicine for preventing and treating neurodegenerative diseases. CN113861135-A.

[3] Wang Y, Zhang D, Luo J, Li S. Use of Dendrobium officinale leaf total alkaloid PXS-115 in preparing cosmetic preservative, food preservative, antibacterial cosmetic and medicine, preparing medicine for treating skin aging, skin inflammation and skin cancer, preparing medicine or cosmetic for treating or preventing skin disease. CN113679653-A.

[4] Wang Y, Zhang D, Chen Y, Luo J, Hu D, Guo Y. Use of 1-(beta-carboline-1-yl)-3,4,5-trihydroxy-1-pentanone and/or 1-hydroxymethyl-beta-carboline for preparing anti-UVB radiation preparation, and anti-UVB radiation cosmetic, and medicine for treating and preventing skin aging caused by UVB radiation, skin inflammation and skin cancer. CN113616646-A.

[5] Wang Y, Weng Z, Lin H, Zhang X, Zhang Q, Li J, Liang L, Li X, He Q, Yang J, Luo J. Use of agilawood tetraol PFC24 in preparing medicine for preventing and treating vascular dementia disease. CN113694055-A.

[6] Wang Y, Chen Y, Luo J, Duan X, Wang Y. Use of vicenin-1 in preparing anti-UVB radiation medicine composition or/and cosmetic, improving activity of human epidermal keratinocytes after UVB irradiation, treating and preventing skin aging caused by UVB radiation, skin inflammation and skin cancer. CN113842383-A.

[7] Yang J, Wang Y, Luo J, Xia M, Li X, Hu D. Extracting cucurbitacin E, sakuranetin, and cucurbitacin B from ethyl acetate extraction part of Aquilaria sinensis extract comprises e.g. pulverizing and extracting dried flowers of Aquilaria sinensis, making extract into suspension and post-processing. CN113817013-A.

Ethnobotany

Medicinal chemistry

Natural products

Cardiovascular diseases

Nervous system diseases

Kunming Medical University

University of North Carolina at Chapel Hill

China Pharmaceutical University

Minzu University of China

Yunnan Agricultural University

Guizhou Medical University

已指导学生

柯镭喻  硕士研究生  085235-制药工程  

唐蓉  硕士研究生  078001-药物化学  

张璐  硕士研究生  085238-生物工程  

杨韬  硕士研究生  071001-植物学  

邱天雯  硕士研究生  071001-植物学  

现指导学生

杨莹莉  硕士研究生  071001-植物学  

陈小宇  硕士研究生  071001-植物学  

李海寅  硕士研究生  105500-药学  

贾建科  硕士研究生  105500-药学