Sun Qinchao, Ph.D., associate professor, doctoral supervisor, overseas high-level talent of the "Peacock Plan" in Shenzhen. In 2016, he obtained a doctoral degree in Physics and Chemistry from the University of Geneva. From 2017 to 2019, he worked as a postdoctoral researcher at Stanford University and joined SIAT as an associate professor in the same year. His main research direction is the development and application of biomedical diagnostic and therapeutic materials, design and mechanism research of small molecule luminescent probes, etc.
For the first time, he observed the 3dd state of ruthenium complexes through experimental means and successfully finely controlled the lifespan of this state. The corresponding achievements were published in the Journal of the American Chemical Society, Chemical Science, and Coordination Chemical Reviews.
For the first time, he achieved chemiluminescence in the near-infrared second region and conducted detailed theoretical and experimental research on the mechanism of chemiluminescence of glow sticks. He proposed the electronic transfer mechanism-molecular orbital swing model for this type of chemiluminescence, correcting long-standing misconceptions about this type of chemiluminescence and the view that it is impossible to achieve near-infrared second region luminescence through a single luminescent molecule. The relevant research was published as a cover in Chemical Communications.
To date, he has published more than 20 academic papers, including over 10 papers as the first author or corresponding author, and has applied for 6 patents. As the project leader, he has led projects such as the National Natural Science Foundation, Youth Project, Shenzhen Basic Research, and has also participated as a research backbone in projects such as the development of major national scientific research instruments funded by the National Natural Science Foundation.
Research Areas
With the knowledge of physical chemistry, we study the laws of nature and the processes of life in various ways:
Fluorescent materials for cellular and in vivo activity analysis, such as cell tracking, biological imaging, neuronal activity, protein function, and more.
Nanomaterials for understanding the mechanisms of tumor treatment, including light-controlled release, photodynamic therapy, drug delivery systems, and targeted drug delivery.
Education
2012-08--2016-07 Ph.D. University of Geneva, Switzerland
2007-09--2011-01 Master, Dalian Institute of Chemical Physics, Chinese Academy of Sciences
2003-09--2007-07 Undergraduate, Shandong University
Publications
18. Zong Chang, Chenchen Liu, Like Guo, Bingxin Shu, Huageng Liang*, Jie Ding*, Xiaoping Zhang*, Qinchao Sun*. Single-dye NIR-II chemiluminescence system for H2O2 imaging, Chemical Communication, 2023,59, 6171-6174
17. Zong Chang, Liangjian Liu, Jingying Zhai, Chenchen Liu, Xiao Wang, Chengbo Liu,* Xiaojiang Xie,* Qinchao Sun*. Molecular Electronic Coupling-Induced Photoacoustics for NIR-I/II Duplex in Vivo Imaging, Chemistry of Materials, 2023, 35, 1335-1344.
16. Zong Chang; Chenchen Liu; Shubi Zhao; Jiaqi Chen; Xiaoping Zhang; Hanyu Tian; Qinchao Sun ; Near Infrared-II Fluorescent protein for In-vivo Imaging, bioRxiv, 2022, 2022.03.04.482971
15. Qiang Liu, Jiangwei Tian, YeTian, Qinchao Sun, Dan Sun, Dewen Liu, Feifei Wang, Haijun Xu, Guoliang Ying Jigang Wang Ali K.Yetisen NanJiang, Thiophene donor for NIR-II fluorescence imaging-guided photothermal/photodynamic/chemo combination therapy, Acta Biomaterialia, 127, 287-297
14. Jingqin Chen, Adam C. Sedgwick, Sajal Sen‡, Yaguang Ren, Qinchao Sun, Calvin Chau, Jonathan F. Arambula , Tridib Sarma*, Liang Song, Jonathan L. Sessler *, Chengbo Liu*, Expanded porphyrins: functional photoacoustic imaging agents that operate in the NIR-II region, Chem. Sci., 2021, 12, 9916-9921
13. Shubi Zhao#, Yiqun Luo#, Zong Chang, Chenchen Liu, Tong Li, Lu Gan, Yong Huang*, Qinchao Sun*, BSA-Coated Gold Nanorods for NIR-II Photothermal Therapy，Nanoscale Research Letters volume 16, Article number: 170 (2021)
12. Qiang Liu#, Jiangwei Tian#, Ye Tian#, Qinchao Sun#, Dan Sun, Feifei Wang, Haijun Xu*, Guoliang Ying*, Jigang Wang*, Ali K. Yetisen, Nan Jiang* Near-Infrared-II Nanoparticles for Cancer Imaging of Immune Checkpoint Programmed Death-Ligand 1 and Photodynamic/Immune Therapy，ACS Nano 2021, 15, 1, 515–525
11. Zong Chang#, Feng Liu#, Liang Wang, Mengying Deng, Chunhua Zhou, Qinchao Sun*, Jun Chu*. Near-infrared dyes, nanomaterials and proteins, Chinese Chemical Letters, 2019, 30,1856-1882
10. Feifei Wang#, Hao Wan#, Zhuoran Ma#, Yeteng Zhong, Qinchao Sun, Ye Tian, Liangqiong Qu, Haotian Du, Mingxi Zhang, Lulin Li, Huilong Ma, Jian Luo, Yongye Liang, Wen Jung Li, Guosong Hong, Lianqing Liu，Hongjie Dai. Light-sheet microscopy in the near-infrared II window,Nature Methods,2019,16,545-552
9. Zhuoran Ma#,Hao Wan,Weizhi Wang,Xiaodong Zhang,Takaaki Uno,Qianglai Yang, Jingying Yue, Hongpeng Gao, Yeteng Zhong,Ye Tian,Qinchao Sun,Yongye Liang,Hongjie Dai*,A theranostic agent for cancer therapy and imaging in the second near-infrared window,Nano Research,2019,12(2),273-279
8. Qinchao Sun#,Bogdan Dereka, Eric Vauthey, Latévi M. Lawson Daku, Andreas Hauser*, Ultrafast transient IR spectroscopy and DFT calculations of ruthenium (II) polypyridyl complexes, Chemical Science. 2017(1), 8, 223-230.
7. Thomas Biet#, Thomas Cauchy, Qinchao Sun, Jie Ding, Andreas Hauser*, Patric Oulevey, Thomas Bürgi, Denis Jacquemin, Nicolas Vanthuyne, Jeanne Crassous, Narcis Avarvari*, Triplet state CPL active helicene-dithiolene platinum bipyridine complexes. Chemical Communications. 2017, 53(66), 9210-9213.
6. Qinchao Sun#, Sandra Mosquera-Vazquez, Yan Suffren, Jihane Hankache, Nahid Amstutz, Latévi Max Lawson Daku, Eric Vauthey, Andreas Hauser*,On the role of ligand-field states for the photophysical properties of ruthenium (II) polypyridyl complexes. Coordination Chemistry Reviews. 2015, 282–283, 87-99.
5. Iuliia Nazarenko#,Flavia Pop, Qinchao Sun, Andreas Hauser, Francesc Lloret, Miguel Julve, Abdelkrim El-Ghayoury, Narcis Avarvari*, Structural, Photophysical and Magnetic Properties of Transition Metal Complexes Based on the Dipicolylamino-chloro-1,2,4,5-tetrazine Ligand. Dalton Transactions. 2015, 44(19), 8855-8866.
4. Qinchao Sun#,Sandra Mosquera-Vazquez#,Latev́i Max Lawson Daku,Laure Gueńeé, Harold A. Goodwin, Eric Vauthey, Andreas Hauser*, Experimental Evidence of Ultrafast Quenching of the 3MLCT Luminescence in Ruthenium (II) Tris-bipyridyl Complexes via a 3dd State. Journal of American Chemical Society. 2013, 135(37), 13660-13663.
3. Nikolaos Gomopoulos#, Cornelis Lütgebaucks, Qinchao Sun, Carlos Macias-Romero, Sylvie Roke*, Label-free second harmonic and hyper Rayleigh scattering with high efficiency. Optics Express. 2013, 21(1), 815-821.
2. Qinchao Sun#, Jianyong Liu*, Yan Hao, Xichuan Yang, Volume-conserved Twist Excited-state of π-Conjugated Molecules. Chinese Journal of Chemical Physics. 2010, 23(6), 637-642.
1. Qinchao Sun#, DaCheng Feng*, DFT Study and Quantitative Structure-activity Relationship for Cephalosporin Derivatives. Chemical Journal of Chinese Universities. 2007, 28(4), 696-699.
Students
We are currently accepting applications for PhD students, master's students, joint training students, visiting students, and interns.
The areas of study or specialization include, but are not limited to: organic materials, nanomaterials, drug delivery, physical chemistry, cellular imaging, and fluorescent molecules.
Alternatively, if you have a keen interest in our related fields, please feel free to contact us via email:
Email: qchao.sun@siat.ac.cn