纳米生物材料，药物递送，干细胞示踪和治疗材料，高通量制备技术

材料化学和物理

080501-材料物理与化学
0805J1-纳米科学与技术
0805J7-仿生界面交叉科学

纳米生物材料
干细胞示踪和治疗材料
高通量合成技术

2008-08--2013-07   中国科学院上海硅酸盐研究所   博士
2004-09--2008-07   中国科学技术大学   本科

2013年-2016年，中国科学院上海硅酸盐研究所，助理研究员 

2018/01-2018/12，芬兰赫尔辛基大学/图尔库埃博学术大学，中科院公派访问学者 

2016年至今，中国科学院上海硅酸盐研究所，副研究员

2013-09~现在, 中国科学院上海硅酸盐研究所, 副研究员

   

（1） 上海市青年科技启明星, 省级, 2019

[1] 兰正义, 马明, 陈航榕. 一种用于高通量微反应器合成的预混/注射集成进样系统. CN: CN215415480U, 2022-01-04.

[2] 马明, 舒一盟, 陈航榕, 于会珠, 申杰, 张衡. 具有核磁共振成像与干细胞保护功能的超顺磁颗粒-钴原卟啉自组装体及其制备方法. CN: CN113769117A, 2021-12-10.

[3] 马明, 兰正义, 陈航榕. 基于微流控芯片的高通量材料合成设备及方法. CN: CN113019262A, 2021-06-25.

[4] 张衡, 马明, 陈航榕, 舒一盟. 一种可实时测定pH并加热的自动加料搅拌装置. CN: CN213253937U, 2021-05-25.

[5] 张衡, 马明, 陈航榕, 陈潜. 一种固液混合物料筛分收集装置. CN: CN213253334U, 2021-05-25.

[6] 马明, 兰正义, 魏晨阳, 陈航榕. 一种基于机械搅拌模式的数控高通量粉体制备设备. CN: CN213254411U, 2021-05-25.

[7] 马明, 申杰, 陈航榕, 于会珠, 舒一盟. 一种改性葡聚糖包覆的核壳型复合纳米颗粒及其制备方法. CN: CN111297829A, 2020-06-19.

[8] 陈世雄, 马明, 陈航榕, 施剑林. 一种类红细胞形状的介孔氧化硅纳米材料及其制备方法. CN: CN106927472A, 2017-07-07.

[9] 马明, 陈航榕, 施剑林. 一种方解石相球形多孔碳酸钙颗粒及其制备方法. CN: CN106564923A, 2017-04-19.

[10] 王世革, 陈航榕, 施剑林, 马明. 一种MoS 2 纳米片的可控合成及同步表面修饰方法. CN: CN104030360B, 2016-08-17.

[11] 马明, 陈航榕, 施剑林. 一种磁性中空纳米球及其制备方法. CN: CN104485191A, 2015-04-01.

[12] 马明, 陈航榕, 施剑林, 贾晓庆. 有机无机复合纳米囊泡剂及其制备方法. CN: CN103735533A, 2014-04-23.

[13] 张坤, 陈航榕, 施剑林, 陈雨, 王霞, 马明. 功能化改性的中空介孔或核/壳介孔二氧化硅纳米颗粒的制备方法. CN: CN102530969A, 2012-07-04.

[14] 马明, 陈航榕, 施剑林, 陈雨. 一种镶嵌金纳米棒的介孔硅基纳米复合材料的合成方法. CN: CN102078617A, 2011-06-01.

   

[1] Shen, Jie, Ma, Ming, Shafiq, Muhammad, Yu, Huizhu, Lan, Zhengyi, Chen, Hangrong. Microfluidics-Assisted Engineering of pH/Enzyme Dual-Activatable ZIF@Polymer Nanosystem for Co-Delivery of Proteins and Chemotherapeutics with Enhanced Deep-Tumor Penetration. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION[J]. 2022, 61(14): http://dx.doi.org/10.1002/anie.202113703.
[2] Yu, Huizhu, Ma, Ming, Jiang, Liping, Shen, Jie, Xue, Fengfeng, Chen, Hangrong. A metal protoporphyrin-induced nano-self-assembly for potentiating photothermal therapy by depleting antioxidant defense systems. CHEMICAL ENGINEERING JOURNAL[J]. 2021, 420: http://dx.doi.org/10.1016/j.cej.2021.129769.
[3] Yu, Huizhu, Ma, Ming, Liang, Kaicheng, Shen, Jie, Lan, Zhengyi, Chen, Hangrong. A self-assembled metal-polyphenolic nanomedicine for mild photothermal-potentiated chemodynamic therapy of tumors. APPLIED MATERIALS TODAY[J]. 2021, 25: http://dx.doi.org/10.1016/j.apmt.2021.101235.
[4] Xue, Fengfeng, Du, Wenxian, Chen, Shixiong, Ma, Ming, Kuang, Yichen, Chen, Jufeng, Yi, Tao, Chen, Hangrong. Hypoxia-Induced Photogenic Radicals by Eosin Y for Efficient Phototherapy of Hypoxic Tumors. ACS APPLIED BIO MATERIALS[J]. 2020, 3(12): 8962-8969, [5] Du, Wenxian, Liu, Tianzhi, Xue, Fengfeng, Chen, Yu, Chen, Qian, Luo, Yu, Cai, Xiaojun, Ma, Ming, Chen, Hangrong. Confined nanoparticles growth within hollow mesoporous nanoreactors for highly efficient MRI-guided photodynamic therapy. CHEMICAL ENGINEERING JOURNAL[J]. 2020, 379: http://dx.doi.org/10.1016/j.cej.2019.122251.
[6] Chen, ShiXiong, Ma, Ming, Xue, Fengfeng, Shen, Shuzhan, Chen, Qian, Kuang, Yichen, Liang, Kaicheng, Wang, Xiuli, Chen, Hangrong. Construction of microneedle-assisted co-delivery platform and its combining photodynamic/immunotherapy. JOURNAL OF CONTROLLED RELEASE[J]. 2020, 324: 218-227, http://dx.doi.org/10.1016/j.jconrel.2020.05.006.
[7] Shen, Jie, Ma, Ming, Zhang, Hongbo, Yu, Huizhu, Xue, Fengfeng, Hao, Nanjing, Chen, Hangrong. Microfluidics-Assisted Surface Trifunctionalization of a Zeolitic Imidazolate Framework Nanocarrier for Targeted and Controllable Multitherapies of Tumors. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 12(41): 45838-45849, http://dx.doi.org/10.1021/acsami.0c14021.
[8] Yao, Minghua, Shi, Xiaojing, Zuo, Changjing, Ma, Ming, Zhang, Lu, Zhang, Hongbo, Li, Xin, Yang, GuoYuan, Tang, Yaohui, Wu, Rong. Engineering of SPECT/Photoacoustic Imaging/Antioxidative Stress Triple-Function Nanoprobe for Advanced Mesenchymal Stem Cell Therapy of Cerebral Ischemia. ACS APPLIED MATERIALS & INTERFACES[J]. 2020, 12(34): 37885-37895, http://dx.doi.org/10.1021/acsami.0c10500.
[9] Shen, Jie, Shafiq, Muhammad, Ma, Ming, Chen, Hangrong. Synthesis and Surface Engineering of Inorganic Nanomaterials Based on Microfluidic Technology. NANOMATERIALS[J]. 2020, 10(6): https://doaj.org/article/d72493103b70485287ebf7614afbc5af.
[10] Ma, Ming, Shu, Yimeng, Tang, Yaohui, Chen, Hangrong. Multifaceted application of nanoparticle-based labeling strategies for stem cell therapy. NANO TODAY[J]. 2020, 34: http://dx.doi.org/10.1016/j.nantod.2020.100897.
[11] Liu, Tianzhi, Wan, Qian, Luo, Yu, Chen, Mengjie, Zou, Chao, Ma, Ming, Liu, Xin, Chen, Hangrong. On-Demand Detaching Nanosystem for the Spatiotemporal Control of Cancer Theranostics. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(18): 16285-16295, https://www.webofscience.com/wos/woscc/full-record/WOS:000467781100005.
[12] Chen, Qian, Luo, Yu, Du, Wenxian, Liu, Zhuang, Zhang, Shengjian, Yang, Jiahui, Yao, Heliang, Liu, Tianzhi, Ma, Ming, Chen, Hangrong. Clearable Theranostic Platform with a pH-Independent Chemodynamic Therapy Enhancement Strategy for Synergetic Photothermal Tumor Therapy. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(20): 18133-18144, http://dx.doi.org/10.1021/acsami.9b02905.
[13] Qi, Shengcai, Zhang, Pengfei, Ma, Ming, Yao, Minghua, Wu, Jinjin, Makila, Ermei, Salonen, Jarno, Ruskoaho, Heikki, Xu, Yuanzhi, Santos, Helder A, Zhang, Hongbo. Cellular Internalization-Induced Aggregation of Porous Silicon Nanoparticles for Ultrasound Imaging and Protein-Mediated Protection of Stem Cells. SMALL[J]. 2019, 15(1): http://dx.doi.org/10.1002/smll.201804332.
[14] Chen, Qian, Liu, Tianzhi, Chen, Shixiong, Luo, Yu, Ma, Ming, Xue, Fengfeng, Zhang, Linlin, Bao, Weichao, Chen, Hangrong. Targeted Therapeutic-Immunomodulatory Nanoplatform Based on Noncrystalline Selenium. ACS APPLIED MATERIALS & INTERFACES[J]. 2019, 11(49): 45404-45415, http://dx.doi.org/10.1021/acsami.9b15774.
[15] Zhang, Qiuhong, Chen, Jingwen, Ma, Ming, Wang, Han, Chen, Hangrong. A Bioenvironment-Responsive Versatile Nanoplatform Enabling Rapid Clearance and Effective Tumor Homing for Oxygen-Enhanced Radiotherapy. CHEMISTRY OF MATERIALS[J]. 2018, 30(15): 5412-5421, http://ir.sic.ac.cn/handle/331005/24731.
[16] Ming Ma. Mesopore-Induced Aggregation of Cobalt Protoporphyrin for Photoacoustic Imaging and Antioxidant Protection of Stem Cell. Advanced Functional Materials. 2018, [17] Qin, Tao, Qin, Weiwei, Ma, Ming, Zhang, Dawei, Hu, Shugang, Zhang, Peng, Nikolajeff, Fredrik, Engqvist, Hakan. A novel rapid synthesis, characterization and applications of calcium phosphate nanospheres from Baltic seawater. CERAMICS INTERNATIONAL[J]. 2018, 44(8): 9076-9079, http://dx.doi.org/10.1016/j.ceramint.2018.02.114.
[18] Wang, Ning, Ma, Ming, Luo, Yu, Liu, Tianzhi, Zhou, Peng, Qi, Shengcai, Xu, Yuanzhi, Chen, Hangrong. Mesoporous Silica Nanoparticles-Reinforced Hydrogel Scaffold together with Pinacidil Loading to Improve Stem Cell Adhesion. CHEMNANOMAT[J]. 2018, 4(7): 631-641, http://dx.doi.org/10.1002/cnma.201800026.
[19] 马明, 颜燕宏, 漆超, 祁胜财, 陈世雄, 尚光伟, 汪饶饶, 陈航榕. 多孔方解石相碳酸钙微球的自组装合成及口腔修复应用. 中国科学：材料科学（英文版）[J]. 2017, 60(6): 516-528, http://lib.cqvip.com/Qikan/Article/Detail?id=672473574.
[20] Liu, Tianzhi, Zhang, Nan, Wang, Zhigang, Wu, Meiying, Chen, Yu, Ma, Ming, Chen, Hangrong, Shi, Jianlin. Endogenous Catalytic Generation of O-2 Bubbles for In Situ Ultrasound-Guided High Intensity Focused Ultrasound Ablation. ACS NANO[J]. 2017, 11(9): 9093-9102, http://dx.doi.org/10.1021/acsnano.7b03772.
[21] Wan, Gang, Ma, Ming, Jia, Alec Yi, Chen, Lisong, Chen, Yu, Cui, Xiangzhi, Chen, Hangrong, Shi, Jianlin. A 3D hierarchical assembly of optimized heterogeneous carbon nanosheets for highly efficient electrocatalysis. JOURNAL OF MATERIALS CHEMISTRY A[J]. 2016, 4(30): 11625-11629, http://www.irgrid.ac.cn/handle/1471x/1176913.
[22] Ma, Ming, Yan, Fei, Yao, Minghua, Wei, Zijun, Zhou, Dongliang, Yao, Heliang, Zheng, Hairong, Chen, Hangrong, Shi, Jianlin. Template-Free Synthesis of Hollow/Porous Organosilica-Fe3O4 Hybrid Nanocapsules toward Magnetic Resonance Imaging-Guided High-Intensity Focused Ultrasound Therapy. ACS APPLIED MATERIALS & INTERFACES[J]. 2016, 8(44): 29986-29996, http://www.irgrid.ac.cn/handle/1471x/1161581.
[23] 蔡晓军, 马明, 陈航榕, 施剑林. 普鲁士蓝在肿瘤诊断和治疗中的研究进展. 科技导报[J]. 2016, 34(2): 18-26, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5654717&detailType=1.
[24] Cai, Xiaojun, Gao, Wei, Zhang, Linlin, Ma, Ming, Liu, Tianzhi, Du, Wenxian, Zheng, Yuanyi, Chen, Hangrong, Shi, Jianlin. Enabling Prussian Blue with Tunable Localized Surface Plasmon Resonances: Simultaneously Enhanced Dual-Mode Imaging and Tumor Photothermal Therapy. ACS NANO[J]. 2016, 10(12): 11115-11126, http://www.irgrid.ac.cn/handle/1471x/1161560.
[25] 牟娟, 陈雨, 马明, 张坤, 魏晨阳, 陈航榕, 施剑林. Cu2-xS/脂质体纳米复合物的制备及其多模式成像与热疗研究（英文）. 中国科学：材料科学（英文版）[J]. 2015, 294-301, http://lib.cqvip.com/Qikan/Article/Detail?id=83677765504849534852484854.
[26] 何敏瑜, 冉海涛, 马明, 贾晓庆, 王志刚. 超声介导DNA门控空心介孔二氧化硅纳米粒的药物释放. 中国医学影像技术[J]. 2015, 31(2): 191-195, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5361288&detailType=1.
[27] 何敏瑜, 冉海涛, 周頔, 马明, 王志刚. 载Bi_2S_3液态氟碳纳米粒的制备及体外多功能显影. 中国介入影像与治疗学[J]. 2014, 11(12): 808-812, http://sciencechina.cn/gw.jsp?action=detail.jsp&internal_id=5328140&detailType=1.
[28] 王霞, 陈航榕, , 马明, 陈雨, 张坤, 施剑林. 金纳米粒子负载的介孔氧化硅基多功能材料用于超声成像、诱导细胞凋亡和肿瘤消融治疗. BIOMATERIALS[J]. 2013, 34(8): 2057-, http://ir.sic.ac.cn/handle/331005/5142.
[29] 潘黎敏, 何前军, 刘佳男, 陈雨, 马明, 张琳琳, 施剑林. TAT肽链嫁接的介孔二氧化硅纳米颗粒的细胞核靶向药物传递. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY[J]. 2012, 134(13): 5722-5725, http://www.irgrid.ac.cn/handle/1471x/659122.
[30] 张坤, 陈航榕, , 陈雨, 马明, 王霞, 王立军, , 施剑林. 原位疏水法制备改性的中空或是rattle-型中空介孔二氧化硅纳米颗粒. JOURNAL OF MATERIALS CHEMISTRY[J]. 2012, 22(25): 12553-12561, http://www.irgrid.ac.cn/handle/1471x/659154.
[31] 何前军, 马明, 魏晨阳, 施剑林. 用于荧光成像与疏水性药物同步传输的介孔碳@硅-二氧化硅纳米诊治体系. BIOMATERIALS[J]. 2012, 33(17): 4392-4402, http://ir.sic.ac.cn/handle/331005/3510.
[32] 马明, 陈航榕, 陈雨, 张坤, 王霞, 崔香枝, 施剑林. 透明质酸改性介孔二氧化硅材料用于癌症靶向治疗. JOURNAL OF MATERIALS CHEMISTRY[J]. 2012, 22(12): 5615-5621, http://www.irgrid.ac.cn/handle/1471x/659105.
[33] 马明, 陈航榕, 陈雨, 王霞, 陈风, 崔香枝, 施剑林. 介孔二氧化硅基纳米复合材料用于热化联合治疗的研究. BIOMATERIALS[J]. 2012, 33(3): 989-998, http://www.irgrid.ac.cn/handle/1471x/659070.
[34] 陈雨, 马明, 何前军, 张琳琳, 施剑林, 陈航榕, 孙阳, 郑元义, 曾得平, 李发琪, 张盛箭, 王霞, 张坤. 多功能介孔复合纳米胶囊用于高性能核磁共振引导下的高强度聚焦超声手术治疗. ANGEWANDTE CHEMIE INTERNATIONAL EDITION[J]. 2011, 52(50): 12505-12509, http://www.irgrid.ac.cn/handle/1471x/635996.
[35] 陈雨, 陈航榕, 马明, 陈风, 郭利民, 张玲霞, 施剑林. 双壁球形/纺锤形介孔纳米结构用于亲/疏水抗癌药物的输运. JOURNAL OF MATERIALS CHEMISTRY[J]. 2011, 21(14): 5292-5298, http://www.irgrid.ac.cn/handle/1471x/635913.

   

（ 1 ） 智能多孔药物载体的微流控构建：基础问题与转化应用, 主持, 省级, 2019-05--2022-05
（ 2 ） 青年促进会, 主持, 部委级, 2020-01--2023-12
（ 3 ） 高通量微流控合成设备, 主持, 市地级, 2020-04--2021-05