牛丽丽-中国科学院大学-UCAS

基本信息

牛丽丽女中国科学院深圳先进技术研究院
电子邮件： ll.niu@siat.ac.cn
通信地址：深圳市南山区西丽镇学苑大道1068号
邮政编码：518055

研究领域

超声神经调控；超声生物力学成像

招生信息

招生专业

083100-生物医学工程
081203-计算机应用技术
081002-信号与信息处理

招生方向

超声血流成像，超声弹性成像，超声神经调控
超声成像算法
超声信号处理

教育背景

2009-09--2012-11   中国科学院大学   博士
2007-09--2009-07   东北大学   硕士
2003-09--2007-07   沈阳师范大学   学士

学历

博士

学位

博士

专利与奖励

代表性专利：

(1) 郑海荣; 周慧; 牛丽丽; 郭瑞彪; 孟龙; 李永川; 苏敏; 黄继卿; 钱明；清醒动物超声神经调控装置，授权日：2019/6/4，授权号：ZL201710138442.6

(2) 郑海荣;牛丽丽;王丛知;钱明;肖杨;孟龙，一种获得用于发射穿颅聚焦超声的超声发射序列的方法及系统，授权日：2018-03-23，授权号：ZL201410829230.9

(3) 郑海荣;黄小伟;牛丽丽;孟龙;周伟;钱明;肖杨，一种多阵元换能器的阵元选择装置、方法和超声刺激系统，授权日：2019/3/12，授权号：ZL201610289024.2

(4) 郑海荣;周慧;牛丽丽;孟龙;夏向向;张金钮;郭瑞彪;苏敏，一种自动收线的超声神经调控装置，申请号：CN201710636418.5

(5) 郑海荣;周伟;孟龙;王凯悦;牛丽丽;黄小伟;蔡飞燕;李飞;王辰，一种超声神经调控系统，授权日：2019-07-19，授权号：ZL201610803573.7

奖励：

· 2016 广东省科学技术奖

· 2015 中科院科技促进发展奖

奖励信息

（1）基于剪切波的定量超声弹性成像技术与应用, 一等奖, 省级, 2016
（2）高端医学影像技术与装备及其产业化团队, 二等奖, 部委级, 2015

专利成果

[1] 牛丽丽, 李飞, 林争荣, 郑海荣, 孟文. 全息超声跨颅与神经环路调控系统及其设计方法. PCT/CN2022/076195, 2022-02-14.
[2] 郑海荣, 周伟, 孟龙, 牛丽丽, 林争荣, 黄小伟, 邹俊杰. 超声唤醒系统. CN: CN112657033A, 2021-04-16.
[3] 郑海荣, 刘秀芳, 孟龙, 王宇辰, 徐礼胜, 周伟, 牛丽丽, 黄小伟. 一种基因转染系统及方法. CN: CN110760534B, 2021-04-09.
[4] 郑海荣, 林争荣, 牛丽丽, 孟龙, 周伟, 孟文. 多焦点超声波的生成装置及生成方法. CN: CN112604191A, 2021-04-06.
[5] 蔡飞燕, 夏向向, 郑海荣, 牛丽丽, 周慧. 超声针灸装置. CN: CN110478632B, 2021-03-23.
[6] 牛丽丽, 郑海荣, 孟龙, 邹俊杰, 易沙沙, 黄小伟, 陈厚民基, 钟永盛, 周伟. 闭环超声刺激控制排尿功能的装置. CN: CN112494831A, 2021-03-16.
[7] 郑海荣, 周慧, 牛丽丽, 孟龙, 夏向向, 庞娜. 一种免疫系统调控方法及超声免疫治疗装置. CN: CN112473026A, 2021-03-12.
[8] 郑海荣, 牛丽丽, 庞娜, 孟龙, 孟文. 超声白发诊疗设备及计算机可读存储介质. CN: CN112155593A, 2021-01-01.
[9] 郑海荣, 黄小伟, 牛丽丽, 孟龙, 邹俊杰, 陈厚民基, 林争荣, 周伟, 易沙沙. 刺激信号的发生方法、发生装置及终端设备. CN: CN112156360A, 2021-01-01.
[10] 郑海荣, 牛丽丽, 庞娜, 孟龙, 孟文, 周慧. 一种基于超声波的人体增强方法及装置. CN: CN111973894A, 2020-11-24.
[11] 郑海荣, 孟龙, 陈卫兴, 牛丽丽, 崔笑宇. 一种生物样本分选方法、声表面波微流控芯片、系统、终端以及存储介质. CN: CN111925934A, 2020-11-13.
[12] 郑海荣, 牛丽丽, 钟永盛, 孟龙, 邹俊杰, 黄小伟, 易沙沙. 穿戴式超声神经刺激装置及系统. CN: CN111921102A, 2020-11-13.
[13] 郑海荣, 牛丽丽, 钟永盛, 孟龙, 邹俊杰, 黄小伟, 易沙沙. 头戴式超声神经刺激装置及系统. CN: CN111921101A, 2020-11-13.
[14] 郑海荣, 周慧, 牛丽丽, 孟龙, 夏向向, 庞娜. 超声聚焦控制方法、装置、电子设备及存储介质. CN: CN111863227A, 2020-10-30.
[15] 牛丽丽, 郑海荣, 易沙沙, 孟龙, 邹俊杰. 穿戴式超声刺激正中神经装置. CN: CN111659034A, 2020-09-15.
[16] 孟龙, 郑海荣, 王凯悦, 周伟, 牛丽丽, 黄小伟. 一种微流控芯片、装置、系统、控制及制备方法. CN: CN109985672B, 2020-07-24.
[17] 肖扬, 郑海荣, 王丛知, 牛丽丽, 邓志婷. 一种根据超声弹性肌动图获取生物力学参数的方法及装置. CN: CN107961038B, 2020-04-14.
[18] 郑海荣, 孟文, 牛丽丽, 孟龙. 超声调控及成像装置、方法、服务器及存储介质. CN: CN110882004A, 2020-03-17.
[19] 郑海荣, 黄小伟, 牛丽丽, 孟龙. 一种血脑屏障通透性调控装置、方法及存储介质. CN: CN110811690A, 2020-02-21.
[20] 郑海荣, 牛丽丽, 孟龙, 庞娜, 冯湘君. 一种头发再生装置及方法. CN: CN110801249A, 2020-02-18.
[21] 郑海荣, 牛丽丽, 王壹博, 孟龙, 肖杨, 边天元, 林争荣. 一种神经调控结果预测方法、装置及终端设备. CN: CN110647849A, 2020-01-03.
[22] 郑海荣, 黄小伟, 牛丽丽, 孟龙, 林争荣, 周伟, 边天元, 方佳朕. 一种超声刺激方法及装置. CN: CN110559564A, 2019-12-13.
[23] 郑海荣, 周慧, 牛丽丽, 孟龙, 夏向向, 邹俊杰. 一种超声治疗装置、方法及数据处理装置. CN: CN110478631A, 2019-11-22.
[24] 肖杨, 陈畅明, 牛丽丽, 王丛知, 马腾, 郑海荣. 一种癫痫发作检测装置、终端设备及存储介质. CN: CN110477865A, 2019-11-22.
[25] 肖杨, 陈畅明, 牛丽丽, 王丛知, 马腾, 郑海荣. 癫痫发作预测装置、终端设备以及计算机可读存储介质. CN: CN110477910A, 2019-11-22.
[26] 郑海荣, 黄小伟, 牛丽丽, 孟龙, 林争荣, 周伟. 脑内淋巴管刺激系统、方法及控制装置. CN: CN110477917A, 2019-11-22.
[27] 郑海荣, 周慧, 牛丽丽, 孟龙, 蔡飞燕, 夏向向. 一种神经调控装置及方法. CN: CN110368608A, 2019-10-25.
[28] 钱明, 牛丽丽, 郑海荣, 周伟. 一种全自动超声造影图像分割方法. CN: CN105631867B, 2019-08-23.
[29] 郑海荣, 周慧, 牛丽丽, 郭瑞彪, 孟龙, 李永川, 苏敏, 黄继卿, 钱明. 清醒动物超声神经调控装置. CN: CN106861061B, 2019-06-04.
[30] 郑海荣, 刘瑛喆, 袁狄飞, 牛丽丽, 林争荣, 徐礼胜, 齐林, 孟龙. 治疗成瘾性疾病的超声神经调控系统、方法及存储介质. CN: CN109718481A, 2019-05-07.
[31] 郑海荣, 黄小伟, 牛丽丽, 孟龙, 周伟, 钱明, 肖杨. 一种多阵元换能器的阵元选择装置、方法和超声刺激系统. CN: CN105999569B, 2019-03-12.
[32] 肖杨, 严飞, 郑海荣, 张雪, 邓志婷, 唐家伟, 牛丽丽. 一种用于HIFU的超声造影剂及其制备方法与应用. 中国: CN105233308B, 2018.10.30.
[33] 郑海荣, 林争荣, 牛丽丽, 孟龙, 周伟, 黄小伟, 王凯悦. 用于进行听觉恢复治疗的超声波的生成装置. 中国: CN108245314A, 2018.07.06.
[34] 郑海荣, 周慧, 牛丽丽, 孟龙, 夏向向, 张金钮, 郭瑞彪, 苏敏. 一种自动收线的超声神经调控装置. 中国: CN107551412A, 2018.01.09.
[35] 钱明, 郑海荣, 牛丽丽, 周伟. 一种超声三维流体成像与测速方法. 中国: CN105411624B, 2018-08-10.
[36] 郑海荣, 牛丽丽, 周伟, 钱明, 孟龙, 肖杨. 心脏功能评估方法和装置. 中国: CN104546012B, 2018-07-24.
[37] 郑海荣, 周伟, 孟龙, 牛丽丽, 林争荣, 王凯悦, 黄小伟. 微流控装置、将物质导入细胞的系统及方法. 中国: CN108239661A, 2018-07-03.
[38] 肖杨, 郑海荣, 王丛知, 牛丽丽, 李飞. 一种肌肉萎缩程度的检测方法、装置、设备及存储介质. 中国: CN108113709A, 2018-06-05.
[39] 郑海荣, 牛丽丽, 王丛知, 钱明, 肖杨, 孟龙. 一种获得用于发射穿颅聚焦超声的超声发射序列的方法及系统. 中国: CN104548390B, 2018-03-23.
[40] 郑海荣, 牛丽丽, 刘新, 孟龙, 邱维宝, 钱明, 蔡飞燕, 肖杨, 王丛知. 声敏感离子通道遗传操作方法及系统. 中国: CN106687587A, 2017-05-17.
[41] 肖杨, 郑海荣, 张雪, 王丛知, 牛丽丽. 一种基于超声弹性图像的病变区域提取方法及装置. 中国: CN105654490A, 2016-06-08.
[42] 郑海荣, 钱明, 李永川, 邱维宝, 牛丽丽, 王丛知. 一种基于大规模面阵元的超声脑刺激或调控方法及装置. 中国: CN105536156A, 2016-05-04.
[43] 郑海荣, 李飞, 蔡飞燕, 孟龙, 王辰, 张成祥, 邱维宝, 李永川, 严飞, 牛丽丽, 耿刘峰, 徐超伟. 基于人工结构声场的微流体系统及操控微粒的方法. 中国: CN105214742A, 2016-01-06.
[44] 郑海荣, 孟龙, 蔡飞燕, 牛丽丽, 李飞, 肖杨. 用于对特异性细胞进行筛选的微流控芯片及细胞筛选方法. 中国: CN104195028A, 2014.12.10.
[45] 郑海荣, 孟龙, 蔡飞燕, 牛丽丽, 李飞, 肖杨. 基因导入芯片及基因导入方法. 中国: CN103981090A, 2014.08.13.
[46] 肖杨, 张雪, 郑海荣, 牛丽丽, 王丛知. 病变组织生长监测方法和系统. 中国: CN103720489A, 2014-04-16.
[47] 肖杨, 郑海荣, 张雪, 牛丽丽, 王丛知. 基于宽带信号的血流流速估计方法和系统. 中国: CN103690194A, 2014-04-02.
[48] 郑海荣, 牛丽丽, 钱明, 孟龙, 肖杨, 王丛知. 一种管壁应力相位角的测量方法和系统. 中国: CN103340620A, 2013-10-09.
[49] 王丛知, 郑海荣, 钱明, 肖杨, 李永川, 牛丽丽. 无创连续血压测量装置与方法. 中国: CN103110431A, 2013-05-22.
[50] 郑海荣, 牛丽丽, 钱明, 孙风雷, 肖扬, 王丛知. 血管壁病变检测方法. 中国: CN103054563A, 2013-04-24.
[51] 钱明, 郑海荣, 李永川, 王丛知, 肖杨, 牛丽丽. 超声换能器. 中国: CN202802550U, 2013-03-20.
[52] 郑海荣, 牛丽丽, 钱明. 基于图像的生物组织弹性的测量方法及装置. 中国: CN102423264A, 2012-04-25.
[53] 郑海荣, 龚小竞, 牛丽丽, 金雷, 张元亭. 同时获取生物组织的结构和成分信息的装置及方法. 中国: CN101451942, 2009-06-10.

出版信息

发表论文

[1] Huang, Xiaowei, Niu, Lili, Meng, Long, Lin, Zhengrong, Zhou, Wei, Liu, Xiufang, Huang, Jiqing, Abbott, Derek, Zheng, Hairong. Transcranial Low-Intensity Pulsed Ultrasound Stimulation Induces Neuronal Autophagy. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2021, 68(1): 46-53, https://www.webofscience.com/wos/woscc/full-record/WOS:000602706700005.
[2] Lin, Zhengrong, Bian, Tianyuan, Zhou, Wei, Wang, Yibo, Huang, Xiaowei, Zou, Junjie, Zhou, Hui, Niu, Lili, Tang, Jie, Meng, Long. Modulation of Neuronal Excitability by Low-Intensity Ultrasound in Two Principal Neurons of Rat Anteroventral Cochlear Nucleus. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2021, 68(5): 1752-1761, http://dx.doi.org/10.1109/TUFFC.2021.3052203.
[3] Wang, Yibo, Niu, Lili, Meng, Wen, Lin, Zhengrong, Zou, Junjie, Bian, Tianyuan, Huang, Xiaowei, Zhou, Hui, Meng, Long, Xie, Ping, Zheng, Hairong. Ultrasound Stimulation of Periaqueductal Gray Induces Defensive Behaviors. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2021, 68(1): 38-45, https://www.webofscience.com/wos/woscc/full-record/WOS:000602706700004.
[4] Pang, Na, Huang, Xiaowei, Zhou, Hui, Xia, Xiangxiang, Liu, Xiufang, Wang, Yibo, Meng, Wen, Bian, Tianyuan, Meng, Long, Xu, Lisheng, Niu, Lili. Transcranial Ultrasound Stimulation of Hypothalamus in Aging Mice. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2021, 68(1): 29-37, https://www.webofscience.com/wos/woscc/full-record/WOS:000603483500001.
[5] Zhang, Jinniu, Zhou, Hui, Yang, Jian, Jia, Jun, Niu, Lili, Sun, Zuoli, Shi, Dandan, Meng, Long, Qiu, Weibao, Wang, Xiaomin, Zheng, Hairong, Wang, Gang. Low-intensity pulsed ultrasound ameliorates depression-like behaviors in a rat model of chronic unpredictable stress. CNS NEUROSCIENCE & THERAPEUTICS[J]. 2021, 27(2): 233-243, https://www.webofscience.com/wos/woscc/full-record/WOS:000584911200001.
[6] Zhou, Hui, Meng, Long, Xia, Xiangxiang, Lin, Zhengrong, Zhou, Wei, Pang, Na, Bian, Tianyuan, Yuan, Tifei, Niu, Lili, Zheng, Hairong. Transcranial Ultrasound Stimulation Suppresses Neuroinflammation in a Chronic Mouse Model of Parkinson's Disease. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2021, 68(11): 3375-3387, [7] Xiaofei Qi, Kexin Lyu, Long Meng, Cuixian Li, Hongzheng Zhang, Lili Niu, Zhengrong Lin, Hairong Zheng, Jie Tang. Low-Intensity Ultrasound Causes Direct Excitation of Auditory Cortical Neurons. NEURAL PLASTICITY[J]. 2021, 2021: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8041518/.
[8] Zou, Junjie, Meng, Long, Lin, Zhengrong, Qiao, Yangzi, Tie, Changjun, Wang, Yibo, Huang, Xiaowei, Yuan, Tifei, Chi, Yajie, Meng, Wen, Niu, Lili, Guo, Yanwu, Zheng, Hairong. Ultrasound Neuromodulation Inhibits Seizures in Acute Epileptic Monkeys. ISCIENCE[J]. 2020, 23(5): http://dx.doi.org/10.1016/j.isci.2020.101066.
[9] 郑海荣, 邱维宝, 王丛知, 牛丽丽, 严飞, 蔡飞燕, 邹超, 隆晓菁, 乔阳紫, 肖杨. 超声成像与治疗技术进展与趋势. 中国科学:生命科学[J]. 2020, 50(11): 1256-1267, http://lib.cqvip.com/Qikan/Article/Detail?id=7103245117.
[10] Meng, Long, Cui, Xiaoyu, Dong, Chenyu, Liu, Xiufang, Zhou, Wei, Zhang, Wenjun, Wang, Xinhui, Niu, Lili, Li, Fei, Cai, Feiyan, Wu, Junru, Zheng, Hairong. Microbubble enhanced acoustic tweezers for size-independent cell sorting. APPLIED PHYSICS LETTERS[J]. 2020, 116(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000519603100001.
[11] 易沙沙, 邹俊杰, 冯相君, 刘秀芳, 马寅仲, 畅君雷, 孟龙, 敖丽娟, 牛丽丽. 低强度聚焦超声对缺血性脑卒中的干预作用. 中华超声影像学杂志. 2020, 29(12): 1089-1094, http://lib.cqvip.com/Qikan/Article/Detail?id=7104152361.
[12] Lin, Zhengrong, Meng, Long, Zou, Junjie, Zhou, Wei, Huang, Xiaowei, Xue, Shan, Bian, Tianyuan, Yuan, Tifei, Niu, Lili, Guo, Yanwu, Zheng, Hairong. Non-invasive ultrasonic neuromodulation of neuronal excitability for treatment of epilepsy. THERANOSTICS[J]. 2020, 10(12): 5514-5526, https://www.webofscience.com/wos/woscc/full-record/WOS:000526083000021.
[13] Niu, Lili, Guo, Yanchen, Lin, Zhengrong, Shi, Zhe, Bian, Tianyuan, Qi, Lin, Meng, Long, Grace, Anthony A, Zheng, Hairong, Yuan, TiFei. Noninvasive ultrasound deep brain stimulation of nucleus accumbens induces behavioral avoidance. SCIENCE CHINA-LIFE SCIENCES[J]. 2020, 63(9): 1328-1336, http://lib.cqvip.com/Qikan/Article/Detail?id=7102701593.
[14] 郑海荣, 牛丽丽, 王丛知, 李飞. 超声力学效应在医学诊疗中的创新与转化. 生物医学转化. 2020, 1(1): 8-17, http://lib.cqvip.com/Qikan/Article/Detail?id=7103692879.
[15] Xu, Lisheng, Zhang, Yanling, Meng, Long, Li, Shuai, Niu, Lili, Greenwald, Stephen E, Zhang, Hui, Wang, Lu. Ultrasound Assessment of the Relation Between Local Hemodynamic Parameters and Plaque Morphology. IEEE ACCESS[J]. 2020, 8: 145149-145158, https://doaj.org/article/5a971fdf1fa847a18c15b33efa2da7d4.
[16] Jin, Yao, Li, Yongchuan, Ye, Yang, Zou, Junjie, Guo, Tianxu, Bian, Tianyuan, Wang, Congzhi, Xiao, Yang, Niu, Lili, Ma, Teng, Zheng, Hairong. Development of Multi-Layer Lateral-Mode Ultrasound Needle Transducer for Brain Stimulation in Mice. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2020, 67(7): 1982-1988, https://www.webofscience.com/wos/woscc/full-record/WOS:000544063000016.
[17] Liu, Xiufang, Li, Jinyuan, Zhang, Liangyu, Huang, Xiaowei, Farooq, Umar, Pang, Na, Zhou, Wei, Qi, Lin, Xu, Lisheng, Niu, Lili, Meng, Long. Cell Lysis Based on an Oscillating Microbubble Array. MICROMACHINES[J]. 2020, 11(3): https://www.webofscience.com/wos/woscc/full-record/WOS:000526546000033.
[18] Kang, Hongyu, Zhang, Yanling, Huang, Xiaowei, Niu, Lili, Zhang, Hui, Xu, Lisheng, Abbott, Derek. Quantification of Atherosclerotic Plaque Elasticity Using Ultrasonic Texture Matching. IEEE ACCESS[J]. 2020, 8: 94268-94278, https://doaj.org/article/51f47a7723204dd7a9321d4a763f66bf.
[19] Huang, Xiaowei, Lin, Zhengrong, Wang, Kaiyue, Liu, Xiufang, Zhou, Wei, Meng, Long, Huang, Jiqing, Yuan, Kexin, Niu, Lili, Zheng, Hairong. Transcranial Low-Intensity Pulsed Ultrasound Modulates Structural and Functional Synaptic Plasticity in Rat Hippocampus. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2019, 66(5): 930-938, https://www.webofscience.com/wos/woscc/full-record/WOS:000466195200011.
[20] Zhou, Hui, Niu, Lili, Xia, Xiangxiang, Lin, Zhengrong, Liu, Xiufang, Su, Min, Guo, Ruibiao, Meng, Long, Zheng, Hairong. Wearable Ultrasound Improves Motor Function in an MPTP Mouse Model of Parkinson's Disease. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2019, 66(11): 3006-3013, https://www.webofscience.com/wos/woscc/full-record/WOS:000502102200002.
[21] Zhou, Wei, Chen, Mian, Liu, Xiufang, Zhang, Wenjun, Cai, Feiyan, Li, Fei, Wu, Junru, Wang, Jinping, Wang, Yang, Huang, Xiaowei, Lin, Zhengrong, Zhou, Hui, Meng, Long, Niu, Lili, Zheng, Hairong. Selective photothermal ablation of cancer cells by patterned gold nanocages using surface acoustic waves. LAB ON A CHIP[J]. 2019, 19(20): 3387-3396, https://www.webofscience.com/wos/woscc/full-record/WOS:000490548200017.
[22] Meng, Long, Liu, Xiufang, Wang, Yuchen, Zhang, Wenjun, Zhou, Wei, Cai, Feiyan, Li, Fei, Wu, Junru, Xu, Lisheng, Niu, Lili, Zheng, Hairong. Sonoporation of Cells by a Parallel Stable Cavitation Microbubble Array. Advanced Science[J]. 2019, 6(17): n/a-n/a, https://doaj.org/article/4ef857a8769141a196bf021d1747f3eb.
[23] Huang, Xiaowei, Lin, Zhengrong, Meng, Long, Wang, Kaiyue, Liu, Xiufang, Zhou, Wei, Zheng, Hairong, Niu, Lili. NON-INVASIVE LOW-INTENSITY PULSED ULTRASOUND MODULATES PRIMARY CILIA OF RAT HIPPOCAMPAL NEURONS. ULTRASOUND IN MEDICINE AND BIOLOGY[J]. 2019, 45(5): 1274-1283, http://dx.doi.org/10.1016/j.ultrasmedbio.2018.12.012.
[24] Zhou, Hui, Niu, Lili, Meng, Long, Lin, Zhengrong, Zou, Junjie, Xia, Xiangxiang, Huang, Xiaowei, Zhou, Wei, Bian, Tianyuan, Zheng, Hairong. Noninvasive Ultrasound Deep Brain Stimulation for the Treatment of Parkinson's Disease Model Mouse. RESEARCH[J]. 2019, 2019(4): http://dx.doi.org/10.34133/2019/1748489.
[25] 邹俊杰, 林争荣, 牛丽丽, 郭燕舞. 聚焦超声在癫痫等中枢神经系统疾病治疗中的应用及机制. 中华神经医学杂志[J]. 2018, 17(2): 212-216, http://lib.cqvip.com/Qikan/Article/Detail?id=674660308.
[26] Zhang, Bo, Gu, Junyi, Qian, Ming, Niu, Lili, Ghista, Dhanjoo. Study of correlation between wall shear stress and elasticity in atherosclerotic carotid arteries. BIOMEDICAL ENGINEERING ONLINE[J]. 2018, 17(1): http://ir.siat.ac.cn:8080/handle/172644/14306.
[27] Huang, Xiaowei, Zhang, Yanling, Meng, Long, Qian, Ming, Wong, Kelvin Kian Loong, Abbott, Derek, Zheng, Rongqin, Zheng, Hairong, Niu, Lili. Identification of Ultrasonic Echolucent Carotid Plaques Using Discrete Frechet Distance Between Bimodal Gamma Distributions. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2018, 65(5): 949-955, http://ir.siat.ac.cn:8080/handle/172644/14328.
[28] Niu, Lili, Zhu, Xiliang, Pan, Min, Derek, Abbott, Xu, Lisheng, Meng, Long, Zheng, Hairong. Influence of vascular geometry on local hemodynamic parameters: phantom and small rodent study. BIOMEDICAL ENGINEERING ONLINE[J]. 2018, 17(1): http://ir.siat.ac.cn:8080/handle/172644/14320.
[29] Niu Lili. Identification of Ultrasonic Echolucent Carotid Plaques Using Discrete Fréchet Distance Between Bimodal Gamma Distributions. IEEE Transactions on Biomedical Engineering. 2018, [30] 赵章风, 张文俊, 牛丽丽, 孟龙, 郑海荣. 基于微泡共振的快速微流体声学混合方法研究. 物理学报[J]. 2018, 67(19): 194302-1, http://lib.cqvip.com/Qikan/Article/Detail?id=676473832.
[31] Lin, Zhengrong, Zhou, Wei, Huang, Xiaowei, Wang, Kaiyue, Tang, Jie, Niu, Lili, Meng, Long, Zheng, Hairong. On-Chip Ultrasound Modulation of Pyramidal Neuronal Activity in Hippocampal Slices. ADVANCED BIOSYSTEMS[J]. 2018, 2(8): http://ir.siat.ac.cn:8080/handle/172644/14381.
[32] Wang, Kaiyue, Zhou, Wei, Lin, Zhengrong, Cai, Feiyan, Li, Fei, Wu, Junru, Meng, Long, Niu, Lili, Zheng, Hairong. Sorting of tumour cells in a microfluidic device by multi-stage surface acoustic waves. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2018, 258: 1174-1183, http://ir.siat.ac.cn:8080/handle/172644/14317.
[33] Kaiyue Wang, Wei Zhou, Zhengrong Lin, Feiyan Cai, Fei Li, Junru Wu, Long Meng, Lili Niu, Hairong Zheng. Sorting of tumour cells in a microfluidic device by multi-stage surface acoustic waves. Sensors & Actuators: B. Chemical. 2018, 258: 1174-1183, http://dx.doi.org/10.1016/j.snb.2017.12.013.
[34] Li, Fei, Yan, Fei, Chen, Zhiyi, Lei, Junjun, Yu, Jinsui, Chen, Mian, Zhou, Wei, Meng, Long, Niu, Lili, Wu, Junru, Li, Jiangyu, Cai, Feiyan, Zheng, Hairong. Phononic crystal-enhanced near-boundary streaming for sonoporation. APPLIED PHYSICS LETTERS[J]. 2018, 113(8): http://ir.siat.ac.cn:8080/handle/172644/14348.
[35] Zhao ZhangFeng, Zhang WenJun, Niu LiLi, Meng Long, Zheng HaiRong. Microbubble oscillation induced acoustic micromixing in microfluidic device. ACTA PHYSICA SINICA[J]. 2018, 67(19): https://www.webofscience.com/wos/woscc/full-record/WOS:000448517700015.
[36] Huang, Xiaowei, Zhang, Yanling, Meng, Long, Abbott, Derek, Qian, Ming, Wong, Kelvin K L, Zheng, Rongqing, Zheng, Hairong, Niu, Lili. Evaluation of carotid plaque echogenicity based on the integral of the cumulative probability distribution using gray-scale ultrasound images. PLOS ONE[J]. 2017, 12(10): http://dx.doi.org/10.1371/journal.pone.0185261.
[37] Zhang, Bo, Gu, Junyi, Qian, Ming, Niu, Lili, Zhou, Hui, Ghista, Dhanjoo. Correlation between quantitative analysis of wall shear stress and intima-media thickness in atherosclerosis development in carotid arteries. BIOMEDICAL ENGINEERING ONLINE[J]. 2017, 16(1): https://doaj.org/article/9e15162f12e54c88be1b198fcb27861c.
[38] Xiao, Yang, Zeng, Jie, Zhang, Xue, Niu, LiLi, Qian, Ming, Wang, CongZhi, Zheng, HaiRong, Zheng, RongQin. Ultrasound Strain Elastography for Breast Lesions Computer-Aided Evaluation With Quantifiable Elastographic Features. JOURNAL OF ULTRASOUND IN MEDICINE[J]. 2017, 36(6): 1089-1100, https://www.webofscience.com/wos/woscc/full-record/WOS:000401914600002.
[39] Zhou, Wei, Wang, Jingjing, Wang, Kaiyue, Huang, Bin, Niu, Lili, Li, Fei, Cai, Feiyan, Chen, Yan, Liu, Xin, Zhang, Xiaoyan, Cheng, Hankui, Kang, Lijun, Meng, Long, Zheng, Hairong. Ultrasound neuro-modulation chip: activation of sensory neurons in Caenorhabditis elegans by surface acoustic waves. LAB ON A CHIP[J]. 2017, 17(10): 1725-1731, https://www.webofscience.com/wos/woscc/full-record/WOS:000401551300003.
[40] Niu, Lili, Zhang, Yanling, Qian, Ming, Xiao, Yang, Meng, Long, Zheng, Rongqin, Zheng, Hairong. Standard deviation of carotid young's modulus and presence or absence of plaque improves prediction of coronary heart disease risk. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING[J]. 2017, 37(6): 682-687, http://www.chinair.org.cn/handle/1471x/1747551.
[41] Zhou, Hui, Meng, Long, Zhou, Wei, Xin, Lin, Xia, Xiangxiang, Li, Shuai, Zheng, Hairong, Niu, Lili. Computational and experimental assessment of influences of hemodynamic shear stress on carotid plaque. BIOMEDICAL ENGINEERING ONLINE[J]. 2017, 16(1): https://doaj.org/article/2dd6b54dc48e4b12a7e828ed90109d4b.
[42] Huang, XiaoWei, Zhang, YanLing, Meng, Long, Qian, Ming, Zhou, Wei, Zheng, RongQin, Zheng, HaiRong, Niu, LiLi. The relationship between HbA(1c) and ultrasound plaque textures in atherosclerotic patients. CARDIOVASCULAR DIABETOLOGY[J]. 2016, 15(1): http://dx.doi.org/10.1186/s12933-016-0422-5.
[43] 张耀楠, 周伟, 牛丽丽. 超声粒子图像测速技术评估左心室涡旋特性的初步研究. 中国医疗设备. 2016, 36-41, http://lib.cqvip.com/Qikan/Article/Detail?id=669323219.
[44] 李帅, 牛丽丽, 钱明, 徐礼胜, 郑海荣. 不同狭窄度斑块的血流动力参数检测方法研究. 集成技术[J]. 2016, 81-87, http://lib.cqvip.com/Qikan/Article/Detail?id=669659760.
[45] Niu Lili. Classification of carotid plaque echogenicity by combining texture features and morphological characteristics. Journal of Ultrasound in Medicine. 2016, [46] Zhou, Wei, Niu, Lili, Cai, Feiyan, Li, Fei, Wang, Chen, Huang, Xiaowei, Wang, Jingjing, Wu, Junru, Meng, Long, Zheng, Hairong. Spatial selective manipulation of microbubbles by tunable surface acoustic waves. BIOMICROFLUIDICS[J]. 2016, 10(3): [47] Zhang Yanling, Huang, Xiaowei, Niu, Lili, Zhong, Junlin, Zheng, Hairong, Zheng, Rongqin. A non-invasive method for identifying type 2 diabetes based on carotid ultrasound plaque textures. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYnull. 2016, 68(16): C124-C124, [48] Li, GuoFeng, Zhao, HuiXia, Zhou, Hui, Yan, Fei, Wang, JingYao, Xu, ChangXi, Wang, CongZhi, Niu, LiLi, Meng, Long, Wu, Song, Zhang, HuaiLing, Qiu, WeiBao, Zheng, HaiRong. Improved Anatomical Specificity of Non-invasive Neuro-stimulation by High Frequency (5 MHz) Ultrasound. SCIENTIFIC REPORTS[J]. 2016, 6: https://www.webofscience.com/wos/woscc/full-record/WOS:000374381800001.
[49] Huang, Xiaowei, Zhang, Yanling, Qian, Ming, Meng, Long, Xiao, Yang, Niu, Lili, Zheng, Rongqin, Zheng, Hairong. Classification of Carotid Plaque Echogenicity by Combining Texture Features and Morphologic Characteristics. JOURNAL OF ULTRASOUND IN MEDICINE[J]. 2016, 35(10): 2253-2261, http://dx.doi.org/10.7863/ultra.15.09002.
[50] Zhang Yanling, Zhong, Junlin, Niu, Lili, Zhang, Hui, Zheng, Hairong, Zheng, Rongqin. Non-invasive evaluation of carotid IMT, elasticity and presence or absence of plaque predicts of carotid heart disease risk. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYnull. 2016, 68(16): C124-C124, https://www.webofscience.com/wos/woscc/full-record/WOS:000397301500455.
[51] Niu, Lili, Meng, Long, Xu, Lisheng, Liu, Jia, Wang, Qiwen, Xiao, Yang, Qian, Ming, Zheng, Hairong. Stress phase angle depicts differences in arterial stiffness: phantom and in vivo study. PHYSICS IN MEDICINE AND BIOLOGY[J]. 2015, 60(11): 4281-4294, https://www.webofscience.com/wos/woscc/full-record/WOS:000355210600006.
[52] Su Min, Xue Shu, Li Yongchuan, Niu Lili, Xiao Yang, Wang C Z, Qiu Weibao, Zheng Hairong, Qian Ming, IEEE. Design and fabrication of a novel three-row dual frequency ultrasound transducer for image-guided drug delivery. 2015 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS)null. 2015, [53] 黄小伟, 张艳玲, 牛丽丽, 郑海荣, 钱明, 郑荣琴, 卢广文. MaZda评估动脉粥样硬化斑块的风险性. 中国医学影像技术[J]. 2015, 31(1): 141-145, [54] 郑海荣, 蔡飞燕, 严飞, 牛丽丽, 李飞, 孟龙, 邱维宝. 多功能生物医学超声：分子影像、给药与神经调控. 科学通报[J]. 2015, 60(20): 1864-1873, [55] Huang, Zhigang, Li, Yuebing, Niu, Lili, Xiao, Yang, Pu, Xiaodong, Zheng, Hairong, Qian, Ming. Dynamic expressions of monocyte chemo attractant protein-1 and CC chamomile receptor 2 after balloon injury and their effects in intimal proliferation. BIOMEDICAL ENGINEERING ONLINE[J]. 2015, 14(1): https://www.webofscience.com/wos/woscc/full-record/WOS:000359826900001.
[56] Meng Long, Deng Zhiting, Niu Lili, Cai Feiyan, Zheng Hairong, IEEE. Controlled Thermal-Sensitive Liposomes Release on a Disposable Microfluidic Device. 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)null. 2015, 5912-5915, [57] Zhang, Yanling, Niu, Lili, Zhong, Junlin, Zheng, Hairong, Zheng, Rongqin. Prediction of Coronary Heart Disease Using the Standard Deviation of Carotid Young's Modulus and Presence or Absence of Plaque. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYnull. 2015, 66(16): C261-C261, https://www.webofscience.com/wos/woscc/full-record/WOS:000366310300450.
[58] Meng, Long, Deng, Zhiting, Niu, Lili, Li, Fei, Yan, Fei, Wu, Junru, Cai, Feiyan, Zheng, Hairong. A Disposable Microfluidic Device for Controlled Drug Release from Thermal-Sensitive Liposomes by High Intensity Focused Ultrasound. THERANOSTICS[J]. 2015, 5(11): 1203-1213, https://www.webofscience.com/wos/woscc/full-record/WOS:000360297600003.
[59] Zhang Yanling, Niu Lili, Zheng Hairong, Liu Jinlai, Zhang Hui, Xu Shicheng, Zheng Rongqin. GW25-e4220 Comparison of two methods for evaluating human carotid artery elasticity: Possible detection of early atherosclerosis In subjects with dyslipidemia. Journal of the American College of Cardiology. 2014, 64(16): C232-C233, http://dx.doi.org/10.1016/j.jacc.2014.06.1083.
[60] Meng, Long, Cai, Feiyan, Jiang, Peng, Deng, Zhiting, Li, Fei, Niu, Lili, Chen, Yan, Wu, Junru, Zheng, Hairong. On-chip targeted single cell sonoporation with microbubble destruction excited by surface acoustic waves. APPLIED PHYSICS LETTERS[J]. 2014, 104(7): https://www.webofscience.com/wos/woscc/full-record/WOS:000332038500083.
[61] 朱懿恒, 钱明, 牛丽丽, 郑海荣, 卢广文. 基于超声粒子成像技术的大鼠动脉模型血流剪切力测量方法. 生物医学工程学杂志[J]. 2014, 31(6): 1355-1360, [62] Xiao, Yang, Zeng, Jie, Niu, Lili, Zeng, Qingjing, Wu, Tao, Wang, Congzhi, Zheng, Rongqin, Zheng, Hairong. COMPUTER-AIDED DIAGNOSIS BASED ON QUANTITATIVE ELASTOGRAPHIC FEATURES WITH SUPERSONIC SHEAR WAVE IMAGING. ULTRASOUND IN MEDICINE AND BIOLOGY[J]. 2014, 40(2): 275-286, http://dx.doi.org/10.1016/j.ultrasmedbio.2013.09.032.
[63] Niu, Lili, Zhang, Yanling, Meng, Long, Xiao, Yang, Wong, Kelvin K L, Abbott, Derek, Zheng, Hairong, Zheng, Rongqin, Qian, Ming. Detection of Subclinical Atherosclerosis in Asymptomatic Subjects Using Ultrasound Radiofrequency-Tracking Technology. PLOS ONE[J]. 2014, 9(11): https://doaj.org/article/7a285b9c955542ab8eced5ad1f16ec0d.
[64] Zhang Yanling, Niu Lili, Zheng Hairong, Liu Jinlai, Zhang Hui, Xu Shicheng, Zheng Rongqin. Comparison of two methods for evaluating human carotid artery elasticity: Possible detection of early atherosclerosis In subjects with dyslipidemia. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGYnull. 2014, 64(16): C232-C233, https://www.webofscience.com/wos/woscc/full-record/WOS:000362727300476.
[65] Qian, Ming, Niu, Lili, Wong, Kelvin Kian Loong, Abbott, Derek, Zhou, Qifa, Zheng, Hairong. Pulsatile Flow Characterization in a Vessel Phantom With Elastic Wall Using Ultrasonic Particle Image Velocimetry Technique: The Impact of Vessel Stiffness on Flow Dynamics. IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING[J]. 2014, 61(9): 2444-2450, https://www.webofscience.com/wos/woscc/full-record/WOS:000346226100009.
[66] Niu, Lili, Qian, Ming, Yang, Wei, Meng, Long, Xiao, Yang, Wong, Kelvin K L, Abbott, Derek, Liu, Xin, Zheng, Hairong. Surface Roughness Detection of Arteries via Texture Analysis of Ultrasound Images for Early Diagnosis of Atherosclerosis. PLOS ONE[J]. 2013, 8(10): https://doaj.org/article/d4526d582d624549ae2642bfe488d45e.
[67] 牛丽丽. 超声生物力学成像方法研究及应用. 2013, [68] Niu, Lili, Zhang, Yanling, Qian, Ming, Meng, Long, Xiao, Yang, Wang, Yuanyuan, Liu, Xin, Zheng, Rongqin, Zheng, Hairong. Impact of Multiple Cardiovascular Risk Factors on Carotid Intima-Media Thickness and Elasticity. PLOS ONE[J]. 2013, 8(7): https://doaj.org/article/4314ca3a043b4e0faf7311bdc361acb4.
[69] Xiao, Yang, Shen, Yang, Niu, Lili, Ling, Tao, Wang, Congzhi, Zheng, Hairong. Strain Estimation in Elastography Using Scale-Invariant Keypoints Tracking. IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL[J]. 2013, 60(4): 706-717, https://www.webofscience.com/wos/woscc/full-record/WOS:000317010200007.
[70] Niu, Lili, Qian, Ming, Song, Ruibo, Meng, Long, Liu, Xin, Zheng, Hairong. A TEXTURE MATCHING METHOD CONSIDERING GEOMETRIC TRANSFORMATIONS IN NONINVASIVE ULTRASONIC MEASUREMENT OF ARTERIAL ELASTICITY. ULTRASOUND IN MEDICINE AND BIOLOGY[J]. 2012, 38(3): 524-533, http://dx.doi.org/10.1016/j.ultrasmedbio.2011.12.010.
[71] Niu, Lili, Qian, Ming, Song, Ruibo, Meng, Long, Liu, Xin, Zheng, Hairong. A 2D non-invasive ultrasonic method for simultaneous measurement of arterial strain and flow pattern. CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING[J]. 2012, 32(4): 323-329, http://dx.doi.org/10.1111/j.1475-097X.2012.01130.x.
[72] Lili Niu, Ming Qian, Ruibo Song, Long Meng, Xin Liu, Hairong Zheng. A Texture Matching Method Considering Geometric Transformations in Noninvasive Ultrasonic Measurement of Arterial Elasticity. Ultrasound in Medicine & Biology. 2012, 38(3): 524-533, http://dx.doi.org/10.1016/j.ultrasmedbio.2011.12.010.
[73] Niu, Lili, Qian, Ming, Yan, Liang, Yu, Wentao, Jiang, Bo, Jin, Qiaofeng, Wang, Yanping, Shandas, Robin, Liu, Xin, Zheng, Hairong. REAL-TIME TEXTURE ANALYSIS FOR IDENTIFYING OPTIMUM MICROBUBBLE CONCENTRATION IN 2-D ULTRASONIC PARTICLE IMAGE VELOCIMETRY. ULTRASOUND IN MEDICINE AND BIOLOGY[J]. 2011, 37(8): 1280-1291, http://dx.doi.org/10.1016/j.ultrasmedbio.2011.05.006.
[74] Meng, Long, Cai, Feiyan, Jin, Qiaofeng, Niu, Lili, Jiang, Chunxiang, Wang, Zhanhui, Wu, Junru, Zheng, Hairong. Acoustic aligning and trapping of microbubbles in an enclosed PDMS microfluidic device. SENSORS AND ACTUATORS B-CHEMICAL[J]. 2011, 160(1): 1599-1605, http://dx.doi.org/10.1016/j.snb.2011.10.015.
[75] ZHENG Hairong, QIAN Ming, LING Tao, JIN Qiaofeng, NIU lili. Echo particle image velocimetry technique and its applications. 声学学报：英文版. 2011, 30(2): 162-170, http://lib.cqvip.com/Qikan/Article/Detail?id=37191019.
[76] Jin Qiaofeng, Qian Ming, Niu Lili, Zheng Hairong, IEEE. Preparation of microbubbles for high frequency ultrasound and their application in rat and rabbit. 2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010)null. 2010, [77] Qian Ming, Yan Liang, Niu Lili, Jin Qiaofeng, Yu Wentao, Zheng Hairong, IEEE. Noninvasive characterization of velocity profiles and shear rates within microcirculation system using a novel micro-ultrasound imaging technique. 2010 4TH INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICAL ENGINEERING (ICBBE 2010)null. 2010, [78] Niu, Lili, Qian, Ming, Wan, Kun, Yu, Wentao, Jin, Qiaofeng, Ling, Tao, Gao, Shen, Zheng, Hairong. Ultrasonic particle image velocimetry for improved flow gradient imaging: algorithms, methodology and validation. PHYSICS IN MEDICINE AND BIOLOGY[J]. 2010, 55(7): 2103-2120, http://dx.doi.org/10.1088/0031-9155/55/7/020.
[79] 郑海荣, 钱明, 凌涛, 靳巧峰, 牛丽丽. 超声粒子图像测速技术及应用. 声学学报[J]. 2009, 548-553, http://lib.cqvip.com/Qikan/Article/Detail?id=32321682.
[80] Benacerraf Beryl R. Journal of Ultrasound in Medicine in the New Millennium. Journal of Ultrasound in Medicine[J]. http://dx.doi.org/10.7863/jum.2002.21.1.1.

科研活动

科研项目

（ 1 ）基于超声生物力学成像方法的血管斑块力学特性研究, 主持, 国家级, 2016-01--2019-12
（ 2 ）血管壁周向应力和血流剪切应力相位角的高分辨超声实验研究, 主持, 国家级, 2014-01--2016-12
（ 3 ）超声无创心血管疾病早期检测技术, 主持, 省级, 2013-10--2015-10
（ 4 ）血管早期病变超声无创检测方法研究, 主持, 省级, 2016-01--2017-12