类生命自组装体系的构筑以及其在生物医药、智能材料、催化等领域中的应用

   

0703Z1-化学生物学
085600-材料与化工
086000-生物与医药

生物分子组装功能系统
智能药物与精准治疗
非平衡活性材料

2012-09--2017-07   中国科学院过程工程研究所   博士
2008-09--2012-07   燕山大学   学士

   

2023-05~现在, 中国科学院深圳先进技术研究院, 研究员
2018-06~2023-02,荷兰格罗宁根大学, 博士后

   

（1） 中国科学院优秀博士论文, 院级, 2018
（2） 中国科学院院长奖, 院级, 2017
（3） 过程工程研究所所长特别奖学金, 研究所（学校）, 2017
（4） 过程工程研究所所长奖学金, 研究所（学校）, 2016
（5） 宝钢优秀学生奖, 院级, 2016
（6） 朱李月华奖学金, 院级, 2016
（7） 国家奖学金, 国家级, 2016

（ 1 ） 一种光敏剂纳米粒及其制备方法和用途, 专利授权, 2015, 第 3 作者, 专利号: CN104984340A

   

（1） Light-Driven Ecological-Evolutionary Dynamics in a Synthetic Replicator System, Nature Chemistry (accepted), 2023, 第 1 作者
（2） Systems Chemistry across Multiple Length Scales: Macroscopic Flow via Dissipative Co-Assemblies Featuring Transient Amides, Chemrxiv, 2022, 第 1 作者
（3） Out-of-Equilibrium Self-Replication Allows Selection for Dynamic Kinetic Stability in a System of Competing Replicators, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2022, 第 6 作者
（4） Vitamin C supramolecular hydrogel for enhanced cancer immunotherapy, BIOMATERIALS, 2022, 第 2 作者
（5） Self-Sorting in Dynamic Combinatorial Libraries Leads to the Co-Existence of Foldamers and Self-Replicators, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 4 作者
（6） Chemical Fueling Enables Molecular Complexification of Self-Replicators**, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 第 5 作者
（7） Emergence of low-symmetry foldamers from single monomers, NATURE CHEMISTRY, 2020, 第 10 作者
（8） Emergence of light-driven protometabolism on recruitment of a photocatalytic cofactor by a self-replicator, NATURE CHEMISTRY, 2020, 第 2 作者
（9） Photooxidase-mimicking nanovesicles with superior photocatalytic activity and stability based on amphiphilic amino acid and phthalocyanine co-assembly, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2019, 第 2 作者
（10） Peptide-Directed Hierarchical Mineralized Silver Nanocages for Anti-Tumor Photothermal Therapy, ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2018, 第 3 作者
（11） Amino-Acid-Mediated Biomimetic Formation of Light-Harvesting Antenna Capable of Hydrogen Evolution, ACS APPLIED BIO MATERIALS, 2018, 第 2 作者
（12） Primitive Photosynthetic Architectures Based on Self-Organization and Chemical Evolution of Amino Acids and Metal Ions, ADVANCED SCIENCE, 2018, 第 1 作者
（13） Self-Assembled Minimalist Multifunctional Theranostic Nanoplatform for Magnetic Resonance Imaging-Guided Tumor Photodynamic Therapy, ACS NANO, 2018, 第 2 作者
（14） Tunable Aggregation-Induced Emission of Tetraphenylethylene via Short Peptide-Directed Self-Assembly, ADVANCED MATERIALS INTERFACES, 2017, 第 1 作者
（15） Self-assembly of biomimetic light-harvesting complexes capable of hydrogen evolution, GREEN ENERGY & ENVIRONMENT, 2017, 第 1 作者
（16） Enzyme-immobilized clay nanotube-chitosan membranes with sustainable biocatalytic activities, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2017, 第 3 作者
（17） Self-Assembled Zinc/Cystine-Based Chloroplast Mimics Capable of Photoenzymatic Reactions for Sustainable Fuel Synthesis, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2017, 第 1 作者
（18） Biomimetic Oxygen-Evolving Photobacteria Based on Amino Acid and Porphyrin Hierarchical Self-Organization, ACS NANO, 2017, 第 1 作者
（19） Castor oil-based waterborne polyurethanes with tunable properties and excellent biocompatibility, EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 2016, 第 1 作者
（20） Enzymatic waterborne polyurethane towards a robust and environmentally friendly antibiofouling coating, RSC ADVANCES, 2016, 第 1 作者
（21） Peptide-Modulated Self-Assembly of Chromophores toward Biomimetic Light-Harvesting Nanoarchitectonics, ADVANCED MATERIALS, 2016, 第 2 作者
（22） Trace Solvent as a Predominant Factor To Tune Dipeptide Self-Assembly, ACS NANO, 2016, 第 2 作者
（23） UV-curable enzymatic antibacterial waterborne polyurethane coating, BIOCHEMICAL ENGINEERING JOURNAL, 2016, 第 1 作者
（24） Simple Peptide-Tuned Self-Assembly of Photosensitizers towards Anticancer Photodynamic Therapy, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 第 1 作者
（25） Co-Assembly of Heparin and Polypeptide Hybrid Nanoparticles for Biomimetic Delivery and Anti-Thrombus Therapy, SMALL, 2016, 第 3 作者
（26） Dipeptide concave nanospheres based on interfacially controlled self-assembly: from crescent to solid, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 第 5 作者
（27） Solvothermally Mediated Self-Assembly of Ultralong Peptide Nanobelts Capable of Optical Waveguiding, SMALL, 2016, 第 3 作者
（28） Molecular and mesoscale mechanism for hierarchical self-assembly of dipeptide and porphyrin light-harvesting system, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2016, 第 1 作者
（29） Mimicking Primitive Photobacteria: Sustainable Hydrogen Evolution Based on Peptide-Porphyrin Co-Assemblies with a Self-Mineralized Reaction Center, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2016, 第 1 作者
（30） Peptide self-assembly: thermodynamics and kinetics, CHEMICAL SOCIETY REVIEWS, 2016, 第 2 作者
（31） An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy, ADVANCED MATERIALS, 2016, 第 2 作者
（32） Functional architectures based on self-assembly of bio-inspired dipeptides: Structure modulation and its photoelectronic applications, ADVANCES IN COLLOID AND INTERFACE SCIENCE, 2015, 第 2 作者
（33） Preparation and characterization of castor oil-based cationic waterborne polyurethane, ADVANCED MATERIALS RESEARCH, 2015, 
（34） Peptide-Induced Hierarchical Long-Range Order and Photocatalytic Activity of Porphyrin Assemblies, ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 第 1 作者
（35） Preparation and Characterization of Epoxidized Soybean Oil-Based Paper Composite as Potential Water-Resistant Materials, JOURNAL OF APPLIED POLYMER SCIENCE, 2015, 第 2 作者
（36） Screening of lactic acid bacteria with high activities malolactic enzyme and analysis of indigenous flora in red wine, J. Chem. Pharm. Res, 2014, 第 1 作者
（37） Protective effects of two Lactobacillus plantarum strains in hyperlipidemic mice, WORLD JOURNAL OF GASTROENTEROLOGY, 2013, 第 2 作者

（1） Peptide-based supramolecular chemistry, Singapore, 2017-04, 第 2 作者
（2） Dynamic combinatorial chemistry out of equilibrium, Wiley-VCH, 2021-04, 第 1 作者
（3） Emergent catalysis by self-replicating molecule, Wiley-VCH, 2021-12, 第 1 作者

   

（ 1 ） 玛丽居里学者基金（Marie Skłodowska Individual Fellowship）, 负责人, 其他, 2019-03--2021-02
（ 2 ） 西蒙斯基金生命起源合作项目（Life Sciences-Simons Collaboration on the Origins of Life Fellowship）, 负责人, 其他, 2018-06--2019-03
（ 3 ） 高级研究项目（ERC Advanced Grant）, 参与, 其他, 2017-09--2022-08
（ 4 ） 肽调控自组装酞菁光热纳米药物的制备、应用与组装机理研究, 参与, 国家任务, 2018-01--2020-12
（ 5 ） 金属离子调控寡肽自组装及其用于光动力治疗的机制研究, 参与, 国家任务, 2018-01--2021-12

（1）Evolutionary Dynamics of Macrocyclic Self-Replicators   2022-05-26
（2）Ecological-Evolutionary Dynamics of Synthetic Replicators   2020-12-08
（3）Photocatalytically Enhanced Self-Replication of Peptides   2019-04-22