内耳发育生物学、听觉毛细胞再生、基因表达调控

2005-09--2011-04   武汉大学   硕博连读
2001-09--2005-07   武汉工程大学   学士学位

   

2022-07~现在, 中国科学院成都生物研究所, 研究员
2013-09~2021-10,西奈山医学院，Icahn School of Medicine at Mount Sinai, 博士后
2011-05~2013-05,中科院遗传与发育生物学研究所, 博士后

   

（1） The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity, NUCLEIC ACIDS RESEARCH, 2022, 第 1 作者
（2） Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation, FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 第 2 作者
（3） Chromatin remodelers and lineage-specific factors interact to target enhancers to establish proneurosensory fate within otic ectoderm, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 第 2 作者
（4） Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance, JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2021, 第 1 作者
（5） Dynamic changes in cis -regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium, NUCLEIC ACIDS RESEARCH, 2020, 第 1 作者
（6） EYA1's Conformation Specificity in Dephosphorylating Phosphothreonine in Myc and Its Activity on Myc Stabilization in Breast Cancer, MOLECULAR AND CELLULAR BIOLOGY, 2017, 第 1 作者
（7） Eya1 Interacts with Six2 and Myc to Regulate Expansion of the Nephron Progenitor Pool during Nephrogenesis, DEVELOPMENTAL CELL, 2014, 第 4 作者