General

He Li-sheng   Professor  Institute of Deep-sea Science and Engineering, Chinese Academy of Sciences
e-mail: he-lisheng@idsse.ac.cn
Address: No.28, Luhuitou Road, Sanya City,Hainan Province, P.R. China
Postcode: 57200


Research Areas

the adaptation of deep-sea macro-organisms to extrem environment. ​

Education

 Ph.D. 2007   Hong Kong University of Science and Technology
Master 2003  Peking University
Undergruate 2000  Peking University


Experience

   
Work Experience
2013- Professor, Institute of Deep-sea Science and Engineering, CAS

Publications

   
Papers
(1) “Unicorn from Hades”, a new genus of Mysidae (Malacostraca: Mysida) from the Mariana Trench, with a systematic analysis of the deep-sea mysids, Molecular Phylogenetics and Evolution, 2020-02, 第 4 作者
(2) Genomic characterization of a novel gut symbiont from the Hadal Snailfish, Front. Microbiol., 2020-01, 通讯作者
(3) Insights into the strategy of micro-environmental adaptation: Transcriptomic analysis of two alvinocaridid shrimps at a hydrothermal vent, PLoS ONE, 2020-01, 通讯作者
(4) The complete mitochondrial genome of the largest amphipod, Alicella gigantea: Insight into its phylogenetic relationships and deep sea adaptive characters, International Journal of Biological Macromolecules, 2019-12, 通讯作者
(5) The complete mitochondrial genome of the deep-sea amphipod Eurythenes magellanicus (Crustacea: Amphipoda: Lysianassidae), MITOCHONDRIAL DNA PART B, 2019-12, 通讯作者
(6) Comparative analysis of the gut microbial communities between two dominant amphipods from the Challenger Deep, Mariana Trench, Deep Sea Research Part I: Oceanagraphic Research Papers, 2019-09, 通讯作者
(7) Morphology and genome of a snailfish from the Mariana Trench provide insights into deep-sea adaptation, Nature Ecology & Evolution, 2019-04, 其他(合作组作者)
(8) International Journal of Biological Macromolecules, Geophysical research letters, 2019-04, 第 8 作者
(9) Hadal water sampling by in situ microbial filtration and fixation(ISMIFF) apparatus, Deep Sea Research Part I: Oceanagraphic Research Papers, 2019-02, 第 4 作者
(10) Characterization of the mitochondrial genome of an ancient amphipod Halice sp. MT-2017 (Pardaliscidae) from 10,908 m in the Mariana Trench., Scientific Reports, 2019, 通讯作者
(11) Toward understanding barnacle cementing by characterization of one cement protein-100kDa in Amphibalanus Amphitrite., Biochemical and biophysical research communications, 2018, 第 1 作者
(12) Ontogeny reversal and phylogenetic analysis of Turritopsis sp.5 (Cnidaria, Hydrozoa, Oceaniidae), a species endemic to Xiamen, China., PEERJ, 2018, 通讯作者
(13) Molecular characterization of a novel N-acetylneuraminate lyase from a deep-sea symbiotic Mycoplasma., Marine Drugs, 2018, 通讯作者
(14) Unique tRNA gene profile suggests paucity of nucleotide modifications in anticodons of a deep-sea symbiotic Spiroplasma., Nucleic Acids Research, 2018, 第 3 作者
(15) Rediscovery of the hadal species Amblyops magnus Birstein & Tchindonova, 1958(Crustacea: Mysida; Mysidae):first record from the Mariana Trench., Zootaxa, 2018, 第 3 作者
(16) The enigmatic genome of an obligate ancient Spiroplasma symbiont in a hadal holothurian., Applied and environmental microbiology, 2017, 第 1 作者
(17) Comparative Transcriptomic Analysis Reveals Candidate Genes and Pathways Involved in Larval Settlement of the Barnacle Megabalanus volcano, International journal of molecular sciences, 2017, 通讯作者
(18) A new species of the giant deep-sea isopod genus Bathynomus A.Milne Edwards, 1879(Crustacea, Isopoda, Cirolanidae) from Hainan Island, South China Sea., Integrative Zoology, 2017, 第 4 作者
(19) The first complete mitogenome of the South China deep-sea giant isopod Bathynomus sp. (Crustacea: Isopoda: Cirolanidae) allows insights into the early mitogenomic evolution of isopods., Ecology & Evolution, 2017, 第 5 作者
(20) Secretory locations of SIPC in Amphibalanus Amphitrite cyprids and a novel function of SIPC in biomineralization, Scientific Reports, 2016, 第 4 作者
(21) Genomic characterization of symbiotic mycoplasmas from the stomach of deep-sea isopod Bathynomus sp., Environmental Microbiology, 2016, 通讯作者
(22) P38 MAPK regulates PKAα and CUB-serine protease in Amphibalanus Amphitrite cyprids, Scientific Reports, 2015, 第 2 作者
(23) Nitric oxide inhibits larval settlement in Amphibalanus Amphitrite cyprids by repressing muscle locomotion and molting, Proteomics, 2015, 第 4 作者
(24) Characterization of two cp20k homologues in Amphibalanus Amphitrite., Plos One., 2013, 第 1 作者
(25) MKK3 was involved in larval settlement of the barnacle Amphibalanus amphitrite through activating the kinase activity of p38MAPK, Plos One, 2013, 第 2 作者
(26) Caspase-3-Dependent Apoptosis of Citreamicin ε-Induced HeLa Cells Is Associated with Reactive Oxygen Species Generation, Chem Res Toxicol., 2013, 第 2 作者
(27) Requirement of the activation of p38 MAPK to respond to the environmental settlement cues, Plos One., 2012, 第 1 作者
(28) Butenolide inhibits marine fouling by altering the primary metabolism of three target organisms., ACS Chem Biol., 2012, 第 3 作者
(29) The regulatory role of the NO/cGMP signal transduction cascade during larval attachment and metamorphosis of the barnacle Balanus (=Amphibalanus) Amphitrite., J. Exp. Boil., 2012, 第 2 作者
(30) The neuronal p35 activator of Cdk5 is a novel F-actin binding and bundling protein,, Cell Mol Life Sci., 2010, 第 1 作者


Patents



Research Interests

(1) Study on the symbiont associated with deep sea macroorganism, including community structure, metabolic pathway and interaction with host ;

(2) Combine omics and biochemistry approaches to investigate the unique metabolic pathway, regulatory pathway and protein functions of deep sea macroorganisms ;

(3) Exploitation and utilization of deep sea gene resources


Conferences

(1)Vertically transmitted symbiont in the hadal snailfish bridges Mycoplasma and Ureaplasma. Microbiology Society Annual Conference 2019
(2)Genomic characterization of the unique symbiont Ureaplasma liparidae from the gut of hadal snailfish.   15th Deep-sea Biology symposium   2018
(3)Genomic characterization of Mycoplasma symbiotic bacteria from the stomach of deep-sea isopod Bathynomus sp.   16th International  Symposium on Microbial Ecology  2016
(4)A molecular Study of the gut Content of the Bathynomus giganteus From the South China Sea    14th Deep-sea Biology symposium 2015
(5)The involvement of the activation of p38 MAPK in barnacle larval settlement.   Larval Biology   2012


Students

已指导学生

闫国永  博士研究生  070703-海洋生物学  

李俊元  博士研究生  070703-海洋生物学  

王少露  硕士研究生  070703-海洋生物学  

程项雨  硕士研究生  070703-海洋生物学  

朱方超  博士研究生  070703-海洋生物学  

连春盎  博士研究生  070703-海洋生物学  

现指导学生

廖燕雯  硕士研究生  070703-海洋生物学  

李琪  博士研究生  070703-海洋生物学  

史孟可  博士研究生  070703-海洋生物学  

Honors & Distinctions

1. National Natural Science Award 2016 the Second Prize Ranking 4th

2.“Nan Hai Ming Jia” Talent Plan 2019